Dieter Edbauer

Centre for Neurodegenerative Diseases (DZNE), Germany 
neurodegeneration, ALS, FTD, C9orf72, TDP-43
"Dieter Edbauer"
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Hipke K, Pitter B, Hruscha A, et al. (2023) Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased , and . Frontiers in Cell and Developmental Biology. 11: 1169962
Riemenschneider H, Guo Q, Bader J, et al. (2022) Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons. Embo Reports. e53890
Gruijs da Silva LA, Simonetti F, Hutten S, et al. (2022) Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation. The Embo Journal. e108443
Mori K, Gotoh S, Yamashita T, et al. (2021) The porphyrin TMPyP4 inhibits elongation during the non-canonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene. The Journal of Biological Chemistry. 101120
Nuebling GS, Prix C, Brendel M, et al. (2021) Low-degree trisomy 21 mosaicism promotes early-onset Alzheimer disease. Neurobiology of Aging
Werner G, Damme M, Schludi M, et al. (2020) Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice. Embo Reports. e50241
Zhou Q, Mareljic N, Michaelsen M, et al. (2019) Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model. Embo Molecular Medicine. e10919
Nihei Y, Mori K, Werner G, et al. (2019) Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. Acta Neuropathologica
Parhizkar S, Arzberger T, Brendel M, et al. (2019) Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Nature Neuroscience
Zhou Q, Lehmer C, Michaelsen M, et al. (2017) Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins. Embo Molecular Medicine
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