Richard D. Leapman - Publications

Affiliations: 
NIH (NIBIB) 

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Year Citation  Score
2020 Rao A, McBride EL, Zhang G, Xu H, Cai T, Notkins AL, Aronova MA, Leapman RD. Determination of secretory granule maturation times in pancreatic islet β-cells by serial block face scanning electron microscopy. Journal of Structural Biology. 107584. PMID 32736074 DOI: 10.1016/J.Jsb.2020.107584  0.315
2020 Fera A, He Q, Zhang G, Leapman RD. Quantitative method for estimating stain density in electron microscopy of conventionally prepared biological specimens. Journal of Microscopy. 277: 71-78. PMID 31994199 DOI: 10.1111/Jmi.12865  0.378
2020 Aronova MA, Noh S, Byrnes C, Zhang G, Kim Y, Meier ER, Leapman RD. Quantitative Imaging with Electron Probes of Cultured Erythroblasts Undergoing Erythropoiesis Biophysical Journal. 118: 293a-294a. DOI: 10.1016/J.Bpj.2019.11.1665  0.339
2020 Guay MD, Cheng R, Emam ZA, Leapman RD. Neural Modeling of Eukaryotic Cell Ultrastructure Obtained from 3D Electron Microscopy Biophysical Journal. 118: 293a. DOI: 10.1016/J.Bpj.2019.11.1663  0.341
2019 Leapman R, Aronova M, Rao A, McBride E, Zhang G, Xu H, Notkins A, Cai T. Maturation Times of Pancreatic Beta Cell Secretory Granules Estimated from Serial Block-Face Electron Microscopy Microscopy and Microanalysis. 25: 1380-1381. DOI: 10.1017/S1431927619007633  0.31
2019 Ling K, Vedanaparti Y, Tobin MP, Desai RP, Zhang G, Pokrovskaya ID, Storrie B, Aronova MA, Leapman RD. Structural Analysis of Mouse Platelets using Serial Block-Face Scanning Electron Microscopy Biophysical Journal. 116: 573a. DOI: 10.1016/J.Bpj.2018.11.3082  0.351
2019 Guay MD, Emam ZA, Anderson AB, Leapman RD. Transfer Learning for Efficient Segmentation of Subcellular Structures in 3-D Electron Microscopy Biophysical Journal. 116: 288a. DOI: 10.1016/J.Bpj.2018.11.1554  0.303
2018 Chen X, Winters C, Crocker V, Lazarou M, Sousa AA, Leapman RD, Reese TS. Identification of PSD-95 in the Postsynaptic Density Using MiniSOG and EM Tomography. Frontiers in Neuroanatomy. 12: 107. PMID 30581381 DOI: 10.3389/Fnana.2018.00107  0.324
2018 He Q, Hsueh M, Zhang G, Joy DC, Leapman RD. Biological serial block face scanning electron microscopy at improved z-resolution based on Monte Carlo model. Scientific Reports. 8: 12985. PMID 30154532 DOI: 10.1038/S41598-018-31231-W  0.409
2018 McBride EL, Rao A, Zhang G, Hoyne JD, Calco GN, Kuo BC, He Q, Prince AA, Pokrovskaya ID, Storrie B, Sousa AA, Aronova MA, Leapman RD. Comparison of 3D cellular imaging techniques based on scanned electron probes: serial block face SEM vs. axial bright-field STEM tomography. Journal of Structural Biology. PMID 29408702 DOI: 10.1016/J.Jsb.2018.01.012  0.394
2018 Guay M, Emam Z, Leapman R. Problems and Progress in Automating Electron Microscopy Segmentation Microscopy and Microanalysis. 24: 508-509. DOI: 10.1017/S1431927618003033  0.314
2018 Aronova M, Chen S, Lai B, Pivovarova N, Daoust A, Andrews S, Koretsky A, Leapman R. Correlative Bioimaging with Electron, X-ray and Light Microscopies Microscopy and Microanalysis. 24: 374-375. DOI: 10.1017/S1431927618002362  0.306
2018 He Q, Joy DC, Zhang G, Leapman RD. Dual-Energy Serial Block Face SEM Imaging of Biological Structures at Near Isotropic Spatial Resolution Biophysical Journal. 114: 160a-161a. DOI: 10.1016/J.Bpj.2017.11.899  0.311
2018 Leapman RD, Aronova MA, Rao A, McBride EL, Zhang G, Xu H, Notkins AL, Cai T. Quantitative Analysis of Immature Secretory Granules in Beta Cells of Mouse Pancreatic Islets by Serial Block-Face Scanning Electron Microscopy Biophysical Journal. 114: 370a. DOI: 10.1016/J.Bpj.2017.11.2050  0.342
2017 Leapman RD. Application of EELS and EFTEM to the life sciences enabled by the contributions of Ondrej Krivanek. Ultramicroscopy. PMID 28258873 DOI: 10.1016/J.Ultramic.2017.01.002  0.369
2017 Leapman R, McBride E, Rao A, Zhang G, He Q, Guay M, Pokrovskaya I, Storrie B, Aronova M. Comparison of 3-D Cellular Imaging Techniques using Scanned Electron Probes Microscopy and Microanalysis. 23: 1150-1151. DOI: 10.1017/S1431927617006419  0.363
2017 McBride EL, Rao A, Zhang G, Pokrovskaya ID, Aronova MA, Storrie B, Leapman RD. Comparison of 3-D Cell and Tissue Imaging Techniques Based on Scanning Electron Probes Biophysical Journal. 112: 574a. DOI: 10.1016/J.Bpj.2016.11.3090  0.416
2016 Guay MD, Czaja W, Aronova MA, Leapman RD. Compressed Sensing Electron Tomography for Determining Biological Structure. Scientific Reports. 6: 27614. PMID 27291259 DOI: 10.1038/Srep27614  0.346
2016 Aronova MA, Sousa AA, Leapman RD. Quantitative Characterization of Theranostic Nanoparticles by Electron Microscopy Microscopy and Microanalysis. 22: 1154-1155. DOI: 10.1017/S1431927616006619  0.336
2016 He Q, Aronova MA, Joy DC, Zhang G, Leapman RD. Serial Block Face Sem of Biological Structures at Near Isotropic Spatial Resolution using Multiple Beam Energies and Monte Carlo Simulations Biophysical Journal. 110: 158a-159a. DOI: 10.1016/J.Bpj.2015.11.889  0.381
2016 Calco GN, Kuo BC, Hoyne JD, Aronova MA, Zhang G, Leapman RD. Mitochondrial Networks in Beta Cells of Pancreatic Islet of Langerhans Investigated by Serial Block Face Scanning Electron Microscopy Biophysical Journal. 110: 156a. DOI: 10.1016/J.Bpj.2015.11.877  0.311
2015 Chen RJ, Zhang G, Garfield SH, Shi YJ, Chen KG, Robey PG, Leapman RD. Variations in Glycogen Synthesis in Human Pluripotent Stem Cells with Altered Pluripotent States. Plos One. 10: e0142554. PMID 26565809 DOI: 10.1371/Journal.Pone.0142554  0.477
2015 Shomorony A, Pfeifer CR, Aronova MA, Zhang G, Cai T, Xu H, Notkins AL, Leapman RD. Combining quantitative 2D and 3D image analysis in the serial block face SEM: application to secretory organelles of pancreatic islet cells. Journal of Microscopy. PMID 26139222 DOI: 10.1111/Jmi.12276  0.316
2015 He Q, Aronova MA, Joy DC, Zhang G, Leapman RD. Sub-Surface Serial Block Face Scanning Electron Microscopy Biophysical Journal. 108: 619a-620a. DOI: 10.1016/J.Bpj.2014.11.3371  0.389
2015 Hoyne JD, Calco GN, Kuo BC, Aronova MA, Sousa AA, He Q, Zhang G, Pokrovskaya ID, MacDonald L, Prince AA, Storrie B, Leapman RD. Scanning Transmission Electron Tomography of Blood Platelets in Thick Sections Biophysical Journal. 108: 618a. DOI: 10.1016/J.Bpj.2014.11.3362  0.372
2015 Calco GN, Hoyne JD, Kuo BC, Aronova MA, Zhang G, Shomorony A, Pfeifer CR, Cai T, Xu H, Notkins AL, Leapman RD. 3D Ultrastructural Investigation of Entire Pancreatic Islets of Langerhans by Serial Block Face Scanning Electron Microscopy Biophysical Journal. 108: 190a. DOI: 10.1016/J.Bpj.2014.11.1053  0.332
2014 Trachtenberg S, Schuck P, Phillips TM, Andrews SB, Leapman RD. A structural framework for a near-minimal form of life: Mass and compositional analysis of the helical mollicute Spiroplasma melliferum BC3 Plos One. 9. PMID 24586297 DOI: 10.1371/Journal.Pone.0087921  0.329
2014 Pfeifer CR, Shomorony A, Zhang G, Aronova MA, Leapman RD. Serial Block-Face Scanning Electron Microscopy for Nanoscale Characterization of Tissue Ultrastructure Biophysical Journal. 106: 601a. DOI: 10.1016/J.Bpj.2013.11.3327  0.407
2014 Guay MD, Czaja W, Leapman RD. Compressed Sensing Methods for Electron Tomography of Cellular Structure Biophysical Journal. 106: 598a-599a. DOI: 10.1016/J.Bpj.2013.11.3314  0.343
2013 Aronova MA, Leapman RD. Elemental mapping by electron energy loss spectroscopy in biology. Methods in Molecular Biology (Clifton, N.J.). 950: 209-26. PMID 23086878 DOI: 10.1007/978-1-62703-137-0_13  0.391
2013 Sousa AA, Leapman RD. Mass mapping of amyloid fibrils in the electron microscope using STEM imaging. Methods in Molecular Biology (Clifton, N.J.). 950: 195-207. PMID 23086877 DOI: 10.1007/978-1-62703-137-0_12  0.351
2013 Bhirde AA, Jin AJ, Thompson CN, Ramiro I, Milstone ZJ, Sousa AA, Smith PD, Gutkind JS, Leapman RD, Sun Y, Chen X. Variable Cellular Conduct of Photonic Carbon Nano-Dots Biophysical Journal. 104: 514a. DOI: 10.1016/J.Bpj.2012.11.2841  0.304
2013 Sousa AA, Zhang J, Chen X, Reese TS, Diamond JS, Leapman RD. Three-Dimensional Visualization of Whole Synapses by Stem Tomography Biophysical Journal. 104: 353a. DOI: 10.1016/J.Bpj.2012.11.1960  0.35
2012 Aronova MA, Leapman RD. Development of Electron Energy Loss Spectroscopy in the Biological Sciences. Mrs Bulletin / Materials Research Society. 37: 53-62. PMID 23049161 DOI: 10.1557/Mrs.2011.329  0.413
2012 Sousa AA, Leapman RD. Development and application of STEM for the biological sciences. Ultramicroscopy. 123: 38-49. PMID 22749213 DOI: 10.1016/J.Ultramic.2012.04.005  0.409
2012 Fera A, Dosemeci A, Sousa AA, Yang C, Leapman RD, Reese TS. Direct visualization of CaMKII at postsynaptic densities by electron microscopy tomography. The Journal of Comparative Neurology. 520: 4218-25. PMID 22627922 DOI: 10.1002/Cne.23151  0.313
2012 Sousa AA, Morgan JT, Brown PH, Adams A, Jayasekara MP, Zhang G, Ackerson CJ, Kruhlak MJ, Leapman RD. Synthesis, characterization, and direct intracellular imaging of ultrasmall and uniform glutathione-coated gold nanoparticles. Small (Weinheim An Der Bergstrasse, Germany). 8: 2277-86. PMID 22517616 DOI: 10.1002/Smll.201200071  0.316
2012 Sousa AA, Winters CA, Cox D, Chen X, Reese TS, Leapman RD. Three-Dimensional Ultrastructure of Micrometer Thick Cellular Subvolumes by STEM Tomography Biophysical Journal. 102: 393a. DOI: 10.1016/J.Bpj.2011.11.2146  0.39
2011 Sousa AA, Azari AA, Zhang G, Leapman RD. Dual-axis electron tomography of biological specimens: Extending the limits of specimen thickness with bright-field STEM imaging. Journal of Structural Biology. 174: 107-14. PMID 21055473 DOI: 10.1016/J.Jsb.2010.10.017  0.394
2011 Leapman R, Aronova M, Cox D, Adams A, Zhang G, Sousa A. Imaging Cells and Bionanoparticles by STEM and EFTEM Tomography Microscopy and Microanalysis. 17: 972-973. DOI: 10.1017/S1431927611005733  0.322
2010 Aronova MA, Sousa AA, Zhang G, Leapman RD. Limitations of beam damage in electron spectroscopic tomography of embedded cells. Journal of Microscopy. 239: 223-32. PMID 20701660 DOI: 10.1111/J.1365-2818.2010.03376.X  0.373
2010 Leapman RD. Nanoparticles: Dissected with electrons. Nature Nanotechnology. 5: 480-1. PMID 20606638 DOI: 10.1038/Nnano.2010.131  0.359
2010 Aronova M, Sousa A, Leapman R. Investigation of Radiolytic Effects in Frozen Aqueous Specimens by Electron Energy Loss Spectroscopy Microscopy and Microanalysis. 16: 1542-1543. DOI: 10.1017/S1431927610062884  0.364
2009 Bhirde AA, Sousa AA, Patel V, Azari AA, Gutkind JS, Leapman RD, Rusling JF. Imaging the distribution of individual platinum-based anticancer drug molecules attached to single-wall carbon nanotubes. Nanomedicine (London, England). 4: 763-72. PMID 19839812 DOI: 10.2217/Nnm.09.56  0.32
2009 Hohmann-Marriott MF, Sousa AA, Azari AA, Glushakova S, Zhang G, Zimmerberg J, Leapman RD. Nanoscale 3D cellular imaging by axial scanning transmission electron tomography. Nature Methods. 6: 729-31. PMID 19718033 DOI: 10.1038/Nmeth.1367  0.394
2009 Chen KG, Leapman RD, Zhang G, Lai B, Valencia JC, Cardarelli CO, Vieira WD, Hearing VJ, Gottesman MM. Influence of melanosome dynamics on melanoma drug sensitivity. Journal of the National Cancer Institute. 101: 1259-71. PMID 19704071 DOI: 10.1093/Jnci/Djp259  0.466
2009 Sousa AA, Aronova MA, Wu H, Sarin H, Griffiths G, Leapman RD. Determining molecular mass distributions and compositions of functionalized dendrimer nanoparticles. Nanomedicine (London, England). 4: 391-9. PMID 19505242 DOI: 10.2217/Nnm.09.14  0.35
2009 Aronova MA, Kim YC, Pivovarova NB, Andrews SB, Leapman RD. Quantitative EFTEM mapping of near physiological calcium concentrations in biological specimens. Ultramicroscopy. 109: 201-12. PMID 19118952 DOI: 10.1016/J.Ultramic.2008.10.003  0.348
2009 Sousa AA, Hohmann-Marriott MF, Zhang G, Leapman RD. Monte Carlo electron-trajectory simulations in bright-field and dark-field STEM: implications for tomography of thick biological sections. Ultramicroscopy. 109: 213-21. PMID 19110374 DOI: 10.1016/J.Ultramic.2008.10.005  0.374
2009 Aronova MA, Kim Y, Sousa AA, Zhang G, Leapman RD. New Approach To Quantitative Subcellular Imaging Of Phosphorus And Calcium Using Energy-filtered Transmission Electron Microscopy And Tomography Biophysical Journal. 96: 640a. DOI: 10.1016/J.Bpj.2008.12.3385  0.425
2008 Sousa AA, Hohmann-Marriott M, Aronova MA, Zhang G, Leapman RD. Determination of quantitative distributions of heavy-metal stain in biological specimens by annular dark-field STEM. Journal of Structural Biology. 162: 14-28. PMID 18359249 DOI: 10.1016/J.Jsb.2008.01.007  0.328
2008 Sousa AA, Aronova MA, Kim YC, Dorward LM, Zhang G, Leapman RD. Reprint of "On the feasibility of visualizing ultrasmall gold labels in biological specimens by STEM tomography" [J. Struct. Biol. 159 (2007) 507-522]. Journal of Structural Biology. 161: 336-51. PMID 18342743 DOI: 10.1016/S1047-8477(08)00063-4  0.356
2008 Aronova MA, Kim YC, Harmon R, Sousa AA, Zhang G, Leapman RD. Reprint of "Three-dimensional elemental mapping of phosphorus by quantitative electron spectroscopic tomography (QuEST)" [J. Struct. Biol. 160 (2007) 35-48]. Journal of Structural Biology. 161: 322-35. PMID 18342742 DOI: 10.1016/S1047-8477(08)00062-2  0.381
2007 Luca S, Yau WM, Leapman R, Tycko R. Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR. Biochemistry. 46: 13505-22. PMID 17979302 DOI: 10.1021/Bi701427Q  0.312
2007 Sousa AA, Leapman RD. Quantitative STEM mass measurement of biological macromolecules in a 300 kV TEM. Journal of Microscopy. 228: 25-33. PMID 17910694 DOI: 10.1111/J.1365-2818.2007.01819.X  0.359
2007 Aronova MA, Kim YC, Harmon R, Sousa AA, Zhang G, Leapman RD. Three-dimensional elemental mapping of phosphorus by quantitative electron spectroscopic tomography (QuEST). Journal of Structural Biology. 160: 35-48. PMID 17693097 DOI: 10.1016/J.Jsb.2007.06.008  0.381
2007 Sousa AA, Aronova MA, Kim YC, Dorward LM, Zhang G, Leapman RD. On the feasibility of visualizing ultrasmall gold labels in biological specimens by STEM tomography. Journal of Structural Biology. 159: 507-22. PMID 17689263 DOI: 10.1016/J.Jsb.2007.06.006  0.356
2007 Leapman RD, Aronova MA. Localizing specific elements bound to macromolecules by EFTEM. Methods in Cell Biology. 79: 593-613. PMID 17327176 DOI: 10.1016/S0091-679X(06)79024-0  0.383
2007 Aronova MA, Kim YC, Zhang G, Leapman RD. Quantification and thickness correction of EFTEM phosphorus maps. Ultramicroscopy. 107: 232-44. PMID 16979822 DOI: 10.1016/J.Ultramic.2006.07.009  0.343
2007 Leapman R, Aronova M. Progress in Electron Energy Loss Spectroscopy, Elemental Mapping and Elemental Tomography of Biological Structures Microscopy and Microanalysis. 13. DOI: 10.1017/S1431927607078762  0.35
2007 Aronova M, Kim Y, Harmon R, Sousa A, Zhang G, Leapman R. Elemental Mapping of Phosphorus in 3-D by Quantitative Electron Spectroscopic Tomography Microscopy and Microanalysis. 13. DOI: 10.1017/S1431927607076969  0.331
2007 Booth C, Harmon R, Meyer S, Twesten R, Arslan I, Bradley J, Aronova M, Leapman R, Hunt J. Moving Beyond Bright Field Transmission Electron Microscopy Microscopy and Microanalysis. 13. DOI: 10.1017/S1431927607076957  0.341
2006 Chen KG, Valencia JC, Lai B, Zhang G, Paterson JK, Rouzaud F, Berens W, Wincovitch SM, Garfield SH, Leapman RD, Hearing VJ, Gottesman MM. Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas. Proceedings of the National Academy of Sciences of the United States of America. 103: 9903-7. PMID 16777967 DOI: 10.1073/Pnas.0600213103  0.443
2004 Leapman RD. Novel techniques in electron microscopy. Current Opinion in Neurobiology. 14: 591-8. PMID 15464893 DOI: 10.1016/J.Conb.2004.08.004  0.412
2004 Leapman RD, Kocsis E, Zhang G, Talbot TL, Laquerriere P. Three-dimensional distributions of elements in biological samples by energy-filtered electron tomography. Ultramicroscopy. 100: 115-25. PMID 15219696 DOI: 10.1016/J.Ultramic.2004.03.002  0.383
2004 Kajava AV, Potekhin SA, Corradin G, Leapman RD. Organization of designed nanofibrils assembled from alpha-helical peptides as determined by electron microscopy. Journal of Peptide Science : An Official Publication of the European Peptide Society. 10: 291-7. PMID 15160841 DOI: 10.1002/Psc.520  0.329
2003 Goping G, Pollard HB, Srivastava M, Leapman R. Mapping protein expression in mouse pancreatic islets by immunolabeling and electron energy loss spectrum-imaging Microscopy Research and Technique. 61: 448-456. PMID 12845571 DOI: 10.1002/Jemt.10294  0.303
2003 Leapman RD. Detecting single atoms of calcium and iron in biological structures by electron energy-loss spectrum-imaging. Journal of Microscopy. 210: 5-15. PMID 12694411 DOI: 10.1046/J.1365-2818.2003.01173.X  0.394
2003 Trachtenberg S, Andrews SB, Leapman RD. Mass distribution and spatial organization of the linear bacterial motor of Spiroplasma citri R8A2. Journal of Bacteriology. 185: 1987-94. PMID 12618463 DOI: 10.1128/Jb.185.6.1987-1994.2003  0.324
2003 Levin I, Leapman RD, Kovler M, Roizin Y. Radiation-induced nitrogen segregation during electron energy loss spectroscopy of silicon oxide-nitride-oxide stacks Applied Physics Letters. 83: 1548-1550. DOI: 10.1063/1.1604182  0.303
2003 Leapman RD, Andrews SB. Detection limits for electron energy-loss spectroscopy in biology Microscopy and Microanalysis. 9: 1476-1477. DOI: 10.1017/S1431927603447387  0.353
2000 Andrews SB, Hongpaisan J, Pivovarova NB, Friel DD, Leapman RD. Mapping the Subcellular Distribution of Calcium in Depolarized Neurons by Electron Energy Loss Spectrum Imaging Microscopy and Microanalysis. 6: 162-163. DOI: 10.1017/S1431927600033304  0.338
2000 Leapman RD, Brooks CM, Rizzo NW, Talbot TL. Quantitative Analysis Of Bological Specimens by Spectrum-Imaging in the Energy Filtering Transmission Electron Microscope Microscopy and Microanalysis. 6: 160-161. DOI: 10.1017/S1431927600033298  0.356
1999 Leapman RD, Rizzo NW. Towards single atom analysis of biological structures. Ultramicroscopy. 78: 251-68. PMID 10389278 DOI: 10.1016/S0304-3991(99)00031-5  0.377
1999 Levin I, Leapman RD, Kaiser DL, Van Buskirk PC, Bilodeau S, Carl R. Accommodation of excess Ti in a (Ba,Sr)TiO3 thin film with 53.4% Ti grown on Pt/Sio2/Si by metalorganic chemical-vapor deposition Applied Physics Letters. 75: 1299-1301. DOI: 10.1063/1.124674  0.301
1997 Leapman RD, Jarnik M, Steven AC. Spatial distributions of sulfur-rich proteins in cornifying epithelia. Journal of Structural Biology. 120: 168-79. PMID 9417981 DOI: 10.1006/Jsbi.1997.3937  0.36
1997 Scott DA, Docampo R, Dvorak JA, Shi S, Leapman RD. In situ compositional analysis of acidocalcisomes in Trypanosoma cruzi. The Journal of Biological Chemistry. 272: 28020-9. PMID 9346954 DOI: 10.1074/Jbc.272.44.28020  0.374
1997 Leapman RD, Gallant PE, Reese TS, Andrews SB. Phosphorylation and subunit organization of axonal neurofilaments determined by scanning transmission electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 94: 7820-4. PMID 9223270 DOI: 10.1073/Pnas.94.15.7820  0.365
1997 Morris MD, Leapman RD. Book Reviews: Modern Techniques in Raman Spectroscopy, Electron Energy-Loss Spectroscopy in the Electron Microscope Applied Spectroscopy. 51: 76A-78A. DOI: 10.1366/0003702971940062  0.367
1997 Rightor EG, Hitchcock AP, Ade H, Leapman RD, Urquhart SG, Smith AP, Mitchell G, Fischer D, Shin HJ, Warwick T. Spectromicroscopy of poly(ethylene terephthalate): Comparison of spectra and radiation damage rates in X-ray absorption and electron energy loss Journal of Physical Chemistry B. 101: 1950-1960. DOI: 10.1021/Jp9622748  0.348
1996 Shi S, Sun S, Andrews SB, Leapman RD. Thickness measurement of hydrated and dehydrated cryosections by EELS. Microscopy Research and Technique. 33: 241-50. PMID 8652882 DOI: 10.1002/(Sici)1097-0029(19960215)33:3<241::Aid-Jemt1>3.0.Co;2-T  0.385
1995 Leapman RD, Sun S. Cryo-electron energy loss spectroscopy: observations on vitrified hydrated specimens and radiation damage. Ultramicroscopy. 59: 71-9. PMID 7571121 DOI: 10.1016/0304-3991(95)00019-W  0.343
1995 Hunt JA, Disko MM, Behal SK, Leapman RD. Electron energy-loss chemical imaging of polymer phases Ultramicroscopy. 58: 55-64. DOI: 10.1016/0304-3991(94)00178-P  0.342
1994 Leapman RD, Sun SQ, Hunt JA, Andrews SB. Biological electron energy loss spectroscopy in the field-emission scanning transmission electron microscope. Scanning Microscopy. Supplement. 8: 245-58; discussion 2. PMID 7638490  0.309
1994 Leapman R, Sun S, Hunt J, Andrews S. Eels Imaging of Biological Materials Mrs Proceedings. 332. DOI: 10.1557/Proc-332-351  0.413
1994 Newbury DE, Leapman RD. Trace Analysis of Nanoscale Materials by Analytical Electron Microscopy Mrs Proceedings. 332. DOI: 10.1557/Proc-332-287  0.36
1993 Leapman RD, Hunt JA, Buchanan RA, Andrews SB. Measurement of low calcium concentrations in cryosectioned cells by parallel-EELS mapping. Ultramicroscopy. 49: 225-34. PMID 8475601 DOI: 10.1016/0304-3991(93)90229-Q  0.377
1993 Ciliax BJ, Kirk KL, Leapman RD. Radiation damage of fluorinated organic compounds measured by parallel electron energy loss spectroscopy. Ultramicroscopy. 48: 13-25. PMID 8438530 DOI: 10.1016/0304-3991(93)90167-V  0.303
1993 Buchanan RA, Leapman RD, O'Connell MF, Reese TS, Andrews SB. Quantitative scanning transmission electron microscopy of ultrathin cryosections: subcellular organelles in rapidly frozen liver and cerebellar cortex. Journal of Structural Biology. 110: 244-55. PMID 8373705 DOI: 10.1006/Jsbi.1993.1027  0.366
1993 Sun S, Shi S, Leapman R. Water distributions of hydrated biological specimens by valence electron energy loss spectroscopy. Ultramicroscopy. 50: 127-39. PMID 8367908 DOI: 10.1016/0304-3991(93)90003-G  0.354
1993 Leapman RD, Brink J, Chiu W. Low-dose thickness measurement of glucose-embedded protein crystals by electron energy loss spectroscopy and STEM dark-field imaging. Ultramicroscopy. 52: 157-66. PMID 8291165 DOI: 10.1016/0304-3991(93)90186-2  0.314
1993 Leapman RD, Newbury DE. Trace elemental analysis at nanometer spatial resolution by parallel-detection electron energy loss spectroscopy. Analytical Chemistry. 65: 2409-14. PMID 8238934 DOI: 10.1021/Ac00066A003  0.376
1992 Leapman R. Acquisition and data processing in biological electron energy loss spectroscopy. Ultramicroscopy. 38: 361-2. PMID 1785144 DOI: 10.1016/0304-3991(91)90171-2  0.346
1992 Leapman RD, Andrews SB. Characterization of biological macromolecules by combined mass mapping and electron energy-loss spectroscopy. Journal of Microscopy. 165: 225-38. PMID 1564721 DOI: 10.1111/J.1365-2818.1992.Tb01482.X  0.382
1991 Leapman RD, Andrews SB. Analysis of directly frozen macromolecules and tissues in the field-emission STEM. Journal of Microscopy. 161: 3-19. PMID 2016736 DOI: 10.1111/J.1365-2818.1991.Tb03070.X  0.409
1991 Leapman RD, Brian Andrews S. Biological electron energy loss spectroscopy: the present and the future Microscopy Microanalysis Microstructures. 2: 387-394. DOI: 10.1051/Mmm:0199100202-3038700  0.394
1991 Leapman RD, Hunt JA. Comparison of detection limits for EELS and EDXS Microscopy Microanalysis Microstructures. 2: 231-244. DOI: 10.1051/Mmm:0199100202-3023100  0.345
1989 Leapman R. Problems in Electron Energy Loss Spectroscopy Ultramicroscopy. 28: 74-75. DOI: 10.1016/0304-3991(89)90274-X  0.333
1988 Leapman RD, Ornberg RL. Quantitative electron energy loss spectroscopy in biology. Ultramicroscopy. 24: 251-68. PMID 3281358 DOI: 10.1016/0304-3991(88)90314-2  0.365
1988 Leapman RD, Swyt CR. Separation of overlapping core edges in electron energy loss spectra by multiple-least-squares fitting. Ultramicroscopy. 26: 393-403. PMID 3238813 DOI: 10.1016/0304-3991(88)90239-2  0.337
1987 Leapman RD, Fiori CE, Gorlen KE. Elemental imaging by EELS and EDXS in the analytical electron microscope : Its relevance to trace element research. Biological Trace Element Research. 13: 89-102. PMID 24254668 DOI: 10.1007/Bf02796624  0.396
1986 Leapman RD. Scanning transmission electron microscope (STEM) elemental mapping by electron energy-loss spectroscopy. Annals of the New York Academy of Sciences. 483: 326-38. PMID 3551725 DOI: 10.1111/J.1749-6632.1986.Tb34539.X  0.396
1986 Leapman R. Section II: Electron energy loss spectroscopy Journal of Electron Microscopy Technique. 4: 95-102. DOI: 10.1002/Jemt.1060040204  0.335
1984 Leapman RD, Fiori CE, Swyt CR. Mass thickness determination by electron energy loss for quantitative X-ray microanalysis in biology Journal of Microscopy. 133: Pt 3/-. PMID 6716460 DOI: 10.1111/J.1365-2818.1984.Tb00489.X  0.332
1984 Gorlen KE, Barden LK, Del Priore JS, Fiori CE, Gibson CC, Leapman RD. Computerized analytical electron microscope for elemental imaging Review of Scientific Instruments. 55: 912-921. DOI: 10.1063/1.1137864  0.381
1983 Leapman RD, Fejes PL, Silcox J. Orientation dependence of core edges from anisotropic materials determined by inelastic scattering of fast electrons Physical Review B. 28: 2361-2373. DOI: 10.1103/Physrevb.28.2361  0.301
1983 Leapman RD, Fiori CE, Gorlen KE, Gibson CC, Swyt CR. Combined elemental and stem imaging under computer control Ultramicroscopy. 12: 281-291. DOI: 10.1016/0304-3991(83)90242-5  0.373
1982 Grunes LA, Leapman RD, Wilker CN, Hoffmann R, Kunz AB. Oxygen K near-edge fine structure: An electron-energy-loss investigation with comparisons to new theory for selected 3d transition-metal oxides Physical Review B. 25: 7157-7173. DOI: 10.1103/Physrevb.25.7157  0.306
1979 Leapman RD, Silcox J. Orientation dependence of core edges in electron-energy-loss spectra from anisotropic materials Physical Review Letters. 42: 1361-1364. DOI: 10.1103/Physrevlett.42.1361  0.332
1978 Leapman RD, Sanderson SJ, Whelan MJ. APPLICATION OF ELECTRON ENERGY LOSS SPECTROMETRY TO PRECIPITATE MICROANALYSIS IN 9%Cr-1% Mo STEEL Met Sci. 21: 215-220. DOI: 10.1179/Msc.1978.12.4.215  0.301
1976 Colliex C, Cosslett VE, Leapman RD, Trebbia P. Contribution of electron energy loss spectroscopy to the development of analytical electron microscopy Ultramicroscopy. 1: 301-315. PMID 1028200 DOI: 10.1016/0304-3991(76)90048-6  0.375
1976 Leapman RD, Cosslett VE. Extended fine structure above the X-ray edge in electron energy loss spectra Journal of Physics D: Applied Physics. 9: L29-L32. DOI: 10.1088/0022-3727/9/2/003  0.334
1976 Leapman RD, Cosslett VE. ELECTRON ENERGY LOSS SPECTROMETRY: MEAN FREE PATHS FOR SOME CHARACTERISTIC X-RAY EXCITATIONS Philos Mag. 33: 1-10. DOI: 10.1080/14786437608221086  0.338
1976 Leapman RD, Cosslett VE. Electron spectrometry of inner shell excitations Vacuum. 26: 423-426. DOI: 10.1016/0042-207X(76)90212-8  0.367
Low-probability matches (unlikely to be authored by this person)
2005 Petkova AT, Leapman RD, Guo Z, Yau WM, Mattson MP, Tycko R. Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils. Science (New York, N.Y.). 307: 262-5. PMID 15653506 DOI: 10.1126/Science.1105850  0.299
2016 Yadav S, Williamson JK, Aronova MA, Prince AA, Pokrovskaya ID, Leapman RD, Storrie B. Golgi proteins in circulating human platelets are distributed across non-stacked, scattered structures. Platelets. 1-9. PMID 27753523 DOI: 10.1080/09537104.2016.1235685  0.299
2008 Trachtenberg S, Dorward LM, Speransky VV, Jaffe H, Andrews SB, Leapman RD. Structure of the cytoskeleton of Spiroplasma melliferum BC3 and its interactions with the cell membrane. Journal of Molecular Biology. 378: 778-89. PMID 18400234 DOI: 10.1016/J.Jmb.2008.02.020  0.297
2013 Abreu F, Sousa AA, Aronova MA, Kim Y, Cox D, Leapman RD, Andrade LR, Kachar B, Bazylinski DA, Lins U. Cryo-electron tomography of the magnetotactic vibrio Magnetovibrio blakemorei: insights into the biomineralization of prismatic magnetosomes. Journal of Structural Biology. 181: 162-8. PMID 23246783 DOI: 10.1016/J.Jsb.2012.12.002  0.296
1995 Urquhart SG, Hitchcock AP, Leapman RD, Priester RD, Rightor EG. Analysis of polyurethanes using core excitation spectroscopy. Part I: Model polyurethane foam polymers Journal of Polymer Science Part B: Polymer Physics. 33: 1593-1602. DOI: 10.1002/Polb.1995.090331104  0.295
2011 Bhirde AA, Liu G, Jin A, Iglesias-Bartolome R, Sousa AA, Leapman RD, Gutkind JS, Lee S, Chen X. Combining portable Raman probes with nanotubes for theranostic applications. Theranostics. 1: 310-21. PMID 21769298 DOI: 10.7150/Thno/V01P0310  0.295
2008 Paravastu AK, Leapman RD, Yau WM, Tycko R. Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America. 105: 18349-54. PMID 19015532 DOI: 10.1073/Pnas.0806270105  0.295
2015 Pfeifer CR, Shomorony A, Aronova MA, Zhang G, Cai T, Xu H, Notkins AL, Leapman RD. Quantitative analysis of mouse pancreatic islet architecture by serial block-face SEM. Journal of Structural Biology. 189: 44-52. PMID 25448885 DOI: 10.1016/J.Jsb.2014.10.013  0.294
2015 Pokrovskaya ID, Aronova MA, Kamykowski JA, Prince AA, Hoyne JD, Calco GN, Kuo BC, He Q, Leapman RD, Storrie B. STEM Tomography Reveals that the Canalicular System and α-Granules Remain Separate Compartments During Early Secretion Stages in Blood Platelets. Journal of Thrombosis and Haemostasis : Jth. PMID 26663480 DOI: 10.1111/Jth.13225  0.293
1988 Dvorak JA, Engel JC, Leapman RD, Swyt CR, Pella PA. Trypanosoma cruzi: elemental composition heterogeneity of cloned stocks. Molecular and Biochemical Parasitology. 31: 19-26. PMID 3054539 DOI: 10.1016/0166-6851(88)90141-7  0.292
1993 Andrews SB, Gallant PE, Leapman RD, Schnapp BJ, Reese TS. Single kinesin molecules crossbridge microtubules in vitro. Proceedings of the National Academy of Sciences of the United States of America. 90: 6503-7. PMID 8341662 DOI: 10.1073/Pnas.90.14.6503  0.292
2007 Chesnick IE, Avallone FA, Leapman RD, Landis WJ, Eidelman N, Potter K. Evaluation of bioreactor-cultivated bone by magnetic resonance microscopy and FTIR microspectroscopy. Bone. 40: 904-12. PMID 17174620 DOI: 10.1016/J.Bone.2006.10.020  0.291
1994 Andrews SB, Buchanan RA, Leapman RD. Quantitative dark-field mass analysis of ultrathin cryosections in the field-emission scanning transmission electron microscope. Scanning Microscopy. Supplement. 8: 13-23; discussion 23. PMID 7638482  0.29
1982 Leapman RD, Grunes LA, Fejes PL. Study of the L23 edges in the 3d transition metals and their oxides by electron-energy-loss spectroscopy with comparisons to theory Physical Review B. 26: 614-635. DOI: 10.1103/Physrevb.26.614  0.289
2011 Chen X, Nelson CD, Li X, Winters CA, Azzam R, Sousa AA, Leapman RD, Gainer H, Sheng M, Reese TS. PSD-95 is required to sustain the molecular organization of the postsynaptic density. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6329-38. PMID 21525273 DOI: 10.1523/Jneurosci.5968-10.2011  0.289
2016 Bryant LH, Kim SJ, Hobson M, Milo B, Kovacs ZI, Jikiria N, Lewis BK, Aronova MA, Sousa AA, Zhang G, Leapman RD, Frank JA. Physicochemical Characterization of Ferumoxytol, Heparin and Protamine Nanocomplexes for improved magnetic labeling of stem cells. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27520728 DOI: 10.1016/J.Nano.2016.07.011  0.288
1979 Leapman RD. ENERGY LOSS SPECTROSCOPY OF CORE EXCITATIONS AND QUANTITATIVE MICROANALYSIS Ultramicroscopy. 2: 413-421. DOI: 10.1016/S0304-3991(78)80065-5  0.287
2009 Sousa AA, Hohmann-Marriott MF, Azari A, Zhang G, Leapman RD. BF STEM tomography for improved 3D imaging of thick biological sections Microscopy and Microanalysis. 15: 572-573. DOI: 10.1017/S1431927609093659  0.286
2002 Potter K, Leapman RD, Basser PJ, Landis WJ. Cartilage calcification studied by proton nuclear magnetic resonance microscopy. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 652-60. PMID 11918222 DOI: 10.1359/Jbmr.2002.17.4.652  0.284
2013 Huang P, Lin J, Li W, Rong P, Wang Z, Wang S, Wang X, Sun X, Aronova M, Niu G, Leapman RD, Nie Z, Chen X. Biodegradable gold nanovesicles with an ultrastrong plasmonic coupling effect for photoacoustic imaging and photothermal therapy. Angewandte Chemie (International Ed. in English). 52: 13958-64. PMID 24318645 DOI: 10.1002/Anie.201308986  0.284
2010 Bhirde AA, Patel S, Sousa AA, Patel V, Molinolo AA, Ji Y, Leapman RD, Gutkind JS, Rusling JF. Distribution and clearance of PEG-single-walled carbon nanotube cancer drug delivery vehicles in mice. Nanomedicine (London, England). 5: 1535-46. PMID 21143032 DOI: 10.2217/Nnm.10.90  0.283
2010 Leapman R, Sousa A, Aronova M. Quantitative EFTEM and STEM Tomography of Soft Materials Microscopy and Microanalysis. 16: 1840-1841. DOI: 10.1017/S1431927610058782  0.283
2002 Center RJ, Leapman RD, Lebowitz J, Arthur LO, Earl PL, Moss B. Oligomeric structure of the human immunodeficiency virus type 1 envelope protein on the virion surface. Journal of Virology. 76: 7863-7. PMID 12097599 DOI: 10.1128/Jvi.76.15.7863-7867.2002  0.283
1987 Andrews SB, Leapman RD, Landis DM, Reese TS. Distribution of calcium and potassium in presynaptic nerve terminals from cerebellar cortex. Proceedings of the National Academy of Sciences of the United States of America. 84: 1713-7. PMID 3470753 DOI: 10.1073/Pnas.84.6.1713  0.28
2018 Aronova M, Byrnes C, Lee Y, Zhang G, Kim Y, Meier E, Leapman R. Quantitative STEM-EELS Imaging of Ferritin Distributions in Cultured Erythroblasts Undergoing Erythropoiesis Microscopy and Microanalysis. 24: 2034-2035. DOI: 10.1017/S1431927618010656  0.28
2013 Sousa A, Zhang J, Chen X, Diamond J, Reese T, Leapman R. Three-Dimensional Reconstruction of Whole Synapses by STEM Tomography Microscopy and Microanalysis. 19: 558-559. DOI: 10.1017/S1431927613004789  0.279
1980 Grunes LA, Leapman RD. Optically forbidden excitations of the 3s subshell in the 3d transition metals by inelastic scattering of fast electrons Physical Review B. 22: 3778-3783. DOI: 10.1103/Physrevb.22.3778  0.279
2016 Knittel LL, Hassan SA, Aronova MA, Schuck P, Leapman RD, Sousa AA. Biointeractions of Ultrasmall Gold Nanoparticles: Influence of Nanoparticle Size and Surface Chemistry Biophysical Journal. 110: 530a. DOI: 10.1016/J.Bpj.2015.11.2833  0.279
2019 He Q, Guay MD, Zhang G, Leapman RD. Improved Visualization of Structure at the Nano-Scale in Entire Eukaryotic Cells by Fine Alignment of Serial Block Face Sem Image Stacks Biophysical Journal. 116: 575a. DOI: 10.1016/J.Bpj.2018.11.3092  0.278
1993 Foster MC, Leapman RD, Li MX, Atwater I. Elemental composition of secretory granules in pancreatic islets of Langerhans. Biophysical Journal. 64: 525-32. PMID 8457676 DOI: 10.1016/S0006-3495(93)81397-3  0.278
1988 Fiori CE, Leapman RD, Swyt CR, Andrews SB. Quantitative X-ray mapping of biological cryosections. Ultramicroscopy. 24: 237-49. PMID 3281357 DOI: 10.1016/0304-3991(88)90313-0  0.277
1980 Leapman RD, Rez P, Mayers DF. K, L, and M shell generalized oscillator strengths and ionization cross sections for fast electron collisions The Journal of Chemical Physics. 72: 1232-1243. DOI: 10.1063/1.439184  0.276
2020 Pokrovskaya I, Tobin M, Desai R, Aronova MA, Kamykowski JA, Zhang G, Joshi S, Whiteheart SW, Leapman RD, Storrie B. Structural analysis of resting mouse platelets by 3D-EM Reveals an unexpected variation in α-granule shape. Platelets. 1-10. PMID 32815431 DOI: 10.1080/09537104.2020.1799970  0.276
2018 Pokrovskaya ID, Storrie B, Yadav S, Rao A, McBride E, Aronova M, Leapman R. Alpha-Granules in Resting Human Platelets Are a Spatially Clustered, Single Major Population Blood. 132: 865-865. DOI: 10.1182/Blood-2018-99-119483  0.275
2012 Leapman R, Sousa A, Morgan J, Adams A, Zhang G, Aronova M, Bryant L, Frank J. Characterization of hybrid nanoparticles by EFTEM and STEM Microscopy and Microanalysis. 18: 1596-1597. DOI: 10.1017/S143192761200983X  0.275
1999 Andrews SB, Pivovarova NB, Hongpaisan J, Leapman RD. High-Resolution Analysis of Rapidly Frozen Biological Specimens: Capabilities and Limitations Microscopy and Microanalysis. 5: 412-413. DOI: 10.1017/S1431927600015385  0.274
2007 Zhang G, Hirai H, Cai T, Miura J, Yu P, Huang H, Schiller MR, Swaim WD, Leapman RD, Notkins AL. RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose. The Journal of Endocrinology. 195: 313-21. PMID 17951542 DOI: 10.1677/Joe-07-0252  0.274
2001 Center RJ, Schuck P, Leapman RD, Arthur LO, Earl PL, Moss B, Lebowitz J. Oligomeric structure of virion-associated and soluble forms of the simian immunodeficiency virus envelope protein in the prefusion activated conformation. Proceedings of the National Academy of Sciences of the United States of America. 98: 14877-82. PMID 11752436 DOI: 10.1073/Pnas.261573898  0.274
2002 Antzutkin ON, Leapman RD, Balbach JJ, Tycko R. Supramolecular structural constraints on Alzheimer's β-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance Biochemistry. 41: 15436-15450. PMID 12484785 DOI: 10.1021/Bi0204185  0.273
2014 Graydon CW, Zhang J, Oesch NW, Sousa AA, Leapman RD, Diamond JS. Passive diffusion as a mechanism underlying ribbon synapse vesicle release and resupply. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8948-62. PMID 24990916 DOI: 10.1523/Jneurosci.1022-14.2014  0.272
2011 Aronova MA, Sousa AA, Leapman RD. EELS characterization of radiolytic products in frozen samples. Micron (Oxford, England : 1993). 42: 252-6. PMID 21111626 DOI: 10.1016/J.Micron.2010.10.009  0.272
2014 Aronova MA, Leapman RD. Compositional imaging of cells and bionanoparticles by EFTEM Microscopy and Microanalysis. 20: 1298-1299. DOI: 10.1017/S1431927614008228  0.272
2018 Guay MD, Emam ZA, Anderson AB, Leapman RD. Exploring Deep Neural Network Architectures for Automated Electron Micrograph Segmentation Biophysical Journal. 114: 343a. DOI: 10.1016/J.Bpj.2017.11.1916  0.269
2006 Leapman RD, Zhang G, Dorward L, Speransky V, Aronova MA. 2D and 3D elemental mapping of biological structures by energy-filtered TEM Microscopy and Microanalysis. 12: 1386-1387. DOI: 10.1017/S143192760606630X  0.269
2015 Chen X, Levy JM, Hou A, Winters C, Azzam R, Sousa AA, Leapman RD, Nicoll RA, Reese TS. PSD-95 family MAGUKs are essential for anchoring AMPA and NMDA receptor complexes at the postsynaptic density. Proceedings of the National Academy of Sciences of the United States of America. PMID 26604311 DOI: 10.1073/Pnas.1517045112  0.268
2008 Sousa A, Aronova MA, Wu H, Sarin H, Griffiths GL, Leapman RD. Quantitative STEM and EFTEM characterization of dendrimer-based nanoparticles used in magnetic resonance imaging and drug delivery Microscopy and Microanalysis. 14: 694-695. DOI: 10.1017/S143192760808224X  0.267
2008 Chen X, Winters C, Azzam R, Li X, Galbraith JA, Leapman RD, Reese TS. Organization of the core structure of the postsynaptic density. Proceedings of the National Academy of Sciences of the United States of America. 105: 4453-8. PMID 18326622 DOI: 10.1073/Pnas.0800897105  0.267
2020 Pokrovskaya ID, Tobin M, Desai R, Joshi S, Kamykowski JA, Zhang G, Aronova MA, Whiteheart SW, Leapman RD, Storrie B. Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis. Platelets. 1-8. PMID 32000578 DOI: 10.1080/09537104.2020.1719993  0.267
1988 Andrews SB, Leapman RD, Landis DM, Reese TS. Activity-dependent accumulation of calcium in Purkinje cell dendritic spines. Proceedings of the National Academy of Sciences of the United States of America. 85: 1682-5. PMID 3422755 DOI: 10.1073/Pnas.85.5.1682  0.266
2009 Paravastu AK, Qahwash I, Leapman RD, Meredith SC, Tycko R. Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure. Proceedings of the National Academy of Sciences of the United States of America. 106: 7443-8. PMID 19376973 DOI: 10.1073/Pnas.0812033106  0.266
2017 Sweeney AM, Fleming KE, McCauley JP, Rodriguez MF, Martin ET, Sousa AA, Leapman RD, Scimemi A. PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology. Scientific Reports. 7: 43606. PMID 28256580 DOI: 10.1038/Srep43606  0.265
2008 Aronova MA, Pivovarova NB, Andrews SB, Leapman RD. Megapixel quantitative EFTEM imaging of calcium in biological specimens Microscopy and Microanalysis. 14: 662-663. DOI: 10.1017/S143192760808464X  0.265
2007 Sousa A, Aronova M, Kim Y, Dorward L, Zhang G, Leapman R. Limits of Detection of Ultrasmall Gold Labels in Biological Specimens by STEM Tomography Microscopy and Microanalysis. 13. DOI: 10.1017/S1431927607074946  0.264
2002 Petkova AT, Ishii Y, Balbach JJ, Antzutkin ON, Leapman RD, Delaglio F, Tycko R. A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR Proceedings of the National Academy of Sciences of the United States of America. 99: 16742-16747. PMID 12481027 DOI: 10.1073/Pnas.262663499  0.264
2012 Sousa A, Cox D, Wankhede V, Leapman R, Chen X, Zhang J, Diamond J, Reese T. STEM tomography of micrometer-thick neuronal tissues Microscopy and Microanalysis. 18: 542-543. DOI: 10.1017/S1431927612004564  0.263
2005 Leapman RD, Zhang G, Talbot TL, Speransky VV, Kruhlak MJ. 3D elemental distributions in biological structures by EFTEM tomography Microscopy and Microanalysis. 11: 50-51. DOI: 10.1017/S1431927605502940  0.263
2004 Levin I, Kovler M, Roizin Y, Vofsi M, Leapman RD, Goodman G, Kawada N, Funahashi M. Structure, chemistry, and electrical performance of silicon oxide-nitride-oxide stacks on silicon Journal of the Electrochemical Society. 151: G833-G838. DOI: 10.1149/1.1811594  0.263
2020 He Q, Zhang G, Leapman R. Optimizing Specimen Thickness by Measuring Stain Density in STEM Tomography of Cells and Tissues Microscopy and Microanalysis. 1-2. DOI: 10.1017/S1431927620014191  0.263
2012 Norlin N, Hellberg M, Filippov A, Sousa AA, Gröbner G, Leapman RD, Almqvist N, Antzutkin ON. Aggregation and fibril morphology of the Arctic mutation of Alzheimer's Aβ peptide by CD, TEM, STEM and in situ AFM. Journal of Structural Biology. 180: 174-89. PMID 22750418 DOI: 10.1016/J.Jsb.2012.06.010  0.261
2011 Xie J, Zhang F, Aronova M, Zhu L, Lin X, Quan Q, Liu G, Zhang G, Choi KY, Kim K, Sun X, Lee S, Sun S, Leapman R, Chen X. Manipulating the power of an additional phase: a flower-like Au-Fe3O4 optical nanosensor for imaging protease expressions in vivo. Acs Nano. 5: 3043-51. PMID 21366330 DOI: 10.1021/Nn200161V  0.261
2015 Leapman R, Aronova M, Shomorony A, Pfeifer C, Hoyne J, Calco G, Kuo B, Zhang G, Xu H, Tao C, Notkins A. Architecture of Pancreatic Islets Imaged by Serial Block Face SEM Microscopy and Microanalysis. 21: 381-382. DOI: 10.1017/S1431927615002706  0.26
2016 He Q, Leapman RD. Choice of Specimen Thickness in Axial Bright-Field STEM Tomography of Cells Microscopy and Microanalysis. 22: 1138-1139. DOI: 10.1017/S143192761600653X  0.26
2011 Cai T, Hirai H, Zhang G, Zhang M, Takahashi N, Kasai H, Satin LS, Leapman RD, Notkins AL. Deletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesicles. Diabetologia. 54: 2347-57. PMID 21732083 DOI: 10.1007/S00125-011-2221-6  0.26
2000 Balbach JJ, Ishii Y, Antzutkin ON, Leapman RD, Rizzo NW, Dyda F, Reed J, Tycko R. Amyloid fibril formation by Aβ16-22, a seven-residue fragment of the Alzheimer's β-amyloid peptide, and structural characterization by solid state NMR Biochemistry. 39: 13748-13759. PMID 11076514 DOI: 10.1021/Bi0011330  0.257
2016 Sousa AA, Hassan SA, Knittel LL, Balbo A, Aronova MA, Brown PH, Schuck P, Leapman RD. Biointeractions of ultrasmall glutathione-coated gold nanoparticles: effect of small size variations. Nanoscale. PMID 26934984 DOI: 10.1039/C5Nr07642K  0.257
2012 Bhirde AA, Kapoor A, Liu G, Iglesias-Bartolome R, Jin A, Zhang G, Xing R, Lee S, Leapman RD, Gutkind JS, Chen X. Nuclear mapping of nanodrug delivery systems in dynamic cellular environments. Acs Nano. 6: 4966-72. PMID 22540867 DOI: 10.1021/Nn300516G  0.257
2009 Aronova MA, Sousa AA, Zhang G, Kruhlak MJ, Lei EP, Leapman RD. Correlative EFTEM, STEM and fluorescence microscopy as a tool for chromatin biology Microscopy and Microanalysis. 15: 920-921. DOI: 10.1017/S1431927609093556  0.257
2017 He Q, Joy DC, Zhang G, Leapman RD. Sub-Surface Serial Block Face SEM of Biological Structures at Near Isotropic Spatial Resolution Biophysical Journal. 112: 574a-575a. DOI: 10.1016/J.Bpj.2016.11.3093  0.256
1987 Silbermann M, Tenenbaum H, Livne E, Leapman R, von der Mark K, Reddi AH. The in vitro behavior of fetal condylar cartilage in serum-free hormone-supplemented medium. Bone. 8: 117-26. PMID 3593608 DOI: 10.1016/8756-3282(87)90080-9  0.255
2018 Shen Z, Song J, Zhou Z, Yung BC, Aronova MA, Li Y, Dai Y, Fan W, Liu Y, Li Z, Ruan H, Leapman RD, Lin L, Niu G, Chen X, et al. Dotted Core-Shell Nanoparticles for T -Weighted MRI of Tumors. Advanced Materials (Deerfield Beach, Fla.). e1803163. PMID 29972604 DOI: 10.1002/Adma.201803163  0.254
2019 Guay M, Emam Z, Leapman R. Two-stage Neural Architecture Search for Microscopy Image Segmentation Microscopy and Microanalysis. 25: 188-189. DOI: 10.1017/S1431927619001673  0.253
2011 Lin X, Xie J, Niu G, Zhang F, Gao H, Yang M, Quan Q, Aronova MA, Zhang G, Lee S, Leapman R, Chen X. Chimeric ferritin nanocages for multiple function loading and multimodal imaging. Nano Letters. 11: 814-9. PMID 21210706 DOI: 10.1021/Nl104141G  0.253
2008 Sousa AA, Hohmann-Marriott M, Zhang G, Leapman RD. Bright-Field STEM tomography of thick stained plastic sections Microscopy and Microanalysis. 14: 1066-1067. DOI: 10.1017/S1431927608082184  0.253
2010 Fukunaga M, Li TQ, van Gelderen P, de Zwart JA, Shmueli K, Yao B, Lee J, Maric D, Aronova MA, Zhang G, Leapman RD, Schenck JF, Merkle H, Duyn JH. Layer-specific variation of iron content in cerebral cortex as a source of MRI contrast. Proceedings of the National Academy of Sciences of the United States of America. 107: 3834-9. PMID 20133720 DOI: 10.1073/Pnas.0911177107  0.252
1995 Leapman R, Hunt J. Compositional Imaging with Electron Energy Loss Spectroscopy Microscopy and Microanalysis. 1: 93-108. DOI: 10.1017/S1431927695110934  0.251
1997 Thirion S, Troadec JD, Pagnotta S, Andrews SB, Leapman RD, Nicaise G. Calcium in secretory vesicles of neurohypophysial nerve endings: quantitative comparison by X-ray microanalysis of cryosectioned and freeze-substituted specimens. Journal of Microscopy. 186: 28-34. PMID 9159921 DOI: 10.1046/J.1365-2818.1997.1980760.X  0.251
2002 Kocsis E, Weisberg A, Moss B, Chen X, Reese TS, Leapman RD. Limits of specimen thickness for energy-filtered tomography of stained plastic sections at 120 kV beam voltage Microscopy and Microanalysis. 8: 882-883. DOI: 10.1017/S143192760210674X  0.251
2003 Laquerriere P, Kocsis E, Zhang G, Talbot TL, Leapman RD. Elemental tomography of biological structures Microscopy and Microanalysis. 9: 240-241. DOI: 10.1017/S1431927603440361  0.25
2006 Aronova MA, Zhang G, Leapman RD. Correction of thickness artifacts in EFTEM elemental mapping of biological specimens Microscopy and Microanalysis. 12: 1196-1197. DOI: 10.1017/S1431927606067055  0.249
2008 Chen X, Winters C, Azzam R, Crocker V, Li X, Galbraith J, Leapman R, Reese Ts. Identifying individual scaffolding molecules in the postsynaptic density. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 14: 1068-9. PMID 18674117 DOI: 10.1017/S1431927608085449  0.248
2009 Bhirde AA, Patel V, Gavard J, Zhang G, Sousa AA, Masedunskas A, Leapman RD, Weigert R, Gutkind JS, Rusling JF. Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery. Acs Nano. 3: 307-16. PMID 19236065 DOI: 10.1021/Nn800551S  0.248
2000 Antzutkin ON, Balbach JJ, Leapman RD, Rizzo NW, Reed J, Tycko R. Multiple quantum solid-state NMR indicates a parallel, not antiparallel, organization of β-sheets in Alzheimer's β-amyloid fibrils Proceedings of the National Academy of Sciences of the United States of America. 97: 13045-13050. PMID 11069287 DOI: 10.1073/Pnas.230315097  0.247
2011 Venzo A, Antonello S, Gascón JA, Guryanov I, Leapman RD, Perera NV, Sousa A, Zamuner M, Zanella A, Maran F. Effect of the charge state (z = -1, 0, +1) on the nuclear magnetic resonance of monodisperse Au25[S(CH2)2Ph]18(z) clusters. Analytical Chemistry. 83: 6355-62. PMID 21718063 DOI: 10.1021/Ac2012653  0.243
2004 Leapman RD, Kocsis E, Zhang G, Talbot TL, Laquerriere P. Mapping cellular elemental distributions in three dimensions Microscopy and Microanalysis. 10: 1182-1183. DOI: 10.1017/S1431927604881881  0.241
2007 Daly MJ, Gaidamakova EK, Matrosova VY, Vasilenko A, Zhai M, Leapman RD, Lai B, Ravel B, Li SM, Kemner KM, Fredrickson JK. Protein oxidation implicated as the primary determinant of bacterial radioresistance. Plos Biology. 5: e92. PMID 17373858 DOI: 10.1371/Journal.Pbio.0050092  0.241
2018 Pokrovskaya ID, Joshi S, Tobin M, Desai R, Aronova MA, Kamykowski JA, Zhang G, Whiteheart SW, Leapman RD, Storrie B. SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets. Blood Advances. 2: 2947-2958. PMID 30401752 DOI: 10.1182/Bloodadvances.2018019158  0.24
2015 Leapman R, Aronova M, Hoyne J, Calco G, Kuo B, He Q, Pokrovskaya I, MacDonald L, Prince A, Storrie B. Bright-Field STEM Tomography of Blood Platelets in Thick Sections Microscopy and Microanalysis. 21: 1287-1288. DOI: 10.1017/S1431927615007229  0.239
2008 Sarin H, Kanevsky AS, Wu H, Brimacombe KR, Fung SH, Sousa AA, Auh S, Wilson CM, Sharma K, Aronova MA, Leapman RD, Griffiths GL, Hall MD. Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells. Journal of Translational Medicine. 6: 80. PMID 19094226 DOI: 10.1186/1479-5876-6-80  0.238
2005 Zhang P, Land W, Lee S, Juliani J, Lefman J, Smith SR, Germain D, Kessel M, Leapman R, Rouault TA, Subramaniam S. Electron tomography of degenerating neurons in mice with abnormal regulation of iron metabolism Journal of Structural Biology. 150: 144-153. PMID 15866737 DOI: 10.1016/J.Jsb.2005.01.007  0.238
2005 Chen X, Vinade L, Leapman RD, Petersen JD, Nakagawa T, Phillips TM, Sheng M, Reese TS. Mass of the postsynaptic density and enumeration of three key molecules. Proceedings of the National Academy of Sciences of the United States of America. 102: 11551-6. PMID 16061821 DOI: 10.1073/Pnas.0505359102  0.237
2014 Pothayee N, Chen DY, Aronova MA, Qian C, Bouraoud N, Dodd S, Leapman RD, Koretsky AP. Self-organized Mn(2+)-Block Copolymer Complexes and Their Use for In Vivo MR Imaging of Biological Processes. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 2: 7055-7064. PMID 25364506 DOI: 10.1039/C4Tb00911H  0.237
2019 He Q, Guay M, Zhang G, Leapman R. Comparison of Techniques for Fine Alignment of Image Stacks in Serial Block-Face Electron Microscopy Microscopy and Microanalysis. 25: 148-149. DOI: 10.1017/S1431927619001478  0.237
1985 Leapman RD, Gorlen KE, Swyt CR. Digital processing of electron energy loss spectra and images. Scanning Electron Microscopy. 1-13. PMID 4001848  0.237
1998 Leapman RD, Swyt-Thomas CR, Agoston Dv, Pivovarova N, Andrews SB. Trace Element Quantitation in Biological X-Ray Microanalysis Microscopy and Microanalysis. 4: 212-213. DOI: 10.1017/S1431927600021188  0.236
2003 Leapman RD. PROCEEDINGS OF THE INTERNATIONAL WORKSHOP STRATEGIES AND ADVANCES IN ATOMIC LEVEL SPECTROSCOPY AND ANALYSIS Ultramicroscopy. 96: iii. DOI: 10.1016/S0304-3991(03)00158-X  0.232
2018 Mayorova TD, Smith CL, Hammar K, Winters CA, Pivovarova NB, Aronova MA, Leapman RD, Reese TS. Cells containing aragonite crystals mediate responses to gravity in Trichoplax adhaerens (Placozoa), an animal lacking neurons and synapses. Plos One. 13: e0190905. PMID 29342202 DOI: 10.1371/Journal.Pone.0190905  0.232
2004 Petkova AT, Buntkowsky G, Dyda F, Leapman RD, Yau WM, Tycko R. Solid state NMR reveals a pH-dependent antiparallel beta-sheet registry in fibrils formed by a beta-amyloid peptide. Journal of Molecular Biology. 335: 247-60. PMID 14659754 DOI: 10.1016/J.Jmb.2003.10.044  0.231
2011 Xing R, Zhang F, Xie J, Aronova M, Zhang G, Guo N, Huang X, Sun X, Liu G, Bryant LH, Bhirde A, Liang A, Hou Y, Leapman RD, Sun S, et al. Polyaspartic acid coated manganese oxide nanoparticles for efficient liver MRI. Nanoscale. 3: 4943-5. PMID 22064945 DOI: 10.1039/C1Nr11242B  0.229
2014 Bhirde AA, Chikkaveeraiah BV, Srivatsan A, Niu G, Jin AJ, Kapoor A, Wang Z, Patel S, Patel V, Gorbach AM, Leapman RD, Gutkind JS, Hight Walker AR, Chen X. Targeted therapeutic nanotubes influence the viscoelasticity of cancer cells to overcome drug resistance. Acs Nano. 8: 4177-89. PMID 24708375 DOI: 10.1021/Nn501223Q  0.229
1991 Leapman RD. Limits of detectability for parallel electron energy loss spectroscopy Institute of Physics Conference Series. 119: 95-100.  0.228
2017 Lu N, Huang P, Fan W, Wang Z, Liu Y, Wang S, Zhang G, Hu J, Liu W, Niu G, Leapman RD, Lu G, Chen X. Tri-stimuli-responsive biodegradable theranostics for mild hyperthermia enhanced chemotherapy. Biomaterials. 126: 39-48. PMID 28254692 DOI: 10.1016/J.Biomaterials.2017.02.025  0.226
2004 Center RJ, Lebowitz J, Leapman RD, Moss B. Promoting trimerization of soluble human immunodeficiency virus type 1 (HIV-1) Env through the use of HIV-1/simian immunodeficiency virus chimeras. Journal of Virology. 78: 2265-76. PMID 14963123 DOI: 10.1128/Jvi.78.5.2265-2276.2004  0.226
1999 Leapman R. Microanalysis and energy-filtering: Raimond Castaing's impact in biology Biology of the Cell. 91: 265-266. DOI: 10.1016/S0248-4900(99)90105-3  0.224
1997 Andrews SB, Pivovarova NB, Pozzo-Miller LD, Leapman RD. What X-Ray Microanalysis Can Tell Us About The Regulation of Intracellular Calcium Microscopy and Microanalysis. 3: 915-916. DOI: 10.1017/S1431927600011466  0.224
1995 Sun SQ, Shi SL, Hunt JA, Leapman RD. Quantitative water mapping of cryosectioned cells by electron energy-loss spectroscopy. Journal of Microscopy. 177: 18-30. PMID 7897645  0.224
1977 Leapman RD, Whelan MJ. MICROANALYSIS BY ELECTRON ENERGY LOSS SPECTROMETRY Inst Phys Conf Ser. 361-364.  0.223
2006 Leapman RD. Detection limits for EELS analysis of biological materials Microscopy and Microanalysis. 12: 104-105. DOI: 10.1017/S1431927606066426  0.222
2016 Zhu G, Liu Y, Yang X, Kim YH, Zhang H, Jia R, Liao HS, Jin A, Lin J, Aronova M, Leapman R, Nie Z, Niu G, Chen X. DNA-inorganic hybrid nanovaccine for cancer immunotherapy. Nanoscale. PMID 26947116 DOI: 10.1039/C5Nr08821F  0.218
1983 Leapman RD, Swyt CR. ELECTRON ENERGY LOSS IMAGING IN THE STEM: SYSTEMATIC AND STATISTICAL ERRORS Proceedings, Annual Conference - Microbeam Analysis Society. 163-167.  0.217
2008 Chen X, Winters C, Azzam R, Li X, Galbraith JA, Leapman RD, Reese TS. Organization of the core structure of the postsynaptic density (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, 11 (4453-4458) DOI: 10.1073/pnas.0800897105) Proceedings of the National Academy of Sciences of the United States of America. 105: 7893. DOI: 10.1073/Pnas.0803900105  0.215
2003 Andrews SB, Pivovarova NB, Hongpaisan J, Brantner CA, Leapman RD. Correlated measurements of free and total intracellular calcium Microscopy and Microanalysis. 9: 238-239. DOI: 10.1017/S1431927603440221  0.215
2008 Leapman RD. Nanoscale elemental analysis by EELS in the life sciences Microscopy and Microanalysis. 14: 1378-1379. DOI: 10.1017/S143192760808238X  0.214
1982 Swyt CR, Leapman RD. Plural scattering in electron energy loss spectroscopy (EELS) microanalysis Scanning Electron Microscopy. 1982: 73-82.  0.213
1982 Leapman RD. APPLICATIONS OF ELECTRON ENERGY LOSS SPECTROSCOPY IN BIOLOGY: DETECTION OF CALCIUM AND FLUORINE Proceedings - Electron Microscopy Society of America. 412-415.  0.213
2017 Zhu L, Almaça J, Dadi PK, Hong H, Sakamoto W, Rossi M, Lee RJ, Vierra NC, Lu H, Cui Y, McMillin SM, Perry NA, Gurevich VV, Lee A, Kuo B, ... Leapman RD, et al. β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions. Nature Communications. 8: 14295. PMID 28145434 DOI: 10.1038/Ncomms14295  0.211
1976 Leapman RD, Cosslett VE. MICROANALYSIS BY ELECTRON SPECTROMETRY OF INNER SHELL EXCITATIONS . 133-136.  0.211
2009 Sarin H, Kanevsky AS, Wu H, Sousa AA, Wilson CM, Aronova MA, Griffiths GL, Leapman RD, Vo HQ. Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors. Journal of Translational Medicine. 7: 51. PMID 19549317 DOI: 10.1186/1479-5876-7-51  0.208
2019 Storrie B, Rhee SW, Pokrovskaya ID, Ling K, Vedanaparti Y, Aronova M, Stalker TJ, Brass LF, Leapman R. Platelet Activation State Intermixing in a Venous Puncture Model Indicates Novel Patterns of Thrombus Formation. Blood. 134: 9. PMID 31724024 DOI: 10.1182/Blood-2019-130805  0.207
1987 Livne E, Oliver C, Leapman RD, Rosenberg LC, Poole AR, Silbermann M. Age-related changes in the role of matrix vesicles in the mandibular condylar cartilage. Journal of Anatomy. 150: 61-74. PMID 3308799  0.206
2001 Hongpaisan J, Pivovarova NB, Colegrove SL, Leapman RD, Friel DD, Andrews SB. Multiple modes of calcium-induced calcium release in sympathetic neurons II: a [Ca2+](i)- and location-dependent transition from endoplasmic reticulum Ca accumulation to net Ca release. The Journal of General Physiology. 118: 101-12. PMID 11429447 DOI: 10.1085/Jgp.118.1.101  0.205
2016 Leapman R, Hoyne J, Kuo B, Calco G, Zhang G, Aronova M. Analysis of Mitochondrial Networks by Serial Block Face SEM Microscopy and Microanalysis. 22: 1104-1105. DOI: 10.1017/S143192761600636X  0.204
2020 Leapman R, Aronova M. Advances and Applications of EELS in Biology Microscopy and Microanalysis. 1-4. DOI: 10.1017/S1431927620014804  0.194
2000 Levin I, Leapman RD, Kaiser DL. Microstructure and chemistry of nonstoichiometric (Ba,Sr)TiO3 thin films deposited by metalorganic chemical vapor deposition Journal of Materials Research. 15: 1433-1436. DOI: 10.1557/Jmr.2000.0207  0.191
1985 Livne E, Oliver C, Leapman R, Silbermann M, Poole A, Rosenberg L. Matrix vesicles in condylar cartilage of aging mice Bone. 6: 474. DOI: 10.1016/8756-3282(85)90251-0  0.188
1990 ROM WN, CHURG A, LEAPMAN R, FIORI C, SWYT C. Evaluation of Alveolar Macrophage Particle Burden in Individuals Occupationally Exposed to Inorganic Dusts Journal of Aerosol Medicine. 3: S-43-S-56. DOI: 10.1089/Jam.1990.3.Suppl_1.S-43  0.182
2013 Leapman R, Aronova M. Quantitation of Overlapping Core Edges in EFTEM Spectrum Imaging of Cells Microscopy and Microanalysis. 19: 1078-1079. DOI: 10.1017/S1431927613007381  0.18
2018 He Q, Joy D, Zhang G, Leapman R. Improved Z-axis Resolution in Serial Block Face SEM with Dual Primary Energies and Monte Carlo Simulation of Electron Scattering Microscopy and Microanalysis. 24: 1440-1441. DOI: 10.1017/s1431927618007687  0.173
2023 Leapman RD. Contributions of David Joy to Electron Microscopy at the NIH (ca. 1980-2020). Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 29: 456-457. PMID 37613231 DOI: 10.1093/micmic/ozad067.214  0.172
2022 Chen X, Crosby KC, Feng A, Purkey AM, Aronova MA, Winters CA, Crocker VT, Leapman RD, Reese TS, Dell'Acqua ML. Palmitoylation of A-kinase anchoring protein 79/150 modulates its nanoscale organization, trafficking, and mobility in postsynaptic spines. Frontiers in Synaptic Neuroscience. 14: 1004154. PMID 36186623 DOI: 10.3389/fnsyn.2022.1004154  0.163
2021 Guay MD, Emam ZAS, Anderson AB, Aronova MA, Pokrovskaya ID, Storrie B, Leapman RD. Dense cellular segmentation for EM using 2D-3D neural network ensembles. Scientific Reports. 11: 2561. PMID 33510185 DOI: 10.1038/s41598-021-81590-0  0.159
2021 Aronova MA, Noh SJ, Zhang G, Byrnes C, Meier ER, Kim YC, Leapman RD. Use of dual-electron probes reveals the role of ferritin as an iron depot in erythropoiesis. Iscience. 24: 102901. PMID 34401678 DOI: 10.1016/j.isci.2021.102901  0.136
2020 Pokrovskaya ID, Yadav S, Rao A, McBride E, Kamykowski JA, Zhang G, Aronova MA, Leapman RD, Storrie B. 3D ultrastructural analysis of α-granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets. Research and Practice in Thrombosis and Haemostasis. 4: 72-85. PMID 31989087 DOI: 10.1002/rth2.12260  0.134
2010 Aronova MA, Kim YC, Sousa AA, Zhang G, Leapman RD. Nanoscale imaging of chemical elements in biomedicine Ifmbe Proceedings. 32: 357-360. DOI: 10.1007/978-3-642-14998-6_91  0.125
1994 Quintana C, Bonnet N, Lindh U, De Bruijn WC, Von Zglinicki T, Leapman RD. Multivariate statistical analysis applied to X-ray spectra and X-ray mapping of liver cell nuclei Scanning Microscopy. 8: 563-586. PMID 7747157  0.122
2023 Joshi S, Smith AN, Prakhya KS, Alfar HR, Lykins J, Zhang M, Pokrovskaya I, Aronova M, Leapman RD, Storrie B, Whiteheart SW. Ferric Chloride-Induced Arterial Thrombosis and Sample Collection for 3D Electron Microscopy Analysis. Journal of Visualized Experiments : Jove. PMID 37010311 DOI: 10.3791/64985  0.121
2003 Leapman R. Ultramicroscopy: Foreword Ultramicroscopy. 96: v-vi. DOI: 10.1016/S0304-3991(03)00089-5  0.12
1994 Shi SL, Sun SQ, Nash TE, Leapman RD. Characterization of cryosectioned cell suspensions by STEM Proceedings - Annual Meeting, Microscopy Society of America. 136-137.  0.119
1988 Ornberg RL, Kuijpers GA, Leapman RD. Electron probe microanalysis of the subcellular compartments of bovine adrenal chromaffin cells. Comparison of chromaffin granules in situ and in vitro. The Journal of Biological Chemistry. 263: 1488-93. PMID 3335554  0.116
2021 Rhee SW, Pokrovskaya ID, Ball KK, Ling K, Vedanaparti Y, Cohen J, Cruz DRD, Zhao OS, Aronova MA, Zhang G, Kamykowski JA, Leapman RD, Storrie B. Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates. Communications Biology. 4: 1090. PMID 34531522 DOI: 10.1038/s42003-021-02615-y  0.112
2014 Chen X, Winters C, Azzam R, Sousa AA, Leapman RD, Reese TS. Nanoscale imaging of protein molecules at the postsynaptic density Neuromethods. 84: 1-21. DOI: 10.1007/978-1-4614-9179-8_1  0.111
2014 Chen X, Winters C, Azzam R, Sousa AA, Leapman RD, Reese TS. Nanoscale imaging of protein molecules at the postsynaptic density Neuromethods. 84: 1-21. DOI: 10.1007/978-1-4614-9179-8-1  0.111
2023 Matharu SS, Nordmann CS, Ottman KR, Akkem R, Palumbo D, Cruz DRD, Campbell K, Sievert G, Sturgill J, Porterfield JZ, Joshi S, Alfar HR, Peng C, Pokrovskaya ID, Kamykowski JA, ... ... Leapman RD, et al. Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets. Platelets. 34: 2264978. PMID 37933490 DOI: 10.1080/09537104.2023.2264978  0.095
1997 Pozzo-Miller LD, Pivovarova NB, Leapman RD, Buchanan RA, Reese TS, Andrews SB. Activity-dependent calcium sequestration in dendrites of hippocampal neurons in brain slices. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8729-38. PMID 9348342  0.094
2020 McCauley JP, Petroccione MA, D'Brant LY, Todd GC, Affinnih N, Wisnoski JJ, Zahid S, Shree S, Sousa AA, De Guzman RM, Migliore R, Brazhe A, Leapman RD, Khmaladze A, Semyanov A, et al. Circadian Modulation of Neurons and Astrocytes Controls Synaptic Plasticity in Hippocampal Area CA1. Cell Reports. 33: 108255. PMID 33053337 DOI: 10.1016/j.celrep.2020.108255  0.086
1993 Leapman RD, Sun SQ, Shi SL, Buchanan RA, Andrews SB. STEM measurement of subcellular water distributions Proceedings - Annual Meeting, Microscopy Society of America. 568-569.  0.084
1999 Thirion S, Troadec JD, Pivovarova NB, Pagnotta S, Andrews SB, Leapman RD, Nicaise G. Stimulus-secretion coupling in neurohypophysial nerve endings: a role for intravesicular sodium? Proceedings of the National Academy of Sciences of the United States of America. 96: 3206-10. PMID 10077662 DOI: 10.1073/pnas.96.6.3206  0.082
1982 Leapman RD. EXELFS SPECTROSCOPY OF AMORPHOUS MATERIALS Proceedings, Annual Conference - Microbeam Analysis Society. 111-117.  0.067
2023 Pokrovskaya ID, Rhee SW, Ball KK, Kamykowski JA, Zhao OS, Cruz DRD, Cohen J, Aronova MA, Leapman RD, Storrie B. Tethered platelet capture provides a mechanism for restricting circulating platelet activation to the wound site. Research and Practice in Thrombosis and Haemostasis. 7: 100058. PMID 36865905 DOI: 10.1016/j.rpth.2023.100058  0.056
2014 Leapman RD, Aronova MA. EELS and EFTEM analysis of biological materials Microscopy and Microanalysis. 20: 582-583. DOI: 10.1017/S1431927614004632  0.054
1993 Leapman RD, Brink J, Chiu W. Thickness measurement of glucose-embedded crotoxin complex crystals by EELS Proceedings - Annual Meeting, Microscopy Society of America. 686-687.  0.041
1980 Leapman RD, Grunes LA. Anomalous L3L2 white-line ratios in the 3d transition metals Physical Review Letters. 45: 397-401. DOI: 10.1103/PhysRevLett.45.397  0.039
1984 Swyt CR, Leapman RD. REMOVAL OF PLURAL SCATTERING IN EELS: PRACTICAL CONSIDERATIONS Proceedings, Annual Conference - Microbeam Analysis Society. 45-48.  0.033
1987 Silbermann M, Reddi AH, Hand AR, Leapman RD, Von der Mark K, Franzen A. Further characterisation of the extracellular matrix in the mandibular condyle in neonatal mice. Journal of Anatomy. 151: 169-88. PMID 3308801  0.019
1994 Leapman RD, Sun SQ. EELS of ice, vitrified water, and frozen aqueous solutions Proceedings - Annual Meeting, Microscopy Society of America. 984-985.  0.019
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