Tom Claydon

2008-2012 Biomedical Physiology and Kinesiology Simon Fraser University, Burnaby, British Columbia, Canada 
"Tom Claydon"
Mean distance: 16.97 (cluster 11)
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Genge CE, Lin E, Lee L, et al. (2016) The Zebrafish Heart as a Model of Mammalian Cardiac Function. Reviews of Physiology, Biochemistry and Pharmacology
Guo J, Cheng YM, Lees-Miller JP, et al. (2015) NS1643 interacts around L529 of hERG to alter voltage sensor movement on the path to activation. Biophysical Journal. 108: 1400-13
Thouta S, Sokolov S, Abe Y, et al. (2014) Proline scan of the HERG channel S6 helix reveals the location of the intracellular pore gate. Biophysical Journal. 106: 1057-69
Hull CM, Sokolov S, Van Slyke AC, et al. (2014) Regional flexibility in the S4-S5 linker regulates hERG channel closed-state stabilization. PflüGers Archiv : European Journal of Physiology. 466: 1911-9
Shi YP, Cheng YM, Van Slyke AC, et al. (2014) External protons destabilize the activated voltage sensor in hERG channels. European Biophysics Journal : Ebj. 43: 59-69
Cheng YM, Hull CM, Niven CM, et al. (2013) Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels. The Journal of General Physiology. 142: 289-303
Jones DK, Claydon TW, Ruben PC. (2013) Extracellular protons inhibit charge immobilization in the cardiac voltage-gated sodium channel. Biophysical Journal. 105: 101-7
Jones DK, Peters CH, Allard CR, et al. (2013) Proton sensors in the pore domain of the cardiac voltage-gated sodium channel. The Journal of Biological Chemistry. 288: 4782-91
Cheng YM, Claydon TW. (2012) Voltage-dependent gating of HERG potassium channels. Frontiers in Pharmacology. 3: 83
Van Slyke AC, Cheng YM, Mafi P, et al. (2012) Proton block of the pore underlies the inhibition of hERG cardiac K+ channels during acidosis. American Journal of Physiology. Cell Physiology. 302: C1797-806
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