Nicole A. Horenstein, Ph.D.

Affiliations: 
Chemistry University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Organic Chemistry, Enzymology, Bioorganic Chemistry
Website:
https://www.chem.ufl.edu/people/name/nicole-horenstein/
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"Nicole A. Horenstein"
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SNBCP

Parents

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Koji Nakanishi grad student 1986-1988 Columbia
 (Synthesis of Tunichromes)
Peter G. Schultz post-doc 1993- UC Berkeley
Vern L. Schramm post-doc 1989-1993 Albert Einstein
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Publications

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Stokes C, Pino JA, Hagan DW, et al. (2022) Betel quid: New insights into an ancient addiction. Addiction Biology. 27: e13223
Papke RL, Karaffa M, Horenstein NA, et al. (2022) Coffee and cigarettes: Modulation of high and low sensitivity α4β2 nicotinic acetylcholine receptors by n-MP, a biomarker of coffee consumption. Neuropharmacology. 216: 109173
Papke RL, Andleeb H, Stokes C, et al. (2022) Selective Agonists and Antagonists of α9 Versus α7 Nicotinic Acetylcholine Receptors. Acs Chemical Neuroscience
Horenstein NA, Stokes C, Papke RL. (2021) Sulfonium Ligands of the α7 nAChR. Molecules (Basel, Switzerland). 26
Papke RL, Horenstein NA. (2021) Therapeutic Targeting of 7 Nicotinic Acetylcholine Receptors. Pharmacological Reviews. 73: 1118-1149
Pismataro MC, Horenstein NA, Stokes C, et al. (2021) Stable desensitization of α nicotinic acetylcholine receptors by NS6740 requires interaction with S36 in the orthosteric agonist binding site. European Journal of Pharmacology. 905: 174179
Gulsevin A, Meiler J, Horenstein NA. (2020) A Computational Analysis of the Factors Governing the Dynamics of α7 nAChR and Its Homologs. Biophysical Journal
Pismataro MC, Horenstein NA, Stokes C, et al. (2020) Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation. European Journal of Medicinal Chemistry. 205: 112669
Papke RL, Garai S, Stokes C, et al. (2020) Differing activity profiles of the stereoisomers of 2,3,5,6TMP-TQS, a putative silent allosteric modulator of α7nAChR. Molecular Pharmacology
Gulsevin A, Papke RL, Horenstein N. (2020) In silico modeling of the α7 nicotinic acetylcholine receptor: new pharmacological challenges associated with multiple modes of signaling. Mini Reviews in Medicinal Chemistry
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