Tommy Liljefors, Ph.D

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1994-2008 Medicinal Chemistry Danish School of Pharmacy 
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"Tommy Liljefors"
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Parents

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Norman L. Allinger grad student (Chemistry Tree)

Children

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Per-Ola Norrby post-doc 1994-1996 Danish School of Pharmacy (Chemistry Tree)
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Publications

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Nilsson J, Nielsen EØ, Liljefors T, et al. (2012) 3-Alkyl- and 3-amido-isothiazoloquinolin-4-ones as ligands for the benzodiazepine site of GABA(A) receptors. Bioorganic Chemistry. 40: 125-30
Nilsson J, Gidlöf R, Nielsen EØ, et al. (2011) Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABA(A) receptors. Bioorganic & Medicinal Chemistry. 19: 111-21
Hald H, Ahring PK, Timmermann DB, et al. (2009) Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2. Journal of Molecular Biology. 391: 906-17
Tosco P, Ahring PK, Dyhring T, et al. (2009) Complementary three-dimensional quantitative structure-activity relationship modeling of binding affinity and functional potency: a study on alpha4beta2 nicotinic ligands. Journal of Medicinal Chemistry. 52: 2311-6
Bergmann R, Liljefors T, Sørensen MD, et al. (2009) SHOP: receptor-based scaffold HOPping by GRID-based similarity searches. Journal of Chemical Information and Modeling. 49: 658-69
Nilsson J, Nielsen EØ, Liljefors T, et al. (2008) Azaflavones compared to flavones as ligands to the benzodiazepine binding site of brain GABA(A) receptors. Bioorganic & Medicinal Chemistry Letters. 18: 5713-6
Lager E, Nilsson J, Østergaard Nielsen E, et al. (2008) Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABA(A) receptors. Bioorganic & Medicinal Chemistry. 16: 6936-48
Beich-Frandsen M, Pickering DS, Mirza O, et al. (2008) Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. Journal of Medicinal Chemistry. 51: 1459-63
Sander T, Liljefors T, Balle T. (2008) Prediction of the receptor conformation for iGluR2 agonist binding: QM/MM docking to an extensive conformational ensemble generated using normal mode analysis Journal of Molecular Graphics and Modelling. 26: 1259-1268
Harpsøe K, Liljefors T, Balle T. (2008) Prediction of the binding mode of biarylpropylsulfonamide allosteric AMPA receptor modulators based on docking, GRID molecular interaction fields and 3D-QSAR analysis. Journal of Molecular Graphics & Modelling. 26: 874-83
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