Daniel Marker
Affiliations: | 2013 | School of Medicine and Dentistry | University of Rochester, Rochester, NY |
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Sign in to add mentor| Harris A. Gelbard | grad student | 2013 | Rochester | |
| (URMC-099, a Novel Kinase Inhibitor with Drug-like Properties, is Neuroprotective in Models of Human Immunodeficiency Virus Associated Neurocognitive Disorders.) | ||||
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| Saminathan P, Kevadiya BD, Marker DF, et al. (2019) Broad Spectrum Mixed Lineage Kinase Type 3 Inhibition and HIV-1 Persistence in Macrophages. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology |
| Bellizzi MJ, Hammond JW, Li H, et al. (2018) The Mixed-Lineage Kinase Inhibitor URMC-099 Protects Hippocampal Synapses in Experimental Autoimmune Encephalomyelitis. Eneuro. 5 |
| Hammond JW, Qiu WQ, Marker DF, et al. (2018) HIV Tat causes synapse loss in a mouse model of HIV-associated neurocognitive disorder that is independent of the classical complement cascade component C1q. Glia |
| Puccini JM, Marker DF, Fitzgerald T, et al. (2015) Leucine-rich repeat kinase 2 modulates neuroinflammation and neurotoxicity in models of human immunodeficiency virus 1-associated neurocognitive disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5271-83 |
| Marker DF, Lu SM, Gelbard HA. (2014) Human immunodeficiency virus Microglia in Health and Disease. 373-392 |
| Tremblay MÈ, Marker DF, Puccini JM, et al. (2013) Ultrastructure of microglia-synapse interactions in the HIV-1 Tat-injected murine central nervous system. Communicative & Integrative Biology. 6: e27670 |
| Goodfellow VS, Loweth CJ, Ravula SB, et al. (2013) Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. Journal of Medicinal Chemistry. 56: 8032-48 |
| Marker DF, Tremblay MÈ, Puccini JM, et al. (2013) The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9998-10010 |
| Marker DF, Puccini JM, Mockus TE, et al. (2012) LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein. Journal of Neuroinflammation. 9: 261 |
| Lu SM, Tremblay MÈ, King IL, et al. (2011) HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells. Plos One. 6: e23915 |