205 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Li J, Seligson N, Zhang X, Johnson J, Vangundy Z, Wang D, Phelps M, Hofmeister C, Sadee W, Poi MJ. Association of Polymorphism With Overall Survival in Adult Patients With Hematologic Malignancies After Allogeneic Hematopoietic Stem Cell Transplantation. Anticancer Research. 40: 5707-5713. PMID 32988896 DOI: 10.21873/anticanres.14585  1
2020 Sadee W, Oberdick J, Wang Z. Biased Opioid Antagonists as Modulators of Opioid Dependence: Opportunities to Improve Pain Therapy and Opioid Use Management. Molecules (Basel, Switzerland). 25. PMID 32932935 DOI: 10.3390/molecules25184163  1
2019 Luzum JA, Ting C, Peterson EL, Gui H, Shugg T, Williams LK, Li L, Sadee W, Wang D, Lanfear DE. Association of Regulatory Genetic Variants for Protein Kinase Cα with Mortality and Drug Efficacy in Patients with Heart Failure. Cardiovascular Drugs and Therapy. PMID 31728800 DOI: 10.1007/s10557-019-06909-6  1
2019 Wang D, Lu R, Rempala G, Sadee W. Ligand-Free Estrogen Receptor Alpha (ESR1) as Master Regulator for the Expression of CYP3A4 and other Cytochrome P450s (CYPs) in Human Liver. Molecular Pharmacology. PMID 31399483 DOI: 10.1124/mol.119.116897  1
2019 Jabeen S, Pinsonneault JK, Sadee W, Lee SH, Zafar MM, Raja MS, Raja GK. Significant association of DRD2 enhancer variant rs12364283 with heroin addiction in a Pakistani population. Annals of Human Genetics. PMID 31025317 DOI: 10.1111/ahg.12322  1
2018 Ray B, Ozcagli E, Sadee W, Wang D. CYP2D6 haplotypes with enhancer single-nucleotide polymorphism rs5758550 and rs16947 (*2 allele): implications for CYP2D6 genotyping panels. Pharmacogenetics and Genomics. PMID 30520769 DOI: 10.1097/FPC.0000000000000363  1
2018 Lee SH, Ahn WY, Seweryn M, Sadee W. Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence. Bmc Genomics. 19: 826. PMID 30453884 DOI: 10.1186/s12864-018-5219-3  1
2018 Wang D, Hartmann K, Seweryn M, Sadee W. Interactions Between Regulatory Variants in CYP7A1 (Cholesterol 7α-Hydroxylase) Promoter and Enhancer Regions Regulate CYP7A1 Expression. Circulation. Genomic and Precision Medicine. 11: e002082. PMID 30354296 DOI: 10.1161/CIRCGEN.118.002082  1
2018 Barrie ES, Pinsonneault JK, Sadee W, Hollway JA, Handen BL, Smith T, Arnold LE, Butter E, Hansen-Kiss E, Herman GE, Aman MG. Testing genetic modifiers of behavior and response to atomoxetine in autism spectrum disorder with ADHD. Journal of Developmental and Physical Disabilities. 30: 355-371. PMID 30197492 DOI: 10.1007/s10882-018-9590-4  1
2018 Locke LW, Crouser ED, White P, Julian MW, Guirado Caceres E, Papp AC, Le VT, Sadee W, Schlesinger LS. IL-13-regulated Macrophage Polarization during Granuloma Formation in an In Vitro Human Sarcoidosis Model. American Journal of Respiratory Cell and Molecular Biology. PMID 30134122 DOI: 10.1165/rcmb.2018-0053OC  1
2018 Sá ACC, Webb A, Gong Y, McDonough CW, Shahin MH, Datta S, Langaee TY, Turner ST, Beitelshees AL, Chapman AB, Boerwinkle E, Gums JG, Scherer SE, Cooper-DeHoff RM, Sadee W, et al. Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies. Bmc Medical Genomics. 11: 55. PMID 29925376 DOI: 10.1186/s12920-018-0370-x  1
2018 Papp AC, Azad AK, Pietrzak M, Williams A, Handelman SK, Igo RP, Stein CM, Hartmann K, Schlesinger LS, Sadee W. AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection. Plos One. 13: e0198221. PMID 29847580 DOI: 10.1371/journal.pone.0198221  1
2018 Barrie ES, Lee SH, Frater JT, Kataki M, Scharre DW, Sadee W. Alpha-synuclein mRNA isoform formation and translation affected by polymorphism in the human SNCA 3'UTR. Molecular Genetics & Genomic Medicine. PMID 29730891 DOI: 10.1002/mgg3.407  1
2018 McDonough CW, Magvanjav O, Sá ACC, El Rouby NM, Dave C, Deitchman AN, Kawaguchi-Suzuki M, Mei W, Shen Y, Singh RSP, Solayman M, Bailey KR, Boerwinkle E, Chapman AB, Gums JG, ... ... Sadee W, et al. Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses). Circulation. Genomic and Precision Medicine. 11: e001854. PMID 29650764 DOI: 10.1161/CIRCGEN.117.001854  1
2017 Sá ACC, Webb A, Gong Y, McDonough CW, Datta S, Langaee TY, Turner ST, Beitelshees AL, Chapman AB, Boerwinkle E, Gums JG, Scherer SE, Cooper-DeHoff RM, Sadee W, Johnson JA. Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics. Scientific Reports. 7: 16068. PMID 29167564 DOI: 10.1038/s41598-017-16343-z  1
2017 Pyle CJ, Azad AK, Papp AC, Sadee W, Knoell DL, Schlesinger LS. Elemental Ingredients in the Macrophage Cocktail: Role of ZIP8 in Host Response to Mycobacterium tuberculosis. International Journal of Molecular Sciences. 18. PMID 29120360 DOI: 10.3390/ijms18112375  1
2017 Pinsonneault JK, Frater JT, Kompa B, Mascarenhas R, Wang D, Sadee W. Intronic SNP in ESR1 encoding human estrogen receptor alpha is associated with brain ESR1 mRNA isoform expression and behavioral traits. Plos One. 12: e0179020. PMID 28617822 DOI: 10.1371/journal.pone.0179020  1
2017 Crouser ED, White P, Guirado Caceres E, Julian MW, Papp AC, Locke LW, Sadee W, Schlesinger LS. A Novel In Vitro Human Granuloma Model of Sarcoidosis and Latent TB Infection. American Journal of Respiratory Cell and Molecular Biology. PMID 28598206 DOI: 10.1165/rcmb.2016-0321OC  1
2017 Suhy AM, Webb A, Papp AC, Geier EG, Sadee W. Expression and splicing of ABC and SLC transporters in the human blood-brain barrier measured with RNAseq. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28188910 DOI: 10.1016/j.ejps.2017.02.010  1
2017 Li L, Zhang L, Binkley PF, Sadee W, Wang D. Regulatory Variants Modulate Protein Kinase C α (PRKCA) Gene Expression in Human Heart. Pharmaceutical Research. PMID 28120175 DOI: 10.1007/s11095-017-2102-x  1
2017 Shahin MH, Sá AC, Webb A, Gong Y, Langaee T, McDonough CW, Riva A, Beitleshees AL, Chapman AB, Gums JG, Turner ST, Boerwinkle E, Scherer SE, Sadee W, Cooper-DeHoff RM, et al. Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response. Circulation. Cardiovascular Genetics. 10. PMID 28115488 DOI: 10.1161/CIRCGENETICS.116.001404  1
2017 Luzum JA, Pakyz RE, Elsey AR, Haidar CE, Peterson JF, Whirl-Carrillo M, Handelman SK, Palmer K, Pulley JM, Beller M, Schildcrout JS, Field JR, Weitzel KW, Cooper-DeHoff RM, Cavallari LH, ... ... Sadee W, et al. "The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and Metrics of Pharmacogenetic Implementations Across Diverse Healthcare Systems". Clinical Pharmacology and Therapeutics. PMID 28090649 DOI: 10.1002/cpt.630  1
2016 Hartmann K, Seweryn M, Handelman SK, Rempała GA, Sadee W. Erratum to: Non-linear interactions between candidate genes of myocardial infarction revealed in mRNA expression profiles. Bmc Genomics. 17: 988. PMID 27912746 DOI: 10.1186/s12864-016-3349-z  1
2016 Barrie ES, Hartmann K, Lee SH, Frater JT, Seweryn M, Wang D, Sadee W. The CHRNA5/CHRNA3/CHRNB4 Nicotinic Receptor Regulome: Genomic Architecture, Regulatory Variants, and Clinical Associations. Human Mutation. PMID 27758088 DOI: 10.1002/humu.23135  1
2016 Pietrzak M, Papp A, Curtis A, Handelman SK, Kataki M, Scharre DW, Rempala G, Sadee W. Gene expression profiling of brain samples from patients with Lewy body dementia. Biochemical and Biophysical Research Communications. PMID 27666482 DOI: 10.1016/j.bbrc.2016.09.114  1
2016 Hartmann K, Seweryn M, Handleman SK, Rempała GA, Sadee W. Non-linear interactions between candidate genes of myocardial infarction revealed in mRNA expression profiles. Bmc Genomics. 17: 738. PMID 27640124 DOI: 10.1186/s12864-016-3075-6  1
2016 Oberdick J, Ling Y, Phelps MA, Yudovich MS, Schilling K, Sadee W. Preferential delivery of an opioid antagonist to the fetal brain in pregnant mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 27189967 DOI: 10.1124/jpet.115.231902  1
2016 Cubells JF, Schroeder JP, Barrie ES, Manvich DF, Sadee W, Berg T, Mercer K, Stowe TA, Liles LC, Squires KE, Mezher A, Curtin P, Perdomo DL, Szot P, Weinshenker D. Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice. Plos One. 11: e0154864. PMID 27148966 DOI: 10.1371/journal.pone.0154864  1
2016 Sanford JC, Wang X, Shi J, Barrie ES, Wang D, Zhu HJ, Sadee W. Regulatory effects of genomic translocations at the human carboxylesterase-1 (CES1) gene locus. Pharmacogenetics and Genomics. PMID 26871237 DOI: 10.1097/FPC.0000000000000206  1
2016 Chhibber A, French CE, Yee SW, Gamazon ER, Theusch E, Qin X, Webb A, Papp AC, Wang A, Simmons CQ, Konkashbaev A, Chaudhry AS, Mitchel K, Stryke D, Ferrin TE, ... ... Sadee W, et al. Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines. The Pharmacogenomics Journal. PMID 26856248 DOI: 10.1038/tpj.2015.93  1
2015 Webb A, Papp AC, Curtis A, Newman LC, Pietrzak M, Seweryn M, Handelman SK, Rempala GA, Wang D, Graziosa E, Tyndale RF, Lerman C, Kelsoe JR, Mash DC, Sadee W. RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles. Bmc Genomics. 16: 990. PMID 26597164 DOI: 10.1186/s12864-015-2207-8  1
2015 Wang D, Sadee W. CYP3A4 intronic SNP rs35599367 (CYP3A4*22) alters RNA splicing. Pharmacogenetics and Genomics. PMID 26488616 DOI: 10.1097/FPC.0000000000000183  1
2015 Mascarenhas R, Pietrzak M, Smith RM, Webb A, Wang D, Papp AC, Pinsonneault JK, Seweryn M, Rempala G, Sadee W. Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms. Plos One. 10: e0136798. PMID 26331722 DOI: 10.1371/journal.pone.0136798  1
2015 Lu R, Smith RM, Seweryn M, Wang D, Hartmann K, Webb A, Sadee W, Rempala GA. Analyzing allele specific RNA expression using mixture models. Bmc Genomics. 16: 566. PMID 26231172 DOI: 10.1186/s12864-015-1749-0  1
2015 Hampson E, Phillips SD, Duff-Canning SJ, Evans KL, Merrill M, Pinsonneault JK, Sadée W, Soares CN, Steiner M. Working memory in pregnant women: Relation to estrogen and antepartum depression. Hormones and Behavior. PMID 26187710 DOI: 10.1016/j.yhbeh.2015.07.006  1
2015 Luzum JA, Theusch E, Taylor KD, Wang A, Sadee W, Binkley PF, Krauss RM, Medina MW, Kitzmiller JP. Individual and Combined Associations of Genetic Variants in CYP3A4, CYP3A5, and SLCO1B1 With Simvastatin and Simvastatin Acid Plasma Concentrations. Journal of Cardiovascular Pharmacology. 66: 80-5. PMID 26164721 DOI: 10.1097/FJC.0000000000000246  1
2015 Handelman SK, Seweryn M, Smith RM, Hartmann K, Wang D, Pietrzak M, Johnson AD, Kloczkowski A, Sadee W. Conditional entropy in variation-adjusted windows detects selection signatures associated with expression quantitative trait loci (eQTLs). Bmc Genomics. 16: S8. PMID 26111110 DOI: 10.1186/1471-2164-16-S8-S8  1
2015 Suhy A, Hartmann K, Papp AC, Wang D, Sadee W. Regulation of cholesteryl ester transfer protein expression by upstream polymorphisms: reduced expression associated with rs247616. Pharmacogenetics and Genomics. 25: 394-401. PMID 26061659 DOI: 10.1097/FPC.0000000000000151  1
2015 Birdwell KA, Decker B, Barbarino JM, Peterson JF, Stein CM, Sadee W, Wang D, Vinks AA, He Y, Swen JJ, Leeder JS, van Schaik R, Thummel KE, Klein TE, Caudle KE, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing. Clinical Pharmacology and Therapeutics. 98: 19-24. PMID 25801146 DOI: 10.1002/cpt.113  1
2015 Wang D, Sadee W. Response to paper by Kelly et al "The opioid receptor pharmacology of GSK1521498 compared to other ligands with different effects on compulsive reward-related behaviors" published in Psychopharmacology 232, 305-314, 2014. Psychopharmacology. 232: 1493-4. PMID 25740344 DOI: 10.1007/s00213-015-3892-3  1
2015 Handelman SK, Aaronson JM, Seweryn M, Voronkin I, Kwiek JJ, Sadee W, Verducci JS, Janies DA. Cladograms with Path to Event (ClaPTE): a novel algorithm to detect associations between genotypes or phenotypes using phylogenies. Computers in Biology and Medicine. 58: 1-13. PMID 25577610 DOI: 10.1016/j.compbiomed.2014.12.013  1
2014 Chhibber A, Kroetz DL, Tantisira KG, McGeachie M, Cheng C, Plenge R, Stahl E, Sadee W, Ritchie MD, Pendergrass SA. Genomic architecture of pharmacological efficacy and adverse events. Pharmacogenomics. 15: 2025-48. PMID 25521360 DOI: 10.2217/pgs.14.144  1
2014 Barrie ES, Weinshenker D, Verma A, Pendergrass SA, Lange LA, Ritchie MD, Wilson JG, Kuivaniemi H, Tromp G, Carey DJ, Gerhard GS, Brilliant MH, Hebbring SJ, Cubells JF, Pinsonneault JK, ... ... Sadee W, et al. Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity. Circulation Research. 115: 1017-25. PMID 25326128 DOI: 10.1161/CIRCRESAHA.116.304398  1
2014 Sadee W, Hartmann K, Seweryn M, Pietrzak M, Handelman SK, Rempala GA. Missing heritability of common diseases and treatments outside the protein-coding exome. Human Genetics. 133: 1199-215. PMID 25107510 DOI: 10.1007/s00439-014-1476-7  1
2014 Di Giorgio A, Smith RM, Fazio L, D'Ambrosio E, Gelao B, Tomasicchio A, Selvaggi P, Taurisano P, Quarto T, Masellis R, Rampino A, Caforio G, Popolizio T, Blasi G, Sadee W, et al. DRD2/CHRNA5 interaction on prefrontal biology and physiology during working memory. Plos One. 9: e95997. PMID 24819610 DOI: 10.1371/journal.pone.0095997  1
2014 Gadow KD, Pinsonneault JK, Perlman G, Sadee W. Association of dopamine gene variants, emotion dysregulation and ADHD in autism spectrum disorder. Research in Developmental Disabilities. 35: 1658-65. PMID 24780147 DOI: 10.1016/j.ridd.2014.04.007  1
2014 Smith RM, Banks W, Hansen E, Sadee W, Herman GE. Family-based clinical associations and functional characterization of the serotonin 2A receptor gene (HTR2A) in autism spectrum disorder. Autism Research : Official Journal of the International Society For Autism Research. 7: 459-67. PMID 24753316 DOI: 10.1002/aur.1383  1
2014 Suhy A, Hartmann K, Newman L, Papp A, Toneff T, Hook V, Sadee W. Genetic variants affecting alternative splicing of human cholesteryl ester transfer protein. Biochemical and Biophysical Research Communications. 443: 1270-4. PMID 24393849 DOI: 10.1016/j.bbrc.2013.12.127  1
2014 Leusink M, Onland-Moret NC, Asselbergs FW, Ding B, Kotti S, van Zuydam NR, Papp AC, Danchin N, Donnelly L, Morris AD, Chasman DI, Doevendans PA, Klungel OH, Ridker PM, van Gilst WH, ... ... Sadee W, et al. Cholesteryl ester transfer protein polymorphisms, statin use, and their impact on cholesterol levels and cardiovascular events. Clinical Pharmacology and Therapeutics. 95: 314-20. PMID 24080640 DOI: 10.1038/clpt.2013.194  1
2014 Wang D, Poi MJ, Sun X, Gaedigk A, Leeder JS, Sadee W. Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity. Human Molecular Genetics. 23: 268-78. PMID 23985325 DOI: 10.1093/hmg/ddt417  1
2014 Webb A, Albin A, Ye Z, Rastegar-Mojarad M, Huang K, Parvin J, Sadee W, Li L, Lin S, Xiang Y. Mining massive SNP data for identifying associated SNPs and uncovering gene relationships Acm Bcb 2014 - 5th Acm Conference On Bioinformatics, Computational Biology, and Health Informatics. 304-313. DOI: 10.1145/2649387.264939  1
2013 Geier EG, Chen EC, Webb A, Papp AC, Yee SW, Sadee W, Giacomini KM. Profiling solute carrier transporters in the human blood-brain barrier. Clinical Pharmacology and Therapeutics. 94: 636-9. PMID 24013810 DOI: 10.1038/clpt.2013.175  1
2013 Smith RM, Webb A, Papp AC, Newman LC, Handelman SK, Suhy A, Mascarenhas R, Oberdick J, Sadee W. Whole transcriptome RNA-Seq allelic expression in human brain. Bmc Genomics. 14: 571. PMID 23968248 DOI: 10.1186/1471-2164-14-571  1
2013 Sadee W. Bridging material and biological sciences: the legacy of Hans Peter Merkle. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 85: 3-4. PMID 23958312 DOI: 10.1016/j.ejpb.2013.06.026  1
2013 Pinsonneault JK, Sullivan D, Sadee W, Soares CN, Hampson E, Steiner M. Association study of the estrogen receptor gene ESR1 with postpartum depression--a pilot study. Archives of Women's Mental Health. 16: 499-509. PMID 23917948 DOI: 10.1007/s00737-013-0373-8  1
2013 Shuldiner AR, Relling MV, Peterson JF, Hicks JK, Freimuth RR, Sadee W, Pereira NL, Roden DM, Johnson JA, Klein TE, Shuldiner AR, Vesely M, Robinson SW, Ambulos N, ... ... Sadee W, et al. The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation. Clinical Pharmacology and Therapeutics. 94: 207-10. PMID 23588301 DOI: 10.1038/clpt.2013.59  1
2013 Webb A, Papp AC, Sanford JC, Huang K, Parvin JD, Sadee W. Expression of mRNA transcripts encoding membrane transporters detected with whole transcriptome sequencing of human brain and liver. Pharmacogenetics and Genomics. 23: 269-78. PMID 23492907 DOI: 10.1097/FPC.0b013e32835ff536  1
2013 Sadee W. Gene-gene-environment interactions between drugs, transporters, receptors, and metabolizing enzymes: Statins, SLCO1B1, and CYP3A4 as an example. Journal of Pharmaceutical Sciences. 102: 2924-9. PMID 23436703 DOI: 10.1002/jps.23483  1
2013 Sanford JC, Guo Y, Sadee W, Wang D. Regulatory polymorphisms in CYP2C19 affecting hepatic expression. Drug Metabolism and Drug Interactions. 28: 23-30. PMID 23412869 DOI: 10.1515/dmdi-2012-0038  1
2013 Sullivan D, Pinsonneault JK, Papp AC, Zhu H, Lemeshow S, Mash DC, Sadee W. Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction. Translational Psychiatry. 3: e222. PMID 23340505 DOI: 10.1038/tp.2012.146  1
2013 Azad AK, Curtis A, Papp A, Webb A, Knoell D, Sadee W, Schlesinger LS. Allelic mRNA expression imbalance in C-type lectins reveals a frequent regulatory SNP in the human surfactant protein A (SP-A) gene. Genes and Immunity. 14: 99-106. PMID 23328842 DOI: 10.1038/gene.2012.61  1
2013 Kitzmiller JP, Sullivan DM, Phelps MA, Wang D, Sadee W. CYP3A4/5 combined genotype analysis for predicting statin dose requirement for optimal lipid control. Drug Metabolism and Drug Interactions. 28: 59-63. PMID 23314529 DOI: 10.1515/dmdi-2012-0031  1
2013 Smith RM, Papp AC, Webb A, Ruble CL, Munsie LM, Nisenbaum LK, Kleinman JE, Lipska BK, Sadee W. Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex. Biological Psychiatry. 73: 546-54. PMID 23158458 DOI: 10.1016/j.biopsych.2012.09.028  1
2013 Duan W, Gao L, Zhao W, Leon M, Sadee W, Webb A, Resnick K, Wu X, Ramaswamy B, Cohn DE, Shapiro C, Andreassen PR, Otterson GA, Villalona-Calero MA. Assessment of FANCD2 nuclear foci formation in paraffin-embedded tumors: a potential patient-enrichment strategy for treatment with DNA interstrand crosslinking agents. Translational Research : the Journal of Laboratory and Clinical Medicine. 161: 156-64. PMID 23063585 DOI: 10.1016/j.trsl.2012.09.003  1
2012 Wang D, Sadee W. The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy. Journal of Personalized Medicine. 2: 175-91. PMID 24466438 DOI: 10.3390/jpm2040175  1
2012 Sadee W. The relevance of "missing heritability " in pharmacogenomics. Clinical Pharmacology and Therapeutics. 92: 428-30. PMID 22910439 DOI: 10.1038/clpt.2012.116  1
2012 Azad AK, Sadee W, Schlesinger LS. Innate immune gene polymorphisms in tuberculosis. Infection and Immunity. 80: 3343-59. PMID 22825450 DOI: 10.1128/IAI.00443-12  1
2012 Kitzmiller JP, Embi PJ, Manickam K, Sweet KM, Phelps MA, Jackson RD, Marsh CB, Sadee W. Program in pharmacogenomics at the Ohio State University Medical Center. Pharmacogenomics. 13: 751-6. PMID 22594506 DOI: 10.2217/pgs.12.46  1
2012 Papp AC, Pinsonneault JK, Wang D, Newman LC, Gong Y, Johnson JA, Pepine CJ, Kumari M, Hingorani AD, Talmud PJ, Shah S, Humphries SE, Sadee W. Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk. Plos One. 7: e31930. PMID 22403620 DOI: 10.1371/journal.pone.0031930  1
2012 Barrie ES, Smith RM, Sanford JC, Sadee W. mRNA transcript diversity creates new opportunities for pharmacological intervention. Molecular Pharmacology. 81: 620-30. PMID 22319206 DOI: 10.1124/mol.111.076604  1
2011 Yancey-Wrona J, Dallaire B, Bilsky E, Bath B, Burkart J, Webster L, Magiera D, Yang X, Phelps M, Sadee W. 6β-naltrexol, a peripherally selective opioid antagonist that inhibits morphine-induced slowing of gastrointestinal transit: an exploratory study. Pain Medicine (Malden, Mass.). 12: 1727-37. PMID 22123184 DOI: 10.1111/j.1526-4637.2011.01279.x  1
2011 Wang D, Para MF, Koletar SL, Sadee W. Human N-acetyltransferase 1 *10 and *11 alleles increase protein expression through distinct mechanisms and associate with sulfamethoxazole-induced hypersensitivity. Pharmacogenetics and Genomics. 21: 652-64. PMID 21878835 DOI: 10.1097/FPC.0b013e3283498ee9  1
2011 Sadee W. Pharmacogenomic biomarkers: validation needed for both the molecular genetic mechanism and clinical effect. Pharmacogenomics. 12: 675-80. PMID 21619429 DOI: 10.2217/pgs.11.23  1
2011 Sadee W. Genomics and personalized medicine. International Journal of Pharmaceutics. 415: 2-4. PMID 21539903 DOI: 10.1016/j.ijpharm.2011.04.048  1
2011 Pinsonneault JK, Han DD, Burdick KE, Kataki M, Bertolino A, Malhotra AK, Gu HH, Sadee W. Dopamine transporter gene variant affecting expression in human brain is associated with bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1644-55. PMID 21525861 DOI: 10.1038/npp.2011.45  1
2011 Kitzmiller JP, Groen DK, Phelps MA, Sadee W. Pharmacogenomic testing: relevance in medical practice: why drugs work in some patients but not in others. Cleveland Clinic Journal of Medicine. 78: 243-57. PMID 21460130 DOI: 10.3949/ccjm.78a.10145  1
2011 Smith RM, Sadee W. Synaptic signaling and aberrant RNA splicing in autism spectrum disorders. Frontiers in Synaptic Neuroscience. 3: 1. PMID 21423409 DOI: 10.3389/fnsyn.2011.00001  1
2011 Sadee W, Wang D, Papp AC, Pinsonneault JK, Smith RM, Moyer RA, Johnson AD. Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy. Clinical Pharmacology and Therapeutics. 89: 355-65. PMID 21289622 DOI: 10.1038/clpt.2010.314  1
2011 Moyer RA, Wang D, Papp AC, Smith RM, Duque L, Mash DC, Sadee W. Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 753-62. PMID 21150907 DOI: 10.1038/npp.2010.208  1
2011 Smith RM, Alachkar H, Papp AC, Wang D, Mash DC, Wang JC, Bierut LJ, Sadee W. Nicotinic α5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms. European Journal of Human Genetics : Ejhg. 19: 76-83. PMID 20700147 DOI: 10.1038/ejhg.2010.120  1
2011 Wang D, Guo Y, Wrighton SA, Cooke GE, Sadee W. Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs. The Pharmacogenomics Journal. 11: 274-86. PMID 20386561 DOI: 10.1038/tpj.2010.28  1
2010 Ni W, Ji J, Dai Z, Papp A, Johnson AJ, Ahn S, Farley KL, Lin TS, Dalton JT, Li X, Jarjoura D, Byrd JC, Sadee W, Grever MR, Phelps MA. Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition. Plos One. 5: e13792. PMID 21072184 DOI: 10.1371/journal.pone.0013792  1
2010 Atkinson EJ, McDonnell SK, Witte JS, Crawford DC, Fan Y, Fridley B, Li D, Li L, Rodin A, Sadee W, Speed T, Weiss ST, Yang J, Yerges L, Schaid DJ. Conference Scene: Lessons learned from the 5th Statistical Analysis Workshop of the Pharmacogenetics Research Network. Pharmacogenomics. 11: 297-303. PMID 20235785 DOI: 10.2217/pgs.10.5  1
2010 Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, et al. Allele-specific tumor spectrum in pten knockin mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 5142-7. PMID 20194734 DOI: 10.1073/pnas.0912524107  1
2010 Bertolino A, Taurisano P, Pisciotta NM, Blasi G, Fazio L, Romano R, Gelao B, Lo Bianco L, Lozupone M, Di Giorgio A, Caforio G, Sambataro F, Niccoli-Asabella A, Papp A, Ursini G, ... ... Sadee W, et al. Genetically determined measures of striatal D2 signaling predict prefrontal activity during working memory performance. Plos One. 5: e9348. PMID 20179754 DOI: 10.1371/journal.pone.0009348  1
2010 Sadee W. Regulatory polymorphisms in key candidate genes for disease susceptibility and drug response: a mandate for valid genetic biomarkers. Expert Review of Molecular Diagnostics. 10: 9-11. PMID 20014917 DOI: 10.1586/erm.09.72  1
2009 Sadee W. Measuring cis-acting regulatory variants genome-wide: new insights into expression genetics and disease susceptibility. Genome Medicine. 1: 116. PMID 20090894 DOI: 10.1186/gm116  1
2009 Beitelshees AL, Navare H, Wang D, Gong Y, Wessel J, Moss JI, Langaee TY, Cooper-DeHoff RM, Sadee W, Pepine CJ, Schork NJ, Johnson JA. CACNA1C gene polymorphisms, cardiovascular disease outcomes, and treatment response. Circulation. Cardiovascular Genetics. 2: 362-70. PMID 20031608 DOI: 10.1161/CIRCGENETICS.109.857839  1
2009 Blasi G, Lo Bianco L, Taurisano P, Gelao B, Romano R, Fazio L, Papazacharias A, Di Giorgio A, Caforio G, Rampino A, Masellis R, Papp A, Ursini G, Sinibaldi L, Popolizio T, ... Sadee W, et al. Functional variation of the dopamine D2 receptor gene is associated with emotional control as well as brain activity and connectivity during emotion processing in humans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14812-9. PMID 19940176 DOI: 10.1523/JNEUROSCI.3609-09.2009  1
2009 Bekaii-Saab T, Markowitz J, Prescott N, Sadee W, Heerema N, Wei L, Dai Z, Papp A, Campbell A, Culler K, Balint C, O'Neil B, Lee RM, Zalupski M, Dancey J, et al. A multi-institutional phase II study of the efficacy and tolerability of lapatinib in patients with advanced hepatocellular carcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5895-901. PMID 19737952 DOI: 10.1158/1078-0432.CCR-09-0465  1
2009 Roe BE, Tilley MR, Gu HH, Beversdorf DQ, Sadee W, Haab TC, Papp AC. Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene. Plos One. 4: e6704. PMID 19693267 DOI: 10.1371/journal.pone.0006704  1
2009 Bertolino A, Fazio L, Di Giorgio A, Blasi G, Romano R, Taurisano P, Caforio G, Sinibaldi L, Ursini G, Popolizio T, Tirotta E, Papp A, Dallapiccola B, Borrelli E, Sadee W. Genetically determined interaction between the dopamine transporter and the D2 receptor on prefronto-striatal activity and volume in humans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1224-34. PMID 19176830 DOI: 10.1523/JNEUROSCI.4858-08.2009  1
2009 Pham AN, Wang J, Fang J, Gao X, Zhang Y, Blower PE, Sadée W, Huang Y. Pharmacogenomics approach reveals MRP1 (ABCC1)-mediated resistance to geldanamycins. Pharmaceutical Research. 26: 936-45. PMID 19067123 DOI: 10.1007/s11095-008-9796-8  1
2009 Johnson AD, Gong Y, Wang D, Langaee TY, Shin J, Cooper-Dehoff RM, Schork NJ, Binkley P, Pepine CJ, Johnson JA, Sadee W. Promoter polymorphisms in ACE (angiotensin I-converting enzyme) associated with clinical outcomes in hypertension. Clinical Pharmacology and Therapeutics. 85: 36-44. PMID 18946466 DOI: 10.1038/clpt.2008.194  1
2009 Bertolino A, Fazio L, Caforio G, Blasi G, Rampino A, Romano R, Di Giorgio A, Taurisano P, Papp A, Pinsonneault J, Wang D, Nardini M, Popolizio T, Sadee W. Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia. Brain : a Journal of Neurology. 132: 417-25. PMID 18829695 DOI: 10.1093/brain/awn248  1
2008 Alachkar H, Kataki M, Scharre DW, Papp A, Sadee W. Allelic mRNA expression of sortilin-1 (SORL1) mRNA in Alzheimer's autopsy brain tissues. Neuroscience Letters. 448: 120-4. PMID 18938222 DOI: 10.1016/j.neulet.2008.10.034  1
2008 Sadee W. Drug therapy and personalized health care: pharmacogenomics in perspective. Pharmaceutical Research. 25: 2713-9. PMID 18726676 DOI: 10.1007/s11095-008-9702-4  1
2008 Johnson AD, Zhang Y, Papp AC, Pinsonneault JK, Lim JE, Saffen D, Dai Z, Wang D, Sadée W. Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues. Pharmacogenetics and Genomics. 18: 781-91. PMID 18698231 DOI: 10.1097/FPC.0b013e3283050107  1
2008 Dai Z, Papp AC, Wang D, Hampel H, Sadee W. Genotyping panel for assessing response to cancer chemotherapy. Bmc Medical Genomics. 1: 24. PMID 18547414 DOI: 10.1186/1755-8794-1-24  1
2008 Wang D, Chen H, Momary KM, Cavallari LH, Johnson JA, Sadée W. Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement. Blood. 112: 1013-21. PMID 18523153 DOI: 10.1182/blood-2008-03-144899  0.36
2008 Besecker B, Bao S, Bohacova B, Papp A, Sadee W, Knoell DL. The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L1127-36. PMID 18390834 DOI: 10.1152/ajplung.00057.2008  1
2008 Blower PE, Chung JH, Verducci JS, Lin S, Park JK, Dai Z, Liu CG, Schmittgen TD, Reinhold WC, Croce CM, Weinstein JN, Sadee W. MicroRNAs modulate the chemosensitivity of tumor cells. Molecular Cancer Therapeutics. 7: 1-9. PMID 18187804 DOI: 10.1158/1535-7163.MCT-07-0573  1
2007 Liu J, Buskirk J, Santangelo J, Deiter RJ, Papp A, Cooke GE, Sadee W, Kamal J. Data mining tools for genotype-phenotype correlation. Amia ... Annual Symposium Proceedings / Amia Symposium. Amia Symposium. 1037. PMID 18694135  1
2007 Zhang Y, Bertolino A, Fazio L, Blasi G, Rampino A, Romano R, Lee ML, Xiao T, Papp A, Wang D, Sadée W. Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory. Proceedings of the National Academy of Sciences of the United States of America. 104: 20552-7. PMID 18077373 DOI: 10.1073/pnas.0707106104  1
2007 Liu R, Blower PE, Pham AN, Fang J, Dai Z, Wise C, Green B, Teitel CH, Ning B, Ling W, Lyn-Cook BD, Kadlubar FF, Sadée W, Huang Y. Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin. Molecular Pharmacology. 72: 1637-46. PMID 17875604 DOI: 10.1124/mol.107.039644  1
2007 Beitelshees AL, Gong Y, Wang D, Schork NJ, Cooper-Dehoff RM, Langaee TY, Shriver MD, Sadee W, Knot HJ, Pepine CJ, Johnson JA. KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST). Pharmacogenetics and Genomics. 17: 719-29. PMID 17700361 DOI: 10.1097/FPC.0b013e32810f2e3c  1
2007 Blower PE, Verducci JS, Lin S, Zhou J, Chung JH, Dai Z, Liu CG, Reinhold W, Lorenzi PL, Kaldjian EP, Croce CM, Weinstein JN, Sadee W. MicroRNA expression profiles for the NCI-60 cancer cell panel. Molecular Cancer Therapeutics. 6: 1483-91. PMID 17483436 DOI: 10.1158/1535-7163.MCT-07-0009  1
2007 Huang Y, Blower PE, Liu R, Dai Z, Pham AN, Moon H, Fang J, Sadée W. Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1. Pharmaceutical Research. 24: 1702-12. PMID 17457659 DOI: 10.1007/s11095-007-9300-x  1
2007 Lim JE, Pinsonneault J, Sadee W, Saffen D. Tryptophan hydroxylase 2 (TPH2) haplotypes predict levels of TPH2 mRNA expression in human pons. Molecular Psychiatry. 12: 491-501. PMID 17453063 DOI: 10.1038/sj.mp.4001923  1
2007 Dai Z, Huang Y, Sadee W, Blower P. Chemoinformatics analysis identifies cytotoxic compounds susceptible to chemoresistance mediated by glutathione and cystine/glutamate transport system xc-. Journal of Medicinal Chemistry. 50: 1896-906. PMID 17367118 DOI: 10.1021/jm060960h  1
2007 Wang D, Sun X, Sadee W. Different effects of opioid antagonists on mu-, delta-, and kappa-opioid receptors with and without agonist pretreatment. The Journal of Pharmacology and Experimental Therapeutics. 321: 544-52. PMID 17267582 DOI: 10.1124/jpet.106.118810  1
2007 Cao X, Fang L, Gibbs S, Huang Y, Dai Z, Wen P, Zheng X, Sadee W, Sun D. Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia. Cancer Chemotherapy and Pharmacology. 59: 495-505. PMID 16906425 DOI: 10.1007/s00280-006-0291-9  1
2007 Dai Z, Sadee W, Blower P. Chemogenomics of sensitivity and resistance to anticancer drugs Current Pharmacogenomics. 5: 11-19. DOI: 10.2174/157016007780077158  1
2007 Pinsonneault J, Sadée W. Sex Differences in Pharmacogenomics as a Tool to Study CNS Disorders Sex Differences in the Brain: From Genes to Behavior. DOI: 10.1093/acprof:oso/9780195311587.003.0005  1
2006 Dai Z, Liu S, Marcucci G, Sadee W. 5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer). Biochemical and Biophysical Research Communications. 351: 455-61. PMID 17064661 DOI: 10.1016/j.bbrc.2006.10.055  1
2006 Wang D, Sadée W. Searching for polymorphisms that affect gene expression and mRNA processing: example ABCB1 (MDR1). The Aaps Journal. 8: E515-20. PMID 17025270 DOI: 10.1208/aapsj080361  0.36
2006 Wang Y, Dai Z, Sadee W, Hancock WS. A pharmacoproteomics study of the cancer cell line EKVX using capillary-LC/MS/MS. Molecular Pharmaceutics. 3: 566-78. PMID 17009856 DOI: 10.1021/mp060002b  1
2006 Wang D, Papp AC, Binkley PF, Johnson JA, Sadée W. Highly variable mRNA expression and splicing of L-type voltage-dependent calcium channel alpha subunit 1C in human heart tissues. Pharmacogenetics and Genomics. 16: 735-45. PMID 17001293 DOI: 10.1097/01.fpc.0000230119.34205.8a  1
2006 Sadée W, Bohn L. How specific are "target-specific" drugs? Celecoxib as a case in point. Molecular Interventions. 6: 196-8. PMID 16960141 DOI: 10.1124/mi.6.4.5  1
2006 Pinsonneault JK, Papp AC, Sadée W. Allelic mRNA expression of X-linked monoamine oxidase a (MAOA) in human brain: dissection of epigenetic and genetic factors. Human Molecular Genetics. 15: 2636-49. PMID 16893905 DOI: 10.1093/hmg/ddl192  1
2006 Krejsa C, Rogge M, Sadee W. Protein therapeutics: new applications for pharmacogenetics. Nature Reviews. Drug Discovery. 5: 507-21. PMID 16763661 DOI: 10.1038/nrd2039  1
2006 Lucas JL, Wang D, Sadée W. Calmodulin binding to peptides derived from the i3 loop of muscarinic receptors. Pharmaceutical Research. 23: 647-53. PMID 16552497 DOI: 10.1007/11095-006-9784-9  0.36
2006 Lim JE, Papp A, Pinsonneault J, Sadée W, Saffen D. Allelic expression of serotonin transporter (SERT) mRNA in human pons: lack of correlation with the polymorphism SERTLPR. Molecular Psychiatry. 11: 649-62. PMID 16432527 DOI: 10.1038/sj.mp.4001797  1
2006 Anderle P, Nielsen CU, Pinsonneault J, Krog PL, Brodin B, Sadée W. Genetic variants of the human dipeptide transporter PEPT1. The Journal of Pharmacology and Experimental Therapeutics. 316: 636-46. PMID 16258023 DOI: 10.1124/jpet.105.094615  1
2006 Dougherty D, Stahlberg E, Sadee W. Network analysis using transitive closure: New methods for exploring networks Journal of Statistical Computation and Simulation. 76: 539-551. DOI: 10.1080/10629360500107857  1
2005 Wang D, Johnson AD, Papp AC, Kroetz DL, Sadée W. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenetics and Genomics. 15: 693-704. PMID 16141795  1
2005 Zhang Y, Wang D, Johnson AD, Papp AC, Sadée W. Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G. The Journal of Biological Chemistry. 280: 32618-24. PMID 16046395 DOI: 10.1074/jbc.M504942200  0.36
2005 Zhang Y, Wang D, Sadée W. Calmodulin interaction with peptides from G-protein coupled receptors measured with S-Tag labeling. Biochemical and Biophysical Research Communications. 333: 390-5. PMID 15950946 DOI: 10.1016/j.bbrc.2005.05.129  0.36
2005 Frank NY, Margaryan A, Huang Y, Schatton T, Waaga-Gasser AM, Gasser M, Sayegh MH, Sadee W, Frank MH. ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. Cancer Research. 65: 4320-33. PMID 15899824 DOI: 10.1158/0008-5472.CAN-04-3327  1
2005 Johnson AD, Wang D, Sadee W. Polymorphisms affecting gene regulation and mRNA processing: broad implications for pharmacogenetics. Pharmacology & Therapeutics. 106: 19-38. PMID 15781120 DOI: 10.1016/j.pharmthera.2004.11.001  1
2005 Wang D, Sun X, Bohn LM, Sadée W. Opioid receptor homo- and heterodimerization in living cells by quantitative bioluminescence resonance energy transfer. Molecular Pharmacology. 67: 2173-84. PMID 15778451 DOI: 10.1124/mol.104.010272  1
2005 Raehal KM, Lowery JJ, Bhamidipati CM, Paolino RM, Blair JR, Wang D, Sadée W, Bilsky EJ. In vivo characterization of 6beta-naltrexol, an opioid ligand with less inverse agonist activity compared with naltrexone and naloxone in opioid-dependent mice. The Journal of Pharmacology and Experimental Therapeutics. 313: 1150-62. PMID 15716384 DOI: 10.1124/jpet.104.082966  0.36
2005 Sadée W, Wang D, Bilsky EJ. Basal opioid receptor activity, neutral antagonists, and therapeutic opportunities. Life Sciences. 76: 1427-37. PMID 15680308 DOI: 10.1016/j.lfs.2004.10.024  0.36
2005 Bahadduri PM, D'Souza VM, Pinsonneault JK, Sadée W, Bao S, Knoell DL, Swaan PW. Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium. American Journal of Respiratory Cell and Molecular Biology. 32: 319-25. PMID 15626774 DOI: 10.1165/rcmb.2004-0322OC  1
2005 Becker JB, Arnold AP, Berkley KJ, Blaustein JD, Eckel LA, Hampson E, Herman JP, Marts S, Sadee W, Steiner M, Taylor J, Young E. Strategies and methods for research on sex differences in brain and behavior. Endocrinology. 146: 1650-73. PMID 15618360 DOI: 10.1210/en.2004-1142  1
2004 Landowski CP, Anderle P, Sun D, Sadee W, Amidon GL. Transporter and ion channel gene expression after Caco-2 cell differentiation using 2 different microarray technologies. The Aaps Journal. 6: e21. PMID 15760106 DOI: 10.1208/aapsj060321  1
2004 Dai Z, Huang Y, Sadée W. Growth factor signaling and resistance to cancer chemotherapy. Current Topics in Medicinal Chemistry. 4: 1347-56. PMID 15379649 DOI: 10.2174/1568026043387746  1
2004 Pinsonneault J, Nielsen CU, Sadée W. Genetic variants of the human H+/dipeptide transporter PEPT2: analysis of haplotype functions. The Journal of Pharmacology and Experimental Therapeutics. 311: 1088-96. PMID 15282265 DOI: 10.1124/jpet.104.073098  1
2004 Huang Y, Anderle P, Bussey KJ, Barbacioru C, Shankavaram U, Dai Z, Reinhold WC, Papp A, Weinstein JN, Sadée W. Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance. Cancer Research. 64: 4294-301. PMID 15205344 DOI: 10.1158/0008-5472.CAN-03-3884  1
2004 Wang D, Raehal KM, Lin ET, Lowery JJ, Kieffer BL, Bilsky EJ, Sadée W. Basal signaling activity of mu opioid receptor in mouse brain: role in narcotic dependence. The Journal of Pharmacology and Experimental Therapeutics. 308: 512-20. PMID 14600246 DOI: 10.1124/jpet.103.054049  1
2003 Pinsonneault J, Sadée W. Pharmacogenomics of multigenic diseases: sex-specific differences in disease and treatment outcome. Aaps Pharmsci. 5: E29. PMID 15198517 DOI: 10.1208/ps050429  1
2003 Phan DD, Chin-Hong P, Lin ET, Anderle P, Sadee W, Guglielmo BJ. Intra- and interindividual variabilities of valacyclovir oral bioavailability and effect of coadministration of an hPEPT1 inhibitor. Antimicrobial Agents and Chemotherapy. 47: 2351-3. PMID 12821497 DOI: 10.1128/AAC.47.7.2351-2353.2003  1
2003 Tammler U, Quillan JM, Lehmann J, Sadée W, Kassack MU. Design, synthesis, and biological evaluation of non-peptidic ligands at the Xenopus laevis skin-melanocortin receptor. European Journal of Medicinal Chemistry. 38: 481-93. PMID 12767598 DOI: 10.1016/S0223-5234(03)00062-X  1
2003 Papp AC, Pinsonneault JK, Cooke G, Sadée W. Single nucleotide polymorphism genotyping using allele-specific PCR and fluorescence melting curves. Biotechniques. 34: 1068-72. PMID 12765033  1
2003 Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, Kawamoto M, Johns SJ, DeYoung J, Carlson E, Ferrin TE, Herskowitz I, Giacomini KM. Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1. Proceedings of the National Academy of Sciences of the United States of America. 100: 5902-7. PMID 12719534 DOI: 10.1073/pnas.0730858100  1
2003 Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Urban TJ, Kroetz DL, Ferrin TE, Clark AG, Risch N, Herskowitz I, et al. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proceedings of the National Academy of Sciences of the United States of America. 100: 5896-901. PMID 12719533 DOI: 10.1073/pnas.0730857100  1
2003 Anderle P, Rakhmanova V, Woodford K, Zerangue N, Sadée W. Messenger RNA expression of transporter and ion channel genes in undifferentiated and differentiated Caco-2 cells compared to human intestines. Pharmaceutical Research. 20: 3-15. PMID 12608530 DOI: 10.1023/A:1022282221530  1
2003 Han G, Quillan JM, Carlson K, Sadée W, Hruby VJ. Design of novel chimeric melanotropin-deltorphin analogues. Discovery of the first potent human melanocortin 1 receptor antagonist. Journal of Medicinal Chemistry. 46: 810-9. PMID 12593660 DOI: 10.1021/jm020355o  1
2003 Sadee W. AAPS PharmSci: An advanced publication forum has matured Aaps Pharmsci. 5.  1
2003 Brown S, Chang JL, Sadee W, Babbitt PC. A semiautomated approach to gene discovery through expressed sequence tag data mining: Discovery of new human transporter genes Aaps Journal. 5: XI-XII.  1
2002 Lin K, Wang D, Sadée W. Serum response factor activation by muscarinic receptors via RhoA. Novel pathway specific to M1 subtype involving calmodulin, calcineurin, and Pyk2. The Journal of Biological Chemistry. 277: 40789-98. PMID 12200418 DOI: 10.1074/jbc.M202745200  1
2002 Quillan JM, Carlson KW, Song C, Wang D, Sadée W. Differential effects of mu-opioid receptor ligands on Ca(2+) signaling. The Journal of Pharmacology and Experimental Therapeutics. 302: 1002-12. PMID 12183657 DOI: 10.1124/jpet.302.3.1002  1
2002 Sadee W. Pharmacogenomics: The implementation phase Aaps Pharmsci. 4.  1
2002 Salvi A, Quillan JM, Sadee W. Monitoring intracellular pH changes in response to osmotic stress and membrane transport activity using 5-chrloromethylfluorescein Aaps Pharmsci. 4.  1
2001 Lucas JL, DeYoung JA, Sadee W. Single nucleotide polymorphisms of the human M1 muscarinic acetylcholine receptor gene Aaps Pharmsci [Electronic Resource]. 3: E31. PMID 12049494  1
2001 Sadee W, Hoeg E, Lucas J, Wang D. Genetic variations in human G protein-coupled receptors: implications for drug therapy. Aaps Pharmsci. 3: E22. PMID 11741273  1
2001 Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W. Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review Journal of the American Medical Association. 286: 2270-2279. PMID 11710893  1
2001 Wang D, Quillan JM, Winans K, Lucas JL, Sadée W. Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding. The Journal of Biological Chemistry. 276: 34624-30. PMID 11457836 DOI: 10.1074/jbc.M104083200  1
2001 Belcheva MM, Szùcs M, Wang D, Sadee W, Coscia CJ. mu-Opioid receptor-mediated ERK activation involves calmodulin-dependent epidermal growth factor receptor transactivation. The Journal of Biological Chemistry. 276: 33847-53. PMID 11457825 DOI: 10.1074/jbc.M101535200  1
2001 Wang D, Raehal KM, Bilsky EJ, Sadée W. Inverse agonists and neutral antagonists at mu opioid receptor (MOR): possible role of basal receptor signaling in narcotic dependence. Journal of Neurochemistry. 77: 1590-600. PMID 11413242 DOI: 10.1046/j.1471-4159.2001.00362.x  1
2001 Sadee W, Hoeg JLE, Wang D. Genetic variations in human G protein-coupled receptors: implications for drug therapy Aaps Journal. 3: XXVI-XXVII. DOI: 10.1208/ps030322  1
2001 Urtti A, Johns SJ, Sadee W. Genomic structure of proton-coupled oligopeptide transporter hPEPT1 and pH-sensing regulatory splice variant Aaps Pharmsci. 3.  1
2001 Graul RC, Sadee W. Evolutionary relationships among G protein-coupled receptors using a clustered database approach Aaps Pharmsci. 3.  1
2000 Phillips KA, Veenstra DL, Sadee W. Implications of the genetics revolution for health services research: pharmacogenomics and improvements in drug therapy. Health Services Research. 35: 128-40. PMID 16148957  1
2000 Yan Q, Sadée W. Human membrane transporter database: a Web-accessible relational database for drug transport studies and pharmacogenomics Aaps Pharmsci [Electronic Resource]. 2. PMID 11741236 DOI: 10.1208/ps020320  1
2000 Wang Z, Sadee W. Dissociation of morphine-induced cyclic AMP-upregulation and μ-opioid receptor desensitization Proceedings of the Western Pharmacology Society. 43: 9-10. PMID 11056942  1
2000 Burford NT, Wang D, Sadée W. G-protein coupling of mu-opioid receptors (OP3): elevated basal signalling activity. The Biochemical Journal. 348: 531-7. PMID 10839983 DOI: 10.1042/0264-6021:3480531  1
2000 Wang D, Tolbert LM, Carlson KW, Sadée W. Nuclear Ca2+/calmodulin translocation activated by mu-opioid (OP3) receptor. Journal of Neurochemistry. 74: 1418-25. PMID 10737597 DOI: 10.1046/j.1471-4159.2000.0741418.x  1
2000 Choi DS, Wang D, Tolbert L, Sadée W. Basal signaling activity of human dopamine D2L receptor demonstrated with an ecdysone-inducible mammalian expression system Journal of Neuroscience Methods. 94: 217-225. PMID 10661841 DOI: 10.1016/S0165-0270(99)00147-8  1
1999 Sadée W, Graul RC, Lee AY. Classification of membrane transporters Pharmaceutical Biotechnology. 12: 29-58. PMID 10742971 DOI: 10.1007/0-306-46812-3_2  1
1999 Surendran N, Covitz KM, Han H, Sadee W, Oh DM, Amidon GL, Williamson RM, Bigge CF, Stewart BH. Evidence for overlapping substrate specificity between large neutral amino acid (LNAA) and dipeptide (hPEPT1) transporters for PD 158473, an NMDA antagonist. Pharmaceutical Research. 16: 391-5. PMID 10213369 DOI: 10.1023/A:1018821718340  1
1999 Lin K, Sadée W, Quillan JM. Rapid measurements of intracellular calcium using a fluorescence plate reader. Biotechniques. 26: 318-22, 324-6. PMID 10023544 DOI: 10.2144/99262rr02  1
1999 Pang DC, Amidon GL, Preusch PC, Sadee W. Meeting report. Second AAPS-NIH frontier symposium 1999: Membrane transporters and drug therapy Aaps Pharmsci. 1: XI-XII. DOI: 10.1208/ps020205  1
1999 Felder CB, Graul RC, Lee AY, Merkle HP, Sadee W. The venus flytrap of periplasmic binding proteins: An ancient protein module present in multiple drug receptors Aaps Journal. 1: XIII-XIV. DOI: 10.1208/ps010202  1
1998 Burford NT, Tolbert LM, Sadee W. Specific G protein activation and mu-opioid receptor internalization caused by morphine, DAMGO and endomorphin I. European Journal of Pharmacology. 342: 123-6. PMID 9544801 DOI: 10.1016/S0014-2999(97)01556-2  1
1998 Lu YF, Xu H, Liu-Chen LY, Chen C, Partilla JS, Brine GA, Carroll FI, Rice KC, Lai J, Porreca F, Sadee W, Rothman RB. Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat mu opioid receptor. Synapse (New York, N.Y.). 28: 117-24. PMID 9450512 DOI: 10.1002/(SICI)1098-2396(199802)28:2<117::AID-SYN2>3.0.CO;2-E  1
1997 Segredo V, Burford NT, Lameh J, Sadée W. A constitutively internalizing and recycling mutant of the mu-opioid receptor. Journal of Neurochemistry. 68: 2395-404. PMID 9166733 DOI: 10.1046/j.1471-4159.1997.68062395.x  1
1997 Shockley MS, Burford NT, Sadée W, Lameh J. Residues specifically involved in down-regulation but not internalization of the m1 muscarinic acetylcholine receptor. Journal of Neurochemistry. 68: 601-9. PMID 9003046 DOI: 10.1046/j.1471-4159.1997.68020601.x  1
1996 Bilsky EJ, Inturrisi CE, Sadée W, Hruby VJ, Porreca F. Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective μ or δ opioid agonists in mice Pain. 68: 229-237. PMID 9121809 DOI: 10.1016/S0304-3959(96)03185-5  1
1996 Covitz KMY, Amidon GL, Sadée W. Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells Pharmaceutical Research. 13: 1631-1634. PMID 8956326 DOI: 10.1023/A:1016476220296  1
1995 Sadée W, Drübbisch V, Amidon GL. Biology of Membrane Transport Proteins Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 12: 1823-1837. PMID 8786953 DOI: 10.1023/A:1016211015926  1
1994 Wang Z, Bilsky EJ, Porreca F, Sadée W. Accelerated communciation: Constitutive μ opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence Life Sciences. 54. DOI: 10.1016/0024-3205(94)90022-1  1
1992 Cook JS, Wolsing DH, Lameh J, Olson CA, Correa PE, Sadee W, Blumenthal EM, Rosenbaum JS. Characterization of the RDC1 gene which encodes the canine homolog of a proposed human VIP receptor. Expression does not correlate with an increase in VIP binding sites. Febs Letters. 300: 149-52. PMID 1373390 DOI: 10.1016/0014-5793(92)80184-I  1
1990 Duan DS, Farmer D, Rayner AA, Sadee W. Cytotoxicity of lymphokine-activated killer cells against human neuroblastoma cells: Modulation by neuroblast differentiation Medical and Pediatric Oncology. 18: 339-344. PMID 1972538 DOI: 10.1002/mpo.2950180418  1
1989 Waschek JA, Muller JM, Duan DS, Sadée W. Retinoic acid enhances VIP receptor expression and responsiveness in human neuroblastoma cell, SH-SY5Y. Febs Letters. 250: 611-4. PMID 2546814 DOI: 10.1016/0014-5793(89)80806-3  1
1988 Hochhaus G, Sadée W. A Biotin–Avidin-Based Enzyme Immunoassay for βh-Endorphin Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 5: 232-235. PMID 2977649 DOI: 10.1023/A:1015993713471  1
1988 Hochhaus G, Patthy A, Schwietert R, Santi DV, Sadée W. [Biocytin13]Dynorphin A 1-13 Amide: A Potential Probe for the κ-Opioid Receptor Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 5: 790-794. PMID 2907785 DOI: 10.1023/A:1015944903360  1
1988 Yu VC, Hochhaus G, Chang FH, Richards ML, Bourne HR, Sadée W. Differentiation of human neuroblastoma cells: marked potentiation of prostaglandin E-stimulated accumulation of cyclic AMP by retinoic acid. Journal of Neurochemistry. 51: 1892-9. PMID 2903224 DOI: 10.1111/j.1471-4159.1988.tb01174.x  1
1988 Sadee W, Yu VC, Hochhaus G. Effects of opioid peptides on human neuroblastoma cells Nida Research Monograph Series. 111-117. PMID 2855093  1
1988 Preis PN, Saya H, Nadasdi L, Hochhaus G, Levin V, Sadee W. Neuronal Cell Differentiation of Human Neuroblastoma Cells by Retinoic Acid plus Herbimycin A Cancer Research. 48: 6530-6534. PMID 2846152  1
1988 Hochhaus G, Gibson BW, Sadee W. Biotinylated human β-endorphins as probes for the opioid receptor Journal of Biological Chemistry. 263: 92-97. PMID 2826453  1
1986 Lybrand TP, Kollman PA, Yu VC, Sadée W. Conformation and electrostatic potential surfaces of opiates: Relationship to µ- and λ-site binding. Pharmaceutical Research. 3: 218-24. PMID 24271585 DOI: 10.1023/A:1016338730077  1
1986 Day JL, Sadee W. Determination of 5-fluorouridine diphosphate glucose as a metabolite of 5-fluorouracil in mouse T-lymphoma (S-49) cells using high-performance liquid chromatography. Journal of Chromatography. 356: 445-9. PMID 3486874 DOI: 10.1016/S0021-9673(00)91515-2  1
1986 Hochhaus G, Yu VC, Sadée W. Delta opioid receptor in human neuroblastoma cell lines Brain Research. 382: 327-331. PMID 3019481 DOI: 10.1016/0006-8993(86)91341-7  1
1986 Hochhaus G, Gibson BW, Sadée W. Development of a biotin-avidin probe for detecting opioid receptors Nida Research Monograph. 75: 33-36. PMID 2828982  1
1986 Nguyen BT, Sadee W. Compartmentation of guanine nucleotide precursors for DNA synthesis Biochemical Journal. 234: 263-269. PMID 2424429 DOI: 10.1042/bj2340263  1
1985 Sadée W, Nguyen BT. Biological consequences of guanine starvation Basic Life Sciences. 31: 233-240. PMID 3922344 DOI: 10.1007/978-1-4613-2449-2_14  1
1984 Yu VC, Jacobson AE, Rice KC, Sadée W. Stereospecificity of 4,5-epoxymorphinan binding to the λ site in rat brain European Journal of Pharmacology. 101: 161-162. PMID 6086361 DOI: 10.1016/0014-2999(84)90045-1  1
1981 Day JL, Maybaum J, Sadée W. Determination of 5-fluoro-2'-deoxyuridine[6-3H] as an impurity in 5-fluoro-uracil[6-3H] by high-performance liquid chromatography. Journal of Chromatography. 206: 407-9. PMID 6453879 DOI: 10.1016/S0021-9673(00)82557-1  1
1978 Marques RA, Stafford B, Flynn N, Sadée W. Determination of metronidazole and misonidazole and their metabolites in plasma and urine by high-performance liquid chromatography Journal of Chromatography B: Biomedical Sciences and Applications. 146: 163-166. PMID 670352 DOI: 10.1016/S0378-4347(00)81303-1  1
1972 Castagnoli N, Sadée W. Mechanism of the reaction of a 1,4-benzodiazepine N-oxide with acetic anhydride. Journal of Medicinal Chemistry. 15: 1076-8. PMID 5069778  1
1972 Sadée W, Riegelman S, Jones SC. Disposition of tritium-labeled spirolactones in the dog Journal of Pharmaceutical Sciences. 61: 1132-1135. PMID 5044816 DOI: 10.1002/jps.2600610721  1
1972 Sadée W, Riegelman S, Jones SC. Plasma levels of spirolactones in the dog Journal of Pharmaceutical Sciences. 61: 1129-1132. PMID 5044815 DOI: 10.1002/jps.2600610720  1
1971 Sadèe W, Garland W, Castagnoli N. Microsomal 3-hydroxylation of 1,4-benzodiazepines. Journal of Medicinal Chemistry. 14: 643-5. PMID 5164455  1
1971 Sadée W, Riegelman S, Johnson LF. On the mechanism of steroid fluorescence in sulfuric acid. Part I. The formation of trienones Steroids. 17: 595-606. PMID 5088146 DOI: 10.1016/S0039-128X(71)80160-5  1
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