Huda Y. Zoghbi
Affiliations: | Baylor College of Medicine, Houston, TX |
Area:
SCA1, SCA7, Rett's syndrome, and Math1Google:
"Huda Zoghbi"Mean distance: 14.28 (cluster 11) | S | N | B | C | P |
Cross-listing: BCM Tree
Parents
Sign in to add mentorMarvin A. Fishman | post-doc | 1982-1985 | Baylor College of Medicine |
Arthur L. Beaudet | post-doc | 1985-1988 | Baylor College of Medicine |
Children
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Publications
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Bajikar SS, Zhou J, O'Hara R, et al. (2024) Acute MeCP2 loss in adult mice reveals transcriptional and chromatin changes that precede neurological dysfunction and inform pathogenesis. Neuron |
Kim J, Tadros B, Liang YH, et al. (2024) TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse model. Nature Neuroscience |
Kim Y, McInnes J, Kim J, et al. (2024) Olfactory deficit and gastrointestinal dysfunction precede motor abnormalities in alpha-Synuclein G51D knock-in mice. Proceedings of the National Academy of Sciences of the United States of America. 121: e2406479121 |
Bajikar SS, Sztainberg Y, Trostle AJ, et al. (2024) Modeling antisense oligonucleotide therapy in MECP2 duplication syndrome human iPSC-derived neurons reveals gene expression programs responsive to MeCP2 levels. Human Molecular Genetics |
Duvick L, Southern WM, Benzow KA, et al. (2024) Mapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease. Jci Insight |
Tejwani L, Ravindra NG, Lee C, et al. (2023) Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1. Neuron |
Zhou J, Cattoglio C, Shao Y, et al. (2023) A novel pathogenic mutation of MeCP2 impairs chromatin association independent of protein levels. Genes & Development |
Duvick L, Southern WM, Benzow K, et al. (2023) Regional vulnerability in a neurodegenerative disease: Delineating SCA1 CNS and muscle therapeutic targets using a conditional mutant ATXN1 mouse. Biorxiv : the Preprint Server For Biology |
Handler HP, Duvick L, Mitchell JS, et al. (2022) Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles. Neuron |
Coffin SL, Durham MA, Nitschke L, et al. (2022) Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron |