Huixin Xu

Boston Children's Hospital, Harvard Medical School 
Cerebrospinal fluid, neurologic disorders
"Huixin Xu"
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Dennis J. Selkoe grad student 2011-2017
Maria Kristiina Lehtinen post-doc 2018-
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Cui J, Xu H, Lehtinen MK. (2021) Macrophages on the margin: choroid plexus immune responses. Trends in Neurosciences
Xu H, Fame RM, Sadegh C, et al. (2021) Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development. Nature Communications. 12: 447
Shipley FB, Dani N, Xu H, et al. (2020) Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface. Neuron
Xu H, Lehtinen MK. (2020) Choroid Plexus Organoids: Harnessing CSF Gatekeepers for Brain Therapeutics. Cell Stem Cell. 27: 191-192
Xu H, Lehtinen MK. (2020) Cerebrospinal Fluid Magnetic Resonance Imaging: Improving Early Diagnosis of Autism and Other Neurodevelopmental Conditions. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 5: 635-637
Xu H, Rajsombath MM, Weikop P, et al. (2018) Enriched environment enhances β-adrenergic signaling to prevent microglia inflammation by amyloid-β. Embo Molecular Medicine
Yang T, Li S, Xu H, et al. (2017) Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 152-163
Xu H, Gelyana E, Rajsombath M, et al. (2016) Environmental Enrichment Potently Prevents Microglia-Mediated Neuroinflammation by Human Amyloid β-Protein Oligomers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9041-56
Lei M, Xu H, Li Z, et al. (2015) Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance. Neurobiology of Disease. 85: 111-121
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