Megan F Duffy

Affiliations: 
National Institutes Health (NIH) 
Area:
Parkinson’s disease, aging, genetics, iPSCs, brain organoids
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"Megan Duffy"
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Patterson JR, Hirst WD, Howe JW, et al. (2022) Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein. Npj Parkinson's Disease. 8: 61
Howe JW, Sortwell CE, Duffy MF, et al. (2021) Preformed fibrils generated from mouse alpha-synuclein produce more inclusion pathology in rats than fibrils generated from rat alpha-synuclein. Parkinsonism & Related Disorders. 89: 41-47
Landeck N, Conti Mazza M, Duffy M, et al. (2021) Stereotaxic Intracranial Delivery of Chemicals, Proteins or Viral Vectors to Study Parkinson's Disease. Journal of Visualized Experiments : Jove
Mercado NM, Stancati JA, Sortwell CE, et al. (2020) The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats. Neurobiology of Disease. 105175
Filippini A, Mutti V, Faustini G, et al. (2020) Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes. Glia
Patterson JR, Duffy MF, Kemp CJ, et al. (2019) Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils. Neurobiology of Disease. 104525
Patterson JR, Polinski NK, Duffy MF, et al. (2019) Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo. Journal of Visualized Experiments : Jove
Duffy MF, Collier TJ, Patterson JR, et al. (2018) Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson's Disease. Frontiers in Neuroscience. 12: 621
Duffy MF, Collier TJ, Patterson JR, et al. (2018) Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration. Journal of Neuroinflammation. 15: 169
Duffy MF, Collier TJ, Patterson JR, et al. (2018) Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration. Journal of Neuroinflammation. 15: 129
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