Amandeep Girdhar

Affiliations: 
Thomas Jefferson University, Philadelphia, PA, United States 
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"Amandeep Girdhar"
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Gao J, Mewborne QT, Girdhar A, et al. (2022) Poly(ADP-ribose) promotes toxicity of arginine-rich dipeptide repeat proteins. Science Translational Medicine. 14: eabq3215
Girdhar A, Guo L. (2022) Regulating Phase Transition in Neurodegenerative Diseases by Nuclear Import Receptors. Biology. 11
Girdhar A, Bharathi V, Tiwari VR, et al. (2020) Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-43-A315T by AIM4. International Journal of Biological Macromolecules
Prasad A, Bharathi V, Sivalingam V, et al. (2019) Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis. Frontiers in Molecular Neuroscience. 12: 25
Prasad A, Sivalingam V, Bharathi V, et al. (2018) The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization. Biochimie
Verma M, Girdhar A, Patel B, et al. (2018) Q-Rich Yeast Prion [] Accelerates Aggregation of Transthyretin, a Non-Q-Rich Human Protein. Frontiers in Molecular Neuroscience. 11: 75
Prasad A, Raju G, Sivalingam V, et al. (2016) An acridine derivative, [4,5-bis{(N-carboxy methyl imidazolium)methyl}acridine] dibromide, shows anti-TDP-43 aggregation effect in ALS disease models. Scientific Reports. 6: 39490
Bharathi V, Girdhar A, Prasad A, et al. (2016) Use of ade1 & ade2 mutations for development of a versatile red/white color assay of amyloid-induced oxidative stress in Saccharomyces cerevisiae. Yeast (Chichester, England)
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