Lei Hu - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
BK channels, HCN channels

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Saponaro A, Pauleta SR, Cantini F, Matzapetakis M, Hammann C, Donadoni C, Hu L, Thiel G, Banci L, Santoro B, Moroni A. Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function. Proceedings of the National Academy of Sciences of the United States of America. 111: 14577-82. PMID 25197093 DOI: 10.1073/Pnas.1410389111  0.603
2014 Siegelbaum SA, Hu L, Santoro B. TRIP(8B)Ing up and Down HCN Channel Gating and Trafficking Biophysical Journal. 106: 9a. DOI: 10.1016/j.bpj.2013.11.097  0.717
2013 Hu L, Santoro B, Saponaro A, Liu H, Moroni A, Siegelbaum S. Binding of the auxiliary subunit TRIP8b to HCN channels shifts the mode of action of cAMP. The Journal of General Physiology. 142: 599-612. PMID 24277603 DOI: 10.1085/jgp.201311013  0.703
2012 Hu L, Santoro B, Saponaro A, Liu H, Moroni A, Siegelbaum SA. TRIP8B Allosterically Regulates the Ability of cAMP to Enhance the HCN2 Channel Opening Biophysical Journal. 102: 130a. DOI: 10.1016/j.bpj.2011.11.723  0.733
2011 Santoro B, Hu L, Liu H, Saponaro A, Pian P, Piskorowski RA, Moroni A, Siegelbaum SA. TRIP8b regulates HCN1 channel trafficking and gating through two distinct C-terminal interaction sites. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4074-86. PMID 21411649 DOI: 10.1523/Jneurosci.5707-10.2011  0.707
2010 Chen YH, Hu L, Punta M, Bruni R, Hillerich B, Kloss B, Rost B, Love J, Siegelbaum SA, Hendrickson WA. Homologue structure of the SLAC1 anion channel for closing stomata in leaves. Nature. 467: 1074-80. PMID 20981093 DOI: 10.1038/Nature09487  0.654
2009 Santoro B, Piskorowski RA, Pian P, Hu L, Liu H, Siegelbaum SA. TRIP8b splice variants form a family of auxiliary subunits that regulate gating and trafficking of HCN channels in the brain. Neuron. 62: 802-13. PMID 19555649 DOI: 10.1016/J.Neuron.2009.05.009  0.694
2007 Yang H, Hu L, Shi J, Delaloye K, Horrigan FT, Cui J. Mg2+ mediates interaction between the voltage sensor and cytosolic domain to activate BK channels. Proceedings of the National Academy of Sciences of the United States of America. 104: 18270-5. PMID 17984060 DOI: 10.1073/pnas.0705873104  0.756
2006 Yang H, Hu L, Shi J, Cui J. Tuning magnesium sensitivity of BK channels by mutations. Biophysical Journal. 91: 2892-900. PMID 16877509 DOI: 10.1529/biophysj.106.090159  0.7
2006 Hu L, Yang H, Shi J, Cui J. Effects of multiple metal binding sites on calcium and magnesium-dependent activation of BK channels. The Journal of General Physiology. 127: 35-49. PMID 16344323 DOI: 10.1085/jgp.200509317  0.723
2003 Hu L, Shi J, Ma Z, Krishnamoorthy G, Sieling F, Zhang G, Horrigan FT, Cui J. Participation of the S4 voltage sensor in the Mg2+-dependent activation of large conductance (BK) K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 100: 10488-93. PMID 12925732 DOI: 10.1073/pnas.1834300100  0.663
2002 Shi J, Krishnamoorthy G, Yang Y, Hu L, Chaturvedi N, Harilal D, Qin J, Cui J. Mechanism of magnesium activation of calcium-activated potassium channels. Nature. 418: 876-80. PMID 12192410 DOI: 10.1038/nature00941  0.689
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