Arthur M. Brown

ChanTest, Garfield Heights, OH, United States 
Ion Channels
"Arthur Brown"
Mean distance: 17.83 (cluster 11)


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Eric Neil grad student 1961-1964 Middlesex Hospital Medical School (Physiology Academic Tree)


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Paola Perin research assistant 1993-1994 Baylor
Michael C. Andresen grad student 1975-1978 UTMB
Laura Bianchi grad student 1994-1998
Mariella De Biasi post-doc Baylor
Michael C. Andresen post-doc 1977-1979 UTMB
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Kuryshev YA, Brown AM, Duzic E, et al. (2014) Evaluating state dependence and subtype selectivity of calcium channel modulators in automated electrophysiology assays. Assay and Drug Development Technologies. 12: 110-9
Kuryshev YA, Bruening-Wright A, Brown AM, et al. (2010) Increased cardiac risk in concomitant methadone and diazepam treatment: pharmacodynamic interactions in cardiac ion channels. Journal of Cardiovascular Pharmacology. 56: 420-30
Peng S, Lacerda AE, Kirsch GE, et al. (2010) The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes. Journal of Pharmacological and Toxicological Methods. 61: 277-86
Brimecombe JC, Kirsch GE, Brown AM. (2009) Test article concentrations in the hERG assay: losses through the perfusion, solubility and stability. Journal of Pharmacological and Toxicological Methods. 59: 29-34
Wible BA, Kuryshev YA, Smith SS, et al. (2008) An ion channel library for drug discovery and safety screening on automated platforms. Assay and Drug Development Technologies. 6: 765-80
Lacerda AE, Kuryshev YA, Chen Y, et al. (2008) Alfuzosin delays cardiac repolarization by a novel mechanism. The Journal of Pharmacology and Experimental Therapeutics. 324: 427-33
Brown AM. (2005) HERG block, QT liability and sudden cardiac death. Novartis Foundation Symposium. 266: 118-31; discussion 1
Ficker E, Dennis A, Kuryshev Y, et al. (2005) HERG channel trafficking. Novartis Foundation Symposium. 266: 57-69; discussion 70
Wible BA, Hawryluk P, Ficker E, et al. (2005) HERG-Lite: a novel comprehensive high-throughput screen for drug-induced hERG risk. Journal of Pharmacological and Toxicological Methods. 52: 136-45
Kuryshev YA, Ficker E, Wang L, et al. (2005) Pentamidine-induced long QT syndrome and block of hERG trafficking. The Journal of Pharmacology and Experimental Therapeutics. 312: 316-23
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