Year |
Citation |
Score |
2014 |
Edwankar RV, Edwankar CR, Deschamps JR, Cook JM. General strategy for synthesis of C-19 methyl-substituted sarpagine/macroline/ajmaline indole alkaloids including total synthesis of 19(S),20(R)-dihydroperaksine, 19(S),20(R)-dihydroperaksine-17-al, and peraksine. The Journal of Organic Chemistry. 79: 10030-48. PMID 25247616 DOI: 10.1021/Jo5016163 |
0.784 |
|
2013 |
Edwankar CR, Edwankar RV, Namjoshi OA, Liao X, Cook JM. Stereospecific approach to the synthesis of ring-A oxygenated sarpagine indole alkaloids. Total synthesis of the dimeric indole alkaloid P-(+)-dispegatrine and six other monomeric indole alkaloids. The Journal of Organic Chemistry. 78: 6471-87. PMID 23721107 DOI: 10.1021/Jo400469T |
0.778 |
|
2012 |
Brusoe AT, Edwankar RV, Alexanian EJ. Enantioselective intermolecular [2 + 2 + 2] cycloadditions of ene-allenes with allenoates. Organic Letters. 14: 6096-9. PMID 23171471 DOI: 10.1021/Ol303024Q |
0.756 |
|
2012 |
Edwankar CR, Edwankar RV, Deschamps JR, Cook JM. Nature-inspired stereospecific total synthesis of P-(+)-dispegatrine and four other monomeric sarpagine indole alkaloids. Angewandte Chemie (International Ed. in English). 51: 11762-5. PMID 23073985 DOI: 10.1002/Anie.201206015 |
0.776 |
|
2012 |
Edwankar RV, Edwankar CR, Namjoshi OA, Deschamps JR, Cook JM. Brønsted acid mediated cyclization of enaminones. Rapid and efficient access to the tetracyclic framework of the Strychnos alkaloids. Journal of Natural Products. 75: 181-8. PMID 22257244 DOI: 10.1021/Np200759H |
0.76 |
|
2011 |
Edwankar RV, Edwankar CR, Deschamps J, Cook JM. Regiospecific, enantiospecific total synthesis of C-19 methyl substituted sarpagine alkaloids dihydroperaksine-17-al and dihydroperaksine. Organic Letters. 13: 5216-9. PMID 21877687 DOI: 10.1021/Ol202101P |
0.769 |
|
2011 |
Di Lio A, Benke D, Besson M, Desmeules J, Daali Y, Wang ZJ, Edwankar R, Cook JM, Zeilhofer HU. HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain. Neuropharmacology. 60: 626-32. PMID 21145329 DOI: 10.1016/J.Neuropharm.2010.11.026 |
0.429 |
|
2010 |
Fischer BD, Licata SC, Edwankar RV, Wang ZJ, Huang S, He X, Yu J, Zhou H, Johnson EM, Cook JM, Furtmüller R, Ramerstorfer J, Sieghart W, Roth BL, Majumder S, et al. Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure. Neuropharmacology. 59: 612-8. PMID 20727364 DOI: 10.1016/J.Neuropharm.2010.08.011 |
0.723 |
|
2010 |
Savić MM, Majumder S, Huang S, Edwankar RV, Furtmüller R, Joksimović S, Clayton T, Ramerstorfer J, Milinković MM, Roth BL, Sieghart W, Cook JM. Novel positive allosteric modulators of GABAA receptors: do subtle differences in activity at alpha1 plus alpha5 versus alpha2 plus alpha3 subunits account for dissimilarities in behavioral effects in rats? Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34: 376-86. PMID 20074611 DOI: 10.1016/J.Pnpbp.2010.01.004 |
0.698 |
|
2009 |
Edwankar CR, Edwankar RV, Namjoshi OA, Rallapalli SK, Yang J, Cook JM. Recent progress in the total synthesis of indole alkaloids. Current Opinion in Drug Discovery & Development. 12: 752-71. PMID 19894188 |
0.74 |
|
2009 |
Rivas FM, Stables JP, Murphree L, Edwankar RV, Edwankar CR, Huang S, Jain HD, Zhou H, Majumder S, Sankar S, Roth BL, Ramerstorfer J, Furtmüller R, Sieghart W, Cook JM. Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models. Journal of Medicinal Chemistry. 52: 1795-8. PMID 19275170 DOI: 10.1021/Jm801652D |
0.687 |
|
2008 |
Edwankar CR, Edwankar RV, Rallapalli S, Cook JM. General approach to the total synthesis of macroline-related sarpagine and ajmaline alkaloids Natural Product Communications. 3: 1839-1870. DOI: 10.1177/1934578X0800301114 |
0.723 |
|
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