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Antoniette Michelle Maldonado-Devincci, Ph.D.

Affiliations: 
2004-2011 Psychology University of South Florida, Tampa 
 2011-2015 Bowles Center for Alcohol Studies University of North Carolina, Chapel Hill, Chapel Hill, NC 
 2016- Psychology North Carolina A&T State University, Greensboro, NC, United States 
Area:
Adolescence, Drug Addiction, Alcohol, Neuroactive Steroids
Website:
https://www.ncbi.nlm.nih.gov/sites/myncbi/1HaVgm03xsck7/bibliography/42759200/public/?sort=date&direction=descending
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"Antoniette Maldonado-Devincci"
Bio:

My current research focuses on the role of alcohol's effects modulation of particular systems in the brain, namely GABAergic neurosteroids. My current research has two overall goals. The first goal to is understand the development of neuroactive steroids during adolescence and how drug exposure during this developmental period would contribute to abnormal brain development and drug-seeking and drug-taking behavior. The second aim is to understand how alcohol dependence changes brain neurocircuitry and how these changes can be reversed by potential therapeutic intervention.

Mean distance: 17.19 (cluster 11)
 
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Parents

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Cheryl L. Kirstein grad student 2004-2011 University of South Florida
 (Repeated Binge Pattern Ethanol Administration During Adolescence or Adulthood: Long-Term Changes in Voluntary Ethanol Intake and Mesolimbic Dopamine Functionality in Male Rats.)
A Leslie Morrow post-doc 2011- UNC Chapel Hill
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Publications

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Gamble DN, Josefson CC, Hennessey MK, et al. (2019) Social interaction with an alcohol-intoxicated or cocaine-injected peer selectively alters social behaviors and drinking in adolescent male and female rats. Alcoholism, Clinical and Experimental Research
Stevenson RA, Hoffman JL, Maldonado-Devincci AM, et al. (2019) MGluR5 activity is required for the induction of ethanol behavioral sensitization and associated changes in ERK MAP kinase phosphorylation in the nucleus accumbens shell and lateral habenula. Behavioural Brain Research
Bell RL, Hauser SR, Liang T, et al. (2017) Rat animal models for screening medications to treat alcohol use disorders. Neuropharmacology
Hasirci AS, Maldonado-Devincci AM, Beattie MC, et al. (2017) Cellular GABAergic Neuroactive Steroid (3α,5α)-3-Hydroxy-Pregnan-20-One (3α,5α-THP) Immunostaining Levels Are Increased in the Ventral Tegmental Area of Human Alcohol Use Disorder Patients: A Postmortem Study. Alcoholism, Clinical and Experimental Research
Maldonado-Devincci AM, Kampov-Polevoi A, McKinley RE, et al. (2016) Chronic Intermittent Ethanol Exposure Alters Stress Effects on (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) Immunolabeling of Amygdala Neurons in C57BL/6J Mice. Frontiers in Cellular Neuroscience. 10: 40
Beattie MC, Maldonado-Devincci AM, Porcu P, et al. (2015) Voluntary ethanol consumption reduces GABAergic neuroactive steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) in the amygdala of the cynomolgus monkey. Addiction Biology
Pleil KE, Lowery-Gionta EG, Crowley NA, et al. (2015) Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala. Neuropharmacology
Maldonado-Devincci AM, Cook JB, O'Buckley TK, et al. (2014) Chronic intermittent ethanol exposure and withdrawal alters (3α,5α)-3-hydroxy-pregnan-20-one immunostaining in cortical and limbic brain regions of C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 38: 2561-71
Cook JB, Werner DF, Maldonado-Devincci AM, et al. (2014) Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5824-34
Maldonado-Devincci AM, Beattie MC, Morrow DH, et al. (2014) Reduction of circulating and selective limbic brain levels of (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) following forced swim stress in C57BL/6J mice. Psychopharmacology. 231: 3281-92
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