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Shannath Merbs - Publications

Affiliations: 
Ophthalmology Johns Hopkins University School of Medicine, Baltimore, MD, United States 
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Wang J, Zibetti C, Shang P, Sripathi SR, Zhang P, Cano M, Hoang T, Xia S, Ji H, Merbs SL, Zack DJ, Handa JT, Sinha D, Blackshaw S, Qian J. ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration. Nature Communications. 9: 1364. PMID 29636475 DOI: 10.1038/S41467-018-03856-Y  0.535
2016 Langouet-Astrie CJ, Yang Z, Polisetti SM, Welsbie DS, Hauswirth WW, Zack DJ, Merbs SL, Enke RA. Characterization of intravitreally delivered capsid mutant AAV2-Cre vector to induce tissue-specific mutations in murine retinal ganglion cells. Experimental Eye Research. PMID 27481653 DOI: 10.1016/J.Exer.2016.07.019  0.698
2015 Oliver V, Jaffe AE, Song J, Wang G, Zhang P, Branham KE, Swaroop A, Eberhart CG, Zack DJ, Qian J, Merbs SL. Differential DNA Methylation Identified in the Blood and Retina of AMD Patients. Epigenetics : Official Journal of the Dna Methylation Society. 0. PMID 26067391 DOI: 10.1080/15592294.2015.1060388  0.492
2015 Wan J, Oliver VF, Wang G, Zhu H, Zack DJ, Merbs SL, Qian J. Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation. Bmc Genomics. 16: 49. PMID 25652663 DOI: 10.1186/S12864-015-1271-4  0.471
2013 Oliver VF, Franchina M, Jaffe AE, Branham KE, Othman M, Heckenlively JR, Swaroop A, Campochiaro B, Vote BJ, Craig JE, Saffery R, Mackey DA, Qian J, Zack DJ, Hewitt AW, ... Merbs SL, et al. Hypomethylation of the IL17RC promoter in peripheral blood leukocytes is not a hallmark of age-related macular degeneration. Cell Reports. 5: 1527-35. PMID 24373284 DOI: 10.1016/J.Celrep.2013.11.042  0.489
2013 Wahlin KJ, Enke RA, Fuller JA, Kalesnykas G, Zack DJ, Merbs SL. Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. Plos One. 8: e79140. PMID 24244436 DOI: 10.1371/Journal.Pone.0079140  0.725
2013 Wan J, Oliver VF, Zhu H, Zack DJ, Qian J, Merbs SL. Integrative analysis of tissue-specific methylation and alternative splicing identifies conserved transcription factor binding motifs. Nucleic Acids Research. 41: 8503-14. PMID 23887936 DOI: 10.1093/Nar/Gkt652  0.485
2013 Oliver VF, Wan J, Agarwal S, Zack DJ, Qian J, Merbs SL. A novel methyl-binding domain protein enrichment method for identifying genome-wide tissue-specific DNA methylation from nanogram DNA samples. Epigenetics & Chromatin. 6: 17. PMID 23759032 DOI: 10.1186/1756-8935-6-17  0.464
2013 Welsbie DS, Yang Z, Ge Y, Mitchell KL, Zhou X, Martin SE, Berlinicke CA, Hackler L, Fuller J, Fu J, Cao LH, Han B, Auld D, Xue T, Hirai S, ... ... Merbs SL, et al. Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proceedings of the National Academy of Sciences of the United States of America. 110: 4045-50. PMID 23431148 DOI: 10.1073/Pnas.1211284110  0.688
2013 Nasonkin IO, Merbs SL, Lazo K, Oliver VF, Brooks M, Patel K, Enke RA, Nellissery J, Jamrich M, Le YZ, Bharti K, Fariss RN, Rachel RA, Zack DJ, Rodriguez-Boulan EJ, et al. Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis. Development (Cambridge, England). 140: 1330-41. PMID 23406904 DOI: 10.1242/Dev.086603  0.593
2012 Hackler L, Masuda T, Oliver VF, Merbs SL, Zack DJ. Use of laser capture microdissection for analysis of retinal mRNA/miRNA expression and DNA methylation. Methods in Molecular Biology (Clifton, N.J.). 884: 289-304. PMID 22688715 DOI: 10.1007/978-1-61779-848-1_21  0.5
2012 Nickells RW, Merbs SL. The potential role of epigenetics in ocular diseases. Archives of Ophthalmology (Chicago, Ill. : 1960). 130: 508-9. PMID 22491920 DOI: 10.1001/Archopthalmol.2011.1423  0.538
2012 Merbs SL, Khan MA, Hackler L, Oliver VF, Wan J, Qian J, Zack DJ. Cell-specific DNA methylation patterns of retina-specific genes. Plos One. 7: e32602. PMID 22403679 DOI: 10.1371/Journal.Pone.0032602  0.581
2011 Xue T, Do MT, Riccio A, Jiang Z, Hsieh J, Wang HC, Merbs SL, Welsbie DS, Yoshioka T, Weissgerber P, Stolz S, Flockerzi V, Freichel M, Simon MI, Clapham DE, et al. Melanopsin signalling in mammalian iris and retina. Nature. 479: 67-73. PMID 22051675 DOI: 10.1038/Nature10567  0.669
2011 Wan J, Masuda T, Hackler L, Torres KM, Merbs SL, Zack DJ, Qian J. Dynamic usage of alternative splicing exons during mouse retina development. Nucleic Acids Research. 39: 7920-30. PMID 21724604 DOI: 10.1093/Nar/Gkr545  0.52
2000 Stockman A, Sharpe LT, Merbs S, Nathans J. Spectral sensitivities of human cone visual pigments determined in vivo and in vitro. Methods in Enzymology. 316: 626-50. PMID 10800706 DOI: 10.1016/S0076-6879(00)16754-0  0.58
1993 Johnson RL, Grant KB, Zankel TC, Boehm MF, Merbs SL, Nathans J, Nakanishi K. Cloning and expression of goldfish opsin sequences. Biochemistry. 32: 208-14. PMID 8418840 DOI: 10.1021/Bi00052A027  0.572
1993 Merbs SL, Nathans J. Role of hydroxyl-bearing amino acids in differentially tuning the absorption spectra of the human red and green cone pigments. Photochemistry and Photobiology. 58: 706-10. PMID 8284327 DOI: 10.1111/J.1751-1097.1993.Tb04956.X  0.487
1992 Merbs SL, Nathans J. Absorption spectra of human cone pigments. Nature. 356: 433-5. PMID 1557124 DOI: 10.1038/356433a0  0.538
1992 Wang Y, Macke JP, Merbs SL, Zack DJ, Klaunberg B, Bennett J, Gearhart J, Nathans J. A locus control region adjacent to the human red and green visual pigment genes. Neuron. 9: 429-40. PMID 1524826 DOI: 10.1016/0896-6273(92)90181-C  0.637
1992 Merbs SL, Nathans J. Photobleaching difference absorption spectra of human cone pigments: quantitative analysis and comparison to other methods. Photochemistry and Photobiology. 56: 869-81. PMID 1492133 DOI: 10.1111/J.1751-1097.1992.Tb09708.X  0.56
1992 Nathans J, Merbs SL, Sung CH, Weitz CJ, Wang Y. Molecular genetics of human visual pigments. Annual Review of Genetics. 26: 403-24. PMID 1482119 DOI: 10.1146/annurev.ge.26.120192.002155  0.527
1992 Merbs SL, Nathans J. Absorption spectra of the hybrid pigments responsible for anomalous color vision. Science (New York, N.Y.). 258: 464-6. PMID 1411542 DOI: 10.1126/Science.1411542  0.513
1992 Nathans J, Sung CH, Weitz CJ, Davenport CM, Merbs SL, Wang Y. Visual pigments and inherited variation in human vision. Society of General Physiologists Series. 47: 109-31. PMID 1369758  0.489
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