Jacob Raber, Ph.D.

Affiliations: 
Behavioral Neuroscience and Neurology Oregon Health and Science University, Portland, OR 
Area:
Aging, Alzheimer's disease, androgen receptor, sex differences, histamine, apoE, methamphetamine, irradiation, neurogenesis, cognitive function, behavioral, circadian, high fat diet-induced cognitive impairments
Website:
http://www.ohsu.edu/xd/education/schools/school-of-medicine/academic-programs/graduate-studies/faculty/grad-studies-faculty.cfm?facultyid=292
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Children

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Matthew A. Davis research assistant 2009-2012 OHSU
Reid H.J. Olsen research assistant 2010-2012 OHSU
Eileen R.S. Torres grad student OHSU
Lance A. Johnson post-doc OHSU (Cell Biology Tree)
Benjamin Zimmerman post-doc
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Publications

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Boutros SW, Zimmerman B, Nagy SC, et al. (2023) Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and baseline DNA damage in the hippocampus. Molecular Psychiatry
Kessler K, Giannisis A, Bial G, et al. (2023) Behavioral and cognitive performance of humanized APOEε3/ε3 liver mice in relation to plasma apolipoprotein E levels. Scientific Reports. 13: 1728
Kundu P, Holden S, Paraiso IL, et al. (2022) ApoE isoform-dependent effects of xanthohumol on high fat diet-induced cognitive impairments and hippocampal metabolic pathways. Frontiers in Pharmacology. 13: 954980
Shinto LH, Raber J, Mishra A, et al. (2022) A Review of Oxylipins in Alzheimer's Disease and Related Dementias (ADRD): Potential Therapeutic Targets for the Modulation of Vascular Tone and Inflammation. Metabolites. 12
Davis CM, Zhang WH, Bah TM, et al. (2022) Age-dependent cognitive impairment, hydrocephalus and leukocyte infiltration in transgenic mice with endothelial expression of human EPHX2. Npj Aging. 8: 9
Bah TM, Allen EM, Garcia-Jaramillo M, et al. (2022) GPR39 Deficiency Impairs Memory and Alters Oxylipins and Inflammatory Cytokines Without Affecting Cerebral Blood Flow in a High-Fat Diet Mouse Model of Cognitive Impairment. Frontiers in Cellular Neuroscience. 16: 893030
Winn SR, Dudley S, Scherer T, et al. (2022) Modeling the cognitive effects of diet discontinuation in adults with phenylketonuria (PKU) using pegvaliase therapy in PAH-deficient mice. Molecular Genetics and Metabolism. 136: 46-64
Holden S, Kundu P, Torres ERS, et al. (2022) Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced Behavioral Alterations and Cognitive Impairments and Insoluble Cortical Aβ42 Levels. Frontiers in Aging Neuroscience. 14: 767558
Kundu P, Zimmerman B, Quinn JF, et al. (2022) Serum Levels of α-Klotho Are Correlated with Cerebrospinal Fluid Levels and Predict Measures of Cognitive Function. Journal of Alzheimer's Disease : Jad
Boutros SW, Zimmerman B, Nagy SC, et al. (2021) Amifostine (WR-2721) Mitigates Cognitive Injury Induced by Heavy Ion Radiation in Male Mice and Alters Behavior and Brain Connectivity. Frontiers in Physiology. 12: 770502
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