Demet Araç

Affiliations: 
Biochemistry and Molecular Biology University of Chicago, Chicago, IL 
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Kordon SP, Cechova K, Bandekar SJ, et al. (2024) Structural analysis and conformational dynamics of a holo-adhesion GPCR reveal interplay between extracellular and transmembrane domains. Biorxiv : the Preprint Server For Biology
Kordon SP, Dutka P, Adamska JM, et al. (2023) Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder. Nature Communications. 14: 635
Salzman GS, Zhang S, Fernandez CG, et al. (2020) Specific and direct modulation of the interaction between adhesion GPCR GPR56/ADGRG1 and tissue transglutaminase 2 using synthetic ligands. Scientific Reports. 10: 16912
Li J, Xie Y, Cornelius S, et al. (2020) Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism. Nature Communications. 11: 2140
Leon K, Cunningham RL, Riback JA, et al. (2020) Structural basis for adhesion G protein-coupled receptor Gpr126 function. Nature Communications. 11: 194
Araç D, Li J. (2019) Teneurin Structure: Splice Variants of a Bacterial Toxin Homolog Specifies Synaptic Connections. Frontiers in Neuroscience. 13: 838
Morgan RK, Anderson GR, Araç D, et al. (2019) The expanding functional roles and signaling mechanisms of adhesion G protein-coupled receptors. Annals of the New York Academy of Sciences
Araç D, Li J. (2019) Teneurins and latrophilins: two giants meet at the synapse. Current Opinion in Structural Biology. 54: 141-151
Li J, Shalev-Benami M, Sando R, et al. (2018) Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse. Cell. 173: 735-748.e15
Salzman GS, Zhang S, Gupta A, et al. (2017) Stachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region. Proceedings of the National Academy of Sciences of the United States of America
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