Nicholas A. Castello, Ph.D.

Neurobiology & Behavior University of California, Irvine, Irvine, CA 
"Nicholas Castello"
Mean distance: 18.94 (cluster 32)


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Frank LaFerla grad student 2013 UC Irvine
 (Targeting structural plasticity to improve Alzheimer disease-related functional deficits.)
Frank LaFerla grad student 2013 UC Irvine
 (Targeting structural plasticity to improve Alzheimer disease-related functional deficits.)
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Myczek K, Yeung ST, Castello N, et al. (2014) Hippocampal adaptive response following extensive neuronal loss in an inducible transgenic mouse model. Plos One. 9: e106009
Blurton-Jones M, Spencer B, Michael S, et al. (2014) Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models. Stem Cell Research & Therapy. 5: 46
Castello NA, Nguyen MH, Tran JD, et al. (2014) 7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss. Plos One. 9: e91453
Chabrier MA, Cheng D, Castello NA, et al. (2014) Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease. Neurobiology of Disease. 64: 107-17
Lin AJ, Castello NA, Lee G, et al. (2014) In vivo optical signatures of neuronal death in a mouse model of Alzheimer's disease. Lasers in Surgery and Medicine. 46: 27-33
Medeiros R, Castello NA, Cheng D, et al. (2014) α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles. The American Journal of Pathology. 184: 520-9
Castello NA, Green KN, LaFerla FM. (2012) Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Aβ or tau pathology. Plos One. 7: e39566
Berchtold NC, Castello N, Cotman CW. (2010) Exercise and time-dependent benefits to learning and memory. Neuroscience. 167: 588-97
Blurton-Jones M, Kitazawa M, Martinez-Coria H, et al. (2009) Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 13594-9
Roozendaal B, Castello NA, Vedana G, et al. (2008) Noradrenergic activation of the basolateral amygdala modulates consolidation of object recognition memory. Neurobiology of Learning and Memory. 90: 576-9
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