J David Spafford

Biology University of Waterloo, Waterloo, ON, Canada 
"J Spafford"
Mean distance: 17.95 (cluster 11)
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Segura E, Mehta A, Marsolais M, et al. (2020) An ancestral maguk protein supports the modulation of mammalian voltage-gated Ca channels through a conserved Caβ-like interface. Biochimica Et Biophysica Acta. Biomembranes. 183439
Guan W, Stephens RF, Mourad O, et al. (2020) Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in Ca3 T-type channels alter the passage and block of monovalent and divalent ions. Scientific Reports. 10: 12404
Fux JE, Mehta A, Moffat J, et al. (2018) Eukaryotic Voltage-Gated Sodium Channels: On Their Origins, Asymmetries, Losses, Diversification and Adaptations. Frontiers in Physiology. 9: 1406
Chemin J, Taiakina V, Monteil A, et al. (2017) Calmodulin regulates Cav3 T-type channels at their gating brake. The Journal of Biological Chemistry
Stephens RF, Guan W, Zhorov BS, et al. (2015) Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels. Frontiers in Physiology. 6: 153
Senatore A, Spafford JD. (2015) Physiology and pathology of voltage-gated t-type calcium channels T-Type Calcium Channels in Basic and Clinical Science. 3-17
Boone AN, Senatore A, Chemin J, et al. (2014) Gd3+ and calcium sensitive, sodium leak currents are features of weak membrane-glass seals in patch clamp recordings. Plos One. 9: e98808
Dawson TF, Boone AN, Senatore A, et al. (2014) Gene splicing of an invertebrate beta subunit (LCavβ) in the N-terminal and HOOK domains and its regulation of LCav1 and LCav2 calcium channels. Plos One. 9: e92941
Senatore A, Guan W, Boone AN, et al. (2014) T-type channels become highly permeable to sodium ions using an alternative extracellular turret region (S5-P) outside the selectivity filter. The Journal of Biological Chemistry. 289: 11952-69
Senatore A, Guan W, Spafford JD. (2014) Cav3 T-type channels: regulators for gating, membrane expression, and cation selectivity. PflüGers Archiv : European Journal of Physiology. 466: 645-60
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