Katie Copley
Affiliations: | 2019- | University of Pennsylvania, Philadelphia, PA, United States |
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Publications
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Guo L, Mann JR, Mauna JC, et al. (2023) Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains. Biorxiv : the Preprint Server For Biology |
Ervilha Pereira P, Schuermans N, Meylemans A, et al. (2023) C-terminal frameshift variant of TDP-43 with pronounced aggregation-propensity causes rimmed vacuole myopathy but not ALS/FTD. Acta Neuropathologica |
Copley KE, Shorter J. (2023) Repetitive elements in aging and neurodegeneration. Trends in Genetics : Tig |
Gleixner AM, Verdone BM, Otte CG, et al. (2022) NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility. Nature Communications. 13: 3380 |
Shen H, Yanas A, Owens MC, et al. (2022) Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation. Molecular Cell |
Copley KE, Shorter J. (2022) Flying under the radar: TMEM106B(120-254) fibrils break out in diverse neurodegenerative disorders. Cell. 185: 1290-1292 |
Hallegger M, Chakrabarti AM, Lee FCY, et al. (2021) TDP-43 condensation properties specify its RNA-binding and regulatory repertoire. Cell |
Mann JR, Gleixner AM, Mauna JC, et al. (2019) RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron |