Simona Dalin

Affiliations: 
Broad Institute (MIT/Harvard) 
Area:
Cancer biology, chemotherapy resistance, genomics
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Parents

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Michael T. Hemann grad student 2014-2019 (Telomere and Telomerase Tree)
Doug A. Lauffenburger grad student 2014-2019 (Chemistry Tree)
Rameen Beroukhim post-doc 2019-
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Publications

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Chukwu W, Lee S, Crane A, et al. (2023) Genomic sequence context differs between germline and somatic structural variants allowing for their differentiation in tumor samples without paired normals. Biorxiv : the Preprint Server For Biology
Dalin S, Webster S, Sugawara N, et al. (2023) Double-strand break repair-associated intragenic deletions and tandem duplications suggest the architecture of the repair replication fork. Biorxiv : the Preprint Server For Biology
Dalin S, Grauman-Boss B, Lauffenburger DA, et al. (2022) Collateral responses to classical cytotoxic chemotherapies are heterogeneous and sensitivities are sparse. Scientific Reports. 12: 5453
Mueller HS, Fowler CE, Dalin S, et al. (2021) Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel. Proceedings of the National Academy of Sciences of the United States of America. 118
Dalin S, Sullivan MR, Lau AN, et al. (2019) Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance. Cancer Research
Dalin S, Zhao B, Hemann MT. (2017) Abstract PR07: Collateral sensitivity in chemotherapy resistance Molecular Cancer Therapeutics. 16
Sun D, Dalin S, Hemann MT, et al. (2016) Differential selective pressure alters rate of drug resistance acquisition in heterogeneous tumor populations. Scientific Reports. 6: 36198
Wilson JL, Dalin S, Gosline S, et al. (2016) Pathway-based network modeling finds hidden genes in shRNA screen for regulators of acute lymphoblastic leukemia. Integrative Biology : Quantitative Biosciences From Nano to Macro
Dalin S, Zhao B, Hemann MT. (2016) Abstract 35: Evolution of resistance to glucocorticoid receptor agonists Clinical Cancer Research. 22: 35-35
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