Christoph Stein

Affiliations: 
Free University of Berlin 
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"Christoph Stein"
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Publications

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Degro CE, Jiménez-Vargas NN, Tsang Q, et al. (2023) Evolving acidic microenvironments during colitis provide selective analgesic targets for a pH-sensitive opioid. Pain
Celik MÖ, Seitz V, Yergöz F, et al. (2023) Modulation of G-protein activation, calcium currents and opioid receptor phosphorylation by the pH-dependent antinociceptive agonist NFEPP. Frontiers in Molecular Neuroscience. 16: 1171855
Thies A, Sunkara V, Ray S, et al. (2023) Modelling altered signalling of G-protein coupled receptors in inflamed environment to advance drug design. Scientific Reports. 13: 607
Celik MÖ, Negrete R, Di Rosso R, et al. (2022) Amelioration of injury-induced tissue acidosis by a nonsteroidal analgesic attenuates antinociceptive effects of the pH-dependent opioid agonist NFEPP. Scientific Reports. 12: 15172
Jiménez-Vargas NN, Yu Y, Jensen DD, et al. (2021) Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects. Gut
Baamonde A, Menéndez L, González-Rodríguez S, et al. (2020) A low pKa ligand inhibits cancer-associated pain in mice by activating peripheral mu-opioid receptors. Scientific Reports. 10: 18599
Massaly N, Temp J, Machelska H, et al. (2020) Uncovering the analgesic effects of a pH-dependent mu-opioid receptor agonist using a model of non-evoked ongoing pain. Pain
Lešnik S, Hodošček M, Bren U, et al. (2020) Potential Energy Function for Fentanyl-Based Opioid Pain Killers. Journal of Chemical Information and Modeling
Stein C. (2020) Opioid analgesia: recent developments. Current Opinion in Supportive and Palliative Care. 14: 112-117
Del Vecchio G, Labuz D, Temp J, et al. (2020) Author Correction: pK of opioid ligands as a discriminating factor for side effects. Scientific Reports. 10: 4366
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