Shannath Merbs - Publications

Affiliations: 
Ophthalmology Johns Hopkins School of Medicine 

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Wang J, Zibetti C, Shang P, Sripathi SR, Zhang P, Cano M, Hoang T, Xia S, Ji H, Merbs SL, Zack DJ, Handa JT, Sinha D, Blackshaw S, Qian J. ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration. Nature Communications. 9: 1364. PMID 29636475 DOI: 10.1038/s41467-018-03856-y  0.68
2016 Langouet-Astrie CJ, Yang Z, Polisetti SM, Welsbie DS, Hauswirth WW, Zack DJ, Merbs SL, Enke RA. Characterization of intravitreally delivered capsid mutant AAV2-Cre vector to induce tissue-specific mutations in murine retinal ganglion cells. Experimental Eye Research. PMID 27481653 DOI: 10.1016/j.exer.2016.07.019  0.68
2016 Mahoney NR, Peng MY, Merbs SL, Grant MP. Virtual Fitting, Selection, and Cutting of Preformed Anatomic Orbital Implants. Ophthalmic Plastic and Reconstructive Surgery. PMID 27144440 DOI: 10.1097/IOP.0000000000000700  1
2016 Schein Y, Harding JC, Merbs SL, Cassard SD, Mabula K, Othman MS, West SK, Gower EW. Corneal Sensitivity and Presence of Pathogenic Organisms Among Participants Who Have Undergone Trichiasis Surgery Differ by Surgical Outcome. Cornea. PMID 26890661 DOI: 10.1097/ICO.0000000000000746  1
2016 Hu K, Babapoor-Farrokhran S, Rodrigues M, Deshpande M, Puchner B, Kashiwabuchi F, Hassan SJ, Asnaghi L, Handa JT, Merbs S, Eberhart CG, Semenza GL, Montaner S, Sodhi A. Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma. Oncotarget. PMID 26761211 DOI: 10.18632/oncotarget.6868  1
2015 Susarla SM, Duncan K, Mahoney NR, Merbs SL, Grant MP. Virtual Surgical Planning for Orbital Reconstruction. Middle East African Journal of Ophthalmology. 22: 442-6. PMID 26692714 DOI: 10.4103/0974-9233.164626  1
2015 Kanagalingam S, Wyse E, Merbs SL, Pearl MS. Fluctuating nature of an orbital venous-lymphatic anomaly in association with intracranial vascular malformations: a classical presentation. Bmj Case Reports. 2015. PMID 26438679 DOI: 10.1136/bcr-2015-211573  1
2015 Asnaghi L, Gezgin G, Tripathy A, Handa JT, Merbs SL, van der Velden PA, Jager MJ, Harbour JW, Eberhart CG. EMT-associated factors promote invasive properties of uveal melanoma cells. Molecular Vision. 21: 919-29. PMID 26321866  1
2015 Merbs SL, Oktavec KC, Munoz BE, Perlini EF, West SK, Othman MS, Gower EW. Lower Postoperative Scar Height is Associated with Increased Postoperative Trichiasis 1 Year after Bilamellar Tarsal Rotation Surgery. Ophthalmic Epidemiology. 22: 200-7. PMID 26158578 DOI: 10.3109/09286586.2015.1036299  1
2015 Hwang W, Oliver VF, Merbs SL, Zhu H, Qian J. Prediction of promoters and enhancers using multiple DNA methylation-associated features. Bmc Genomics. 16: S11. PMID 26099324 DOI: 10.1186/1471-2164-16-S7-S11  0.52
2015 Oliver V, Jaffe AE, Song J, Wang G, Zhang P, Branham KE, Swaroop A, Eberhart CG, Zack DJ, Qian J, Merbs SL. Differential DNA Methylation Identified in the Blood and Retina of AMD Patients. Epigenetics : Official Journal of the Dna Methylation Society. 0. PMID 26067391 DOI: 10.1080/15592294.2015.1060388  1
2015 Sohrab M, Abugo U, Grant M, Merbs S. Management of the eye in facial paralysis. Facial Plastic Surgery : Fps. 31: 140-4. PMID 25958900 DOI: 10.1055/s-0035-1549292  1
2015 Chang JR, Grant MP, Merbs SL. Enucleation as Endoscopic Sinus Surgery Complication. Jama Ophthalmology. 133: 850-2. PMID 25879995 DOI: 10.1001/jamaophthalmol.2015.0706  1
2015 Wan J, Oliver VF, Wang G, Zhu H, Zack DJ, Merbs SL, Qian J. Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation. Bmc Genomics. 16: 49. PMID 25652663 DOI: 10.1186/s12864-015-1271-4  1
2014 Oktavec KC, Cassard SD, Harding JC, Othman MS, Merbs SL, West SK, Gower EW. Patients' Perceptions of Trichiasis Surgery: Results from the Partnership for Rapid Elimination of Trachoma (PRET) Surgery Clinical Trial. Ophthalmic Epidemiology. 1-9. PMID 25525820 DOI: 10.3109/09286586.2014.988873  1
2014 Berli JU, Merbs SL, Grant MP. Reconstruction of periorbital soft tissue defects. Facial Plastic Surgery : Fps. 30: 561-9. PMID 25397712 DOI: 10.1055/s-0034-1395264  1
2014 Asnaghi L, Lin MH, Lim KS, Lim KJ, Tripathy A, Wendeborn M, Merbs SL, Handa JT, Sodhi A, Bar EE, Eberhart CG. Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation. Plos One. 9: e105372. PMID 25166211 DOI: 10.1371/journal.pone.0105372  1
2014 Rajaii F, Asnaghi L, Enke R, Merbs SL, Handa JT, Eberhart CG. The demethylating agent 5-Aza reduces the growth, invasiveness, and clonogenicity of uveal and cutaneous melanoma. Investigative Ophthalmology & Visual Science. 55: 6178-86. PMID 25146981 DOI: 10.1167/iovs.14-13933  1
2014 Liang J, Hur K, Merbs SL, Lane AP. Surgical and anatomic considerations in endoscopic revision of failed external dacryocystorhinostomy. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 150: 901-5. PMID 24596236 DOI: 10.1177/0194599814524700  1
2013 Oliver VF, Franchina M, Jaffe AE, Branham KE, Othman M, Heckenlively JR, Swaroop A, Campochiaro B, Vote BJ, Craig JE, Saffery R, Mackey DA, Qian J, Zack DJ, Hewitt AW, ... Merbs SL, et al. Hypomethylation of the IL17RC promoter in peripheral blood leukocytes is not a hallmark of age-related macular degeneration. Cell Reports. 5: 1527-35. PMID 24373284 DOI: 10.1016/j.celrep.2013.11.042  1
2013 Wahlin KJ, Enke RA, Fuller JA, Kalesnykas G, Zack DJ, Merbs SL. Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. Plos One. 8: e79140. PMID 24244436 DOI: 10.1371/journal.pone.0079140  1
2013 Koo JJ, Wang J, Thompson CB, Merbs SL, Grant MP. Impact of hospital volume and specialization on the cost of orbital trauma care. Ophthalmology. 120: 2741-6. PMID 24120326 DOI: 10.1016/j.ophtha.2013.07.041  1
2013 Wan J, Oliver VF, Zhu H, Zack DJ, Qian J, Merbs SL. Integrative analysis of tissue-specific methylation and alternative splicing identifies conserved transcription factor binding motifs. Nucleic Acids Research. 41: 8503-14. PMID 23887936 DOI: 10.1093/nar/gkt652  1
2013 Oliver VF, Wan J, Agarwal S, Zack DJ, Qian J, Merbs SL. A novel methyl-binding domain protein enrichment method for identifying genome-wide tissue-specific DNA methylation from nanogram DNA samples. Epigenetics & Chromatin. 6: 17. PMID 23759032 DOI: 10.1186/1756-8935-6-17  1
2013 Gower EW, West SK, Harding JC, Cassard SD, Munoz BE, Othman MS, Kello AB, Merbs SL. Trachomatous trichiasis clamp vs standard bilamellar tarsal rotation instrumentation for trichiasis surgery: results of a randomized clinical trial. Jama Ophthalmology. 131: 294-301. PMID 23494035 DOI: 10.1001/jamaophthalmol.2013.910  1
2013 Welsbie DS, Yang Z, Ge Y, Mitchell KL, Zhou X, Martin SE, Berlinicke CA, Hackler L, Fuller J, Fu J, Cao LH, Han B, Auld D, Xue T, Hirai S, ... ... Merbs SL, et al. Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proceedings of the National Academy of Sciences of the United States of America. 110: 4045-50. PMID 23431148 DOI: 10.1073/pnas.1211284110  1
2013 Nasonkin IO, Merbs SL, Lazo K, Oliver VF, Brooks M, Patel K, Enke RA, Nellissery J, Jamrich M, Le YZ, Bharti K, Fariss RN, Rachel RA, Zack DJ, Rodriguez-Boulan EJ, et al. Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis. Development (Cambridge, England). 140: 1330-41. PMID 23406904 DOI: 10.1242/dev.086603  1
2013 Asnaghi L, Handa JT, Merbs SL, Harbour JW, Eberhart CG. A role for Jag2 in promoting uveal melanoma dissemination and growth. Investigative Ophthalmology & Visual Science. 54: 295-306. PMID 23211831 DOI: 10.1167/iovs.12-10209  1
2013 Demetriades AM, Leyngold IM, D'Anna S, Eghrari AO, Emmert DG, Grant MP, Merbs SL. Intraglandular injection of botulinum toxin a reduces tear production in rabbits. Ophthalmic Plastic and Reconstructive Surgery. 29: 21-4. PMID 23128538 DOI: 10.1097/IOP.0b013e31826e8a86  1
2012 Merbs SL, Harding JC, Cassard SD, Munoz BE, West SK, Gower EW. Relationship between immediate post-operative appearance and 6-week operative outcome in trichiasis surgery. Plos Neglected Tropical Diseases. 6: e1718. PMID 22802976 DOI: 10.1371/journal.pntd.0001718  1
2012 Gower EW, West SK, Cassard SD, Munoz BE, Harding JC, Merbs SL. Definitions and standardization of a new grading scheme for eyelid contour abnormalities after trichiasis surgery. Plos Neglected Tropical Diseases. 6: e1713. PMID 22745845 DOI: 10.1371/journal.pntd.0001713  1
2012 Hackler L, Masuda T, Oliver VF, Merbs SL, Zack DJ. Use of laser capture microdissection for analysis of retinal mRNA/miRNA expression and DNA methylation. Methods in Molecular Biology (Clifton, N.J.). 884: 289-304. PMID 22688715 DOI: 10.1007/978-1-61779-848-1_21  1
2012 Nickells RW, Merbs SL. The potential role of epigenetics in ocular diseases. Archives of Ophthalmology (Chicago, Ill. : 1960). 130: 508-9. PMID 22491920 DOI: 10.1001/archopthalmol.2011.1423  1
2012 Merbs SL, Khan MA, Hackler L, Oliver VF, Wan J, Qian J, Zack DJ. Cell-specific DNA methylation patterns of retina-specific genes. Plos One. 7: e32602. PMID 22403679 DOI: 10.1371/journal.pone.0032602  1
2012 Merbs SL, Kello AB, Gelema H, West SK, Gower EW. The trachomatous trichiasis clamp: a surgical instrument designed to improve bilamellar tarsal rotation procedure outcomes. Archives of Ophthalmology (Chicago, Ill. : 1960). 130: 220-3. PMID 22332216 DOI: 10.1001/archopthalmol.2011.1657  1
2012 Asnaghi L, Ebrahimi KB, Schreck KC, Bar EE, Coonfield ML, Bell WR, Handa J, Merbs SL, Harbour JW, Eberhart CG. Notch signaling promotes growth and invasion in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 654-65. PMID 22228632 DOI: 10.1158/1078-0432.CCR-11-1406  1
2012 Sodhi A, Merbs S. Molecular Genetics of Choroidal Melanoma Retina Fifth Edition. 3: 2247-2253. DOI: 10.1016/B978-1-4557-0737-9.00141-7  1
2011 Xue T, Do MT, Riccio A, Jiang Z, Hsieh J, Wang HC, Merbs SL, Welsbie DS, Yoshioka T, Weissgerber P, Stolz S, Flockerzi V, Freichel M, Simon MI, Clapham DE, et al. Melanopsin signalling in mammalian iris and retina. Nature. 479: 67-73. PMID 22051675 DOI: 10.1038/nature10567  1
2011 Wan J, Masuda T, Hackler L, Torres KM, Merbs SL, Zack DJ, Qian J. Dynamic usage of alternative splicing exons during mouse retina development. Nucleic Acids Research. 39: 7920-30. PMID 21724604 DOI: 10.1093/nar/gkr545  1
2011 Gower EW, Merbs SL, Munoz BE, Kello AB, Alemayehu W, Imeru A, West SK. Rates and risk factors for unfavorable outcomes 6 weeks after trichiasis surgery. Investigative Ophthalmology & Visual Science. 52: 2704-11. PMID 21051704 DOI: 10.1167/iovs.10-5161  1
2009 Garibaldi DC, Merbs SL, Grant MP. Repair of orbital fractures. Ophthalmology. 116: 2265.e1; author repl. PMID 19883863 DOI: 10.1016/j.ophtha.2009.08.008  1
2009 Chu EA, Miller NR, Grant MP, Merbs S, Tufano RP, Lane AP. Surgical treatment of dysthyroid orbitopathy. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 141: 39-45. PMID 19559956 DOI: 10.1016/j.otohns.2009.04.004  1
2008 Park DJ, Garibaldi DC, Iliff NT, Grant MP, Merbs SL. Smooth nylon foil (SupraFOIL) orbital implants in orbital fractures: a case series of 181 patients. Ophthalmic Plastic and Reconstructive Surgery. 24: 266-70. PMID 18645428 DOI: 10.1097/IOP.0b013e31817e0fe0  1
2007 Garibaldi DC, Iliff NT, Grant MP, Merbs SL. Use of porous polyethylene with embedded titanium in orbital reconstruction: a review of 106 patients. Ophthalmic Plastic and Reconstructive Surgery. 23: 439-44. PMID 18030113 DOI: 10.1097/IOP.0b013e31815a1235  1
2006 Garibaldi DC, Robinson MR, Lee SS, Park DJ, Fine HF, Deitz L, D'Anna S, Yuan P, Ranson N, Grant MP, Iliff NT, Merbs SL. New corticosteroid-eluting porous polyethylene implant for the management of lower eyelid retraction: a pilot study. Ophthalmic Plastic and Reconstructive Surgery. 22: 424-9. PMID 17117094 DOI: 10.1097/01.iop.0000245487.61479.56  1
2006 Merbs SL. Management of a blind painful eye. Ophthalmology Clinics of North America. 19: 287-92. PMID 16701166 DOI: 10.1016/j.ohc.2006.02.010  1
2006 Garibaldi DC, Hindman HB, Grant MP, Iliff NT, Merbs SL. Effect of 0.5% apraclonidine on ptosis in Horner syndrome. Ophthalmic Plastic and Reconstructive Surgery. 22: 53-5. PMID 16418668 DOI: 10.1097/01.iop.0000196322.05586.6a  1
2005 Lohmann DR, Häusler T, Horsthemke B, Zeschnigk M, Parrella P, Merbs SL. Minimal region of deletion on chromosomal arm 3p25.1-p25.2 in uveal melanoma [2] (multiple letters) Cancer Research. 65: 10634. PMID 16288058 DOI: 10.1158/0008-5472.CAN-05-0748  1
2005 Malhotra AD, Parikh M, Garibaldi DC, Merbs SL, Miller NR, Murphy K. Resection of an orbital lymphangioma with the aid of an intralesional liquid polymer. Ajnr. American Journal of Neuroradiology. 26: 2630-4. PMID 16286413  1
2005 Merbs SL, West SK, West ES. Pattern of recurrence of trachomatous trichiasis after surgery surgical technique as an explanation. Ophthalmology. 112: 705-9. PMID 15808265 DOI: 10.1016/j.ophtha.2004.10.037  1
2005 Merbs SL, Green WR. Pathology of Choroidal Melanoma Retina: Fourth Edition. 1: 711-734. DOI: 10.1016/B978-0-323-02598-0.50041-0  1
2004 Stefko ST, DiBernardo C, Green WR, Merbs SL. Pleomorphic adenoma of the lacrimal gland with extensive calcification. Archives of Ophthalmology (Chicago, Ill. : 1960). 122: 778-80. PMID 15136329 DOI: 10.1001/archopht.122.5.778  1
2004 Merbs SL, Grant MP, Iliff NT. Simple outpatient postoperative analgesia using an orbital catheter after enucleation. Archives of Ophthalmology (Chicago, Ill. : 1960). 122: 349-52. PMID 15006848 DOI: 10.1001/archopht.122.3.349  1
2003 Parrella P, Fazio VM, Gallo AP, Sidransky D, Merbs SL. Fine mapping of chromosome 3 in uveal melanoma: identification of a minimal region of deletion on chromosomal arm 3p25.1-p25.2. Cancer Research. 63: 8507-10. PMID 14679017  1
2003 Cohen Y, Goldenberg-Cohen N, Parrella P, Chowers I, Merbs SL, Pe'er J, Sidransky D. Lack of BRAF mutation in primary uveal melanoma. Investigative Ophthalmology & Visual Science. 44: 2876-8. PMID 12824225 DOI: 10.1167/iovs.02-1329  1
2003 Merbs SL. A Review of Common Eyelid Conditions for the Primary Care Physician Advanced Studies in Medicine. 3: 563-570.  1
2001 Parrella P, Caballero OL, Sidransky D, Merbs SL. Detection of c-myc amplification in uveal melanoma by fluorescent in situ hybridization. Investigative Ophthalmology & Visual Science. 42: 1679-84. PMID 11431428  1
2000 Stockman A, Sharpe LT, Merbs S, Nathans J. Spectral sensitivities of human cone visual pigments determined in vivo and in vitro. Methods in Enzymology. 316: 626-50. PMID 10800706  1
1999 Merbs SL, Harris LL, Iwamoto MA, Iliff NT. Prevention of prolapsed silicone stents in lacrimal intubation using an intrasac fixation suture. Archives of Ophthalmology (Chicago, Ill. : 1960). 117: 1092-5. PMID 10448761  1
1999 Parrella P, Sidransky D, Merbs SL. Allelotype of posterior uveal melanoma: implications for a bifurcated tumor progression pathway. Cancer Research. 59: 3032-7. PMID 10397238  1
1999 Merbs SL, Sidransky D. Analysis of p16 (CDKN2/MTS-1/INK4A) alterations in primary sporadic uveal melanoma. Investigative Ophthalmology & Visual Science. 40: 779-83. PMID 10067984  1
1997 Fard AK, Merbs SL, Pieramici DJ. Optic nerve avulsion from a diving injury. American Journal of Ophthalmology. 124: 562-4. PMID 9323954  1
1996 Merbs SL, Chew C, Della NG, Chang J, Campochiaro PA, Zack DJ. Expression of BMP-4 in the murine retina Investigative Ophthalmology and Visual Science. 37: S330.  1
1994 Braiterman LT, Monokian GM, Eichinger DJ, Merbs SL, Gabriel A, Boeke JD. In-frame linker insertion mutagenesis of yeast transposon Ty1: phenotypic analysis. Gene. 139: 19-26. PMID 8112584 DOI: 10.1016/0378-1119(94)90518-5  1
1993 Johnson RL, Grant KB, Zankel TC, Boehm MF, Merbs SL, Nathans J, Nakanishi K. Cloning and expression of goldfish opsin sequences. Biochemistry. 32: 208-14. PMID 8418840  1
1993 Merbs SL, Nathans J. Role of hydroxyl-bearing amino acids in differentially tuning the absorption spectra of the human red and green cone pigments. Photochemistry and Photobiology. 58: 706-10. PMID 8284327  1
1992 Merbs SL, Nathans J. Absorption spectra of human cone pigments. Nature. 356: 433-5. PMID 1557124 DOI: 10.1038/356433a0  1
1992 Wang Y, Macke JP, Merbs SL, Zack DJ, Klaunberg B, Bennett J, Gearhart J, Nathans J. A locus control region adjacent to the human red and green visual pigment genes. Neuron. 9: 429-40. PMID 1524826 DOI: 10.1016/0896-6273(92)90181-C  1
1992 Merbs SL, Nathans J. Photobleaching difference absorption spectra of human cone pigments: quantitative analysis and comparison to other methods. Photochemistry and Photobiology. 56: 869-81. PMID 1492133  1
1992 Nathans J, Merbs SL, Sung CH, Weitz CJ, Wang Y. Molecular genetics of human visual pigments. Annual Review of Genetics. 26: 403-24. PMID 1482119 DOI: 10.1146/annurev.ge.26.120192.002155  1
1992 Merbs SL, Nathans J. Absorption spectra of the hybrid pigments responsible for anomalous color vision. Science (New York, N.Y.). 258: 464-6. PMID 1411542  1
1992 Nathans J, Sung CH, Weitz CJ, Davenport CM, Merbs SL, Wang Y. Visual pigments and inherited variation in human vision. Society of General Physiologists Series. 47: 109-31. PMID 1369758  1
1989 Hinshaw CJ, Peng G, Singh R, Spence JT, Enemark JH, Bruck M, Kristofzski J, Merbs SL, Ortega RB, Wexler PA. Molybdenum(VI)-dioxo complexes with linear and tripodal tetradentate ligands: Models for the molybdenum(VI/V) centers of the molybdenum hydroxylases and related enzymes. 1. Syntheses and structures Inorganic Chemistry. 28: 4483-4491.  1
1985 Kaul BB, Enemark JH, Merbs SL, Spence JT. Molybdenum(VI)-dioxo, molybdenum(V)-oxo, and molybdenum(IV)-oxo complexes with 2,3:8,9-dibenzo-1,4,7,10-tetrathiadecane. Models for the molybdenum binding site of the molybdenum cofactor Journal of the American Chemical Society. 107: 2885-2891.  1
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