Steven A. Kushner - Publications

Affiliations: 
Neurobiological Psychiatry Erasmus Medical Center Rotterdam, Rotterdam, Netherlands 

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Castricum J, Birkenhager TK, Kushner SA, Elgersma Y, Tulen JHM. Cortical Inhibition and Plasticity in Major Depressive Disorder. Frontiers in Psychiatry. 13: 777422. PMID 35153873 DOI: 10.3389/fpsyt.2022.777422  0.522
2021 Lesuis SL, Brosens N, Immerzeel N, van der Loo RJ, Mitrić M, Bielefeld P, Fitzsimons CP, Lucassen PJ, Kushner SA, van den Oever MC, Krugers HJ. Glucocorticoids Promote Fear Generalization by Increasing the Size of a Dentate Gyrus Engram Cell Population. Biological Psychiatry. 90: 494-504. PMID 34503674 DOI: 10.1016/j.biopsych.2021.04.010  0.447
2021 Homberg JR, Adan RAH, Alenina N, Asiminas A, Bader M, Beckers T, Begg DP, Blokland A, Burger ME, van Dijk G, Eisel ULM, Elgersma Y, Englitz B, Fernandez-Ruiz A, Fitzsimons CP, ... ... Kushner SA, et al. The continued need for animals to advance brain research. Neuron. 109: 2374-2379. PMID 34352213 DOI: 10.1016/j.neuron.2021.07.015  0.72
2021 Borrie SC, Plasschaert E, Callaerts-Vegh Z, Yoshimura A, D'Hooge R, Elgersma Y, Kushner SA, Legius E, Brems H. MEK inhibition ameliorates social behavior phenotypes in a Spred1 knockout mouse model for RASopathy disorders. Molecular Autism. 12: 53. PMID 34311771 DOI: 10.1186/s13229-021-00458-2  0.512
2021 Hinman JD, Ngo KJ, Kim D, Chen C, Abraham CR, Ghanbari M, Ikram MA, Kushner SA, Kawaguchi R, Coppola G, Goth K, Bellusci S, Hernandez I, Kosik KS, Fogel BL. miR-142-3p Regulates Cortical Oligodendrocyte Gene Co-expression Networks Associated with Tauopathy. Human Molecular Genetics. PMID 33555315 DOI: 10.1093/hmg/ddaa252  0.768
2020 Genzel L, Adan R, Berns A, van den Beucken JJJP, Blokland A, Boddeke EHWGM, Bogers WM, Bontrop R, Bulthuis R, Bousema T, Clevers H, Coenen TCJJ, van Dam AM, Deen PMT, van Dijk KW, ... ... Kushner SA, et al. How the COVID-19 pandemic highlights the necessity of animal research. Current Biology : Cb. 30: 4328. PMID 33142090 DOI: 10.1016/j.cub.2020.10.033  0.75
2020 Castricum J, Tulen JHM, Taal W, Ottenhoff MJ, Kushner SA, Elgersma Y. Motor cortical excitability and plasticity in patients with neurofibromatosis type 1. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 131: 2673-2681. PMID 32977190 DOI: 10.1016/J.Clinph.2020.08.016  0.529
2020 Genzel L, Adan R, Berns A, van den Beucken J, Blokland A, Boddeke EHWGM, Bogers WM, Bontrop R, Bulthuis R, Bousema T, Clevers H, Coenen TCJJ, Dam AV, Deen PMT, van Dijk KW, ... ... Kushner SA, et al. How the COVID-19 pandemic highlights the necessity of animal research. Current Biology : Cb. 30: R1014-R1018. PMID 32961149 DOI: 10.1016/J.Cub.2020.08.030  0.754
2020 Zampeta IF, Sonzogni M, Niggl E, Lendemeijer B, Smeenk H, de Vrij FMS, Kushner SA, Distel B, Elgersma Y. Conserved UBE3A subcellular distribution between human and mice is facilitated by non-homologous isoforms. Human Molecular Genetics. PMID 32879944 DOI: 10.1093/Hmg/Ddaa194  0.529
2020 Vinueza-Veloz MF, Martín-Román C, Robalino-Valdivieso MP, White T, Kushner SA, De Zeeuw CI. Genetic risk for Alzheimer disease in children: Evidence from early-life IQ and brain white-matter microstructure. Genes, Brain, and Behavior. PMID 32383552 DOI: 10.1111/Gbb.12656  0.414
2020 Zhang Y, Venkateswaran S, Higuera GA, Nath S, Shpak G, Matray J, Fratila-Apachitei LE, Zadpoor AA, Kushner SA, Bradley M, De Zeeuw CI. Synthetic Polymers Provide a Robust Substrate for Functional Neuron Culture. Advanced Healthcare Materials. e1901347. PMID 31943855 DOI: 10.1002/Adhm.201901347  0.757
2020 Krugers H, Lesuis S, Xiong H, Loo Rvd, Kushner S, Lucassen P, oever MVd. Glucocorticoids Promote Fear Generalization by Altering Memory Encoding Neuronal Ensembles Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.101  0.456
2019 Stedehouder J, Brizee D, Slotman JA, Pascual-Garcia M, Leyrer ML, Bouwen BL, Dirven CM, Gao Z, Berson DM, Houtsmuller AB, Kushner SA. Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex. Elife. 8. PMID 31742557 DOI: 10.7554/Elife.48615  0.747
2019 Heimer G, van Woerden GM, Barel O, Marek-Yagel D, Kol N, Munting BJ, Borghei M, Atawneh OM, Nissenkorn A, Rechavi G, Anikster Y, Elgersma Y, Kushner SA, Ben Zeev B. Netrin-G2 dysfunction causes a Rett-like phenotype with areflexia. Human Mutation. PMID 31692205 DOI: 10.1002/Humu.23945  0.551
2019 Ghanbari M, Munshi ST, Ma B, Lendemeijer B, Bansal S, Adams HH, Wang W, Goth K, Slump DE, van den Hout MCGN, van IJcken WFJ, Bellusci S, Pan Q, Erkeland SJ, de Vrij FMS, ... Kushner SA, et al. A functional variant in the miR-142 promoter modulating its expression and conferring risk of Alzheimer disease. Human Mutation. PMID 31322790 DOI: 10.1002/Humu.23872  0.616
2019 Avagliano Trezza R, Sonzogni M, Bossuyt SNV, Zampeta FI, Punt AM, van den Berg M, Rotaru DC, Koene LMC, Munshi ST, Stedehouder J, Kros JM, Williams M, Heussler H, de Vrij FMS, Mientjes EJ, ... ... Kushner SA, et al. Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome. Nature Neuroscience. PMID 31235931 DOI: 10.1038/S41593-019-0425-0  0.772
2019 Rao-Ruiz P, Couey JJ, Marcelo IM, Bouwkamp CG, Slump DE, Matos MR, van der Loo RJ, Martins GJ, van den Hout M, van IJcken WF, Costa RM, van den Oever MC, Kushner SA. Engram-specific transcriptome profiling of contextual memory consolidation. Nature Communications. 10: 2232. PMID 31110186 DOI: 10.1038/S41467-019-09960-X  0.768
2019 Stedehouder J, Brizee D, Slotman JA, Pascual-Garcia M, Leyrer ML, Bouwen BL, Dirven CM, Gao Z, Berson DM, Houtsmuller AB, Kushner SA. Author response: Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex Elife. DOI: 10.7554/Elife.48615.Sa2  0.744
2019 Castricum J, Tulen J, Ottenhoff M, Taal W, Kushner S, Elgersma Y. Cortical plasticity induced by intermittent Theta Burst Stimulation in NF1 patients and unaffected controls Brain Stimulation. 12: 409. DOI: 10.1016/J.Brs.2018.12.319  0.511
2018 Rao-Ruiz P, Yu J, Kushner SA, Josselyn SA. Neuronal competition: microcircuit mechanisms define the sparsity of the engram. Current Opinion in Neurobiology. 54: 163-170. PMID 30423499 DOI: 10.1016/j.conb.2018.10.013  0.779
2018 Onori MP, Koopal B, Everman DB, Worthington JD, Jones JR, Ploeg MA, Mientjes E, van Bon BW, Kleefstra T, Schulman H, Kushner SA, Küry S, Elgersma Y, van Woerden GM. The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function. Human Mutation. PMID 30184290 DOI: 10.1002/Humu.23647  0.527
2018 Amin N, de Vrij FMS, Baghdadi M, Brouwer RWW, van Rooij JGJ, Jovanova O, Uitterlinden AG, Hofman A, Janssen HLA, Murad SD, Kraaij R, Stedehouder J, van den Hout MCGN, Kros JM, van IJcken WFJ, ... ... Kushner SA, et al. Employed family-based genetic discovery combining linkage analysis and exome sequencing to identify RCL1 as a novel candidate gene for depression, with independent replication in a population-based cohort. Molecular Psychiatry. 23: 1093. PMID 29731510 DOI: 10.1038/Mp.2018.6  0.763
2018 Stedehouder J, Brizee D, Shpak G, Kushner SA. Activity-Dependent Myelination of Parvalbumin Interneurons Mediated by Axonal Morphological Plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 38: 3631-3642. PMID 29507147 DOI: 10.1523/Jneurosci.0074-18.2018  0.768
2018 García-León JA, Kumar M, Boon R, Chau D, One J, Wolfs E, Eggermont K, Berckmans P, Gunhanlar N, de Vrij F, Lendemeijer B, Pavie B, Corthout N, Kushner SA, Dávila JC, et al. SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells. Stem Cell Reports. PMID 29337119 DOI: 10.1016/J.Stemcr.2017.12.014  0.785
2018 de Vrij FM, Bouwkamp CG, Gunhanlar N, Shpak G, Lendemeijer B, Baghdadi M, Gopalakrishna S, Ghazvini M, Li TM, Quadri M, Olgiati S, Breedveld GJ, Coesmans M, Mientjes E, de Wit T, ... ... Kushner SA, et al. Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia. Molecular Psychiatry. PMID 29302076 DOI: 10.1038/S41380-017-0004-2  0.768
2017 Stedehouder J, Couey JJ, Brizee D, Hosseini B, Slotman JA, Dirven CMF, Shpak G, Houtsmuller AB, Kushner SA. Fast-spiking Parvalbumin Interneurons are Frequently Myelinated in the Cerebral Cortex of Mice and Humans. Cerebral Cortex (New York, N.Y. : 1991). 27: 5001-5013. PMID 28922832 DOI: 10.1093/Cercor/Bhx203  0.767
2017 Higuera GA, Iaffaldano G, Bedar M, Shpak G, Broersen R, Munshi ST, Dupont C, Gribnau J, de Vrij FMS, Kushner SA, De Zeeuw CI. An expandable embryonic stem cell-derived Purkinje neuron progenitor population that exhibits in vivo maturation in the adult mouse cerebellum. Scientific Reports. 7: 8863. PMID 28821816 DOI: 10.1038/S41598-017-09348-1  0.772
2017 van Esbroeck ACM, Janssen APA, Cognetta AB, Ogasawara D, Shpak G, van der Kroeg M, Kantae V, Baggelaar MP, de Vrij FMS, Deng H, Allarà M, Fezza F, Lin Z, van der Wel T, Soethoudt M, ... ... Kushner SA, et al. Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474. Science (New York, N.Y.). 356: 1084-1087. PMID 28596366 DOI: 10.1126/Science.Aaf7497  0.76
2017 Schreiber J, Grimbergen LA, Overwater I, Vaart TV, Stedehouder J, Schuhmacher AJ, Guerra C, Kushner SA, Jaarsma D, Elgersma Y. Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse models. Scientific Reports. 7: 1256. PMID 28455524 DOI: 10.1038/S41598-017-01218-0  0.781
2017 Gunhanlar N, Shpak G, van der Kroeg M, Gouty-Colomer LA, Munshi ST, Lendemeijer B, Ghazvini M, Dupont C, Hoogendijk WJG, Gribnau J, de Vrij FMS, Kushner SA. A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells. Molecular Psychiatry. PMID 28416807 DOI: 10.1038/Mp.2017.56  0.77
2017 Vanhauwaert R, Kuenen S, Masius R, Bademosi A, Manetsberger J, Schoovaerts N, Bounti L, Gontcharenko S, Swerts J, Vilain S, Picillo M, Barone P, Munshi ST, de Vrij FM, Kushner SA, et al. The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals. The Embo Journal. PMID 28331029 DOI: 10.15252/Embj.201695773  0.472
2017 Amin N, de Vrij FM, Baghdadi M, Brouwer RW, van Rooij JG, Jovanova O, Uitterlinden AG, Hofman A, Janssen HL, Darwish Murad S, Kraaij R, Stedehouder J, van den Hout MC, Kros JM, van IJcken WF, ... ... Kushner SA, et al. A rare missense variant in RCL1 segregates with depression in extended families. Molecular Psychiatry. PMID 28322274 DOI: 10.1038/Mp.2017.49  0.772
2017 Zhou X, Huang F, Xu L, Lin Z, de Vrij FM, Ayo-Martin AC, van der Kroeg M, Zhao M, Yin Y, Wang W, Cao W, Wang Y, Kushner SA, Peron JM, Alric L, et al. Hepatitis E virus infects neurons and brains. The Journal of Infectious Diseases. PMID 28199701 DOI: 10.1093/Infdis/Jix079  0.424
2017 Borrie S, Plasschaert E, Elgersma Y, Kushner S, Legius E, Brems H. Social deficits in mouse models of Neurofibromatosis type 1 and Legius syndrome Frontiers in Neuroscience. 11. DOI: 10.3389/Conf.Fnins.2017.94.00027  0.511
2016 Peter S, Ten Brinke MM, Stedehouder J, Reinelt CM, Wu B, Zhou H, Zhou K, Boele HJ, Kushner SA, Lee MG, Schmeisser MJ, Boeckers TM, Schonewille M, Hoebeek FE, De Zeeuw CI. Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice. Nature Communications. 7: 12627. PMID 27581745 DOI: 10.1038/Ncomms12627  0.764
2016 Gouty-Colomer LA, Hosseini B, Marcelo IM, Schreiber J, Slump DE, Yamaguchi S, Houweling AR, Jaarsma D, Elgersma Y, Kushner SA. Arc expression identifies the lateral amygdala fear memory trace. Molecular Psychiatry. PMID 27217149 DOI: 10.1038/Mp.2016.91  0.677
2016 Stedehouder J, Kushner SA. Myelination of parvalbumin interneurons: a parsimonious locus of pathophysiological convergence in schizophrenia Molecular Psychiatry. DOI: 10.1038/Mp.2016.147  0.783
2015 Omrani A, van der Vaart T, Mientjes E, van Woerden GM, Hojjati MR, Li KW, Gutmann DH, Levelt CN, Smit AB, Silva AJ, Kushner SA, Elgersma Y. HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1. Molecular Psychiatry. PMID 25917366 DOI: 10.1038/Mp.2015.48  0.642
2015 Silva-Santos S, van Woerden GM, Bruinsma CF, Mientjes E, Jolfaei MA, Distel B, Kushner SA, Elgersma Y. Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model. The Journal of Clinical Investigation. 125: 2069-76. PMID 25866966 DOI: 10.1172/Jci80554  0.539
2015 Gouty-Colomer LA, Hosseini B, Marcelo IM, Schreiber J, Slump DE, Yamaguchi S, Houweling AR, Jaarsma D, Elgersma Y, Kushner SA. Arc expression identifies the lateral amygdala fear memory trace. Molecular Psychiatry. PMID 25802982 DOI: 10.1038/Mp.2015.18  0.693
2014 de Esch CE, Ghazvini M, Loos F, Schelling-Kazaryan N, Widagdo W, Munshi ST, van der Wal E, Douben H, Gunhanlar N, Kushner SA, Pijnappel WW, de Vrij FM, Geijsen N, Gribnau J, Willemsen R. Epigenetic characterization of the FMR1 promoter in induced pluripotent stem cells from human fibroblasts carrying an unmethylated full mutation. Stem Cell Reports. 3: 548-55. PMID 25358783 DOI: 10.1016/J.Stemcr.2014.07.013  0.763
2014 Achterberg KG, Buitendijk GH, Kool MJ, Goorden SM, Post L, Slump DE, Silva AJ, van Woerden GM, Kushner SA, Elgersma Y. Temporal and region-specific requirements of αCaMKII in spatial and contextual learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11180-7. PMID 25143599 DOI: 10.1523/Jneurosci.0640-14.2014  0.616
2014 Yiu AP, Mercaldo V, Yan C, Richards B, Rashid AJ, Hsiang HL, Pressey J, Mahadevan V, Tran MM, Kushner SA, Woodin MA, Frankland PW, Josselyn SA. Neurons are recruited to a memory trace based on relative neuronal excitability immediately before training. Neuron. 83: 722-35. PMID 25102562 DOI: 10.1016/J.Neuron.2014.07.017  0.661
2013 Galliano E, Potters JW, Elgersma Y, Wisden W, Kushner SA, De Zeeuw CI, Hoebeek FE. Synaptic transmission and plasticity at inputs to murine cerebellar Purkinje cells are largely dispensable for standard nonmotor tasks. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12599-618. PMID 23904597 DOI: 10.1523/Jneurosci.1642-13.2013  0.624
2011 Akers KG, Kushner SA, Leslie AT, Clarke L, van der Kooy D, Lerch JP, Frankland PW. Fetal alcohol exposure leads to abnormal olfactory bulb development and impaired odor discrimination in adult mice. Molecular Brain. 4: 29. PMID 21736737 DOI: 10.1186/1756-6606-4-29  0.482
2009 van Woerden GM, Hoebeek FE, Gao Z, Nagaraja RY, Hoogenraad CC, Kushner SA, Hansel C, De Zeeuw CI, Elgersma Y. betaCaMKII controls the direction of plasticity at parallel fiber-Purkinje cell synapses. Nature Neuroscience. 12: 823-5. PMID 19503086 DOI: 10.1038/Nn.2329  0.616
2009 Han JH, Kushner SA, Yiu AP, Hsiang HL, Buch T, Waisman A, Bontempi B, Neve RL, Frankland PW, Josselyn SA. Selective erasure of a fear memory. Science (New York, N.Y.). 323: 1492-6. PMID 19286560 DOI: 10.1126/Science.1164139  0.661
2008 Krab LC, de Goede-Bolder A, Aarsen FK, Pluijm SM, Bouman MJ, van der Geest JN, Lequin M, Catsman CE, Arts WF, Kushner SA, Silva AJ, de Zeeuw CI, Moll HA, Elgersma Y. Effect of simvastatin on cognitive functioning in children with neurofibromatosis type 1: a randomized controlled trial. Jama. 300: 287-94. PMID 18632543 DOI: 10.1001/Jama.300.3.287  0.67
2007 Han JH, Kushner SA, Yiu AP, Cole CJ, Matynia A, Brown RA, Neve RL, Guzowski JF, Silva AJ, Josselyn SA. Neuronal competition and selection during memory formation. Science (New York, N.Y.). 316: 457-60. PMID 17446403 DOI: 10.1126/Science.1139438  0.756
2005 Li W, Cui Y, Kushner SA, Brown RA, Jentsch JD, Frankland PW, Cannon TD, Silva AJ. The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1. Current Biology : Cb. 15: 1961-7. PMID 16271875 DOI: 10.1016/J.Cub.2005.09.043  0.775
2005 Kushner SA, Elgersma Y, Murphy GG, Jaarsma D, van Woerden GM, Hojjati MR, Cui Y, LeBoutillier JC, Marrone DF, Choi ES, De Zeeuw CI, Petit TL, Pozzo-Miller L, Silva AJ. Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9721-34. PMID 16237176 DOI: 10.1523/Jneurosci.2836-05.2005  0.77
2003 Frankland PW, Ohno M, Takahashi E, Chen AR, Costa RM, Kushner SA, Silva AJ. Pharmacologically regulated induction of silent mutations (PRISM): combined pharmacological and genetic approaches for learning and memory. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 9: 104-9. PMID 12708614 DOI: 10.1177/1073858403252225  0.712
2002 Matynia A, Kushner SA, Silva AJ. Genetic approaches to molecular and cellular cognition: a focus on LTP and learning and memory. Annual Review of Genetics. 36: 687-720. PMID 12429705 DOI: 10.1146/Annurev.Genet.36.062802.091007  0.64
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