Yana Safonova, Ph.D.

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
bioinformatics
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"Yana Safonova"
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Publications

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Watson CT, Rodriguez OL, Engelbrecht E, et al. (2023) Looking to the future of antibody genetics: resolving the roles of immunoglobulin diversity in gene regulation, function, and immunity. Genes and Immunity
Rodriguez OL, Safonova Y, Silver CA, et al. (2023) Genetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire. Nature Communications. 14: 4419
Zhou P, Song G, Liu H, et al. (2023) Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease. Immunity
He WT, Yuan M, Callaghan S, et al. (2022) Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Science Translational Medicine. 14: eabl9605
Sirupurapu V, Safonova Y, Pevzner PA. (2022) Gene prediction in the immunoglobulin loci. Genome Research. 32: 1152-1169
Safonova Y, Shin SB, Kramer L, et al. (2022) Variations in antibody repertoires correlate with vaccine responses. Genome Research
Lee JH, Toy L, Kos JT, et al. (2021) Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naïve human B cells. Npj Vaccines. 6: 113
Bhardwaj V, Pevzner PA, Rashtchian C, et al. (2021) Trace Reconstruction Problems in Computational Biology. Ieee Transactions On Information Theory. 67: 3295-3314
Peng K, Safonova Y, Shugay M, et al. (2021) Diversity in immunogenomics: the value and the challenge. Nature Methods
Safonova Y, Pevzner PA. (2020) V(DD)J recombination is an important and evolutionary conserved mechanism for generating antibodies with unusually long CDR3s. Genome Research
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