Susanne Wegmann

Affiliations: 
German Center for Neurodegenerative Disease (DZNE) 
Area:
Tau protein, Alzheimer's disease, FTD, biophysics
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"Susanne Wegmann"
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Publications

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Basheer N, Buee L, Brion JP, et al. (2024) Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models. Acta Neuropathologica Communications. 12: 52
Rodrigues S, Anglada-Huguet M, Hochgräfe K, et al. (2023) Spreading of Tau Protein Does Not Depend on Aggregation Propensity. Journal of Molecular Neuroscience : Mn
Davies C, Tulloch J, Yip E, et al. (2023) Apolipoprotein E isoform does not influence trans-synaptic spread of tau pathology in a mouse model. Brain and Neuroscience Advances. 7: 23982128231191046
Prince PR, Hochmair J, Brognaro H, et al. (2023) Initiation and modulation of Tau protein phase separation by the drug suramin. Scientific Reports. 13: 3963
Hochmair J, Exner C, Betzel C, et al. (2022) Light Microscopy and Dynamic Light Scattering to Study Liquid-Liquid Phase Separation of Tau Proteins In Vitro. Methods in Molecular Biology (Clifton, N.J.). 2551: 225-243
Diez L, Kapinos LE, Lim RYH, et al. (2022) Analysis of Tau/Nucleoporin Interactions by Surface Plasmon Resonance Spectroscopy. Methods in Molecular Biology (Clifton, N.J.). 2551: 95-109
Diez L, Kapinos LE, Hochmair J, et al. (2022) Phosphorylation but Not Oligomerization Drives the Accumulation of Tau with Nucleoporin Nup98. International Journal of Molecular Sciences. 23
Hochmair J, Exner C, Franck M, et al. (2022) Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates. The Embo Journal. e108882
Wegmann S, Biernat J, Mandelkow E. (2021) A current view on Tau protein phosphorylation in Alzheimer's disease. Current Opinion in Neurobiology. 69: 131-138
Caballero B, Bourdenx M, Luengo E, et al. (2021) Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice. Nature Communications. 12: 2238
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