Brian Kevin Kaspar
Affiliations: | 2004 | University of California, San Diego, La Jolla, CA |
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"Brian Kaspar"Mean distance: 14.05 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Fred H. (Rusty) Gage | grad student | 2004 | UCSD | |
| (Retrograde viral delivery of IGF-1 prolongs survival in a mouse model of ALS.) | ||||
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Publications
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| Powers S, Likhite S, Gadalla KK, et al. (2023) Novel MeCP2 Gene Therapy is Effective in a Multicenter Study using Two Mouse Models of Rett Syndrome and is Safe in Non-human Primates. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Johnson TB, Brudvig JJ, Likhite S, et al. (2023) Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease. Frontiers in Genetics. 14: 1118649 |
| Foust KD, Wang X, McGovern VL, et al. (2022) Retraction Note: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN. Nature Biotechnology |
| Gomes C, Sequeira C, Likhite S, et al. (2022) Neurotoxic Astrocytes Directly Converted from Sporadic and Familial ALS Patient Fibroblasts Reveal Signature Diversities and miR-146a Theragnostic Potential in Specific Subtypes. Cells. 11 |
| Liao XH, Avalos P, Shelest O, et al. (2022) AAV9-MCT8 delivery at juvenile stage ameliorates neurological and behavioral deficits in a mouse model of MCT8-deficiency. Thyroid : Official Journal of the American Thyroid Association |
| Iyer CC, Chugh D, Bobbili PJ, et al. (2021) Follistatin-induced muscle hypertrophy in aged mice improves neuromuscular junction innervation and function. Neurobiology of Aging. 104: 32-41 |
| Chugh D, Iyer CC, Bobbili P, et al. (2021) Voluntary wheel running with and without follistatin overexpression improves NMJ transmission but not motor unit loss in late life of C57BL/6J mice. Neurobiology of Aging |
| White KA, Nelvagal HR, Poole TA, et al. (2021) Intracranial delivery of AAV9 gene therapy partially prevents retinal degeneration and visual deficits in CLN6-Batten disease mice. Molecular Therapy. Methods & Clinical Development. 20: 497-507 |
| Blatnik AJ, McGovern VL, Le TT, et al. (2020) Conditional deletion of SMN in cell culture identifies functional SMN alleles. Human Molecular Genetics |
| von Wittgenstein J, Zheng F, Wittmann MT, et al. (2020) Sox11 is an Activity-Regulated Gene with Dentate-Gyrus-Specific Expression Upon General Neural Activation. Cerebral Cortex (New York, N.Y. : 1991) |