Daniel Christian Tapken
Affiliations: | Ruhr University Bochum, Bochum, Nordrhein-Westfalen, Germany |
Area:
ionotropic glutamate receptorsWebsite:
http://www.rub.de/receptor-biochGoogle:
"Daniel Tapken"Mean distance: 106866 (cluster 21)
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Publications
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| Ung DC, Pietrancosta N, Badillo EB, et al. (2024) GRID1/GluD1 homozygous variants linked to intellectual disability and spastic paraplegia impair mGlu1/5 receptor signaling and excitatory synapses. Molecular Psychiatry |
| Gutti G, Leifeld J, Kakarla R, et al. (2023) Discovery of triazole-bridged aryl adamantane analogs as an intriguing class of multifunctional agents for treatment of Alzheimer's disease. European Journal of Medicinal Chemistry. 259: 115670 |
| Masternak M, Koch A, Laulumaa S, et al. (2022) Differences between the GluD1 and GluD2 receptors revealed by GluD1 X-ray crystallography, binding studies and molecular dynamics. The Febs Journal |
| Pan H, Steixner-Kumar AA, Seelbach A, et al. (2020) Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury. Molecular Psychiatry |
| Borycz J, Ziegler A, Borycz JA, et al. (2018) Location and functions of Inebriated in the eye. Biology Open. 7 |
| Pan H, Oliveira B, Saher G, et al. (2018) Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model. Molecular Psychiatry |
| Tapken D, Steffensen TB, Leth R, et al. (2017) The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region. Scientific Reports. 7: 46145 |
| Castillo-Gómez E, Oliveira B, Tapken D, et al. (2016) All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class. Molecular Psychiatry |
| Larsen AP, Francotte P, Frydenvang K, et al. (2016) Synthesis and pharmacology of mono-, di- and trialkyl-substituted 7-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides combined with X-ray structure analysis to understand the unexpected structure-activity relationship at AMPA receptors. Acs Chemical Neuroscience |
| Krogsgaard-Larsen N, Storgaard M, Møller C, et al. (2015) Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid. Journal of Medicinal Chemistry |