Shiming Chen - Publications

Ophthalmology Washington University School of Medicine, St. Louis, MO, United States 

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Ruzycki PA, Tran NM, Kefalov VJ, Kolesnikov AV, Chen S. Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies. Genome Biology. 16: 171. PMID 26324254 DOI: 10.1186/s13059-015-0732-z  0.52
2014 Masuda T, Zhang X, Berlinicke C, Wan J, Yerrabelli A, Conner EA, Kjellstrom S, Bush R, Thorgeirsson SS, Swaroop A, Chen S, Zack DJ. The transcription factor GTF2IRD1 regulates the topology and function of photoreceptors by modulating photoreceptor gene expression across the retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15356-68. PMID 25392503 DOI: 10.1523/JNEUROSCI.2089-14.2014  0.52
2014 Tran NM, Chen S. Mechanisms of blindness: animal models provide insight into distinct CRX-associated retinopathies. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 1153-66. PMID 24888636 DOI: 10.1002/dvdy.24151  0.52
2014 Tran NM, Zhang A, Zhang X, Huecker JB, Hennig AK, Chen S. Mechanistically distinct mouse models for CRX-associated retinopathy. Plos Genetics. 10: e1004111. PMID 24516401 DOI: 10.1371/journal.pgen.1004111  0.52
2013 Hennig AK, Peng GH, Chen S. Transcription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression. Plos One. 8: e69721. PMID 23922782 DOI: 10.1371/journal.pone.0069721  0.52
2013 Peng GH, Chen S. Double chromatin immunoprecipitation: analysis of target co-occupancy of retinal transcription factors. Methods in Molecular Biology (Clifton, N.J.). 935: 311-28. PMID 23150378 DOI: 10.1007/978-1-62703-080-9_22  0.52
2012 Peng GH, Chen S. Revealing looping organization of mammalian photoreceptor genes using chromosome conformation capture (3C) assays. Methods in Molecular Biology (Clifton, N.J.). 884: 305-18. PMID 22688716 DOI: 10.1007/978-1-61779-848-1_22  0.52
2011 Rao RC, Hennig AK, Malik MT, Chen DF, Chen S. Epigenetic regulation of retinal development and disease. Journal of Ocular Biology, Diseases, and Informatics. 4: 121-36. PMID 23538488 DOI: 10.1007/s12177-012-9083-0  0.52
2011 Peng GH, Chen S. Active opsin loci adopt intrachromosomal loops that depend on the photoreceptor transcription factor network. Proceedings of the National Academy of Sciences of the United States of America. 108: 17821-6. PMID 22006320 DOI: 10.1073/pnas.1109209108  0.52
2011 Montana CL, Lawrence KA, Williams NL, Tran NM, Peng GH, Chen S, Corbo JC. Transcriptional regulation of neural retina leucine zipper (Nrl), a photoreceptor cell fate determinant. The Journal of Biological Chemistry. 286: 36921-31. PMID 21865162 DOI: 10.1074/jbc.M111.279026  0.52
2011 Wang Q, Song SK, Zhang H, Berkowitz BA, Chen S, Wickline SA, Chen J. Photoreceptor degeneration changes magnetic resonance imaging features in a mouse model of retinitis pigmentosa. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 65: 1793-8. PMID 21590807 DOI: 10.1002/mrm.22751  0.52
2011 de Melo J, Peng GH, Chen S, Blackshaw S. The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons. Development (Cambridge, England). 138: 2325-36. PMID 21558380 DOI: 10.1242/dev.061846  0.52
2011 Chen J, Wang Q, Chen S, Wickline SA, Song SK. In vivo diffusion tensor MRI of the mouse retina: a noninvasive visualization of tissue organization. Nmr in Biomedicine. 24: 447-51. PMID 20931570 DOI: 10.1002/nbm.1609  0.52
2010 Onishi A, Peng GH, Chen S, Blackshaw S. Pias3-dependent SUMOylation controls mammalian cone photoreceptor differentiation. Nature Neuroscience. 13: 1059-65. PMID 20729845 DOI: 10.1038/nn.2618  0.52
2010 Onishi A, Peng GH, Poth EM, Lee DA, Chen J, Alexis U, de Melo J, Chen S, Blackshaw S. The orphan nuclear hormone receptor ERRbeta controls rod photoreceptor survival. Proceedings of the National Academy of Sciences of the United States of America. 107: 11579-84. PMID 20534447 DOI: 10.1073/pnas.1000102107  0.52
2009 Onishi A, Peng GH, Hsu C, Alexis U, Chen S, Blackshaw S. Pias3-dependent SUMOylation directs rod photoreceptor development. Neuron. 61: 234-46. PMID 19186166 DOI: 10.1016/j.neuron.2008.12.006  0.52
2009 Escher P, Gouras P, Roduit R, Tiab L, Bolay S, Delarive T, Chen S, Tsai CC, Hayashi M, Zernant J, Merriam JE, Mermod N, Allikmets R, Munier FL, Schorderet DF. Mutations in NR2E3 can cause dominant or recessive retinal degenerations in the same family. Human Mutation. 30: 342-51. PMID 19006237 DOI: 10.1002/humu.20858  0.52
2008 Mali RS, Peng GH, Zhang X, Dang L, Chen S, Mitton KP. FIZ1 is part of the regulatory protein complex on active photoreceptor-specific gene promoters in vivo. Bmc Molecular Biology. 9: 87. PMID 18854042 DOI: 10.1186/1471-2199-9-87  0.52
2008 Hennig AK, Peng GH, Chen S. Regulation of photoreceptor gene expression by Crx-associated transcription factor network. Brain Research. 1192: 114-33. PMID 17662965 DOI: 10.1016/j.brainres.2007.06.036  0.52
2007 Peng GH, Chen S. Crx activates opsin transcription by recruiting HAT-containing co-activators and promoting histone acetylation. Human Molecular Genetics. 16: 2433-52. PMID 17656371 DOI: 10.1093/hmg/ddm200  0.52
2006 Dorval KM, Bobechko BP, Fujieda H, Chen S, Zack DJ, Bremner R. CHX10 targets a subset of photoreceptor genes. The Journal of Biological Chemistry. 281: 744-51. PMID 16236706 DOI: 10.1074/jbc.M509470200  0.52
2005 Peng GH, Chen S. Chromatin immunoprecipitation identifies photoreceptor transcription factor targets in mouse models of retinal degeneration: new findings and challenges. Visual Neuroscience. 22: 575-86. PMID 16332268 DOI: 10.1017/S0952523805225063  0.52
2005 Palhan VB, Chen S, Peng GH, Tjernberg A, Gamper AM, Fan Y, Chait BT, La Spada AR, Roeder RG. Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 102: 8472-7. PMID 15932940 DOI: 10.1073/pnas.0503505102  0.52
2005 Lerner LE, Peng GH, Gribanova YE, Chen S, Farber DB. Sp4 is expressed in retinal neurons, activates transcription of photoreceptor-specific genes, and synergizes with Crx. The Journal of Biological Chemistry. 280: 20642-50. PMID 15781457 DOI: 10.1074/jbc.M500957200  0.52
2005 Peng GH, Ahmad O, Ahmad F, Liu J, Chen S. The photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genes. Human Molecular Genetics. 14: 747-64. PMID 15689355 DOI: 10.1093/hmg/ddi070  0.52
2004 Rhee KD, Goureau O, Chen S, Yang XJ. Cytokine-induced activation of signal transducer and activator of transcription in photoreceptor precursors regulates rod differentiation in the developing mouse retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9779-88. PMID 15525763 DOI: 10.1523/JNEUROSCI.1785-04.2004  0.52
2004 Wang QL, Chen S, Esumi N, Swain PK, Haines HS, Peng G, Melia BM, McIntosh I, Heckenlively JR, Jacobson SG, Stone EM, Swaroop A, Zack DJ. QRX, a novel homeobox gene, modulates photoreceptor gene expression. Human Molecular Genetics. 13: 1025-40. PMID 15028672 DOI: 10.1093/hmg/ddh117  0.52
2004 Pittler SJ, Zhang Y, Chen S, Mears AJ, Zack DJ, Ren Z, Swain PK, Yao S, Swaroop A, White JB. Functional analysis of the rod photoreceptor cGMP phosphodiesterase alpha-subunit gene promoter: Nrl and Crx are required for full transcriptional activity. The Journal of Biological Chemistry. 279: 19800-7. PMID 15001570 DOI: 10.1074/jbc.M401864200  0.52
2004 Chen S, Peng GH, Wang X, Smith AC, Grote SK, Sopher BL, La Spada AR. Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization. Human Molecular Genetics. 13: 53-67. PMID 14613968 DOI: 10.1093/hmg/ddh005  0.52
2003 Yoo SY, Pennesi ME, Weeber EJ, Xu B, Atkinson R, Chen S, Armstrong DL, Wu SM, Sweatt JD, Zoghbi HY. SCA7 knockin mice model human SCA7 and reveal gradual accumulation of mutant ataxin-7 in neurons and abnormalities in short-term plasticity. Neuron. 37: 383-401. PMID 12575948 DOI: 10.1016/S0896-6273(02)01190-X  0.52
2002 Dunaief JL, King A, Esumi N, Eagen M, Dentchev T, Sung CH, Chen S, Zack DJ. Protein Phosphatase 1 binds strongly to the retinoblastoma protein but not to p107 or p130 in vitro and in vivo. Current Eye Research. 24: 392-6. PMID 12434308 DOI: 10.1076/ceyr.24.5.392.8524  0.52
2002 Wang X, Xu S, Rivolta C, Li LY, Peng GH, Swain PK, Sung CH, Swaroop A, Berson EL, Dryja TP, Chen S. Barrier to autointegration factor interacts with the cone-rod homeobox and represses its transactivation function. The Journal of Biological Chemistry. 277: 43288-300. PMID 12215455 DOI: 10.1074/jbc.M207952200  0.52
2002 Chen S, Wang QL, Xu S, Liu I, Li LY, Wang Y, Zack DJ. Functional analysis of cone-rod homeobox (CRX) mutations associated with retinal dystrophy. Human Molecular Genetics. 11: 873-84. PMID 11971869  0.52
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