Rhianna C. Laker
Affiliations: | 2011-2015 | Cardiovascular Medicine | University of Virginia, Charlottesville, VA |
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Publications
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Gabriel BM, Altıntaş A, Smith JAB, et al. (2021) Disrupted circadian oscillations in type 2 diabetes are linked to altered rhythmic mitochondrial metabolism in skeletal muscle. Science Advances. 7: eabi9654 |
Drake JC, Wilson RJ, Laker RC, et al. (2021) Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy. Proceedings of the National Academy of Sciences of the United States of America. 118 |
Small L, Ingerslev LR, Manitta E, et al. (2021) Ablation of DNA-methyltransferase 3A in skeletal muscle does not affect energy metabolism or exercise capacity. Plos Genetics. 17: e1009325 |
Small L, Altıntaş A, Laker RC, et al. (2020) Contraction influences Per2 gene expression in skeletal muscle through a calcium-dependent pathway. The Journal of Physiology. 598: 5739-5752 |
Sato S, Basse AL, Schönke M, et al. (2019) Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis. Cell Metabolism |
Drake JC, Laker RC, Wilson RJ, et al. (2018) Exercise-induced mitophagy in skeletal muscle occurs in the absence of stabilization of Pink1 on mitochondria. Cell Cycle (Georgetown, Tex.) |
Laker RC, Drake JC, Wilson RJ, et al. (2017) Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy. Nature Communications. 8: 548 |
Yan Z, Kronemberger A, Blomme J, et al. (2017) Exercise leads to unfavourable cardiac remodelling and enhanced metabolic homeostasis in obese mice with cardiac and skeletal muscle autophagy deficiency. Scientific Reports. 7: 7894 |
Call JA, Wilson RJ, Laker RC, et al. (2017) Ulk1-mediated autophagy plays an essential role in mitochondrial remodeling and functional regeneration of skeletal muscle. American Journal of Physiology. Cell Physiology. ajpcell.00348.2016 |
Laker RC, Taddeo EP, Akhtar YN, et al. (2016) The Mitochondrial Permeability Transition Pore Regulator Cyclophilin D Exhibits Tissue-Specific Control of Metabolic Homeostasis. Plos One. 11: e0167910 |