Jeffrey N. Savas

Affiliations: 
2015- Neurology Northwestern University, Evanston, IL 
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"Jeffrey Savas"
Mean distance: 17.43 (cluster 6)
 
SNBCP

Parents

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Sanford P. Markey grad student 2009 NYU (Chemistry Tree)
 (Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies/neuronal granules.)
Naoko Tanese grad student 2009 NYU
 (Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies/neuronal granules.)
John Yates III post-doc Scripps Institute (Chemistry Tree)

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Publications

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Liu P, Edassery SL, Ali L, et al. (2019) Long-lived metabolic enzymes in the Crystallin lens identified by pulse-labeling of mice and mass spectrometry. Elife. 8
Ruhl DA, Bomba-Warczak E, Watson ET, et al. (2019) Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways. Nature Communications. 10: 3532
Piunti A, Smith ER, Morgan MAJ, et al. (2019) CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism. Science Advances. 5: eaax2887
Kim JJ, Savas JN, Miller MT, et al. (2019) Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function. Plos One. 14: e0212553
Wortham M, Benthuysen JR, Wallace M, et al. (2018) Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function. Cell Reports. 25: 2904-2918.e8
Liu P, Thomson BR, Khalatyan N, et al. (2018) Selective permeability of mouse blood-aqueous barrier as determined by N-heavy isotope tracing and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America
Wang YZ, Savas JN. (2018) Uncovering Discrete Synaptic Proteomes to Understand Neurological Disorders. Proteomes. 6
Wang L, Zhao Z, Ozark PA, et al. (2018) Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy. Nature Medicine
He Q, Arroyo ED, Smukowski SN, et al. (2018) Critical period inhibition of NKCC1 rectifies synapse plasticity in the somatosensory cortex and restores adult tactile response maps in fragile X mice. Molecular Psychiatry
Savas JN, Wang YZ, DeNardo LA, et al. (2017) Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology. Cell Reports. 21: 2614-2627
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