Erminio Costa - Publications

National Institute of Mental Health, Bethesda, MD, United States 

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Kadriu B, Guidotti A, Costa E, Davis JM, Auta J. Acute imidazenil treatment after the onset of DFP-induced seizure is more effective and longer lasting than midazolam at preventing seizure activity and brain neuropathology. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 136-45. PMID 21097996 DOI: 10.1093/toxsci/kfq356  0.96
2010 Tueting P, Davis JM, Veldic M, Pibiri F, Kadriu B, Guidotti A, Costa E. L-methionine decreases dendritic spine density in mouse frontal cortex. Neuroreport. 21: 543-8. PMID 20442623 DOI: 10.1097/WNR.0b013e3283373126  0.96
2010 Smith RC, Zhubi A, Maloku E, Sershen H, Lajtha A, Davis JM, Costa E, Guidotti A. Varenicline treatment decreases DNMT1 mRNA expression in lymphocytes of schizophrenic patients who are cigarette smokers. Schizophrenia Research. 119: 269-70. PMID 20335008 DOI: 10.1016/j.schres.2010.02.1064  0.96
2010 Auta J, Kadriu B, Giusti P, Costa E, Guidotti A. Anticonvulsant, anxiolytic, and non-sedating actions of imidazenil and other imidazo-benzodiazepine carboxamide derivatives. Pharmacology, Biochemistry, and Behavior. 95: 383-9. PMID 20227434 DOI: 10.1016/j.pbb.2010.02.016  0.96
2010 Maloku E, Covelo IR, Hanbauer I, Guidotti A, Kadriu B, Hu Q, Davis JM, Costa E. Lower number of cerebellar Purkinje neurons in psychosis is associated with reduced reelin expression. Proceedings of the National Academy of Sciences of the United States of America. 107: 4407-11. PMID 20150511 DOI: 10.1073/pnas.0914483107  0.96
2009 Dong E, Grayson DR, Guidotti A, Costa E. Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation. Epigenomics. 1: 201-11. PMID 22122643 DOI: 10.2217/epi.09.2  0.96
2009 Pinna G, Costa E, Guidotti A. SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake. Current Opinion in Pharmacology. 9: 24-30. PMID 19157982 DOI: 10.1016/j.coph.2008.12.006  0.96
2009 Kadriu B, Guidotti A, Costa E, Auta J. Imidazenil, a non-sedating anticonvulsant benzodiazepine, is more potent than diazepam in protecting against DFP-induced seizures and neuronal damage. Toxicology. 256: 164-74. PMID 19111886 DOI: 10.1016/j.tox.2008.11.021  0.96
2009 Guidotti A, Dong E, Kundakovic M, Satta R, Grayson DR, Costa E. Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling. Trends in Pharmacological Sciences. 30: 55-60. PMID 19110320 DOI: 10.1016/  0.96
2009 Costa E, Chen Y, Dong E, Grayson DR, Kundakovic M, Maloku E, Ruzicka W, Satta R, Veldic M, Zhubi A, Guidotti A. GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability. Expert Review of Neurotherapeutics. 9: 87-98. PMID 19102671 DOI: 10.1586/14737175.9.1.87  0.96
2008 Pibiri F, Kozikowski AP, Pinna G, Auta J, Kadriu B, Costa E, Guidotti A. The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 14169-74. PMID 18784370 DOI: 10.1073/pnas.0807172105  0.96
2008 Auta J, Impagnatiello F, Kadriu B, Guidotti A, Costa E. Imidazenil: a low efficacy agonist at alpha1- but high efficacy at alpha5-GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem. Neuropharmacology. 55: 148-53. PMID 18555494 DOI: 10.1016/j.neuropharm.2008.05.002  0.96
2008 Pinna G, Agis-Balboa RC, Pibiri F, Nelson M, Guidotti A, Costa E. Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice. Neurochemical Research. 33: 1990-2007. PMID 18473173 DOI: 10.1007/s11064-008-9718-5  0.96
2008 Pibiri F, Nelson M, Guidotti A, Costa E, Pinna G. Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: A model relevant for posttraumatic stress disorder. Proceedings of the National Academy of Sciences of the United States of America. 105: 5567-72. PMID 18391192 DOI: 10.1073/pnas.0801853105  0.96
2007 Agís-Balboa RC, Pinna G, Pibiri F, Kadriu B, Costa E, Guidotti A. Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 18736-41. PMID 18003893 DOI: 10.1073/pnas.0709419104  0.96
2007 Costa E, Dong E, Grayson DR, Guidotti A, Ruzicka W, Veldic M. Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability. Epigenetics : Official Journal of the Dna Methylation Society. 2: 29-36. PMID 17965595  0.96
2007 Veldic M, Kadriu B, Maloku E, Agis-Balboa RC, Guidotti A, Davis JM, Costa E. Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder. Schizophrenia Research. 91: 51-61. PMID 17270400 DOI: 10.1016/j.schres.2006.11.029  0.96
2007 Guidotti A, Ruzicka W, Grayson DR, Veldic M, Pinna G, Davis JM, Costa E. S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis. Neuroreport. 18: 57-60. PMID 17259861 DOI: 10.1097/WNR.0b013e32800fefd7  0.96
2007 Kundakovic M, Chen Y, Costa E, Grayson DR. DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. Molecular Pharmacology. 71: 644-53. PMID 17065238 DOI: 10.1124/mol.106.030635  0.96
2006 Sharma RP, Rosen C, Kartan S, Guidotti A, Costa E, Grayson DR, Chase K. Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: preliminary results from a clinical population. Schizophrenia Research. 88: 227-31. PMID 16996718 DOI: 10.1016/j.schres.2006.07.015  0.96
2006 Agís-Balboa RC, Pinna G, Zhubi A, Maloku E, Veldic M, Costa E, Guidotti A. Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 14602-7. PMID 16984997 DOI: 10.1073/pnas.0606544103  0.96
2006 Tueting P, Doueiri MS, Guidotti A, Davis JM, Costa E. Reelin down-regulation in mice and psychosis endophenotypes. Neuroscience and Biobehavioral Reviews. 30: 1065-77. PMID 16769115 DOI: 10.1016/j.neubiorev.2006.04.001  0.96
2006 Grayson DR, Chen Y, Costa E, Dong E, Guidotti A, Kundakovic M, Sharma RP. The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia. Pharmacology & Therapeutics. 111: 272-86. PMID 16574235 DOI: 10.1016/j.pharmthera.2005.01.007  0.96
2006 Pinna G, Agis-Balboa RC, Zhubi A, Matsumoto K, Grayson DR, Costa E, Guidotti A. Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation. Proceedings of the National Academy of Sciences of the United States of America. 103: 4275-80. PMID 16537521 DOI: 10.1073/pnas.0600329103  0.96
2006 Pinna G, Costa E, Guidotti A. Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake. Psychopharmacology. 186: 362-72. PMID 16432684 DOI: 10.1007/s00213-005-0213-2  0.96
2005 Matsumoto K, Guidotti A, Costa E. [Stress and sleep/emotional disorder: possible involvement of neurosteroid allopregnanolone]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 126: 107-12. PMID 16205012 DOI: JST.JSTAGE/fpj/126.107  0.96
2005 Sharma RP, Grayson DR, Guidotti A, Costa E. Chromatin, DNA methylation and neuron gene regulation--the purpose of the package. Journal of Psychiatry & Neuroscience : Jpn. 30: 257-63. PMID 16049569  0.96
2005 Matsumoto K, Pinna G, Puia G, Guidotti A, Costa E. Social isolation stress-induced aggression in mice: a model to study the pharmacology of neurosteroidogenesis. Stress (Amsterdam, Netherlands). 8: 85-93. PMID 16019600 DOI: 10.1080/10253890500159022  0.96
2005 Auta J, Costa E, Davis JM, Guidotti A. Imidazenil: an antagonist of the sedative but not the anticonvulsant action of diazepam. Neuropharmacology. 49: 425-9. PMID 15964602 DOI: 10.1016/j.neuropharm.2005.04.005  0.96
2005 Grayson DR, Jia X, Chen Y, Sharma RP, Mitchell CP, Guidotti A, Costa E. Reelin promoter hypermethylation in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 102: 9341-6. PMID 15961543 DOI: 10.1073/pnas.0503736102  0.96
2005 Guidotti A, Auta J, Davis JM, Dong E, Grayson DR, Veldic M, Zhang X, Costa E. GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology. 180: 191-205. PMID 15864560 DOI: 10.1007/s00213-005-2212-8  0.96
2005 Mitchell CP, Chen Y, Kundakovic M, Costa E, Grayson DR. Histone deacetylase inhibitors decrease reelin promoter methylation in vitro. Journal of Neurochemistry. 93: 483-92. PMID 15816871 DOI: 10.1111/j.1471-4159.2005.03040.x  0.96
2005 Tremolizzo L, Doueiri MS, Dong E, Grayson DR, Davis J, Pinna G, Tueting P, Rodriguez-Menendez V, Costa E, Guidotti A. Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biological Psychiatry. 57: 500-9. PMID 15737665 DOI: 10.1016/j.biopsych.2004.11.046  0.96
2005 Veldic M, Guidotti A, Maloku E, Davis JM, Costa E. In psychosis, cortical interneurons overexpress DNA-methyltransferase 1. Proceedings of the National Academy of Sciences of the United States of America. 102: 2152-7. PMID 15684088 DOI: 10.1073/pnas.0409665102  0.96
2005 Pinna G, Costa E, Guidotti A. Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 102: 2135-40. PMID 15677716 DOI: 10.1073/pnas.0409643102  0.96
2005 Noh JS, Sharma RP, Veldic M, Salvacion AA, Jia X, Chen Y, Costa E, Guidotti A, Grayson DR. DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures. Proceedings of the National Academy of Sciences of the United States of America. 102: 1749-54. PMID 15671176 DOI: 10.1073/pnas.0409648102  0.96
2005 Costa E, Guidotti A, Veldić M. Should allosteric positive modulators of GABA(A) receptors be tested in the treatment of schizophrenia? Schizophrenia Research. 73: 367-8. PMID 15653283 DOI: 10.1016/j.schres.2004.08.005  0.96
2004 Pinna G, Agis-Balboa RC, Doueiri MS, Guidotti A, Costa E. Brain neurosteroids in gender-related aggression induced by social isolation. Critical Reviews in Neurobiology. 16: 75-82. PMID 15581402 DOI: 10.1615/CritRevNeurobiol.v16.i12.80  0.96
2004 Pinna G, Costa E, Guidotti A. Fluoxetine and norfluoxetine stereospecifically facilitate pentobarbital sedation by increasing neurosteroids. Proceedings of the National Academy of Sciences of the United States of America. 101: 6222-5. PMID 15069199 DOI: 10.1073/pnas.0401479101  0.96
2004 Auta J, Costa E, Davis J, Guidotti A. Imidazenil: a potent and safe protective agent against diisopropyl fluorophosphate toxicity. Neuropharmacology. 46: 397-403. PMID 14975695 DOI: 10.1016/j.neuropharm.2003.09.010  0.96
2003 Costa E, Grayson DR, Guidotti A. Epigenetic downregulation of GABAergic function in schizophrenia: potential for pharmacological intervention? Molecular Interventions. 3: 220-9. PMID 14993449 DOI: 10.1124/mi.3.4.220  0.96
2003 Costa E, Grayson DR, Mitchell CP, Tremolizzo L, Veldic M, Guidotti A. GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability. Critical Reviews in Neurobiology. 15: 121-42. PMID 14977367 DOI: 10.1615/CritRevNeurobiol.v15.i2.20  0.96
2003 Dong E, Caruncho H, Liu WS, Smalheiser NR, Grayson DR, Costa E, Guidotti A. A reelin-integrin receptor interaction regulates Arc mRNA translation in synaptoneurosomes. Proceedings of the National Academy of Sciences of the United States of America. 100: 5479-84. PMID 12707415 DOI: 10.1073/pnas.1031602100  0.96
2003 Larson J, Hoffman JS, Guidotti A, Costa E. Olfactory discrimination learning deficit in heterozygous reeler mice. Brain Research. 971: 40-6. PMID 12691835 DOI: 10.1016/S0006-8993(03)02353-9  0.96
2003 Pinna G, Dong E, Matsumoto K, Costa E, Guidotti A. In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine. Proceedings of the National Academy of Sciences of the United States of America. 100: 2035-40. PMID 12571361 DOI: 10.1073/pnas.0337642100  0.96
2002 Rodriguez MA, Caruncho HJ, Costa E, Pesold C, Liu WS, Guidotti A. In Patas monkey, glutamic acid decarboxylase-67 and reelin mRNA coexpression varies in a manner dependent on layers and cortical areas. The Journal of Comparative Neurology. 451: 279-88. PMID 12210139 DOI: 10.1002/cne.10341  0.96
2002 Chen Y, Sharma RP, Costa RH, Costa E, Grayson DR. On the epigenetic regulation of the human reelin promoter. Nucleic Acids Research. 30: 2930-9. PMID 12087179 DOI: 10.1093/nar/gkf401  0.96
2002 Costa E, Davis J, Pesold C, Tueting P, Guidotti A. The heterozygote reeler mouse as a model for the development of a new generation of antipsychotics. Current Opinion in Pharmacology. 2: 56-62. PMID 11786309 DOI: 10.1016/S1471-4892(01)00121-7  0.96
Show low-probability matches.