Shuh Narumiya - Publications

Affiliations: 
Kyoto University, Kyōto-shi, Kyōto-fu, Japan 
Area:
Prostaglandin/Rho signaling

351 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kubota H, Kunisawa K, Wulaer B, Hasegawa M, Kurahashi H, Sakata T, Tezuka H, Kugita M, Nagao S, Nagai T, Furuyashiki T, Narumiya S, Saito K, Nabeshima T, Mouri A. High salt induces cognitive impairment via the interaction of the angiotensin II-AT and prostaglandin E2-EP systems. British Journal of Pharmacology. PMID 37076133 DOI: 10.1111/bph.16093  0.518
2022 Kawamura N, Katsuura G, Yamada-Goto N, Nakama R, Kambe Y, Miyata A, Furuyashiki T, Narumiya S, Ogawa Y, Inui A. Brain fractalkine-CX3CR1 signalling is anti-obesity system as anorexigenic and anti-inflammatory actions in diet-induced obese mice. Scientific Reports. 12: 12604. PMID 35871167 DOI: 10.1038/s41598-022-16944-3  0.577
2020 Zheng J, Sariol A, Meyerholz D, Zhang Q, Abrahante Lloréns JE, Narumiya S, Perlman S. Prostaglandin D2 signaling in dendritic cells is critical for the development of EAE. Journal of Autoimmunity. 102508. PMID 32624353 DOI: 10.1016/J.Jaut.2020.102508  0.362
2020 Hosono K, Kojo K, Narumiya S, Majima M, Ito Y. Prostaglandin E receptor EP4 stimulates lymphangiogenesis to promote mucosal healing during DSS-induced colitis. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 128: 110264. PMID 32447215 DOI: 10.1016/j.biopha.2020.110264  0.35
2020 Nakamoto S, Ito Y, Nishizawa N, Goto T, Kojo K, Kumamoto Y, Watanabe M, Narumiya S, Majima M. EP3 signaling in dendritic cells promotes liver repair by inducing IL-13-mediated macrophage differentiation in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32112485 DOI: 10.1096/fj.201901955R  0.341
2020 Thumkeo D, Katsura Y, Nishimura Y, Kanchanawong P, Tohyama K, Ishizaki T, Kitajima S, Takahashi C, Hirata T, Watanabe N, Krummel MF, Narumiya S. mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse. Science Advances. 6: eaay2432. PMID 31911947 DOI: 10.1126/Sciadv.Aay2432  0.342
2020 Hida H, Mouri A, Takasu M, Muto R, Uchida M, Furuyashiki T, Narumiya S, Nabeshima T, Yamada K, Yoshimi A, Ozaki N, Noda Y. The role of prostaglandin E2 in environmental factors of psychiatric disorders Proceedings For Annual Meeting of the Japanese Pharmacological Society. 93: 3-P-282. DOI: 10.1254/jpssuppl.93.0_3-p-282  0.485
2019 Nie X, Kitaoka S, Shinohara M, Kakizuka A, Narumiya S, Furuyashiki T. Roles of Toll-like receptor 2/4, monoacylglycerol lipase, and cyclooxygenase in social defeat stress-induced prostaglandin E synthesis in the brain and their behavioral relevance. Scientific Reports. 9: 17548. PMID 31772309 DOI: 10.1038/S41598-019-54082-5  0.622
2019 Otaka F, Ito Y, Inoue T, Ohkubo H, Nishizawa N, Kojo K, Betto T, Yamane S, Narumiya S, Koizumi W, Majima M. Thromboxane A receptor signaling in endothelial cells attenuates monocrotaline-induced liver injury. Toxicology and Applied Pharmacology. 381: 114733. PMID 31470032 DOI: 10.1016/j.taap.2019.114733  0.345
2019 Kashiwagi H, Yuhki KI, Imamichi Y, Kojima F, Kumei S, Tasaki Y, Narumiya S, Ushikubi F. Prostaglandin F2α Facilitates Platelet Activation by Acting on Prostaglandin E2 Receptor Subtype EP3 and Thromboxane A2 Receptor TP in Mice. Thrombosis and Haemostasis. PMID 31129913 DOI: 10.1055/s-0039-1688906  0.339
2019 Aida-Yasuoka K, Nishimura N, Fujisawa N, Endo N, Narumiya S, Tohyama C. The role of prostaglandin E receptor EP1 in 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced neonatal hydronephrosis in mice. Toxicology. PMID 30641090 DOI: 10.1016/j.tox.2019.01.006  0.361
2019 Toyoda Y, Morimoto K, Suno R, Horita S, Yamashita K, Hirata K, Sekiguchi Y, Yasuda S, Shiroishi M, Shimizu T, Urushibata Y, Kajiwara Y, Inazumi T, Hotta Y, Asada H, ... ... Narumiya S, et al. Ligand binding to human prostaglandin E receptor EP at the lipid-bilayer interface. Nature Chemical Biology. 15: 18-26. PMID 30510193 DOI: 10.1038/S41589-018-0131-3  0.323
2019 Morimoto K, Suno R, Hotta Y, Yamashita K, Hirata K, Yamamoto M, Narumiya S, Iwata S, Kobayashi T. Crystal structure of the endogenous agonist-bound prostanoid receptor EP3. Nature Chemical Biology. 15: 8-10. PMID 30510192 DOI: 10.1038/S41589-018-0171-8  0.332
2019 Nie X, Kitaoka S, Tanaka K, Ogawa A, Nakano F, Imoto Y, Segi-Nishida E, Narumiya S, Furuyashiki T. A role of innate immune molecules in behavioral changes induced by repeated social defeat stress in mice Proceedings For Annual Meeting of the Japanese Pharmacological Society. 92: 2-P-023. DOI: 10.1254/JPSSUPPL.92.0_2-P-023  0.741
2019 Shiho K, Nie X, Tanaka K, Ogawa A, Segi-Nishida E, Narumiya S, Furuyashiki T. Repeated stress-induced behavioral changes and inflammation-like responses Proceedings For Annual Meeting of the Japanese Pharmacological Society. 92: 1-YS-2. DOI: 10.1254/JPSSUPPL.92.0_1-YS-2  0.724
2018 Yao C, Narumiya S. Prostaglandin-cytokine crosstalk in chronic inflammation. British Journal of Pharmacology. PMID 30381825 DOI: 10.1111/bph.14530  0.323
2018 Nie X, Kitaoka S, Tanaka K, Segi-Nishida E, Imoto Y, Ogawa A, Nakano F, Tomohiro A, Nakayama K, Taniguchi M, Mimori-Kiyosue Y, Kakizuka A, Narumiya S, Furuyashiki T. The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation. Neuron. PMID 30033154 DOI: 10.1016/J.Neuron.2018.06.035  0.766
2018 Higashida S, Nagai H, Nakayama K, Shinohara R, Taniguchi M, Nagai M, Hikida T, Yawata S, Ago Y, Kitaoka S, Narumiya S, Furuyashiki T. Repeated social defeat stress impairs attentional set shifting irrespective of social avoidance and increases female preference associated with heightened anxiety. Scientific Reports. 8: 10454. PMID 29993010 DOI: 10.1038/S41598-018-28803-1  0.565
2018 Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, et al. Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons. Human Molecular Genetics. PMID 29893844 DOI: 10.1093/Hmg/Ddy219  0.631
2017 Kumei S, Yuhki KI, Kojima F, Kashiwagi H, Imamichi Y, Okumura T, Narumiya S, Ushikubi F. Prostaglandin I2 suppresses the development of diet-induced nonalcoholic steatohepatitis in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29247122 DOI: 10.1096/fj.201700590R  0.372
2017 Shinohara R, Taniguchi M, Ehrlich AT, Yokogawa K, Deguchi Y, Cherasse Y, Lazarus M, Urade Y, Ogawa A, Kitaoka S, Sawa A, Narumiya S, Furuyashiki T. Dopamine D1 receptor subtype mediates acute stress-induced dendritic growth in excitatory neurons of the medial prefrontal cortex and contributes to suppression of stress susceptibility in mice. Molecular Psychiatry. 23: 1717-1730. PMID 28924188 DOI: 10.1038/Mp.2017.177  0.802
2017 Ota H, Katanosaka K, Murase S, Furuyashiki T, Narumiya S, Mizumura K. EP2 receptor plays pivotal roles in generating mechanical hyperalgesia after lengthening contraction. Scandinavian Journal of Medicine & Science in Sports. PMID 28759126 DOI: 10.1111/Sms.12954  0.593
2017 Vijay R, Fehr AR, Janowski AM, Athmer J, Wheeler DL, Grunewald M, Sompallae R, Kurup SP, Meyerholz DK, Sutterwala FS, Narumiya S, Perlman S. Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630327 DOI: 10.1073/Pnas.1704099114  0.365
2017 Ouhaddi Y, Nebbaki SS, Habouri L, Afif H, Lussier B, Kapoor M, Narumiya S, Pelletier JP, Martel-Pelletier J, Benderdour M, Fahmi H. Deletion of the prostaglandin D2 receptor DP1 exacerbates aging-associated and instability-induced osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28544596 DOI: 10.1002/Art.40160  0.349
2017 Aoki T, Frȍsen J, Fukuda M, Bando K, Shioi G, Tsuji K, Ollikainen E, Nozaki K, Laakkonen J, Narumiya S. Prostaglandin E2-EP2-NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms. Science Signaling. 10. PMID 28174280 DOI: 10.1126/scisignal.aah6037  0.309
2016 Deguchi Y, Harada M, Shinohara R, Lazarus M, Cherasse Y, Urade Y, Yamada D, Sekiguchi M, Watanabe D, Furuyashiki T, Narumiya S. mDia and ROCK Mediate Actin-Dependent Presynaptic Remodeling Regulating Synaptic Efficacy and Anxiety. Cell Reports. 17: 2405-2417. PMID 27880913 DOI: 10.1016/J.Celrep.2016.10.088  0.584
2016 Kawano Y, Fukui C, Shinohara M, Wakahashi K, Ishii S, Suzuki T, Sato M, Asada N, Kawano H, Minagawa K, Sada A, Furuyashiki T, Uematsu S, Akira S, Uede T, ... Narumiya S, et al. G-CSF-induced sympathetic tone provokes fever and primes anti-mobilizing functions of neutrophils via PGE2. Blood. PMID 27827823 DOI: 10.1182/Blood-2016-07-725754  0.609
2016 Hosono K, Isonaka R, Kawakami T, Narumiya S, Majima M. Signaling of Prostaglandin E Receptors, EP3 and EP4 Facilitates Wound Healing and Lymphangiogenesis with Enhanced Recruitment of M2 Macrophages in Mice. Plos One. 11: e0162532. PMID 27711210 DOI: 10.1371/journal.pone.0162532  0.383
2016 Amano H, Nakamura M, Ito Y, Kakutani H, Eshima K, Kitasato H, Narumiya S, Majima M. Thromboxane A synthase enhances blood flow recovery from hindlimb ischemia. The Journal of Surgical Research. 204: 153-63. PMID 27451882 DOI: 10.1016/j.jss.2016.04.011  0.315
2016 Ikezoe K, Oga T, Honda T, Hara-Chikuma M, Ma X, Tsuruyama T, Uno K, Fuchikami J, Tanizawa K, Handa T, Taguchi Y, Verkman AS, Narumiya S, Mishima M, Chin K. Aquaporin-3 potentiates allergic airway inflammation in ovalbumin-induced murine asthma. Scientific Reports. 6: 25781. PMID 27165276 DOI: 10.1038/srep25781  0.336
2016 Andoh T, Yamamoto A, Haza S, Yuhki KI, Ushikubi F, Narumiya S, Kuraishi Y. Thromboxane A2 is Involved in Itch-associated Responses in Mice with Atopic Dermatitis-like Skin Lesions. Acta Dermato-Venereologica. PMID 27066774 DOI: 10.2340/00015555-2437  0.342
2016 Duffin R, O'Connor RA, Crittenden S, Forster T, Yu C, Zheng X, Smyth D, Robb CT, Rossi F, Skouras C, Tang S, Richards J, Pellicoro A, Weller RB, Breyer RM, ... ... Narumiya S, et al. Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis. Science (New York, N.Y.). 351: 1333-8. PMID 26989254 DOI: 10.1126/science.aad9903  0.316
2016 Ikezoe K, Oga T, Honda T, Hara-Chikuma M, Ma X, Tsuruyama T, Uno K, Fuchikami J, Tanizawa K, Handa T, Taguchi Y, Verkman A, Narumiya S, Mishima M, Chin K. Aquaporin-3 potentiates murine asthma through mediating T-cell trafficking and chemokine production European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa1104  0.332
2016 Kitaoka S, Furuyashiki T, Imoto Y, Nakayama K, Narumiya S, Nie X, Ogawa A, Segi-Nishida E, Tanaka K, Tomohiro A. PS205. Innate immune molecules activate microglia in mPFC to induce neuronal and emotional changes in mice. The International Journal of Neuropsychopharmacology. 19: 75-75. DOI: 10.1093/Ijnp/Pyw043.205  0.747
2016 Shinohara R, Deguchi Y, Ehrlich A, Furuyashiki T, Kitaoka S, Narumiya S, Ogawa A, Sawa A, Taniguchi M, Yokogawa K. PS144. Dopamine D1 receptor in the medial prefrontal cortex mediates behavioral resilience under stress in mice The International Journal of Neuropsychopharmacology. 19: 49-49. DOI: 10.1093/Ijnp/Pyw043.144  0.79
2015 Inada M, Takita M, Yokoyama S, Watanabe K, Tominari T, Matsumoto C, Hirata M, Maru Y, Maruyama T, Sugimoto Y, Narumiya S, Uematsu S, Akira S, Murphy G, Nagase H, et al. Direct Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling that Drives Tumor Growth, Angiogenesis and Metastasis. The Journal of Biological Chemistry. PMID 26475855 DOI: 10.1074/Jbc.M115.669481  0.348
2015 Fujita T, Soontrapa K, Ito Y, Iwaisako K, Moniaga CS, Asagiri M, Majima M, Narumiya S. Hepatic stellate cells relay inflammation signaling from sinusoids to parenchyma in mouse models of immune-mediated hepatitis. Hepatology (Baltimore, Md.). PMID 26248612 DOI: 10.1002/hep.28112  0.318
2015 Ma X, Aoki T, Narumiya S. Prostaglandin E2-EP4 signaling persistently amplifies CD40-mediated induction of IL-23 p19 expression through canonical and non-canonical NF-κB pathways. Cellular & Molecular Immunology. PMID 26189370 DOI: 10.1038/cmi.2015.70  0.316
2015 Ma X, Aoki T, Tsuruyama T, Narumiya S. Definition of Prostaglandin E2-EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth. Cancer Research. 75: 2822-32. PMID 26018088 DOI: 10.1158/0008-5472.CAN-15-0125  0.326
2015 Kashiwagi H, Yuhki K, Kojima F, Kumei S, Takahata O, Sakai Y, Narumiya S, Ushikubi F. The novel prostaglandin I2 mimetic ONO-1301 escapes desensitization in an antiplatelet effect due to its inhibitory action on thromboxane A2 synthesis in mice. The Journal of Pharmacology and Experimental Therapeutics. 353: 269-78. PMID 25740898 DOI: 10.1124/jpet.115.222612  0.361
2015 Ko CY, Chu YY, Narumiya S, Chi JY, Furuyashiki T, Aoki T, Wang SM, Chang WC, Wang JM. The CCAAT/enhancer-binding protein delta/miR135a/thrombospondin 1 axis mediates PGE2-induced angiogenesis in Alzheimer's disease. Neurobiology of Aging. 36: 1356-68. PMID 25554493 DOI: 10.1016/J.Neurobiolaging.2014.11.020  0.592
2015 Mohan S, Narumiya S, Doré S. Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity. Neurotoxicology. 46: 53-9. PMID 25451967 DOI: 10.1016/j.neuro.2014.10.012  0.388
2014 Glushakov AV, Fazal JA, Narumiya S, Doré S. Role of the prostaglandin E2 EP1 receptor in traumatic brain injury. Plos One. 9: e113689. PMID 25426930 DOI: 10.1371/journal.pone.0113689  0.369
2014 Liu M, Saeki K, Matsunobu T, Okuno T, Koga T, Sugimoto Y, Yokoyama C, Nakamizo S, Kabashima K, Narumiya S, Shimizu T, Yokomizo T. 12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor. The Journal of Experimental Medicine. 211: 1063-78. PMID 24821912 DOI: 10.1084/jem.20132063  0.34
2014 Tippin BL, Kwong AM, Inadomi MJ, Lee OJ, Park JM, Materi AM, Buslon VS, Lin AM, Kudo LC, Karsten SL, French SW, Narumiya S, Urade Y, Salido E, Lin HJ. Intestinal tumor suppression in ApcMin/+ mice by prostaglandin D2 receptor PTGDR. Cancer Medicine. 3: 1041-51. PMID 24729479 DOI: 10.1002/Cam4.251  0.352
2014 Aoki T, Fukuda M, Nishimura M, Nozaki K, Narumiya S. Critical role of TNF-alpha-TNFR1 signaling in intracranial aneurysm formation. Acta Neuropathologica Communications. 2: 34. PMID 24685329 DOI: 10.1186/2051-5960-2-34  0.328
2014 Kawakami Y, Hirano S, Kinoshita M, Otsuki A, Suzuki-Yamamoto T, Suzuki M, Kimoto M, Sasabe S, Fukushima M, Kishimoto K, Izumi T, Oga T, Narumiya S, Sugahara M, Miyano M, et al. Neutralization of leukotriene C4 and D4 activity by monoclonal and single-chain antibodies. Biochimica Et Biophysica Acta. 1840: 1625-33. PMID 24361619 DOI: 10.1016/j.bbagen.2013.12.016  0.346
2014 Morimoto K, Shirata N, Taketomi Y, Tsuchiya S, Segi-Nishida E, Inazumi T, Kabashima K, Tanaka S, Murakami M, Narumiya S, Sugimoto Y. Prostaglandin E2-EP3 signaling induces inflammatory swelling by mast cell activation. Journal of Immunology (Baltimore, Md. : 1950). 192: 1130-7. PMID 24342806 DOI: 10.4049/jimmunol.1300290  0.724
2014 Sarashina H, Tsubosaka Y, Omori K, Aritake K, Nakagawa T, Hori M, Hirai H, Nakamura M, Narumiya S, Urade Y, Ozaki H, Murata T. Opposing immunomodulatory roles of prostaglandin D2 during the progression of skin inflammation. Journal of Immunology (Baltimore, Md. : 1950). 192: 459-65. PMID 24298012 DOI: 10.4049/jimmunol.1302080  0.374
2014 Kawano Y, Fukui C, Wakahashi K, Ishii S, Suzuki T, Sato M, Asada N, Kawano H, Minagawa K, Sada A, Uematsu S, Akira S, Uede T, Narumiya S, Matsui T, et al. Neutrophils Modulate Osteoblastic Niche for Hematopoietic Progenitors Via Prostaglandin E2 Production Triggered By Sympathetic Nervous System Blood. 124: 769-769. DOI: 10.1182/Blood.V124.21.769.769  0.372
2014 Sakata D, Yao C, Esaki Y, Li Y, Matsuoka T, Kuroiwa K, Sugimoto Y, Narumiya S. Prostaglandin E Receptor Subtypes EP2 and EP4 Promote TH1 Cell Differentiation and TH17 Cell Expansion Through Different Signaling Modules Inflammation Research. 58: S244-S248. DOI: 10.1007/BF03354229  0.366
2013 Nomachi A, Yoshinaga M, Liu J, Kanchanawong P, Tohyama K, Thumkeo D, Watanabe T, Narumiya S, Hirata T. Moesin controls clathrin-mediated S1PR1 internalization in T cells. Plos One. 8: e82590. PMID 24358210 DOI: 10.1371/Journal.Pone.0082590  0.37
2013 Watanabe S, De Zan T, Ishizaki T, Yasuda S, Kamijo H, Yamada D, Aoki T, Kiyonari H, Kaneko H, Shimizu R, Yamamoto M, Goshima G, Narumiya S. Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during mouse fetal erythropoiesis. Cell Reports. 5: 926-32. PMID 24239357 DOI: 10.1016/J.Celrep.2013.10.021  0.355
2013 Thumkeo D, Watanabe S, Narumiya S. Physiological roles of Rho and Rho effectors in mammals. European Journal of Cell Biology. 92: 303-15. PMID 24183240 DOI: 10.1016/j.ejcb.2013.09.002  0.34
2013 Glushakov AV, Robbins SW, Bracy CL, Narumiya S, Doré S. Prostaglandin F2α FP receptor antagonist improves outcomes after experimental traumatic brain injury. Journal of Neuroinflammation. 10: 132. PMID 24172576 DOI: 10.1186/1742-2094-10-132  0.34
2013 Sugita K, Ikenouchi-Sugita A, Nakayama Y, Yoshioka H, Nomura T, Sakabe J, Nakahigashi K, Kuroda E, Uematsu S, Nakamura J, Akira S, Nakamura M, Narumiya S, Miyachi Y, Tokura Y, et al. Prostaglandin E₂ is critical for the development of niacin-deficiency-induced photosensitivity via ROS production. Scientific Reports. 3: 2973. PMID 24131900 DOI: 10.1038/srep02973  0.357
2013 Mohan S, Glushakov AV, Decurnou A, Narumiya S, Doré S. Contribution of PGE2 EP1 receptor in hemin-induced neurotoxicity. Frontiers in Molecular Neuroscience. 6: 31. PMID 24109429 DOI: 10.3389/fnmol.2013.00031  0.37
2013 Shiraishi N, Nomura T, Tanizaki H, Nakajima S, Narumiya S, Miyachi Y, Tokura Y, Kabashima K. Prostaglandin E2-EP3 axis in fine-tuning excessive skin inflammation by restricting dendritic cell functions. Plos One. 8: e69599. PMID 23922752 DOI: 10.1371/journal.pone.0069599  0.344
2013 Toyoda Y, Shinohara R, Thumkeo D, Kamijo H, Nishimaru H, Hioki H, Kaneko T, Ishizaki T, Furuyashiki T, Narumiya S. EphA4-dependent axon retraction and midline localization of Ephrin-B3 are disrupted in the spinal cord of mice lacking mDia1 and mDia3 in combination. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 18: 873-85. PMID 23890216 DOI: 10.1111/Gtc.12081  0.571
2013 Ehrlich AT, Furuyashiki T, Kitaoka S, Kakizuka A, Narumiya S. Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(βγ) subunits in human embryonic kidney 293T cells. Molecular Pharmacology. 84: 476-86. PMID 23842570 DOI: 10.1124/Mol.113.087288  0.799
2013 Singh N, Ma B, Leonardo CC, Ahmad AS, Narumiya S, Doré S. Role of PGEâ‚‚ EP1 receptor in intracerebral hemorrhage-induced brain injury. Neurotoxicity Research. 24: 549-59. PMID 23824501 DOI: 10.1007/S12640-013-9410-7  0.383
2013 Taketomi Y, Ueno N, Kojima T, Sato H, Murase R, Yamamoto K, Tanaka S, Sakanaka M, Nakamura M, Nishito Y, Kawana M, Kambe N, Ikeda K, Taguchi R, Nakamizo S, ... ... Narumiya S, et al. Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis. Nature Immunology. 14: 554-63. PMID 23624557 DOI: 10.1038/Ni.2586  0.34
2013 Yao C, Hirata T, Soontrapa K, Ma X, Takemori H, Narumiya S. Prostaglandin Eâ‚‚ promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase. Nature Communications. 4: 1685. PMID 23575689 DOI: 10.1038/ncomms2684  0.355
2013 Murata T, Aritake K, Tsubosaka Y, Maruyama T, Nakagawa T, Hori M, Hirai H, Nakamura M, Narumiya S, Urade Y, Ozaki H. Anti-inflammatory role of PGD2 in acute lung inflammation and therapeutic application of its signal enhancement. Proceedings of the National Academy of Sciences of the United States of America. 110: 5205-10. PMID 23479612 DOI: 10.1073/pnas.1218091110  0.352
2013 Ahmad AS, Maruyama T, Narumiya S, Doré S. PGE2 EP1 receptor deletion attenuates 6-OHDA-induced Parkinsonism in mice: old switch, new target. Neurotoxicity Research. 23: 260-6. PMID 23385625 DOI: 10.1007/S12640-013-9381-8  0.396
2013 Ikushima YM, Arai F, Hosokawa K, Toyama H, Takubo K, Furuyashiki T, Narumiya S, Suda T. Prostaglandin E(2) regulates murine hematopoietic stem/progenitor cells directly via EP4 receptor and indirectly through mesenchymal progenitor cells. Blood. 121: 1995-2007. PMID 23315170 DOI: 10.1182/Blood-2012-06-437889  0.644
2013 Kobayashi K, Tsubosaka Y, Hori M, Narumiya S, Ozaki H, Murata T. Prostaglandin D2-DP signaling promotes endothelial barrier function via the cAMP/PKA/Tiam1/Rac1 pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 565-71. PMID 23307871 DOI: 10.1161/ATVBAHA.112.300993  0.352
2012 Hirata T, Narumiya S. Prostanoids as regulators of innate and adaptive immunity. Advances in Immunology. 116: 143-74. PMID 23063076 DOI: 10.1016/B978-0-12-394300-2.00005-3  0.361
2012 Pöschke A, Kern N, Maruyama T, Pavenstädt H, Narumiya S, Jensen BL, Nüsing RM. The PGE(2)-EP4 receptor is necessary for stimulation of the renin-angiotensin-aldosterone system in response to low dietary salt intake in vivo. American Journal of Physiology. Renal Physiology. 303: F1435-42. PMID 22993066 DOI: 10.1152/ajprenal.00512.2011  0.353
2012 Hirata T, Nomachi A, Tohya K, Miyasaka M, Tsukita S, Watanabe T, Narumiya S. Moesin-deficient mice reveal a non-redundant role for moesin in lymphocyte homeostasis. International Immunology. 24: 705-17. PMID 22875842 DOI: 10.1093/intimm/dxs077  0.324
2012 Guo Y, Tukaye DN, Wu WJ, Zhu X, Book M, Tan W, Jones SP, Rokosh G, Narumiya S, Li Q, Bolli R. The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning. Plos One. 7: e41178. PMID 22844439 DOI: 10.1371/Journal.Pone.0041178  0.369
2012 Kaneko K, Lazarus M, Miyamoto C, Oishi Y, Nagata N, Yang S, Yoshikawa M, Aritake K, Furuyashiki T, Narumiya S, Urade Y, Ohinata K. Orally administered rubiscolin-6, a δ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin D synthase in mice. Molecular Nutrition & Food Research. 56: 1315-23. PMID 22715053 DOI: 10.1002/Mnfr.201200155  0.603
2012 Kim YT, Moon SK, Maruyama T, Narumiya S, Doré S. Prostaglandin FP receptor inhibitor reduces ischemic brain damage and neurotoxicity. Neurobiology of Disease. 48: 58-65. PMID 22709986 DOI: 10.1016/j.nbd.2012.06.003  0.385
2012 Imai K, Ueta M, Mori K, Ueno M, Ikeda Y, Oga T, Yokoi N, Shinomiya K, Narumiya S, Kinoshita S. Expression of prostaglandin F receptor in scleral and subconjunctival tissue. The British Journal of Ophthalmology. 96: 1148-9. PMID 22581279 DOI: 10.1136/bjophthalmol-2012-301815  0.321
2012 Frölich S, Olliges A, Kern N, Schreiber Y, Narumiya S, Nüsing RM. Temporal expression of the PGE2 synthetic system in the kidney is associated with the time frame of renal developmental vulnerability to cyclooxygenase-2 inhibition. American Journal of Physiology. Renal Physiology. 303: F209-19. PMID 22573380 DOI: 10.1152/ajprenal.00418.2011  0.313
2012 Vennemann A, Gerstner A, Kern N, Ferreiros Bouzas N, Narumiya S, Maruyama T, Nüsing RM. PTGS-2-PTGER2/4 signaling pathway partially protects from diabetogenic toxicity of streptozotocin in mice. Diabetes. 61: 1879-87. PMID 22522619 DOI: 10.2337/db11-1396  0.342
2012 Nakagawa N, Yuhki K, Kawabe J, Fujino T, Takahata O, Kabara M, Abe K, Kojima F, Kashiwagi H, Hasebe N, Kikuchi K, Sugimoto Y, Narumiya S, Ushikubi F. The intrinsic prostaglandin E2-EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice. Kidney International. 82: 158-71. PMID 22513820 DOI: 10.1038/ki.2012.115  0.35
2012 Tanaka K, Furuyashiki T, Kitaoka S, Senzai Y, Imoto Y, Segi-Nishida E, Deguchi Y, Breyer RM, Breyer MD, Narumiya S. Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4319-29. PMID 22442093 DOI: 10.1523/Jneurosci.5952-11.2012  0.784
2012 Ueta M, Tamiya G, Tokunaga K, Sotozono C, Ueki M, Sawai H, Inatomi T, Matsuoka T, Akira S, Narumiya S, Tashiro K, Kinoshita S. Epistatic interaction between Toll-like receptor 3 (TLR3) and prostaglandin E receptor 3 (PTGER3) genes. The Journal of Allergy and Clinical Immunology. 129: 1413-1416.e11. PMID 22421267 DOI: 10.1016/j.jaci.2012.01.069  0.35
2012 Matsui Y, Amano H, Ito Y, Eshima K, Suzuki T, Ogawa F, Iyoda A, Satoh Y, Kato S, Nakamura M, Kitasato H, Narumiya S, Majima M. Thromboxane Aâ‚‚ receptor signaling facilitates tumor colonization through P-selectin-mediated interaction of tumor cells with platelets and endothelial cells. Cancer Science. 103: 700-7. PMID 22296266 DOI: 10.1111/j.1349-7006.2012.02200.x  0.329
2012 Shinohara R, Thumkeo D, Kamijo H, Kaneko N, Sawamoto K, Watanabe K, Takebayashi H, Kiyonari H, Ishizaki T, Furuyashiki T, Narumiya S. A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors. Nature Neuroscience. 15: 373-80, S1-2. PMID 22246438 DOI: 10.1038/Nn.3020  0.598
2012 Minamino T, Ito Y, Ohkubo H, Hosono K, Suzuki T, Sato T, Ae T, Shibuya A, Sakagami H, Narumiya S, Koizumi W, Majima M. Thromboxane A(2) receptor signaling promotes liver tissue repair after toxic injury through the enhancement of macrophage recruitment. Toxicology and Applied Pharmacology. 259: 104-14. PMID 22206755 DOI: 10.1016/j.taap.2011.12.013  0.348
2012 Hamaguchi K, Yamamoto N, Nakagawa T, Furuyashiki T, Narumiya S, Ito J. Role of PGE-type receptor 4 in auditory function and noise-induced hearing loss in mice. Neuropharmacology. 62: 1841-7. PMID 22198478 DOI: 10.1016/J.Neuropharm.2011.12.007  0.597
2012 Tajima T, Murata T, Aritake K, Urade Y, Michishita M, Matsuoka T, Narumiya S, Ozaki H, Hori M. EP2 and EP4 receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G524-34. PMID 22159280 DOI: 10.1152/ajpgi.00264.2011  0.33
2012 Hoshino T, Namba T, Takehara M, Murao N, Matsushima T, Sugimoto Y, Narumiya S, Suzuki T, Mizushima T. Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor. Journal of Neurochemistry. 120: 795-805. PMID 22044482 DOI: 10.1111/J.1471-4159.2011.07567.X  0.397
2012 Zhen G, Kim YT, Li RC, Yocum J, Kapoor N, Langer J, Dobrowolski P, Maruyama T, Narumiya S, Doré S. PGE2 EP1 receptor exacerbated neurotoxicity in a mouse model of cerebral ischemia and Alzheimer's disease. Neurobiology of Aging. 33: 2215-9. PMID 22015313 DOI: 10.1016/j.neurobiolaging.2011.09.017  0.329
2012 Minamino T, Ito Y, Ohkubo H, Hidaka H, Shibuya A, Koizumi W, Narumiya S, Majima M. 425 Role Of Thromboxanea2 Receptor Signaling In Liver Repair After Hepatotoxicity Journal of Hepatology. 56. DOI: 10.1016/S0168-8278(12)60438-3  0.306
2011 Thumkeo D, Shinohara R, Watanabe K, Takebayashi H, Toyoda Y, Tohyama K, Ishizaki T, Furuyashiki T, Narumiya S. Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia. Plos One. 6: e25465. PMID 21980468 DOI: 10.1371/Journal.Pone.0025465  0.594
2011 Kamijo H, Matsumura Y, Thumkeo D, Koike S, Masu M, Shimizu Y, Ishizaki T, Narumiya S. Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK-I and ROCK-II. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 16: 1012-21. PMID 21895889 DOI: 10.1111/j.1365-2443.2011.01546.x  0.305
2011 Ikeda-Matsuo Y, Tanji H, Narumiya S, Sasaki Y. Inhibition of prostaglandin E2 EP3 receptors improves stroke injury via anti-inflammatory and anti-apoptotic mechanisms. Journal of Neuroimmunology. 238: 34-43. PMID 21803432 DOI: 10.1016/j.jneuroim.2011.06.014  0.367
2011 Woodward DF, Jones RL, Narumiya S. International Union of Basic and Clinical Pharmacology. LXXXIII: classification of prostanoid receptors, updating 15 years of progress. Pharmacological Reviews. 63: 471-538. PMID 21752876 DOI: 10.1124/pr.110.003517  0.358
2011 Mitsumori T, Furuyashiki T, Momiyama T, Nishi A, Shuto T, Hayakawa T, Ushikubi F, Kitaoka S, Aoki T, Inoue H, Matsuoka T, Narumiya S. Thromboxane receptor activation enhances striatal dopamine release, leading to suppression of GABAergic transmission and enhanced sugar intake. The European Journal of Neuroscience. 34: 594-604. PMID 21749493 DOI: 10.1111/J.1460-9568.2011.07774.X  0.603
2011 Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T. Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2. The American Journal of Pathology. 179: 302-14. PMID 21703412 DOI: 10.1016/j.ajpath.2011.03.047  0.362
2011 Suzuki C, Miyamoto C, Furuyashiki T, Narumiya S, Ohinata K. Central PGE2 exhibits anxiolytic-like activity via EP1 and EP4 receptors in a manner dependent on serotonin 5-HT1A, dopamine D1 and GABAA receptors. Febs Letters. 585: 2357-62. PMID 21693121 DOI: 10.1016/J.Febslet.2011.06.004  0.634
2011 Fujita T, Matsuoka T, Honda T, Kabashima K, Hirata T, Narumiya S. A GPR40 agonist GW9508 suppresses CCL5, CCL17, and CXCL10 induction in keratinocytes and attenuates cutaneous immune inflammation. The Journal of Investigative Dermatology. 131: 1660-7. PMID 21593768 DOI: 10.1038/jid.2011.123  0.332
2011 Soontrapa K, Honda T, Sakata D, Yao C, Hirata T, Hori S, Matsuoka T, Kita Y, Shimizu T, Kabashima K, Narumiya S. Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression. Proceedings of the National Academy of Sciences of the United States of America. 108: 6668-73. PMID 21460251 DOI: 10.1073/Pnas.1018625108  0.42
2011 Johansson T, Narumiya S, Zeilhofer HU. Contribution of peripheral versus central EP1 prostaglandin receptors to inflammatory pain. Neuroscience Letters. 495: 98-101. PMID 21440042 DOI: 10.1016/j.neulet.2011.03.046  0.368
2011 Aoki T, Nishimura M, Matsuoka T, Yamamoto K, Furuyashiki T, Kataoka H, Kitaoka S, Ishibashi R, Ishibazawa A, Miyamoto S, Morishita R, Ando J, Hashimoto N, Nozaki K, Narumiya S. PGE(2) -EP(2) signalling in endothelium is activated by haemodynamic stress and induces cerebral aneurysm through an amplifying loop via NF-κB. British Journal of Pharmacology. 163: 1237-49. PMID 21426319 DOI: 10.1111/J.1476-5381.2011.01358.X  0.606
2011 Narumiya S, Furuyashiki T. Fever, inflammation, pain and beyond: prostanoid receptor research during these 25 years. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 813-8. PMID 21357250 DOI: 10.1096/Fj.11-0302Ufm  0.561
2011 Hosono K, Suzuki T, Tamaki H, Sakagami H, Hayashi I, Narumiya S, Alitalo K, Majima M. Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1049-58. PMID 21311040 DOI: 10.1161/Atvbaha.110.222356  0.367
2011 Eguchi M, Kariya S, Okano M, Higaki T, Makihara S, Fujiwara T, Nagata K, Hirai H, Narumiya S, Nakamura M, Nishizaki K. Lipopolysaccharide induces proinflammatory cytokines and chemokines in experimental otitis media through the prostaglandin D2 receptor (DP)-dependent pathway. Clinical and Experimental Immunology. 163: 260-9. PMID 21166666 DOI: 10.1111/j.1365-2249.2010.04292.x  0.387
2011 Furuyashiki T, Narumiya S. Stress responses: the contribution of prostaglandin E(2) and its receptors. Nature Reviews. Endocrinology. 7: 163-75. PMID 21116297 DOI: 10.1038/Nrendo.2010.194  0.623
2011 Yuhki K, Kojima F, Kashiwagi H, Kawabe J, Fujino T, Narumiya S, Ushikubi F. Roles of prostanoids in the pathogenesis of cardiovascular diseases: Novel insights from knockout mouse studies. Pharmacology & Therapeutics. 129: 195-205. PMID 20920529 DOI: 10.1016/j.pharmthera.2010.09.004  0.398
2011 Tanaka K, Kitaoka S, Senzai Y, Furuyashiki T, Narumiya S. Prostaglandin E receptor EP1 is critical for social withdrawal and the plasticity of dopaminergic neurons after repeated social defeat Neuroscience Research. 71: e167. DOI: 10.1016/J.Neures.2011.07.721  0.779
2011 Shinohara R, Thumkeo D, Kamijo H, Kaneko N, Sawamoto K, Watanabe K, Takebayashi H, Kiyonari H, Ishizaki T, Furuyashiki T, Narumiya S. mDia, an actin nucleator and a Rho effector, is critical for tangential migration of cortical and olfactory bulb inhibitory interneuron precursors Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.556  0.551
2011 Furuyashiki T, Tanaka K, Kitaoka S, Senzai Y, Narumiya S. Prostaglandin E2-mediated desensitization of mesocortical dopamine neurons is critical for susceptibility to repeated social defeat stress Neuroscience Research. 71: e52. DOI: 10.1016/J.Neures.2011.07.219  0.778
2010 Tanji M, Ishizaki T, Ebrahimi S, Tsuboguchi Y, Sukezane T, Akagi T, Frame MC, Hashimoto N, Miyamoto S, Narumiya S. mDia1 targets v-Src to the cell periphery and facilitates cell transformation, tumorigenesis, and invasion. Molecular and Cellular Biology. 30: 4604-15. PMID 20679479 DOI: 10.1128/MCB.00197-10  0.336
2010 Sakata D, Yao C, Narumiya S. Emerging roles of prostanoids in T cell-mediated immunity. Iubmb Life. 62: 591-6. PMID 20665621 DOI: 10.1002/iub.356  0.376
2010 Ahmad AS, Ahmad M, Maruyama T, Narumiya S, Doré S. Prostaglandin D2 DP1 receptor is beneficial in ischemic stroke and in acute exicitotoxicity in young and old mice. Age (Dordrecht, Netherlands). 32: 271-82. PMID 20640551 DOI: 10.1007/S11357-010-9135-Y  0.35
2010 Saleem S, Shah ZA, Maruyama T, Narumiya S, Doré S. Neuroprotective properties of prostaglandin I2 IP receptor in focal cerebral ischemia. Neuroscience. 170: 317-23. PMID 20621166 DOI: 10.1016/J.Neuroscience.2010.06.060  0.343
2010 Ahmad M, Saleem S, Shah Z, Maruyama T, Narumiya S, Doré S. The PGE2 EP2 receptor and its selective activation are beneficial against ischemic stroke. Experimental & Translational Stroke Medicine. 2: 12. PMID 20615245 DOI: 10.1186/2040-7378-2-12  0.346
2010 Esaki Y, Li Y, Sakata D, Yao C, Segi-Nishida E, Matsuoka T, Fukuda K, Narumiya S. Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 107: 12233-8. PMID 20566843 DOI: 10.1073/pnas.0915112107  0.713
2010 Chan EC, Dusting GJ, Guo N, Peshavariya HM, Taylor CJ, Dilley R, Narumiya S, Jiang F. Prostacyclin receptor suppresses cardiac fibrosis: role of CREB phosphorylation. Journal of Molecular and Cellular Cardiology. 49: 176-85. PMID 20403362 DOI: 10.1016/j.yjmcc.2010.04.006  0.336
2010 Nakajima S, Honda T, Sakata D, Egawa G, Tanizaki H, Otsuka A, Moniaga CS, Watanabe T, Miyachi Y, Narumiya S, Kabashima K. Prostaglandin I2-IP signaling promotes Th1 differentiation in a mouse model of contact hypersensitivity. Journal of Immunology (Baltimore, Md. : 1950). 184: 5595-603. PMID 20400695 DOI: 10.4049/jimmunol.0903260  0.362
2010 Tamba S, Yodoi R, Morimoto K, Inazumi T, Sukeno M, Segi-Nishida E, Okuno Y, Tsujimoto G, Narumiya S, Sugimoto Y. Expression profiling of cumulus cells reveals functional changes during ovulation and central roles of prostaglandin EP2 receptor in cAMP signaling. Biochimie. 92: 665-75. PMID 20399827 DOI: 10.1016/j.biochi.2010.04.006  0.691
2010 Katoh H, Hosono K, Ito Y, Suzuki T, Ogawa Y, Kubo H, Kamata H, Mishima T, Tamaki H, Sakagami H, Sugimoto Y, Narumiya S, Watanabe M, Majima M. COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems. The American Journal of Pathology. 176: 1469-83. PMID 20110411 DOI: 10.2353/ajpath.2010.090607  0.326
2010 Sakata D, Yao C, Narumiya S. Prostaglandin E2, an immunoactivator. Journal of Pharmacological Sciences. 112: 1-5. PMID 20051652 DOI: JST.JSTAGE/jphs/09R03CP  0.352
2010 Kubo H, Hosono K, Suzuki T, Ogawa Y, Kato H, Kamata H, Ito Y, Amano H, Kato T, Sakagami H, Hayashi I, Sugimoto Y, Narumiya S, Watanabe M, Majima M. Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis. Biomedicine & Pharmacotherapy = Biomã©Decine & Pharmacothã©Rapie. 64: 101-6. PMID 20034758 DOI: 10.1016/j.biopha.2009.04.039  0.362
2010 Ueno T, Suzuki T, Oikawa A, Hosono K, Kosaka Y, Amano H, Kitasato H, Toda M, Hayashi I, Kato T, Ito Y, Sugimoto Y, Narumiya S, Okamoto H, Majima M. Recruited bone marrow cells expressing the EP3 prostaglandin E receptor subtype enhance angiogenesis during chronic inflammation. Biomedicine & Pharmacotherapy = Biomã©Decine & Pharmacothã©Rapie. 64: 93-100. PMID 20015609 DOI: 10.1016/j.biopha.2009.04.034  0.374
2010 Kawabe J, Yuhki K, Okada M, Kanno T, Yamauchi A, Tashiro N, Sasaki T, Okumura S, Nakagawa N, Aburakawa Y, Takehara N, Fujino T, Hasebe N, Narumiya S, Ushikubi F. Prostaglandin I2 promotes recruitment of endothelial progenitor cells and limits vascular remodeling. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 464-70. PMID 20007911 DOI: 10.1161/ATVBAHA.109.193730  0.352
2010 Furuyashiki T, Tanaka K, Kitaoka S, Narumiya S. Roles of prostaglandin E2, a proinflammatory mediator, in emotional adaptation to stress Neuroscience Research. 68: e47. DOI: 10.1016/J.Neures.2010.07.455  0.563
2010 Tanaka K, Kitaoka S, Furuyashiki T, Narumiya S. Roles of prostaglandin E2 and its receptor EP1 in social withdrawal after repeated social defeat in mice Neuroscience Research. 68: e171. DOI: 10.1016/J.Neures.2010.07.2331  0.612
2010 Shinohara R, Thumkeo D, Kamijo H, Kaneko N, Sawamoto K, Hioki H, Kaneko T, Watanabe K, Takebayashi H, Ishizaki T, Furuyashiki T, Narumiya S. Roles of mDia isoforms, a Rho effector, in neural development Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.2184  0.549
2010 Ehrlich AT, Furuyashiki T, Kitaoka S, Narumiya S. Prostaglandin E receptor EP1 induces intracellular accumulation of dopamine D1 receptor and facilitates dopamine D1 receptor signaling in a Ca2+-independent manner Neuroscience Research. 68: e121. DOI: 10.1016/J.Neures.2010.07.2104  0.795
2010 Aoki T, Furuyashiki T, Takatsuki A, Seiyama A, Narumiya S. Roles of prostaglandin E2-EP4 signaling in functional hyperemia in the brain Neuroscience Research. 68: e355. DOI: 10.1016/J.Neures.2010.07.1574  0.564
2010 Mitsumori T, Furuyashiki T, Kitaoka S, Inoue H, Matsuoka T, Narumiya S. Roles of thromboxane receptor in dopaminergic signaling in the striatum Neuroscience Research. 68: e235. DOI: 10.1016/J.Neures.2010.07.1041  0.615
2009 Tanaka Y, Furuyashiki T, Momiyama T, Namba H, Mizoguchi A, Mitsumori T, Kayahara T, Shichi H, Kimura K, Matsuoka T, Nawa H, Narumiya S. Prostaglandin E receptor EP1 enhances GABA-mediated inhibition of dopaminergic neurons in the substantia nigra pars compacta and regulates dopamine level in the dorsal striatum. The European Journal of Neuroscience. 30: 2338-46. PMID 20092576 DOI: 10.1111/J.1460-9568.2009.07021.X  0.632
2009 Hanada R, Leibbrandt A, Hanada T, Kitaoka S, Furuyashiki T, Fujihara H, Trichereau J, Paolino M, Qadri F, Plehm R, Klaere S, Komnenovic V, Mimata H, Yoshimatsu H, Takahashi N, ... ... Narumiya S, et al. Central control of fever and female body temperature by RANKL/RANK. Nature. 462: 505-9. PMID 19940926 DOI: 10.1038/Nature08596  0.615
2009 Amano H, Ito Y, Suzuki T, Kato S, Matsui Y, Ogawa F, Murata T, Sugimoto Y, Senior R, Kitasato H, Hayashi I, Satoh Y, Narumiya S, Majima M. Roles of a prostaglandin E-type receptor, EP3, in upregulation of matrix metalloproteinase-9 and vascular endothelial growth factor during enhancement of tumor metastasis. Cancer Science. 100: 2318-24. PMID 19799610 DOI: 10.1111/j.1349-7006.2009.01322.x  0.363
2009 Narumiya S. Prostanoids and inflammation: a new concept arising from receptor knockout mice. Journal of Molecular Medicine (Berlin, Germany). 87: 1015-22. PMID 19609495 DOI: 10.1007/s00109-009-0500-1  0.403
2009 Honda T, Matsuoka T, Ueta M, Kabashima K, Miyachi Y, Narumiya S. Prostaglandin E(2)-EP(3) signaling suppresses skin inflammation in murine contact hypersensitivity. The Journal of Allergy and Clinical Immunology. 124: 809-18.e2. PMID 19541354 DOI: 10.1016/j.jaci.2009.04.029  0.364
2009 Yao C, Sakata D, Esaki Y, Li Y, Matsuoka T, Kuroiwa K, Sugimoto Y, Narumiya S. Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion. Nature Medicine. 15: 633-40. PMID 19465928 DOI: 10.1038/nm.1968  0.31
2009 Hoshino T, Namba T, Takehara M, Nakaya T, Sugimoto Y, Araki W, Narumiya S, Suzuki T, Mizushima T. Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor. The Journal of Biological Chemistry. 284: 18493-502. PMID 19407341 DOI: 10.1074/Jbc.M109.003269  0.389
2009 Saleem S, Ahmad AS, Maruyama T, Narumiya S, Doré S. PGF(2alpha) FP receptor contributes to brain damage following transient focal brain ischemia. Neurotoxicity Research. 15: 62-70. PMID 19384589 DOI: 10.1007/S12640-009-9007-3  0.336
2009 Yodoi R, Tamba S, Morimoto K, Segi-Nishida E, Nishihara M, Ichikawa A, Narumiya S, Sugimoto Y. RhoA/Rho kinase signaling in the cumulus mediates extracellular matrix assembly. Endocrinology. 150: 3345-52. PMID 19342461 DOI: 10.1210/en.2008-1449  0.691
2009 Ogawa Y, Suzuki T, Oikawa A, Hosono K, Kubo H, Amano H, Ito Y, Kitasato H, Hayashi I, Kato T, Sugimoto Y, Narumiya S, Watanabe M, Majima M. Bone marrow-derived EP3-expressing stromal cells enhance tumor-associated angiogenesis and tumor growth. Biochemical and Biophysical Research Communications. 382: 720-5. PMID 19318087 DOI: 10.1016/j.bbrc.2009.03.094  0.336
2009 Monypenny J, Zicha D, Higashida C, Oceguera-Yanez F, Narumiya S, Watanabe N. Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis. Molecular and Cellular Biology. 29: 2730-47. PMID 19273601 DOI: 10.1128/MCB.01285-08  0.31
2009 Saleem S, Kim YT, Maruyama T, Narumiya S, Doré S. Reduced acute brain injury in PGE2 EP3 receptor-deficient mice after cerebral ischemia. Journal of Neuroimmunology. 208: 87-93. PMID 19203800 DOI: 10.1016/J.Jneuroim.2009.01.015  0.323
2009 Narumiya S, Tanji M, Ishizaki T. Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion. Cancer Metastasis Reviews. 28: 65-76. PMID 19160018 DOI: 10.1007/s10555-008-9170-7  0.324
2009 Furuyashiki T, Narumiya S. Roles of prostaglandin E receptors in stress responses. Current Opinion in Pharmacology. 9: 31-8. PMID 19157987 DOI: 10.1016/J.Coph.2008.12.010  0.62
2009 Ueta M, Matsuoka T, Narumiya S, Kinoshita S. Prostaglandin E receptor subtype EP3 in conjunctival epithelium regulates late-phase reaction of experimental allergic conjunctivitis. The Journal of Allergy and Clinical Immunology. 123: 466-71. PMID 18996575 DOI: 10.1016/j.jaci.2008.09.044  0.38
2009 Popp L, Häussler A, Olliges A, Nüsing R, Narumiya S, Geisslinger G, Tegeder I. Comparison of nociceptive behavior in prostaglandin E, F, D, prostacyclin and thromboxane receptor knockout mice. European Journal of Pain (London, England). 13: 691-703. PMID 18938093 DOI: 10.1016/j.ejpain.2008.09.001  0.367
2009 Fujita A, Shishido T, Yuan Y, Inamoto E, Narumiya S, Watanabe N. Imatinib mesylate (STI571)-induced cell edge translocation of kinase-active and kinase-defective Abelson kinase: requirements of myristoylation and src homology 3 domain. Molecular Pharmacology. 75: 75-84. PMID 18835981 DOI: 10.1124/mol.108.051706  0.301
2009 Shinohara R, Kamijo H, Hioki H, Kaneko T, Ishizaki T, Furuyashiki T, Narumiya S. Roles of mDia, a Rho effector, in neural development Neuroscience Research. 65: S95. DOI: 10.1016/J.Neures.2009.09.403  0.545
2008 Murata T, Lin MI, Aritake K, Matsumoto S, Narumiya S, Ozaki H, Urade Y, Hori M, Sessa WC. Role of prostaglandin D2 receptor DP as a suppressor of tumor hyperpermeability and angiogenesis in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 20009-14. PMID 19060214 DOI: 10.1073/Pnas.0805171105  0.337
2008 Katagiri H, Ito Y, Ito S, Murata T, Yukihiko S, Narumiya S, Watanabe M, Majima M. TNF-alpha induces thromboxane receptor signaling-dependent microcirculatory dysfunction in mouse liver. Shock (Augusta, Ga.). 30: 463-7. PMID 18800000 DOI: 10.1097/SHK.0b013e3181673f54  0.323
2008 Tamba S, Yodoi R, Segi-Nishida E, Ichikawa A, Narumiya S, Sugimoto Y. Timely interaction between prostaglandin and chemokine signaling is a prerequisite for successful fertilization. Proceedings of the National Academy of Sciences of the United States of America. 105: 14539-44. PMID 18794532 DOI: 10.1073/pnas.0805699105  0.69
2008 Wei G, Kibler KK, Koehler RC, Maruyama T, Narumiya S, Doré S. Prostacyclin receptor deletion aggravates hippocampal neuronal loss after bilateral common carotid artery occlusion in mouse. Neuroscience. 156: 1111-7. PMID 18790018 DOI: 10.1016/j.neuroscience.2008.07.073  0.354
2008 Matsuoka T, Narumiya S. The roles of prostanoids in infection and sickness behaviors. Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy. 14: 270-8. PMID 18709530 DOI: 10.1007/s10156-008-0622-3  0.406
2008 Wang X, Momota Y, Yanase H, Narumiya S, Maruyama T, Kawatani M. Urothelium EP1 receptor facilitates the micturition reflex in mice. Biomedical Research (Tokyo, Japan). 29: 105-11. PMID 18480552 DOI: 10.2220/biomedres.29.105  0.397
2008 Yuhki K, Ushikubi F, Naraba H, Ueno A, Kato H, Kojima F, Narumiya S, Sugimoto Y, Matsushita M, Oh-Ishi S. Prostaglandin I2 plays a key role in zymosan-induced mouse pleurisy. The Journal of Pharmacology and Experimental Therapeutics. 325: 601-9. PMID 18256172 DOI: 10.1124/jpet.107.134494  0.382
2008 Takeya R, Taniguchi K, Narumiya S, Sumimoto H. The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells. The Embo Journal. 27: 618-28. PMID 18239683 DOI: 10.1038/emboj.2008.7  0.327
2008 Torres D, Paget C, Fontaine J, Mallevaey T, Matsuoka T, Maruyama T, Narumiya S, Capron M, Gosset P, Faveeuw C, Trottein F. Prostaglandin D2 inhibits the production of IFN-gamma by invariant NK T cells: consequences in the control of B16 melanoma. Journal of Immunology (Baltimore, Md. : 1950). 180: 783-92. PMID 18178816 DOI: 10.4049/Jimmunol.180.2.783  0.329
2008 Matsuoka T, Narumiya S. The roles of prostanoids in inflammation, allergy, and immunity Inflammation and Regeneration. 28: 423-433. DOI: 10.2492/Inflammregen.28.423  0.403
2007 Kitaoka S, Furuyashiki T, Nishi A, Shuto T, Koyasu S, Matsuoka T, Miyasaka M, Greengard P, Narumiya S. Prostaglandin E2 acts on EP1 receptor and amplifies both dopamine D1 and D2 receptor signaling in the striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12900-7. PMID 18032663 DOI: 10.1523/Jneurosci.3257-07.2007  0.624
2007 Nagamachi M, Sakata D, Kabashima K, Furuyashiki T, Murata T, Segi-Nishida E, Soontrapa K, Matsuoka T, Miyachi Y, Narumiya S. Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1. The Journal of Experimental Medicine. 204: 2865-74. PMID 17967902 DOI: 10.1084/Jem.20070773  0.775
2007 Matsuoka T, Narumiya S. Prostaglandin receptor signaling in disease. Thescientificworldjournal. 7: 1329-47. PMID 17767353 DOI: 10.1100/tsw.2007.182  0.395
2007 Hoshino T, Nakaya T, Homan T, Tanaka K, Sugimoto Y, Araki W, Narita M, Narumiya S, Suzuki T, Mizushima T. Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo. The Journal of Biological Chemistry. 282: 32676-88. PMID 17767011 DOI: 10.1074/Jbc.M703087200  0.329
2007 Gopinath SD, Narumiya S, Dhawan J. The RhoA effector mDiaphanous regulates MyoD expression and cell cycle progression via SRF-dependent and SRF-independent pathways. Journal of Cell Science. 120: 3086-98. PMID 17684061 DOI: 10.1242/jcs.006619  0.307
2007 Sakata D, Taniguchi H, Yasuda S, Adachi-Morishima A, Hamazaki Y, Nakayama R, Miki T, Minato N, Narumiya S. Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1. The Journal of Experimental Medicine. 204: 2031-8. PMID 17682067 DOI: 10.1084/jem.20062647  0.339
2007 Noguchi M, Hosoda K, Fujikura J, Fujimoto M, Iwakura H, Tomita T, Ishii T, Arai N, Hirata M, Ebihara K, Masuzaki H, Itoh H, Narumiya S, Nakao K. Genetic and pharmacological inhibition of Rho-associated kinase II enhances adipogenesis. The Journal of Biological Chemistry. 282: 29574-83. PMID 17681946 DOI: 10.1074/jbc.M705972200  0.305
2007 Hristovska AM, Rasmussen LE, Hansen PB, Nielsen SS, Nüsing RM, Narumiya S, Vanhoutte P, Skøtt O, Jensen BL. Prostaglandin E2 induces vascular relaxation by E-prostanoid 4 receptor-mediated activation of endothelial nitric oxide synthase. Hypertension. 50: 525-30. PMID 17635857 DOI: 10.1161/HYPERTENSIONAHA.107.088948  0.367
2007 Saleem S, Zhuang H, de Brum-Fernandes AJ, Maruyama T, Narumiya S, Doré S. PGD(2) DP1 receptor protects brain from ischemia-reperfusion injury. The European Journal of Neuroscience. 26: 73-8. PMID 17573924 DOI: 10.1111/J.1460-9568.2007.05627.X  0.343
2007 Taniguchi H, Mohri I, Okabe-Arahori H, Aritake K, Wada K, Kanekiyo T, Narumiya S, Nakayama M, Ozono K, Urade Y, Taniike M. Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4303-12. PMID 17442814 DOI: 10.1523/JNEUROSCI.0321-07.2007  0.33
2007 Sugimoto Y, Narumiya S. Prostaglandin E receptors. The Journal of Biological Chemistry. 282: 11613-7. PMID 17329241 DOI: 10.1074/jbc.R600038200  0.403
2007 Hammad H, Kool M, Soullié T, Narumiya S, Trottein F, Hoogsteden HC, Lambrecht BN. Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. The Journal of Experimental Medicine. 204: 357-67. PMID 17283205 DOI: 10.1084/jem.20061196  0.36
2007 Ahmad M, Ahmad AS, Zhuang H, Maruyama T, Narumiya S, Doré S. Stimulation of prostaglandin E2-EP3 receptors exacerbates stroke and excitotoxic injury. Journal of Neuroimmunology. 184: 172-9. PMID 17275922 DOI: 10.1016/J.Jneuroim.2006.12.012  0.347
2007 Ota T, Aihara M, Saeki T, Narumiya S, Araie M. The IOP-lowering effects and mechanism of action of tafluprost in prostanoid receptor-deficient mice. The British Journal of Ophthalmology. 91: 673-6. PMID 17124244 DOI: 10.1136/bjo.2006.105585  0.371
2007 Kabashima K, Nagamachi M, Honda T, Nishigori C, Miyachi Y, Tokura Y, Narumiya S. Prostaglandin E2 is required for ultraviolet B-induced skin inflammation via EP2 and EP4 receptors. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 49-55. PMID 17075575 DOI: 10.1038/labinvest.3700491  0.365
2007 Biswas S, Bhattacherjee P, Paterson CA, Maruyama T, Narumiya S. Modulation of ocular inflammatory responses by EP1 receptors in mice. Experimental Eye Research. 84: 39-43. PMID 17052707 DOI: 10.1016/j.exer.2006.08.013  0.4
2006 Zhuge X, Arai H, Xu Y, Murayama T, Kobayashi T, Narumiya S, Kita T, Yokode M. Protection of atherogenesis in thromboxane A2 receptor-deficient mice is not associated with thromboxane A2 receptor in bone marrow-derived cells. Biochemical and Biophysical Research Communications. 351: 865-71. PMID 17097058 DOI: 10.1016/j.bbrc.2006.10.121  0.336
2006 Qu WM, Huang ZL, Xu XH, Aritake K, Eguchi N, Nambu F, Narumiya S, Urade Y, Hayaishi O. Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep. Proceedings of the National Academy of Sciences of the United States of America. 103: 17949-54. PMID 17093043 DOI: 10.1073/pnas.0608581103  0.459
2006 Yang L, Huang Y, Porta R, Yanagisawa K, Gonzalez A, Segi E, Johnson DH, Narumiya S, Carbone DP. Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism. Cancer Research. 66: 9665-72. PMID 17018624 DOI: 10.1158/0008-5472.CAN-06-1271  0.34
2006 Kamoshita E, Ikeda Y, Fujita M, Amano H, Oikawa A, Suzuki T, Ogawa Y, Yamashina S, Azuma S, Narumiya S, Unno N, Majima M. Recruitment of a prostaglandin E receptor subtype, EP3-expressing bone marrow cells is crucial in wound-induced angiogenesis. The American Journal of Pathology. 169: 1458-72. PMID 17003499 DOI: 10.2353/ajpath.2006.051358  0.345
2006 Yamana N, Arakawa Y, Nishino T, Kurokawa K, Tanji M, Itoh RE, Monypenny J, Ishizaki T, Bito H, Nozaki K, Hashimoto N, Matsuda M, Narumiya S. The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src. Molecular and Cellular Biology. 26: 6844-58. PMID 16943426 DOI: 10.1128/Mcb.00283-06  0.301
2006 Ota T, Aihara M, Saeki T, Narumiya S, Araie M. The effects of prostaglandin analogues on prostanoid EP1, EP2, and EP3 receptor-deficient mice. Investigative Ophthalmology & Visual Science. 47: 3395-9. PMID 16877408 DOI: 10.1167/iovs.06-0100  0.394
2006 Hösl K, Reinold H, Harvey RJ, Müller U, Narumiya S, Zeilhofer HU. Spinal prostaglandin E receptors of the EP2 subtype and the glycine receptor alpha3 subunit, which mediate central inflammatory hyperalgesia, do not contribute to pain after peripheral nerve injury or formalin injection. Pain. 126: 46-53. PMID 16846696 DOI: 10.1016/j.pain.2006.06.011  0.362
2006 Ohmae S, Takemoto-Kimura S, Okamura M, Adachi-Morishima A, Nonaka M, Fuse T, Kida S, Tanji M, Furuyashiki T, Arakawa Y, Narumiya S, Okuno H, Bito H. Molecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IV. The Journal of Biological Chemistry. 281: 20427-39. PMID 16684769 DOI: 10.1074/Jbc.M513212200  0.571
2006 Mohri I, Taniike M, Taniguchi H, Kanekiyo T, Aritake K, Inui T, Fukumoto N, Eguchi N, Kushi A, Sasai H, Kanaoka Y, Ozono K, Narumiya S, Suzuki K, Urade Y. Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4383-93. PMID 16624958 DOI: 10.1523/Jneurosci.4531-05.2006  0.411
2006 Honda T, Segi-Nishida E, Miyachi Y, Narumiya S. Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis. The Journal of Experimental Medicine. 203: 325-35. PMID 16446378 DOI: 10.1084/jem.20051310  0.705
2005 Ota T, Aihara M, Narumiya S, Araie M. The effects of prostaglandin analogues on IOP in prostanoid FP-receptor-deficient mice. Investigative Ophthalmology & Visual Science. 46: 4159-63. PMID 16249494 DOI: 10.1167/iovs.05-0494  0.33
2005 Matsuoka Y, Furuyashiki T, Yamada K, Nagai T, Bito H, Tanaka Y, Kitaoka S, Ushikubi F, Nabeshima T, Narumiya S. Prostaglandin E receptor EP1 controls impulsive behavior under stress. Proceedings of the National Academy of Sciences of the United States of America. 102: 16066-71. PMID 16247016 DOI: 10.1073/Pnas.0504908102  0.621
2005 Shoji Y, Takahashi M, Takasuka N, Niho N, Kitamura T, Sato H, Maruyama T, Sugimoto Y, Narumiya S, Sugimura T, Wakabayashi K. Prostaglandin E receptor EP3 deficiency modifies tumor outcome in mouse two-stage skin carcinogenesis. Carcinogenesis. 26: 2116-22. PMID 16051640 DOI: 10.1093/carcin/bgi193  0.362
2005 Ito H, Iwamoto I, Morishita R, Nozawa Y, Narumiya S, Asano T, Nagata K. Possible role of Rho/Rhotekin signaling in mammalian septin organization. Oncogene. 24: 7064-72. PMID 16007136 DOI: 10.1038/sj.onc.1208862  0.321
2005 Nüsing RM, Treude A, Weissenberger C, Jensen B, Bek M, Wagner C, Narumiya S, Seyberth HW. Dominant role of prostaglandin E2 EP4 receptor in furosemide-induced salt-losing tubulopathy: a model for hyperprostaglandin E syndrome/antenatal Bartter syndrome. Journal of the American Society of Nephrology : Jasn. 16: 2354-62. PMID 15976003 DOI: 10.1681/ASN.2004070556  0.407
2005 Takayama K, Yuhki K, Ono K, Fujino T, Hara A, Yamada T, Kuriyama S, Karibe H, Okada Y, Takahata O, Taniguchi T, Iijima T, Iwasaki H, Narumiya S, Ushikubi F. Thromboxane A2 and prostaglandin F2alpha mediate inflammatory tachycardia. Nature Medicine. 11: 562-6. PMID 15834430 DOI: 10.1038/nm1231  0.389
2005 Moriyama T, Higashi T, Togashi K, Iida T, Segi E, Sugimoto Y, Tominaga T, Narumiya S, Tominaga M. Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins. Molecular Pain. 1: 3. PMID 15813989 DOI: 10.1186/1744-8069-1-3  0.421
2005 Kunikata T, Yamane H, Segi E, Matsuoka T, Sugimoto Y, Tanaka S, Tanaka H, Nagai H, Ichikawa A, Narumiya S. Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3. Nature Immunology. 6: 524-31. PMID 15806106 DOI: 10.1038/ni1188  0.411
2005 Riol-Blanco L, Sánchez-Sánchez N, Torres A, Tejedor A, Narumiya S, Corbí AL, Sánchez-Mateos P, Rodríguez-Fernández JL. The chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speed. Journal of Immunology (Baltimore, Md. : 1950). 174: 4070-80. PMID 15778365 DOI: 10.4049/Jimmunol.174.7.4070  0.315
2005 Shimizu Y, Thumkeo D, Keel J, Ishizaki T, Oshima H, Oshima M, Noda Y, Matsumura F, Taketo MM, Narumiya S. ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles. The Journal of Cell Biology. 168: 941-53. PMID 15753128 DOI: 10.1083/jcb.200411179  0.324
2005 Reinold H, Ahmadi S, Depner UB, Layh B, Heindl C, Hamza M, Pahl A, Brune K, Narumiya S, Müller U, Zeilhofer HU. Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype. The Journal of Clinical Investigation. 115: 673-9. PMID 15719070 DOI: 10.1172/JCI23618  0.381
2005 Watanabe H, Katoh T, Eiro M, Iwamoto M, Ushikubi F, Narumiya S, Watanabe T. Effects of salt loading on blood pressure in mice lacking the prostanoid receptor gene. Circulation Journal : Official Journal of the Japanese Circulation Society. 69: 124-6. PMID 15635218 DOI: JST.JSTAGE/circj/69.124  0.34
2005 Kawamori T, Kitamura T, Watanabe K, Uchiya N, Maruyama T, Narumiya S, Sugimura T, Wakabayashi K. Prostaglandin E receptor subtype EP(1) deficiency inhibits colon cancer development. Carcinogenesis. 26: 353-7. PMID 15564292 DOI: 10.1093/carcin/bgh322  0.388
2004 Fujino T, Nakagawa N, Yuhki K, Hara A, Yamada T, Takayama K, Kuriyama S, Hosoki Y, Takahata O, Taniguchi T, Fukuzawa J, Hasebe N, Kikuchi K, Narumiya S, Ushikubi F. Decreased susceptibility to renovascular hypertension in mice lacking the prostaglandin I2 receptor IP. The Journal of Clinical Investigation. 114: 805-12. PMID 15372104 DOI: 10.1172/JCI21382  0.346
2004 Kobayashi T, Tahara Y, Matsumoto M, Iguchi M, Sano H, Murayama T, Arai H, Oida H, Yurugi-Kobayashi T, Yamashita JK, Katagiri H, Majima M, Yokode M, Kita T, Narumiya S. Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice. The Journal of Clinical Investigation. 114: 784-94. PMID 15372102 DOI: 10.1172/JCI21446  0.355
2004 Yuhki K, Ueno A, Naraba H, Kojima F, Ushikubi F, Narumiya S, Oh-ishi S. Prostaglandin receptors EP2, EP3, and IP mediate exudate formation in carrageenin-induced mouse pleurisy. The Journal of Pharmacology and Experimental Therapeutics. 311: 1218-24. PMID 15316088 DOI: 10.1124/jpet.104.071548  0.425
2004 Shoji Y, Takahashi M, Kitamura T, Watanabe K, Kawamori T, Maruyama T, Sugimoto Y, Negishi M, Narumiya S, Sugimura T, Wakabayashi K. Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development. Gut. 53: 1151-8. PMID 15247185 DOI: 10.1136/gut.2003.028787  0.356
2004 Ueda H, Morishita R, Narumiya S, Kato K, Asano T. Galphaq/11 signaling induces apoptosis through two pathways involving reduction of Akt phosphorylation and activation of RhoA in HeLa cells. Experimental Cell Research. 298: 207-17. PMID 15242775 DOI: 10.1016/j.yexcr.2004.04.015  0.337
2004 Xiao CY, Yuhki K, Hara A, Fujino T, Kuriyama S, Yamada T, Takayama K, Takahata O, Karibe H, Taniguchi T, Narumiya S, Ushikubi F. Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4. Circulation. 109: 2462-8. PMID 15123528 DOI: 10.1161/01.CIR.0000128046.54681.97  0.314
2004 Schweda F, Klar J, Narumiya S, Nüsing RM, Kurtz A. Stimulation of renin release by prostaglandin E2 is mediated by EP2 and EP4 receptors in mouse kidneys. American Journal of Physiology. Renal Physiology. 287: F427-33. PMID 15113745 DOI: 10.1152/ajprenal.00072.2004  0.377
2004 Katagiri H, Ito Y, Ishii K, Hayashi I, Suematsu M, Yamashina S, Murata T, Narumiya S, Kakita A, Majima M. Role of thromboxane derived from COX-1 and -2 in hepatic microcirculatory dysfunction during endotoxemia in mice. Hepatology (Baltimore, Md.). 39: 139-50. PMID 14752832 DOI: 10.1002/hep.20000  0.319
2004 Giagulli C, Scarpini E, Ottoboni L, Narumiya S, Butcher EC, Constantin G, Laudanna C. RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing. Immunity. 20: 25-35. PMID 14738762 DOI: 10.1016/S1074-7613(03)00350-9  0.305
2004 Kabashima K, Narumiya S, Miyachi Y. Prostanoid in muco-cutaneous immune response Inflammation and Regeneration. 24: 35-42. DOI: 10.2492/Jsir.24.35  0.412
2004 Eguchi N, Qu WM, Huang ZL, Sakata M, Narumiya S, Chen JF, Urade Y, Hayaishi O. Molecular mechanism of prostaglandin D2-mediated non-REM sleep homeostasis studied by gene-knockout mice Sleep and Biological Rhythms. 2: S17-S18. DOI: 10.1111/j.1479-8425.2004.00092.x  0.464
2003 Narumiya S. Prostanoids in immunity: roles revealed by mice deficient in their receptors. Life Sciences. 74: 391-5. PMID 14607267 DOI: 10.1016/J.Lfs.2003.09.025  0.436
2003 Hara A, Yuhki K, Fujino T, Narumiya S, Ushikubi F. [Pathophysiological roles of the prostanoids in the cardiovascular system: studies using mice deficient in prostanoid receptors]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 122: 384-90. PMID 14569157 DOI: 10.1254/Fpj.122.384  0.379
2003 Yamada T, Fujino T, Yuhki K, Hara A, Karibe H, Takahata O, Okada Y, Xiao CY, Takayama K, Kuriyama S, Taniguchi T, Shiokoshi T, Ohsaki Y, Kikuchi K, Narumiya S, et al. Thromboxane A2 regulates vascular tone via its inhibitory effect on the expression of inducible nitric oxide synthase. Circulation. 108: 2381-6. PMID 14557367 DOI: 10.1161/01.CIR.0000093194.21109.EC  0.348
2003 Hervé M, Angeli V, Pinzar E, Wintjens R, Faveeuw C, Narumiya S, Capron A, Urade Y, Capron M, Riveau G, Trottein F. Pivotal roles of the parasite PGD2 synthase and of the host D prostanoid receptor 1 in schistosome immune evasion. European Journal of Immunology. 33: 2764-72. PMID 14515260 DOI: 10.1002/Eji.200324143  0.343
2003 Kabashima K, Narumiya S. The DP receptor, allergic inflammation and asthma. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 69: 187-94. PMID 12895602 DOI: 10.1016/S0952-3278(03)00080-2  0.374
2003 Oka T, Oka K, Kobayashi T, Sugimoto Y, Ichikawa A, Ushikubi F, Narumiya S, Saper CB. Characteristics of thermoregulatory and febrile responses in mice deficient in prostaglandin EP1 and EP3 receptors. The Journal of Physiology. 551: 945-54. PMID 12837930 DOI: 10.1113/jphysiol.2003.048140  0.392
2003 Thumkeo D, Keel J, Ishizaki T, Hirose M, Nonomura K, Oshima H, Oshima M, Taketo MM, Narumiya S. Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death. Molecular and Cellular Biology. 23: 5043-55. PMID 12832488 DOI: 10.1128/Mcb.23.14.5043-5055.2003  0.34
2003 Minami T, Matsumura S, Mabuchi T, Kobayashi T, Sugimoto Y, Ushikubi F, Ichikawa A, Narumiya S, Ito S. Functional evidence for interaction between prostaglandin EP3 and kappa-opioid receptor pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1) glycoprotein gp120. Neuropharmacology. 45: 96-105. PMID 12814662 DOI: 10.1016/S0028-3908(03)00133-3  0.314
2003 Kabashima K, Murata T, Tanaka H, Matsuoka T, Sakata D, Yoshida N, Katagiri K, Kinashi T, Tanaka T, Miyasaka M, Nagai H, Ushikubi F, Narumiya S. Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity. Nature Immunology. 4: 694-701. PMID 12778172 DOI: 10.1038/ni943  0.327
2003 Kabashima K, Sakata D, Nagamachi M, Miyachi Y, Inaba K, Narumiya S. Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells. Nature Medicine. 9: 744-9. PMID 12740571 DOI: 10.1038/nm872  0.367
2003 Arakawa Y, Bito H, Furuyashiki T, Tsuji T, Takemoto-Kimura S, Kimura K, Nozaki K, Hashimoto N, Narumiya S. Control of axon elongation via an SDF-1alpha/Rho/mDia pathway in cultured cerebellar granule neurons. The Journal of Cell Biology. 161: 381-91. PMID 12707308 DOI: 10.1083/Jcb.200210149  0.553
2003 Nagao K, Tanaka H, Komai M, Masuda T, Narumiya S, Nagai H. Role of prostaglandin I2 in airway remodeling induced by repeated allergen challenge in mice. American Journal of Respiratory Cell and Molecular Biology. 29: 314-20. PMID 12676807 DOI: 10.1165/rcmb.2003-0035OC  0.334
2003 Faveeuw C, Gosset P, Bureau F, Angeli V, Hirai H, Maruyama T, Narumiya S, Capron M, Trottein F. Prostaglandin D2 inhibits the production of interleukin-12 in murine dendritic cells through multiple signaling pathways. European Journal of Immunology. 33: 889-98. PMID 12672054 DOI: 10.1002/Eji.200323330  0.337
2003 Matsuoka Y, Furuyashiki T, Bito H, Ushikubi F, Tanaka Y, Kobayashi T, Muro S, Satoh N, Kayahara T, Higashi M, Mizoguchi A, Shichi H, Fukuda Y, Nakao K, Narumiya S. Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes. Proceedings of the National Academy of Sciences of the United States of America. 100: 4132-7. PMID 12642666 DOI: 10.1073/Pnas.0633341100  0.616
2003 Takemoto-Kimura S, Terai H, Takamoto M, Ohmae S, Kikumura S, Segi E, Arakawa Y, Furuyashiki T, Narumiya S, Bito H. Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK). The Journal of Biological Chemistry. 278: 18597-605. PMID 12637513 DOI: 10.1074/Jbc.M300578200  0.518
2003 Saito O, Guan Y, Qi Z, Davis LS, Kömhoff M, Sugimoto Y, Narumiya S, Breyer RM, Breyer MD. Expression of the prostaglandin F receptor (FP) gene along the mouse genitourinary tract. American Journal of Physiology. Renal Physiology. 284: F1164-70. PMID 12631554 DOI: 10.1152/ajprenal.00441.2002  0.369
2003 Amano H, Hayashi I, Endo H, Kitasato H, Yamashina S, Maruyama T, Kobayashi M, Satoh K, Narita M, Sugimoto Y, Murata T, Yoshimura H, Narumiya S, Majima M. Host prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth. The Journal of Experimental Medicine. 197: 221-32. PMID 12538661 DOI: 10.1084/Jem.20021408  0.315
2003 Zhuge X, Arai H, Xu Y, Kita T, Kobayashi T, Narumiya S, Yokode M. 1P-0265 Role of monocyte-macrophage in atherosclerosis in thromboxane A2 receptor-deficient mice Atherosclerosis Supplements. 4: 77-78. DOI: 10.1016/S1567-5688(03)90336-9  0.347
2002 Kobayashi T, Narumiya S. Prostanoids in health and disease; lessons from receptor-knockout mice. Advances in Experimental Medicine and Biology. 507: 593-7. PMID 12664645 DOI: 10.1007/978-1-4615-0193-0_90  0.37
2002 Kobayashi T, Narumiya S. Function of prostanoid receptors: studies on knockout mice. Prostaglandins & Other Lipid Mediators. 68: 557-73. PMID 12432943 DOI: 10.1016/S0090-6980(02)00055-2  0.411
2002 Furuyashiki T, Arakawa Y, Takemoto-Kimura S, Bito H, Narumiya S. Multiple spatiotemporal modes of actin reorganization by NMDA receptors and voltage-gated Ca2+ channels. Proceedings of the National Academy of Sciences of the United States of America. 99: 14458-63. PMID 12391325 DOI: 10.1073/Pnas.212148999  0.584
2002 Takahashi Y, Tokuoka S, Masuda T, Hirano Y, Nagao M, Tanaka H, Inagaki N, Narumiya S, Nagai H. Augmentation of allergic inflammation in prostanoid IP receptor deficient mice. British Journal of Pharmacology. 137: 315-22. PMID 12237250 DOI: 10.1038/sj.bjp.0704872  0.391
2002 Göggel R, Hoffman S, Nüsing R, Narumiya S, Uhlig S. Platelet-activating factor-induced pulmonary edema is partly mediated by prostaglandin E(2), E-prostanoid 3-receptors, and potassium channels. American Journal of Respiratory and Critical Care Medicine. 166: 657-62. PMID 12204861 DOI: 10.1164/rccm.200111-071OC  0.333
2002 Fujino T, Yuhki K, Yamada T, Hara A, Takahata O, Okada Y, Xiao CY, Ma H, Karibe H, Iwashima Y, Fukuzawa J, Hasebe N, Kikuchi K, Narumiya S, Ushikubi F. Effects of the prostanoids on the proliferation or hypertrophy of cultured murine aortic smooth muscle cells. British Journal of Pharmacology. 136: 530-9. PMID 12055131 DOI: 10.1038/sj.bjp.0704749  0.374
2002 Tsuji T, Ishizaki T, Okamoto M, Higashida C, Kimura K, Furuyashiki T, Arakawa Y, Birge RB, Nakamoto T, Hirai H, Narumiya S. ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts. The Journal of Cell Biology. 157: 819-30. PMID 12021256 DOI: 10.1083/Jcb.200112107  0.597
2002 Ushikubi F, Narumiya S. [The roles of the prostanoids played in the body]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 119: 201-7. PMID 11979724 DOI: 10.1254/Fpj.119.201  0.395
2002 Kabashima K, Saji T, Murata T, Nagamachi M, Matsuoka T, Segi E, Tsuboi K, Sugimoto Y, Kobayashi T, Miyachi Y, Ichikawa A, Narumiya S. The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut. The Journal of Clinical Investigation. 109: 883-93. PMID 11927615 DOI: 10.1172/JCI14459  0.399
2002 Kabashima K, Narumiya S. Role of prostaglandin E2 in mucosal integrity and immune response. Ensho Saisei. 22: 535-541. DOI: 10.2492/Jsir.22.535  0.402
2002 Sugimoto Y, Tsuboi K, Narumiya S, Ichikawa A. Reproductive function of prostanoids: Lessons from receptor-deficient mice Nippon Nogeikagaku Kaishi-Journal of the Japan Society For Bioscience Biotechnology and Agrochemistry. 76: 1082-1085. DOI: 10.1271/Nogeikagaku1924.76.1082  0.367
2002 Eiro M, Katoh T, Ushikubi F, Narumiya S, Watanabe T. Lack of prostanoid receptor involvement in ischemic acute renal failure in mice Clinical and Experimental Nephrology. 6: 85-90. DOI: 10.1007/S101570200014  0.369
2001 Xiao CY, Hara A, Yuhki K, Fujino T, Ma H, Okada Y, Takahata O, Yamada T, Murata T, Narumiya S, Ushikubi F. Roles of prostaglandin I(2) and thromboxane A(2) in cardiac ischemia-reperfusion injury: a study using mice lacking their respective receptors. Circulation. 104: 2210-5. PMID 11684633 DOI: 10.1161/Hc4301.098058  0.326
2001 Mizoguchi A, Eguchi N, Kimura K, Kiyohara Y, Qu WM, Huang ZL, Mochizuki T, Lazarus M, Kobayashi T, Kaneko T, Narumiya S, Urade Y, Hayaishi O. Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep. Proceedings of the National Academy of Sciences of the United States of America. 98: 11674-9. PMID 11562489 DOI: 10.1073/Pnas.201398898  0.503
2001 Ueda H, Morishita R, Itoh H, Narumiya S, Mikoshiba K, Kato K, Asano T. Galpha11 induces caspase-mediated proteolytic activation of Rho-associated kinase, ROCK-I, in HeLa cells. The Journal of Biological Chemistry. 276: 42527-33. PMID 11546796 DOI: 10.1074/jbc.M102529200  0.331
2001 Ma H, Hara A, Xiao CY, Okada Y, Takahata O, Nakaya K, Sugimoto Y, Ichikawa A, Narumiya S, Ushikubi F. Increased bleeding tendency and decreased susceptibility to thromboembolism in mice lacking the prostaglandin E receptor subtype EP(3). Circulation. 104: 1176-80. PMID 11535576 DOI: 10.1161/Hc3601.094003  0.383
2001 Sonoshita M, Takaku K, Sasaki N, Sugimoto Y, Ushikubi F, Narumiya S, Oshima M, Taketo MM. Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice. Nature Medicine. 7: 1048-51. PMID 11533709 DOI: 10.1038/nm0901-1048  0.398
2001 Rodríguez-Fernández JL, Sánchez-Martín L, Rey M, Vicente-Manzanares M, Narumiya S, Teixidó J, Sánchez-Madrid F, Cabañas C. Rho and Rho-associated kinase modulate the tyrosine kinase PYK2 in T-cells through regulation of the activity of the integrin LFA-1. The Journal of Biological Chemistry. 276: 40518-27. PMID 11489881 DOI: 10.1074/jbc.M102896200  0.325
2001 Narumiya S, FitzGerald GA. Genetic and pharmacological analysis of prostanoid receptor function. The Journal of Clinical Investigation. 108: 25-30. PMID 11435452 DOI: 10.1172/JCI13455  0.36
2001 Ueno A, Matsumoto H, Naraba H, Ikeda Y, Ushikubi F, Matsuoka T, Narumiya S, Sugimoto Y, Ichikawa A, Oh-ishi S. Major roles of prostanoid receptors IP and EP(3) in endotoxin-induced enhancement of pain perception. Biochemical Pharmacology. 62: 157-60. PMID 11389873 DOI: 10.1016/S0006-2952(01)00654-2  0.413
2001 Minami T, Nakano H, Kobayashi T, Sugimoto Y, Ushikubi F, Ichikawa A, Narumiya S, Ito S. Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice. British Journal of Pharmacology. 133: 438-44. PMID 11375261 DOI: 10.1038/sj.bjp.0704092  0.414
2001 Shinomiya S, Naraba H, Ueno A, Utsunomiya I, Maruyama T, Ohuchida S, Ushikubi F, Yuki K, Narumiya S, Sugimoto Y, Ichikawa A, Oh-ishi S. Regulation of TNFalpha and interleukin-10 production by prostaglandins I(2) and E(2): studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists. Biochemical Pharmacology. 61: 1153-60. PMID 11301049 DOI: 10.1016/S0006-2952(01)00586-X  0.392
2001 Chen M, Kakutani M, Naruko T, Ueda M, Narumiya S, Masaki T, Sawamura T. Activation-dependent surface expression of LOX-1 in human platelets. Biochemical and Biophysical Research Communications. 282: 153-8. PMID 11263985 DOI: 10.1006/bbrc.2001.4516  0.308
2001 Amano T, Tanabe K, Eto T, Narumiya S, Mizuno K. LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505. The Biochemical Journal. 354: 149-59. PMID 11171090 DOI: 10.1042/0264-6021:3540149  0.311
2001 Ishizaki T, Morishima Y, Okamoto M, Furuyashiki T, Kato T, Narumiya S. Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1. Nature Cell Biology. 3: 8-14. PMID 11146620 DOI: 10.1038/35050598  0.571
2000 Kotani M, Tanaka I, Ogawa Y, Suganami T, Matsumoto T, Muro S, Yamamoto Y, Sugawara A, Yoshimasa Y, Sagawa N, Narumiya S, Nakao K. Multiple signal transduction pathways through two prostaglandin E receptor EP3 subtype isoforms expressed in human uterus. The Journal of Clinical Endocrinology and Metabolism. 85: 4315-22. PMID 11095474 DOI: 10.1210/jcem.85.11.6989  0.322
2000 Sakuma Y, Tanaka K, Suda M, Komatsu Y, Yasoda A, Miura M, Ozasa A, Narumiya S, Sugimoto Y, Ichikawa A, Ushikubi F, Nakao K. Impaired bone resorption by lipopolysaccharide in vivo in mice deficient in the prostaglandin E receptor EP4 subtype. Infection and Immunity. 68: 6819-25. PMID 11083800 DOI: 10.1128/Iai.68.12.6819-6825.2000  0.345
2000 Muro S, Tanaka I, Usui T, Kotani M, Koide S, Mukoyama M, Fukata J, Itoh H, Narumiya S, Kawata M, Nakao K. Expression of prostaglandin E receptor EP4 subtype in rat adrenal zona glomerulosa: involvement in aldosterone release. Endocrine Journal. 47: 429-36. PMID 11075723 DOI: 10.1507/Endocrj.47.429  0.36
2000 Okada Y, Hara A, Ma H, Xiao CY, Takahata O, Kohgo Y, Narumiya S, Ushikubi F. Characterization of prostanoid receptors mediating contraction of the gastric fundus and ileum: studies using mice deficient in prostanoid receptors. British Journal of Pharmacology. 131: 745-55. PMID 11030724 DOI: 10.1038/sj.bjp.0703627  0.318
2000 Ushikubi F, Sugimoto Y, Ichikawa A, Narumiya S. Roles of prostanoids revealed from studies using mice lacking specific prostanoid receptors. Japanese Journal of Pharmacology. 83: 279-85. PMID 11001172 DOI: 10.1254/Jjp.83.279  0.414
2000 Sugimoto Y, Narumiya S, Ichikawa A. Distribution and function of prostanoid receptors: studies from knockout mice. Progress in Lipid Research. 39: 289-314. PMID 10856600 DOI: 10.1016/S0163-7827(00)00008-4  0.401
2000 Watanabe K, Kawamori T, Nakatsugi S, Ohta T, Ohuchida S, Yamamoto H, Maruyama T, Kondo K, Narumiya S, Sugimura T, Wakabayashi K. Inhibitory effect of a prostaglandin E receptor subtype EP(1) selective antagonist, ONO-8713, on development of azoxymethane-induced aberrant crypt foci in mice. Cancer Letters. 156: 57-61. PMID 10840160 DOI: 10.1016/S0304-3835(00)00440-7  0.395
2000 Bito H, Furuyashiki T, Ishihara H, Shibasaki Y, Ohashi K, Mizuno K, Maekawa M, Ishizaki T, Narumiya S. A critical role for a Rho-associated kinase, p160ROCK, in determining axon outgrowth in mammalian CNS neurons. Neuron. 26: 431-41. PMID 10839361 DOI: 10.1016/S0896-6273(00)81175-7  0.549
2000 Kobayashi T, Ushikubi F, Narumiya S. Amino acid residues conferring ligand binding properties of prostaglandin I and prostaglandin D receptors. Identification by site-directed mutagenesis. The Journal of Biological Chemistry. 275: 24294-303. PMID 10827082 DOI: 10.1074/jbc.M002437200  0.315
2000 Madaule P, Furuyashiki T, Eda M, Bito H, Ishizaki T, Narumiya S. Citron, a Rho target that affects contractility during cytokinesis. Microscopy Research and Technique. 49: 123-6. PMID 10816250 DOI: 10.1002/(Sici)1097-0029(20000415)49:2<123::Aid-Jemt3>3.0.Co;2-R  0.608
2000 Chen M, Kakutani M, Minami M, Kataoka H, Kume N, Narumiya S, Kita T, Masaki T, Sawamura T. Increased expression of lectin-like oxidized low density lipoprotein receptor-1 in initial atherosclerotic lesions of Watanabe heritable hyperlipidemic rabbits. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1107-15. PMID 10764681 DOI: 10.1161/01.Atv.20.4.1107  0.302
2000 Miyaura C, Inada M, Suzawa T, Sugimoto Y, Ushikubi F, Ichikawa A, Narumiya S, Suda T. Impaired bone resorption to prostaglandin E2 in prostaglandin E receptor EP4-knockout mice. The Journal of Biological Chemistry. 275: 19819-23. PMID 10749873 DOI: 10.1074/jbc.M002079200  0.335
2000 Suzawa T, Miyaura C, Inada M, Maruyama T, Sugimoto Y, Ushikubi F, Ichikawa A, Narumiya S, Suda T. The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs. Endocrinology. 141: 1554-9. PMID 10746663 DOI: 10.1210/endo.141.4.7405  0.336
2000 Ueno A, Naraba H, Ikeda Y, Ushikubi F, Murata T, Narumiya S, Oh-ishi S. Intrinsic prostacyclin contributes to exudation induced by bradykinin or carrageenin: a study on the paw edema induced in IP-receptor-deficient mice. Life Sciences. 66: PL155-60. PMID 10737367 DOI: 10.1016/S0024-3205(00)00420-3  0.39
2000 Matsuoka T, Hirata M, Tanaka H, Takahashi Y, Murata T, Kabashima K, Sugimoto Y, Kobayashi T, Ushikubi F, Aze Y, Eguchi N, Urade Y, Yoshida N, Kimura K, Mizoguchi A, ... ... Narumiya S, et al. Prostaglandin D2 as a mediator of allergic asthma. Science (New York, N.Y.). 287: 2013-7. PMID 10720327 DOI: 10.1126/SCIENCE.287.5460.2013  0.35
2000 Croy BA, Chantakru S, Narumiya S, Ichikawa A, Sugimoto Y. Prolonged gestation does not extend survival of uterine natural killer lymphocytes in mice deleted in the receptor for prostaglandin F2alpha. Journal of Reproductive Immunology. 46: 125-9. PMID 10706943 DOI: 10.1016/S0165-0378(99)00057-1  0.335
2000 Sakuma Y, Tanaka K, Suda M, Yasoda A, Natsui K, Tanaka I, Ushikubi F, Narumiya S, Segi E, Sugimoto Y, Ichikawa A, Nakao K. Crucial involvement of the EP4 subtype of prostaglandin E receptor in osteoclast formation by proinflammatory cytokines and lipopolysaccharide. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 15: 218-27. PMID 10703923 DOI: 10.1359/jbmr.2000.15.2.218  0.356
2000 Suda M, Tanaka K, Sakuma Y, Yasoda A, Ozasa A, Fukata J, Tanaka I, Narumiya S, Nakao K. Prostaglandin E(2) (PGE(2)) induces the c-fos and c-jun expressions via the EP(1) subtype of PGE receptor in mouse osteoblastic MC3T3-E1 cells. Calcified Tissue International. 66: 217-23. PMID 10666498 DOI: 10.1007/S002230010043  0.32
2000 Kobayashi T, Narumiya S. Studies of the prostanoid receptors for specific agonist/antagonist. Folia Pharmacologica Japonica. 116: 38-42. DOI: 10.1254/Fpj.116.Supplement_38  0.34
2000 Boku K, Saeki T, Ohno T, Kamata K, Saigenji K, Hayashi I, Katori M, Marata T, Narumiya S, Majima M. Lack of mild irritant-induced adaptive cytoprotection in IP receptor knockout mice. —The involvement of endogenous calcitonin gene-related peptide— Gastroenterology. 118: A232. DOI: 10.1016/S0016-5085(00)83004-8  0.377
1999 Ohishi S, Ueno A, Matsumoto H, Murata T, Ushikubi F, Narumiya S. Evidence for involvement of prostaglandin I2 as a major nociceptive mediator in acetic acid-induced writhing reaction: a study using IP-receptor disrupted mice. Advances in Experimental Medicine and Biology. 469: 265-8. PMID 10667340 DOI: 10.1007/978-1-4615-4793-8_39  0.313
1999 Kobayashi T, Ushikubi F, Narumiya S. [Determination of ligand binding domains of the prostanoid receptors]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 114: 127P-129P. PMID 10629869 DOI: 10.1254/Fpj.114.Supplement_127  0.346
1999 Narumiya S. [Cellular functions & pharmacological manipulations of the small GTPase Rho & Rho effectors]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 114: 1P-5P. PMID 10629846 DOI: 10.1254/Fpj.114.Supplement_1  0.326
1999 Watanabe N, Kato T, Fujita A, Ishizaki T, Narumiya S. Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nature Cell Biology. 1: 136-43. PMID 10559899 DOI: 10.1038/11056  0.315
1999 Takeuchi K, Ukawa H, Kato S, Furukawa O, Araki H, Sugimoto Y, Ichikawa A, Ushikubi F, Narumiya S. Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E–receptor subtype EP3 Gastroenterology. 117: 1128-1135. PMID 10535876 DOI: 10.1016/S0016-5085(99)70398-7  0.336
1999 Narumiya S, Sugimoto Y, Ushikubi F. Prostanoid Receptors: Structures, Properties, and Functions Physiological Reviews. 79: 1193-1226. PMID 10508233 DOI: 10.1152/Physrev.1999.79.4.1193  0.378
1999 Hizaki H, Segi E, Sugimoto Y, Hirose M, Saji T, Ushikubi F, Matsuoka T, Noda Y, Tanaka T, Yoshida N, Narumiya S, Ichikawa A. Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP2 Proceedings of the National Academy of Sciences of the United States of America. 96: 10501-10506. PMID 10468638 DOI: 10.1073/Pnas.96.18.10501  0.362
1999 Itoh K, Yoshioka K, Akedo H, Uehata M, Ishizaki T, Narumiya S. An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. Nature Medicine. 5: 221-225. PMID 9930872 DOI: 10.1038/5587  0.307
1999 Furuyashiki T, Fujisawa K, Fujita A, Madaule P, Uchino S, Mishina M, Bito H, Narumiya S. Citron, a Rho-target, interacts with PSD-95/SAP-90 at glutamatergic synapses in the thalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 109-18. PMID 9870943 DOI: 10.1523/Jneurosci.19-01-00109.1999  0.6
1999 Shiraishi Y, Mizutani A, Bito H, Fujisawa K, Narumiya S, Mikoshiba K, Furuichi T. Cupidin, an Isoform of Homer/Vesl, Interacts with the Actin Cytoskeleton and Activated Rho Family Small GTPases and Is Expressed in Developing Mouse Cerebellar Granule Cells The Journal of Neuroscience. 19: 8389-8400. DOI: 10.1523/Jneurosci.19-19-08389.1999  0.311
1999 Suzuki Y, Yamamoto M, Wada H, Ito M, Nakano T, Sasaki Y, Narumiya S, Shiku H, Nishikawa M. Agonist-induced regulation of myosin phosphatase activity in human platelets through activation of Rho-kinase Blood. 93: 3408-3417. DOI: 10.1182/Blood.V93.10.3408.410K37_3408_3417  0.302
1999 Matsuoka T, Hirata M, Murata T, Kobayashi T, Ushikubi F, Tanaka H, Nagal H, Narumiya S. Mice lacking the prostaglading d receptor are resistant to eosinophil recruitment and airway hypersensitivy in bronchial asthma induced by ovalubmin Prostaglandins & Other Lipid Mediators. 59: 222. DOI: 10.1016/S0090-6980(99)90457-4  0.327
1999 Watanabe K, Kawamori T, Maruyama T, Ushikubi F, Narumiya S, Sugimura T, Wakabayashi K. Role of prostanoid receptors in colon carcinogenesis Prostaglandins & Other Lipid Mediators. 59: 221. DOI: 10.1016/S0090-6980(99)90456-2  0.351
1999 Matsuoka Y, Bito H, Matsuoka T, Kobayashi T, Sugimoto Y, Segi E, Ichikawa A, Nishida N, Ushikubi F, Nakao K, Narumiya S. Role of prostaglandin e receptors in LPS-induced ACTH release Prostaglandins & Other Lipid Mediators. 59: 177. DOI: 10.1016/S0090-6980(99)90412-4  0.329
1999 Kabashima K, Murata T, Tanaka H, Matsuoka T, Matsuoka Y, Nagai H, Ushikubi F, Narumiya S. Enhanced immune responses in mice lacking the thromboxane A2 receptor Prostaglandins & Other Lipid Mediators. 59: 161. DOI: 10.1016/S0090-6980(99)90396-9  0.337
1999 Narumiya S. Physiology and pathophysiology of the prostanoid receptors; Lessons from knockout mice studies Prostaglandins & Other Lipid Mediators. 59: 84. DOI: 10.1016/S0090-6980(99)90319-2  0.388
1998 Sugimoto Y, Segi E, Tsuboi K, Ichikawa A, Narumiya S. Female reproduction in mice lacking the prostaglandin F receptor. Roles of prostaglandin and oxytocin receptors in parturition. Advances in Experimental Medicine and Biology. 449: 317-321. PMID 10026819 DOI: 10.1007/978-1-4615-4871-3_39  0.39
1998 Ushikubi F, Segi E, Sugimoto Y, Murata T, Matsuoka T, Kobayashi T, Hizaki H, Tuboi K, Katsuyama M, Ichikawa A, Tanaka T, Yoshida N, Narumiya S. Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3. Nature. 395: 281-284. PMID 9751056 DOI: 10.1038/26233  0.393
1998 Tominaga T, Ishizaki T, Narumiya S, Barber DL. p160ROCK mediates RhoA activation of Na-H exchange Embo Journal. 17: 4712-4722. PMID 9707430 DOI: 10.1093/Emboj/17.16.4712  0.324
1998 Tsuzuki S, Toyama-Sorimachi N, Kitamura F, Tsuboi H, Ando J, Sakurai T, Morii N, Narumiya S, Miyasaka M. Intracellular Signal-transducing elements involved in transendothelial migration of lymphoma cells. Japanese Journal of Cancer Research. 89: 571-577. PMID 9685862 DOI: 10.1111/J.1349-7006.1998.Tb03299.X  0.319
1998 Hirose M, Ishizaki T, Watanabe N, Uehata M, Kranenburg O, Moolenaar WH, Matsumura F, Maekawa M, Bito H, Narumiya S. Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells. The Journal of Cell Biology. 141: 1625-36. PMID 9647654 DOI: 10.1083/Jcb.141.7.1625  0.338
1998 Yamaguchi M, Nakamoto M, Honda H, Nakagawa T, Fujita H, Nakamura T, Hirai H, Narumiya S, Kakizuka A. Retardation of skeletal development and cervical abnormalities in transgenic mice expressing a dominant-negative retinoic acid receptor in chondrogenic cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 7491-6. PMID 9636177 DOI: 10.1073/Pnas.95.13.7491  0.339
1998 Buscà R, Bertolotto C, Abbe P, Englaro W, Ishizaki T, Narumiya S, Boquet P, Ortonne JP, Ballotti R. Inhibition of Rho Is Required for cAMP-induced Melanoma Cell Differentiation Molecular Biology of the Cell. 9: 1367-1378. PMID 9614180 DOI: 10.1091/Mbc.9.6.1367  0.353
1998 Altun-Gultekin ZF, Chandriani S, Bougeret C, Ishizaki T, Narumiya S, de Graaf P, Van Bergen en Henegouwen P, Hanafusa H, Wagner JA, Birge RB. Activation of Rho-dependent cell spreading and focal adhesion biogenesis by the v-Crk adaptor protein. Molecular and Cellular Biology. 18: 3044-58. PMID 9566923 DOI: 10.1128/Mcb.18.5.3044  0.324
1998 Wijk TvD, Dorrestijn J, Narumiya S, Maassen JA, Jonge HRD, Tilly BC. Osmotic swelling-induced activation of the extracellular-signal-regulated protein kinases Erk-1 and Erk-2 in Intestine 407 cells involves the Ras/Raf-signalling pathway Biochemical Journal. 331: 863-869. PMID 9560315 DOI: 10.1042/Bj3310863  0.314
1998 Suda M, Tanaka K, Yasoda A, Natsui K, Sakuma Y, Tanaka I, Ushikubi F, Narumiya S, Nakao K. Prostaglandin E2 (PGE2) Autoamplifies its Production Through EP1 Subtype of PGE Receptor in Mouse Osteoblastic MC3T3-E1 Cells Calcified Tissue International. 62: 327-331. PMID 9504958 DOI: 10.1007/S002239900440  0.382
1998 Furuyashiki T, Fujisawa K, Fujita A, Madaule P, Kikumura S, Uchino S, Mishina M, Bito H, Narumiya S. Citron, a Rho-target, interacts with PSD-95 at glutamatergic synapses in the thalamus Neuroscience Research. 31. DOI: 10.1016/S0168-0102(98)82000-2  0.524
1997 Narumiya S, Ishizaki T, Watanabe N. Rho effectors and reorganization of actin cytoskeleton. Febs Letters. 410: 68-72. PMID 9247125 DOI: 10.1016/S0014-5793(97)00317-7  0.304
1997 Watanabe N, Madaule P, Reid T, Ishizaki T, Watanabe G, Kakizuka A, Saito Y, Nakao K, Jockusch BM, Narumiya S. p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. The Embo Journal. 16: 3044-3056. PMID 9214622 DOI: 10.1093/Emboj/16.11.3044  0.305
1997 Ding M, Kinoshita Y, Kishi K, Nakata H, Hassan S, Kawanami C, Sugimoto Y, Katsuyama M, Negishi M, Narumiya S, Ichikawa A, Chiba T. Distribution of prostaglandin E receptors in the rat gastrointestinal tract Prostaglandins. 53: 199-216. PMID 9206801 DOI: 10.1016/S0090-6980(97)00015-4  0.346
1997 Morimoto K, Sugimoto Y, Katsuyama M, Oida H, Tsuboi K, Kishi K, Kinoshita Y, Negishi M, Chiba T, Narumiya S, Ichikawa A. Cellular localization of mRNAs for prostaglandin E receptor subtypes in mouse gastrointestinal tract American Journal of Physiology-Gastrointestinal and Liver Physiology. 272. PMID 9124591 DOI: 10.1152/Ajpgi.1997.272.3.G681  0.338
1997 Ishizaki T, Naito M, Fujisawa K, Maekawa M, Watanabe N, Saito Y, Narumiya S. p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions Febs Letters. 404: 118-124. PMID 9119047 DOI: 10.1016/S0014-5793(97)00107-5  0.322
1997 Watanabe Y, Matsumura K, Murata T, Narumiya S, Kato K, Suzuki M, Noyori R, Watanabe Y. 215 Clearly different expression between CNS- and peripheral-type of prostacyclin receptor in the gene knockout mice for peripheral-type receptor and furth Neuroscience Research. 28. DOI: 10.1016/S0168-0102(97)90083-3  0.367
1996 Momiyama T, Todo N, Sugimoto Y, Ichikawa A, Narumiya S. Membrane depolarization by activation of prostaglandin E receptor EP3 subtype of putative serotonergic neurons in the dorsal raphe nucleus of the rat. Naunyn-Schmiedebergs Archives of Pharmacology. 353: 377-381. PMID 8935703 DOI: 10.1007/Bf00261433  0.36
1996 Kishi K, Hayashi H, Wang L, Kamohara S, Tamaoka K, Shimizu T, Ushikubi F, Narumiya S, Ebina Y. Gq-coupled Receptors Transmit the Signal for GLUT4 Translocation via an Insulin-independent Pathway Journal of Biological Chemistry. 271: 26561-26568. PMID 8900127 DOI: 10.1074/Jbc.271.43.26561  0.344
1996 Narumiya S. The small GTPase Rho: Cellular functions and signal transduction Journal of Biochemistry. 120: 215-228. PMID 8889802 DOI: 10.1093/Oxfordjournals.Jbchem.A021401  0.346
1996 Mori K, Tanaka I, Kotani M, Miyaoka F, Sando T, Muro S, Sasaki Y, Nakagawa O, Ogawa Y, Usui T, Ozaki S, Ichikawa A, Narumiya S, Nakao K. Gene expression of the human prostaglandin E receptor EP4 subtype: differential regulation in monocytoid and lymphoid lineage cells by phorbol ester. Journal of Molecular Medicine. 74: 333-336. PMID 8862514 DOI: 10.1007/Bf00207510  0.336
1996 Ishikawa TO, Tamai Y, Rochelle JM, Hirata M, Namba T, Sugimoto Y, Ichikawa A, Narumiya S, Taketo MM, Seldin MF. Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors Genomics. 32: 285-288. PMID 8833158 DOI: 10.1006/geno.1996.0118  0.331
1996 Reid T, Furuyashiki T, Ishizaki T, Watanabe G, Watanabe N, Fujisawa K, Morii N, Madaule P, Narumiya S. Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain. The Journal of Biological Chemistry. 271: 13556-60. PMID 8662891 DOI: 10.1074/Jbc.271.23.13556  0.565
1996 Hirata T, Ushikubi F, Kakizuka A, Okuma M, Narumiya S. Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation. Journal of Clinical Investigation. 97: 949-956. PMID 8613548 DOI: 10.1172/Jci118518  0.328
1996 Suda M, Tanaka K, Natsui K, Usui T, Tanaka I, Fukushima M, Shigeno C, Konishi J, Narumiya S, Ichikawa A, Nakao N. Prostaglandin E receptor subtypes in mouse osteoblastic cell line Endocrinology. 137: 1698-1705. PMID 8612504 DOI: 10.1210/Endo.137.5.8612504  0.356
1995 Nakagawa O, Sasaki Y, Tanaka I, Usui T, Sando T, Muro S, Mori K, Itoh H, Yoshimasa T, Narumiya S, Nakao K. Gene Expression Of Prostacyclin Receptor In The Hypertrophied Heart Of Spontaneously Hypertensive Rats Clinical and Experimental Pharmacology and Physiology. 22. PMID 9072386 DOI: 10.1111/J.1440-1681.1995.Tb02912.X  0.316
1995 Hirata M, Ushikubi F, Narumiya S. Prostaglandin I receptor and prostaglandin D receptor Journal of Lipid Mediators and Cell Signalling. 12: 393-404. PMID 8777581 DOI: 10.1016/0929-7855(95)00025-L  0.352
1995 Madaule P, Furuyashiki T, Reid T, Ishizaki T, Watanabe G, Morii N, Narumiya S. A novel partner for the GTP-bound forms of rho and rac. Febs Letters. 377: 243-8. PMID 8543060 DOI: 10.1016/0014-5793(95)01351-2  0.549
1995 Nishigaki N, Negishi M, Honda A, Sugimoto Y, Namba T, Narumiya S, Ichikawa A. Identification of prostaglandin E receptor ‘EP2’ cloned from mastocytoma cells as EP4 subtype Febs Letters. 364: 339-341. PMID 7758593 DOI: 10.1016/0014-5793(95)00421-5  0.383
1995 Katsuyama M, Nishigaki N, Sugimoto Y, Morimoto K, Negishi M, Narumiya S, Ichikawa A. The mouse prostaglandin E receptor EP2 subtype: cloning, expression, and Northern blot analysis Febs Letters. 372: 151-156. PMID 7556658 DOI: 10.1016/0014-5793(95)00966-D  0.387
1995 Naribayashi-Inomoto Y, Ding M, Nakata H, Narumiya S, Sugimoto Y, Honda A, Ichikawa A, Chiba T, Kinoshita Y. Copresence of prostaglandin EP2 and EP3 receptors on gastric enterochromaffin-like cell carcinoid in African rodents Gastroenterology. 109: 341-347. PMID 7542217 DOI: 10.1016/0016-5085(95)90319-4  0.361
1995 Saitou M, Sugai S, Tanaka T, Shimouchi K, Fuchs E, Narumiya S, Kakizuka A. Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor. Nature. 374: 159-62. PMID 7533262 DOI: 10.1038/374159A0  0.312
1995 Tominaga T, Narumiya S. Lymphocyte aggregation assay and inhibition by Clostridium botulinum C3 ADP-ribosyltransferase Methods in Enzymology. 256: 290-297. PMID 7476443 DOI: 10.1016/0076-6879(95)56033-5  0.315
1994 Sugimoto Y, Namba T, Shigemoto R, Negishi M, Ichikawa A, Narumiya S. Distinct cellular localization of mRNAs for three subtypes of prostaglandin E receptor in kidney. The American Journal of Physiology. 266: F823-8. PMID 8203567 DOI: 10.1152/Ajprenal.1994.266.5.F823  0.325
1994 Sando T, Usui T, Tanaka I, Mori K, Sasaki Y, Fukuda Y, Namba T, Sugimoto Y, Ichikawa A, Narumiya S, Nakao K. Molecular cloning and expression of rat prostaglandin E receptor EP2 subtype. Biochemical and Biophysical Research Communications. 200: 1329-1333. PMID 8185583 DOI: 10.1006/Bbrc.1994.1596  0.328
1994 Hirata T, Kakizuka A, Ushikubi F, Fuse I, Okuma M, Narumiya S. Arg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorder. Journal of Clinical Investigation. 94: 1662-1667. PMID 7929844 DOI: 10.1172/Jci117510  0.332
1994 Nakagawa O, Tanaka I, Usui T, Harada M, Sasaki Y, Itoh H, Yoshimasa T, Namba T, Narumiya S, Nakao K. Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system. Circulation. 90: 1643-1647. PMID 7923647 DOI: 10.1161/01.Cir.90.4.1643  0.363
1994 Sasaki Y, Usui T, Tanaka I, Nakagawa O, Sando T, Takahashi T, Namba T, Narumiya S, Nakao K. Cloning and expression of a cDNA for rat prostacyclin receptor. Biochimica Et Biophysica Acta. 1224: 601-605. PMID 7803522 DOI: 10.1016/0167-4889(94)90300-X  0.326
1994 Rankin S, Morii N, Narumiya S, Rozengurt E. Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin. Febs Letters. 354: 315-9. PMID 7525357 DOI: 10.1016/0014-5793(94)01148-6  0.313
1994 Katsuyama M, Sugimoto Y, Namba T, Irie A, Negishi M, Narumiya S, Ichikawa A. Cloning and expression of a cDNA for the human prostacyclin receptor Febs Letters. 344: 74-78. PMID 7514139 DOI: 10.1016/0014-5793(94)00355-6  0.354
1993 Negishi M, Sugimoto Y, Hayashi Y, Namba T, Honda A, Watabe A, Narumiya S, Ichikawa A. Functional interaction of prostaglandin E receptor EP3 subtype with guanine nucleotide-binding proteins, showing low-affinity ligand binding Biochimica Et Biophysica Acta. 1175: 343-350. PMID 8382086 DOI: 10.1016/0167-4889(93)90227-G  0.338
1993 Irie A, Sugimoto Y, Namba T, Harazono A, Honda A, Watabe A, Negishi M, Narumiya S, Ichikawa A. Third isoform of the prostaglandin‐E‐receptor EP3 subtype with different C‐terminal tail coupling to both stimulation and inhibition of adenylate cyclase Febs Journal. 217: 313-318. PMID 8223569 DOI: 10.1111/J.1432-1033.1993.Tb18248.X  0.345
1993 Nishigaki N, Negishl M, Sugimoto Y, Namba T, Narumiya S, Ichikawa A. Characterization of the prostaglandin E receptor expressed on a cultured mast cell line, BNu-2c13 Biochemical Pharmacology. 46: 863-869. PMID 7690567 DOI: 10.1016/0006-2952(93)90495-I  0.359
1993 Momiyama T, Todo N, Sugimoto Y, Narumiya S. 336 Function of prostaglandin E receptor in putative serotonergic neurons in the dorsal raphe nucleus of the rat Neuroscience Research Supplements. 18. DOI: 10.1016/S0921-8696(05)80806-0  0.306
1992 Namba T, Sugimoto Y, Hirata M, Hayashi Y, Honda A, Watabe A, Negishi M, Ichikawa A, Narumiya S. Mouse thromboxane A2 receptor: cDNA cloning, expression and northern blot analysis. Biochemical and Biophysical Research Communications. 184: 1197-1203. PMID 1375456 DOI: 10.1016/S0006-291X(05)80009-9  0.307
1992 Ushikubi F, Ishibashi T, Narumiya S, Okuma M. Analysis of the defective signal transduction mechanism through the platelet thromboxane A2 receptor in a patient with polycythemia vera. Thrombosis and Haemostasis. 67: 144-146. DOI: 10.1055/S-0038-1648396  0.341
1991 Hirata M, Hayashi Y, Ushikubi F, Yokota Y, Kageyama R, Nakanishi S, Narumiya S. Cloning and expression of cDNA for a human thromboxane A2 receptor. Nature. 349: 617-20. PMID 1825698 DOI: 10.1038/349617a0  0.54
1989 Nakajima M, Yamamoto M, Ushikubi F, Okuma M, Fujiwara M, Narumiya S. Expression of thromboxane A2 receptor in cultured human erythroleukemia cells and its induction by 12-O-tetradecanoylphorbol-13-acetate. Biochemical and Biophysical Research Communications. 158: 958-965. PMID 2522003 DOI: 10.1016/0006-291X(89)92815-5  0.305
1989 Ito S, Narumiya S, Hayaishi O. Prostaglandin D2: a biochemical perspective. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 37: 219-34. PMID 2510183 DOI: 10.1016/0952-3278(89)90033-1  0.414
1988 Hirata Y, Hayashi H, Ito S, Kikawa Y, Ishibashi M, Sudo M, Miyazaki H, Fukushima M, Narumiya S, Hayaishi O. Occurrence of 9-deoxy-delta 9,delta 12-13,14-dihydroprostaglandin D2 in human urine. The Journal of Biological Chemistry. 263: 16619-25. PMID 3053696  0.354
1987 Ushikubi F, Okuma M, Kanaji K, Sugiyama T, Ogorochi T, Narumiya S, Uchino H. Hemorrhagic thrombocytopathy with platelet thromboxane A2 receptor abnormality: defective signal transduction with normal binding activity. Thrombosis and Haemostasis. 57: 158-164. DOI: 10.1055/S-0038-1651086  0.31
1985 Ikai K, Danno K, Horio T, Narumiya S. Effect of Ultraviolet Irradiation on Mast Cell-Deficient W/Wv Mice Journal of Investigative Dermatology. 85: 82-84. PMID 3859552 DOI: 10.1111/1523-1747.Ep12275365  0.321
1985 Watanabe Y, Tokumoto H, Yamashita A, Narumiya S, Mizuno N, Hayaishi O. Specific bindings of prostaglandin D2, E2 and F2 alpha in postmortem human brain. Brain Research. 342: 110-6. PMID 2994820 DOI: 10.1016/0006-8993(85)91358-7  0.452
1984 Kikawa Y, Narumiya S, Fukushima M, Wakatsuka H, Hayaishi O. 9-Deoxy-delta 9, delta 12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma. Proceedings of the National Academy of Sciences of the United States of America. 81: 1317-21. PMID 6584883 DOI: 10.1073/Pnas.81.5.1317  0.438
1984 Ogorochi T, Narumiya S, Mizuno N, Yamashita K, Miyazaki H, Hayaishi O. Regional distribution of prostaglandins D2, E2, and F2 alpha and related enzymes in postmortem human brain. Journal of Neurochemistry. 43: 71-82. PMID 6427411 DOI: 10.1111/J.1471-4159.1984.Tb06680.X  0.459
1983 Osama H, Narumiya S, Hayaishi O, Iinuma H, Takeuchi T, Umezawa H. Inhibition of brain prostaglandin D synthetase and prostaglandin D2 dehydrogenase by some saturated and unsaturated fatty acids. Biochimica Et Biophysica Acta. 752: 251-8. PMID 6407532  0.358
1982 Watanabe T, Shimizu T, Narumiya S, Hayaishi O. [Metabolism and action of prostaglandin D2 in blood platelets]. Rinsho Byori. the Japanese Journal of Clinical Pathology. 9-20. PMID 7131811  0.341
1982 Ueno R, Narumiya S, Ogorochi T, Nakayama T, Ishikawa Y, Hayaishi O. Role of prostaglandin D2 in the hypothermia of rats caused by bacterial lipopolysaccharide. Proceedings of the National Academy of Sciences of the United States of America. 79: 6093-7. PMID 6964402 DOI: 10.1073/Pnas.79.19.6093  0.452
1982 Fukushima M, Kato T, Ota K, Arai Y, Narumiya S, Hayaishi O. 9-deoxy-delta 9-prostaglandin D2, a prostaglandin D2 derivative with potent antineoplastic and weak smooth muscle-contracting activities. Biochemical and Biophysical Research Communications. 109: 626-33. PMID 6961920 DOI: 10.1016/0006-291X(82)91986-6  0.453
1982 Narumiya S, Ogorochi T, Nakao K, Hayaishi O. Prostaglandin D2 in rat brain, spinal cord and pituitary: basal level and regional distribution. Life Sciences. 31: 2093-103. PMID 6960222 DOI: 10.1016/0024-3205(82)90101-1  0.443
1982 Watanabe T, Shimizu T, Narumiya S, Hayaishi O. NADP-linked 15-hydroxyprostaglandin dehydrogenase for prostaglandin D in human blood platelets. Archives of Biochemistry and Biophysics. 216: 372-9. PMID 6954879 DOI: 10.1016/0003-9861(82)90223-5  0.446
1982 Fukushima M, Kato T, Ueda R, Ota K, Narumiya S, Hayaishi O. Prostaglandin D2, a potential antineoplastic agent. Biochemical and Biophysical Research Communications. 105: 956-64. PMID 6953969 DOI: 10.1016/0006-291X(82)91063-4  0.458
1982 Watanabe T, Narumiya S, Shimizu T, Hayaishi O. Characterization of the biosynthetic pathway of prostaglandin D2 in human platelet-rich plasma. The Journal of Biological Chemistry. 257: 14847-53. PMID 6816798  0.367
1979 Ushiro H, Takai K, Narumiya S, Ito S, Hayaishi O. Isolation and reconstitution of two electron transfer components of tryptophan side chain oxidase. The Journal of Biological Chemistry. 254: 11794-7. PMID 500674  0.319
1979 Narumiya S, Takai K, Tokuyama T, Noda Y, Ushiro H, Hayaishi O. A new metabolic pathway of tryptophan initiated by tryptophan side chain oxidase. The Journal of Biological Chemistry. 254: 7007-15. PMID 110802  0.316
1978 Ushiro H, Takai K, Noda Y, Narumiya S, Tokuyama T, Hayaishi O. Tryptophan side chain oxidase from Pseudomonas. Oxidation of skatole to indole-3-carboxaldehyde via indole-3-methanol. The Journal of Biological Chemistry. 253: 9002-8. PMID 721824  0.309
1978 Noda Y, Takai K, Tokuyama T, Narumiya S, Ushiro H, Hayaishi O. Tryptophan side chain oxidase from Pseudomonas. pH-dependent formation of alpha,beta-didehydro, beta-hydroxy, and beta-keto derivatives of N-acetyltryptophanamide. The Journal of Biological Chemistry. 253: 4819-22. PMID 27505  0.314
1977 Noda Y, Takai K, Tokuyama T, Narumiya S, Ushiro H, Hayaishi O. Enzymatic oxidation of acetyltryptophanamide- and tryptophan-containing peptides. Formation of dehydrotryptophan. The Journal of Biological Chemistry. 252: 4413-5. PMID 863932  0.309
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