James E. Zadina - Publications

Affiliations: 
Tulane University, New Orleans, LA, United States 
Area:
peptides, endomorphins, pain, reward

151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Feehan AK, Zadina JE. Morphine immunomodulation prolongs inflammatory and postoperative pain while the novel analgesic ZH853 accelerates recovery and protects against latent sensitization. Journal of Neuroinflammation. 16: 100. PMID 31109346 DOI: 10.1186/s12974-019-1480-x  1
2017 Feehan AK, Morgenweck J, Zhang X, Amgott-Kwan A, Zadina JE. Novel Endomorphin Analogs are More Potent and Longer Lasting Analgesics in Neuropathic, Postoperative, Inflammatory, and Visceral Pain Relative to Morphine. The Journal of Pain : Official Journal of the American Pain Society. PMID 28939014 DOI: 10.1016/j.jpain.2017.08.007  1
2015 Zadina JE, Nilges MR, Morgenweck J, Zhang X, Hackler L, Fasold MB. Endomorphin Analog Analgesics with Reduced Abuse Liability, Respiratory Depression, Motor Impairment, Tolerance, and Glial Activation. Neuropharmacology. PMID 26748051 DOI: 10.1016/j.neuropharm.2015.12.024  1
2015 Nasirinezhad F, Gajavelli S, Priddy B, Jergova S, Zadina J, Sagen J. Viral vectors encoding endomorphins and serine histogranin attenuate neuropathic pain symptoms after spinal cord injury in rats. Molecular Pain. 11: 2. PMID 25563474 DOI: 10.1186/1744-8069-11-2  1
2013 Morgenweck J, Griggs RB, Donahue RR, Zadina JE, Taylor BK. PPARγ activation blocks development and reduces established neuropathic pain in rats. Neuropharmacology. 70: 236-46. PMID 23415633 DOI: 10.1016/j.neuropharm.2013.01.020  1
2012 Chakrabarti S, Liu NJ, Zadina JE, Sharma T, Gintzler AR. Pleiotropic opioid regulation of spinal endomorphin 2 release and its adaptations to opioid withdrawal are sexually dimorphic. The Journal of Pharmacology and Experimental Therapeutics. 340: 56-63. PMID 21972236 DOI: 10.1124/jpet.111.186874  1
2011 Stewart A, Wu N, Cachat J, Hart P, Gaikwad S, Wong K, Utterback E, Gilder T, Kyzar E, Newman A, Carlos D, Chang K, Hook M, Rhymes C, Caffery M, ... ... Zadina J, et al. Pharmacological modulation of anxiety-like phenotypes in adult zebrafish behavioral models. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 1421-31. PMID 21122812 DOI: 10.1016/j.pnpbp.2010.11.035  1
2010 Funkelstein L, Beinfeld M, Minokadeh A, Zadina J, Hook V. Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides. Neuropeptides. 44: 457-66. PMID 21047684 DOI: 10.1016/j.npep.2010.08.003  1
2010 Corder G, Siegel A, Intondi AB, Zhang X, Zadina JE, Taylor BK. A novel method to quantify histochemical changes throughout the mediolateral axis of the substantia gelatinosa after spared nerve injury: characterization with TRPV1 and substance P. The Journal of Pain : Official Journal of the American Pain Society. 11: 388-98. PMID 20350706 DOI: 10.1016/j.jpain.2009.09.008  1
2010 Intondi AB, Zadina JE, Zhang X, Taylor BK. Topography and time course of changes in spinal neuropeptide Y immunoreactivity after spared nerve injury. Neuroscience. 165: 914-22. PMID 19879928 DOI: 10.1016/j.neuroscience.2009.10.052  1
2010 Minokadeh A, Funkelstein L, Toneff T, Hwang SR, Beinfeld M, Reinheckel T, Peters C, Zadina J, Hook V. Cathepsin L participates in dynorphin production in brain cortex, illustrated by protease gene knockout and expression. Molecular and Cellular Neurosciences. 43: 98-107. PMID 19837164 DOI: 10.1016/j.mcn.2009.10.001  1
2008 Greco MA, Fuller PM, Jhou TC, Martin-Schild S, Zadina JE, Hu Z, Shiromani P, Lu J. Opioidergic projections to sleep-active neurons in the ventrolateral preoptic nucleus. Brain Research. 1245: 96-107. PMID 18840417 DOI: 10.1016/j.brainres.2008.09.043  1
2008 Guo N, Garcia MM, Taylor BK, Zadina JE, Harlan RE. Blockade of micro-opioid receptors in the medial thalamus inhibits acquisition, but not expression, of morphine-induced conditioned place preference. Neuroscience. 151: 948-54. PMID 18222040 DOI: 10.1016/j.neuroscience.2007.10.058  1
2007 Greenwell TN, Martin-Schild S, Inglis FM, Zadina JE. Colocalization and shared distribution of endomorphins with substance P, calcitonin gene-related peptide, gamma-aminobutyric acid, and the mu opioid receptor. The Journal of Comparative Neurology. 503: 319-33. PMID 17492626 DOI: 10.1002/cne.21374  1
2005 Czapla MA, Zadina JE. Reduced suppression of CO2-induced ventilatory stimulation by endomorphins relative to morphine. Brain Research. 1059: 159-66. PMID 16223471 DOI: 10.1016/j.brainres.2005.08.020  1
2005 Silverman MB, Hermes SM, Zadina JE, Aicher SA. Mu-opioid receptor is present in dendritic targets of Endomorphin-2 axon terminals in the nuclei of the solitary tract. Neuroscience. 135: 887-96. PMID 16154285 DOI: 10.1016/j.neuroscience.2005.06.072  1
2005 Dorfman HN, Bailey AL, St Louis M, Zadina JE, Ribeiro-da-Silva A. Postnatal development of ectopic sensory fibers containing endomorphin-2 in the white matter of the spinal cord of a transgenic mouse expressing nerve growth factor in oligodendrocytes. Neuroscience. 134: 1205-16. PMID 16039798 DOI: 10.1016/j.neuroscience.2005.05.026  1
2004 Horner KA, Zadina JE. Internalization and down-regulation of mu opioid receptors by endomorphins and morphine in SH-SY5Y human neuroblastoma cells. Brain Research. 1028: 121-32. PMID 15527737 DOI: 10.1016/j.brainres.2004.07.055  1
2004 Somogyvari-Vigh A, Kastin AJ, Liao J, Zadina JE, Pan W. Endomorphins exit the brain by a saturable efflux system at the basolateral surface of cerebral endothelial cells. Experimental Brain Research. 156: 224-30. PMID 15344852 DOI: 10.1007/s00221-003-1774-0  1
2004 Soignier RD, Vaccarino AL, Fanti KA, Wilson AM, Zadina JE. Analgesic tolerance and cross-tolerance to i.c.v. endomorphin-1, endomorphin-2, and morphine in mice. Neuroscience Letters. 366: 211-4. PMID 15276249 DOI: 10.1016/j.neulet.2004.05.046  1
2003 Aicher SA, Mitchell JL, Swanson KC, Zadina JE. Endomorphin-2 axon terminals contact mu-opioid receptor-containing dendrites in trigeminal dorsal horn. Brain Research. 977: 190-8. PMID 12834879 DOI: 10.1016/S0006-8993(03)02678-7  1
2003 Wang QP, Zadina JE, Guan JL, Shioda S. Morphological evidence of endomorphin as an agonist for the mu-opioid receptor in the rat spinal cord. Neuroscience Letters. 341: 107-10. PMID 12686377 DOI: 10.1016/S0304-3940(03)00182-4  1
2003 Wang QP, Zadina JE, Guan JL, Kastin AJ, Shioda S. Electron microscopic examination of the endomorphin 2-like immunoreactive neurons in the rat hypothalamus. Brain Research. 969: 126-34. PMID 12676373 DOI: 10.1016/S0006-8993(03)02290-X  1
2002 Greenwell TN, Zangen A, Martin-Schild S, Wise RA, Zadina JE. Endomorphin-1 and -2 immunoreactive cells in the hypothalamus are labeled by fluoro-gold injections to the ventral tegmental area. The Journal of Comparative Neurology. 454: 320-8. PMID 12442322 DOI: 10.1002/cne.10464  1
2002 Abbadie C, Rossi GC, Orciuolo A, Zadina JE, Pasternak GW. Anatomical and functional correlation of the endomorphins with mu opioid receptor splice variants. The European Journal of Neuroscience. 16: 1075-82. PMID 12383236 DOI: 10.1046/j.1460-9568.2002.02173.x  1
2002 Lioudyno MI, Verbitsky M, Glowatzki E, Holt JC, Boulter J, Zadina JE, Elgoyhen AB, Guth PS. The alpha9/alpha10-containing nicotinic ACh receptor is directly modulated by opioid peptides, endomorphin-1, and dynorphin B, proposed efferent cotransmitters in the inner ear. Molecular and Cellular Neurosciences. 20: 695-711. PMID 12213449 DOI: 10.1006/mcne.2002.1150  1
2002 Wang QP, Zadina JE, Guan JL, Shioda S. Morphological studies of the endomorphinergic neurons in the central nervous system. Japanese Journal of Pharmacology. 89: 209-15. PMID 12184723 DOI: 10.1254/jjp.89.209  1
2002 Zadina JE. Isolation and distribution of endomorphins in the central nervous system. Japanese Journal of Pharmacology. 89: 203-8. PMID 12184722 DOI: 10.1254/jjp.89.203  1
2002 Zangen A, Ikemoto S, Zadina JE, Wise RA. Rewarding and psychomotor stimulant effects of endomorphin-1: anteroposterior differences within the ventral tegmental area and lack of effect in nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7225-33. PMID 12177217  1
2002 Wang QP, Zadina JE, Guan JL, Kastin AJ, Funahashi H, Shioda S. Endomorphin-2 immunoreactivity in the cervical dorsal horn of the rat spinal cord at the electron microscopic level. Neuroscience. 113: 593-605. PMID 12150779 DOI: 10.1016/S0306-4522(02)00153-7  1
2002 Sakurada S, Hayashi T, Yuhki M, Fujimura T, Murayama K, Yonezawa A, Sakurada C, Takeshita M, Sato T, Zadina JE, Kastin AJ, Sakurada T. Differential antagonism of endomorphin-1 and endomorphin-2 supraspinal antinociception by naloxonazine and 3-methylnaltrexone. Peptides. 23: 895-901. PMID 12084520 DOI: 10.1016/S0196-9781(02)00016-5  1
2002 Champion HC, Bivalacqua TJ, Zadina JE, Kastin AJ, Hyman AL, Kadowitz PJ. Role of nitric oxide in mediating vasodilator responses to opioid peptides in the rat. Clinical and Experimental Pharmacology & Physiology. 29: 229-32. PMID 11906489 DOI: 10.1046/j.1440-1681.2002.03634.x  1
2002 Kastin AJ, Fasold MB, Zadina JE. Endomorphins, Met-enkephalin, Tyr-MIF-1, and the P-glycoprotein efflux system. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 231-4. PMID 11854138 DOI: 10.1124/dmd.30.3.231  1
2001 McLay RN, Freeman SM, Zadina JE. Administration of FGF-1 through transfected cells alleviates MPTP toxicity in mice. Neurotoxicity Research. 3: 249-53. PMID 15111249  1
2001 Whitten RD, Martin-Schild S, Zadina JE, Albers HE. Endomorphin1-like immunoreactivity in the limbic system of Syrian hamsters (Mesocricetus auratus). Brain Research Bulletin. 56: 563-7. PMID 11786242 DOI: 10.1016/S0361-9230(01)00644-X  1
2001 Oude Elferink RP, Zadina J. MDR1 P-glycoprotein transports endogenous opioid peptides Peptides. 22: 2015-2020. PMID 11786185  1
2001 Whitten RD, Jasnow AM, Albers HE, Martin-Schild S, Zadina JE, Huhman KL. The effects of endomorphin-1 on conditioned defeat in Syrian hamsters (Mesocricetus auratus). Brain Research. 914: 74-80. PMID 11578599 DOI: 10.1016/S0006-8993(01)02775-5  1
2001 Sakurada S, Hayashi T, Yuhki M, Orito T, Zadina JE, Kastin AJ, Fujimura T, Murayama K, Sakurada C, Sakurada T, Narita M, Suzuki T, Tan-no K, Tseng LF. Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse. European Journal of Pharmacology. 427: 203-10. PMID 11567650 DOI: 10.1016/S0014-2999(01)01238-9  1
2001 Kastin AJ, Hahn K, Zadina JE. Regional differences in peptide degradation by rat cerebral microvessels: a potential novel regulatory mechanism for communication between blood and brain. Life Sciences. 69: 1305-12. PMID 11521754 DOI: 10.1016/S0024-3205(01)01211-5  1
2001 Smith RR, Martin-Schild S, Kastin AJ, Zadina JE. Decreases in endomorphin-2-like immunoreactivity concomitant with chronic pain after nerve injury. Neuroscience. 105: 773-8. PMID 11516840 DOI: 10.1016/S0306-4522(01)00228-7  1
2001 Kastin AJ, Fasold MB, Smith RR, Horner KA, Zadina JE. Saturable brain-to-blood transport of endomorphins. Experimental Brain Research. 139: 70-5. PMID 11482845 DOI: 10.1007/s002210100736  1
2001 Maresh GA, Maness LM, Zadina JE, Kastin AJ. In vitro demonstration of a saturable transport system for leptin across the blood-brain barrier. Life Sciences. 69: 67-73. PMID 11411806 DOI: 10.1016/S0024-3205(01)01093-1  1
2000 Wilson AM, Soignier RD, Zadina JE, Kastin AJ, Nores WL, Olson RD, Olson GA. Dissociation of analgesic and rewarding effects of endomorphin-1 in rats. Peptides. 21: 1871-4. PMID 11150648 DOI: 10.1016/S0196-9781(00)00340-5  1
2000 McLay RN, Kastin AJ, Zadina JE. Passage of interleukin-1-beta across the blood-brain barrier is reduced in aged mice: a possible mechanism for diminished fever in aging. Neuroimmunomodulation. 8: 148-53. PMID 11124581 DOI: 10.1159/000054275  1
2000 Sakurada S, Hayashi T, Yuhki M, Fujimura T, Murayama K, Yonezawa A, Sakurada C, Takeshita M, Zadina JE, Kastin AJ, Sakurada T. Differential antagonism of endomorphin-1 and endomorphin-2 spinal antinociception by naloxonazine and 3-methoxynaltrexone. Brain Research. 881: 1-8. PMID 11033087 DOI: 10.1016/S0006-8993(00)02770-0  1
2000 Czapla MA, Gozal D, Alea OA, Beckerman RC, Zadina JE. Differential cardiorespiratory effects of endomorphin 1, endomorphin 2, DAMGO, and morphine. American Journal of Respiratory and Critical Care Medicine. 162: 994-9. PMID 10988119 DOI: 10.1164/ajrccm.162.3.9911102  1
2000 Soignier RD, Vaccarino AL, Brennan AM, Kastin AJ, Zadina JE. Analgesic effects of endomorphin-1 and endomorphin-2 in the formalin test in mice. Life Sciences. 67: 907-12. PMID 10946850 DOI: 10.1016/S0024-3205(00)00689-5  1
2000 Kastin AJ, Akerstrom V, Hackler L, Zadina JE. Phe(13),Tyr(19)-melanin-concentration hormone and the blood-brain barrier: role of protein binding. Journal of Neurochemistry. 74: 385-91. PMID 10617143 DOI: 10.1046/j.1471-4159.2000.0740385.x  1
1999 Barr GA, Zadina JE. Maturation of endomorphin-2 in the dorsal horn of the medulla and spinal cord of the rat. Neuroreport. 10: 3857-60. PMID 10716223  1
1999 Nachman RJ, Moyna G, Williams HJ, Zabrocki J, Zadina JE, Coast GM, Varden Broeck J. Comparison of active conformations of the insectatachykinin/tachykinin and insect kinin/Tyr-W-MIF-1 neuropeptide family pairs. Annals of the New York Academy of Sciences. 897: 388-400. PMID 10676465  1
1999 Champion HC, Bivalacqua TJ, Zadina JE, Kastin AJ, Kadowitz PJ. Vasodilator responses to the endomorphin peptides, but not nociceptin/OFQ, are mediated by nitric oxide release. Annals of the New York Academy of Sciences. 897: 165-72. PMID 10676445  1
1999 Barr GA, Zadina JE. The ontogeny of endomorphin-1- and endomorphin-2-like immunoreactivity in rat brain and spinal cord. Annals of the New York Academy of Sciences. 897: 145-53. PMID 10676443  1
1999 Zadina JE, Martin-Schild S, Gerall AA, Kastin AJ, Hackler L, Ge LJ, Zhang X. Endomorphins: novel endogenous mu-opiate receptor agonists in regions of high mu-opiate receptor density. Annals of the New York Academy of Sciences. 897: 136-44. PMID 10676442  1
1999 Maresh GA, Kastin AJ, Brown TT, Zadina JE, Banks WA. Peptide transport system-1 (PTS-1) for Tyr-MIF-1 and Met-enkephalin differs from the receptors for either. Brain Research. 839: 336-40. PMID 10519058 DOI: 10.1016/S0006-8993(99)01755-2  1
1999 Bell RL, Vaccarino AL, Olson RD, Olson GA, Nores WL, Cambre JG, Zadina JE, Kastin AJ. Tolerance and morphine-induced cross-tolerance are not shown to Tyr-W-MIF-1 analgesia. Peptides. 20: 971-8. PMID 10503776 DOI: 10.1016/S0196-9781(99)00090-X  1
1999 Pan W, Kastin AJ, Banks WA, Zadina JE. Effects of peptides: a cross-listing of peptides and their central actions published in the journal Peptides from 1994 through 1998. Peptides. 20: 1127-38. PMID 10499432 DOI: 10.1016/S0196-9781(99)00109-6  1
1999 Nores WL, Olson RD, Olson GA, Vaccarino AL, Bell RL, Zadina JE, Kastin AJ. Tyr-W-MIF-1-induced conditioned place preference. Peptides. 20: 479-84. PMID 10458518 DOI: 10.1016/S0196-9781(99)00029-7  1
1999 Sakurada S, Zadina JE, Kastin AJ, Katsuyama S, Fujimura T, Murayama K, Yuki M, Ueda H, Sakurada T. Differential involvement of mu-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception. European Journal of Pharmacology. 372: 25-30. PMID 10374711 DOI: 10.1016/S0014-2999(99)00181-8  1
1999 McLay RN, Freeman SM, Harlan RE, Kastin AJ, Zadina JE. Tests used to assess the cognitive abilities of aged rats: their relation to each other and to hippocampal morphology and neurotrophin expression. Gerontology. 45: 143-55. PMID 10202259 DOI: 10.1159/000022077  1
1999 Martin-Schild S, Gerall AA, Kastin AJ, Zadina JE. Differential distribution of endomorphin 1- and endomorphin 2-like immunoreactivities in the CNS of the rodent. The Journal of Comparative Neurology. 405: 450-71. PMID 10098939 DOI: 10.1002/(SICI)1096-9861(19990322)405:4<450::AID-CNE2>3.0.CO;2-#  1
1998 Martin-Schild S, Gerall AA, Kastin AJ, Zadina JE. Endomorphin-2 is an endogenous opioid in primary sensory afferent fibers. Peptides. 19: 1783-9. PMID 9880085 DOI: 10.1016/S0196-9781(98)00136-3  1
1998 Harrison LM, Kastin AJ, Zadina JE. Opiate tolerance and dependence: receptors, G-proteins, and antiopiates. Peptides. 19: 1603-30. PMID 9864069 DOI: 10.1016/S0196-9781(98)00126-0  1
1998 Champion HC, Bivalacqua TJ, Friedman DE, Zadina JE, Kastin AJ, Kadowitz PJ. Nitric oxide release mediates vasodilator responses to endomorphin 1 but not nociceptin/OFQ in the hindquarters vascular bed of the rat. Peptides. 19: 1595-602. PMID 9864068 DOI: 10.1016/S0196-9781(98)00110-7  1
1998 Champion HC, Bivalacqua TJ, Lambert DG, McWilliams SM, Zadina JE, Kastin AJ, Kadowitz PJ. Endomorphin 1 and 2, the endogenous mu-opioid agonists, produce biphasic changes in systemic arterial pressure in the cat. Life Sciences. 63: PL131-6. PMID 9740318  1
1998 Wu GD, Graf JA, Zadina JE, Chang SL. The expression of interleukin-1-beta converting enzyme (ICE) in rat is decreased following chronic exposure to morphine. Advances in Experimental Medicine and Biology. 437: 51-8. PMID 9666256  1
1998 Champion HC, Zadina JE, Kastin AJ, Kadowitz PJ. Endomorphin 1 and 2 have vasodepressor activity in the anesthetized mouse. Peptides. 19: 925-9. PMID 9663459 DOI: 10.1016/S0196-9781(98)00026-6  1
1998 Harrison LM, Kastin AJ, Zadina JE. Differential effects of endomorphin-1, endomorphin-2, and Tyr-W-MIF-1 on activation of G-proteins in SH-SY5Y human neuroblastoma membranes. Peptides. 19: 749-53. PMID 9622031 DOI: 10.1016/S0196-9781(98)00022-9  1
1998 McLay RN, Freeman SM, Zadina JE. Chronic corticosterone impairs memory performance in the Barnes maze. Physiology & Behavior. 63: 933-7. PMID 9618019 DOI: 10.1016/S0031-9384(97)00529-5  1
1998 Czapla MA, Champion HC, Zadina JE, Kastin AJ, Hackler L, Ge LJ, Kadowitz PJ. Endomorphin 1 and 2, endogenous mu-opioid agonists, decrease systemic arterial pressure in the rat. Life Sciences. 62: PL175-9. PMID 9519803 DOI: 10.1016/S0024-3205(98)00048-4  1
1998 Higashida H, Hoshi N, Knijnik R, Zadina JE, Kastin AJ. Endomorphins inhibit high-threshold Ca2+ channel currents in rodent NG108-15 cells overexpressing mu-opioid receptors. The Journal of Physiology. 507: 71-5. PMID 9490819 DOI: 10.1111/j.1469-7793.1998.071bu.x  1
1998 Harrison LM, Kastin AJ, Zadina JE. Tyr-W-MIF-1 attenuates down-regulation of opiate receptors in SH-SY5Y human neuroblastoma cells. The Journal of Pharmacology and Experimental Therapeutics. 284: 611-7. PMID 9454805  1
1998 Kastin AJ, Hahn K, Banks WA, Zadina JE. Regional differences in the metabolism of Tyr-MIF-1 and Tyr-W-MIF-1 by rat brain mitochondria. Biochemical Pharmacology. 55: 33-6. PMID 9413927 DOI: 10.1016/S0006-2952(97)00376-6  1
1997 Martin-Schild S, Zadina JE, Gerall AA, Vigh S, Kastin AJ. Localization of endomorphin-2-like immunoreactivity in the rat medulla and spinal cord. Peptides. 18: 1641-9. PMID 9437728 DOI: 10.1016/S0196-9781(97)00320-3  1
1997 Hackler L, Zadina JE, Ge LJ, Kastin AJ. Isolation of relatively large amounts of endomorphin-1 and endomorphin-2 from human brain cortex. Peptides. 18: 1635-9. PMID 9437727 DOI: 10.1016/S0196-9781(97)00259-3  1
1997 Champion HC, Zadina JE, Kastin AJ, Kadowitz PJ. The endogenous mu-opioid agonists, endomorphin 1 and 2, have vasodilator activity in the hindquarters vascular bed of the rat. Life Sciences. 61: PL 409-15. PMID 9416782 DOI: 10.1016/S0024-3205(97)01029-1  1
1997 Champion HC, Zadina JE, Kastin AJ, Hackler L, Ge LJ, Kadowitz PJ. Endomorphin 1 and 2, endogenous ligands for the mu-opioid receptor, decrease cardiac output, and total peripheral resistance in the rat. Peptides. 18: 1393-7. PMID 9392842 DOI: 10.1016/S0196-9781(97)00210-6  1
1997 McLay RN, Freeman SM, Harlan RE, Ide CF, Kastin AJ, Zadina JE. Aging in the hippocampus: interrelated actions of neurotrophins and glucocorticoids. Neuroscience and Biobehavioral Reviews. 21: 615-29. PMID 9353795 DOI: 10.1016/S0149-7634(96)00046-2  1
1997 Pan W, Zadina JE, Harlan RE, Weber JT, Banks WA, Kastin AJ. Tumor necrosis factor-alpha: a neuromodulator in the CNS. Neuroscience and Biobehavioral Reviews. 21: 603-13. PMID 9353794 DOI: 10.1016/S0149-7634(96)00047-4  1
1997 Champion HC, Zadina JE, Kastin AJ, Hackler L, Ge LJ, Kadowitz PJ. The endogenous mu-opioid receptor agonists endomorphins 1 and 2 have novel hypotensive activity in the rabbit. Biochemical and Biophysical Research Communications. 235: 567-70. PMID 9207197 DOI: 10.1006/bbrc.1997.6843  1
1997 Zadina JE, Hackler L, Ge LJ, Kastin AJ. A potent and selective endogenous agonist for the mu-opiate receptor. Nature. 386: 499-502. PMID 9087409 DOI: 10.1038/386499a0  1
1996 Gergen KA, Zadina JE, Paul D. Analgesic effects of Tyr-W-MIF-1: a mixed mu2-opioid receptor agonist/mu1-opioid receptor antagonist. European Journal of Pharmacology. 316: 33-8. PMID 8982647 DOI: 10.1016/S0014-2999(96)00656-5  1
1996 Banks WA, Kastin AJ, Harrison LM, Zadina JE. Perinatal treatment of rats with opiates affects the development of the blood-brain barrier transport system PTS-1. Neurotoxicology and Teratology. 18: 711-5. PMID 8947949 DOI: 10.1016/S0892-0362(96)00128-6  1
1996 Chang SL, Patel NA, Romero AA, Thompson J, Zadina JE. FOS expression induced by interleukin-1 or acute morphine treatment in the rat hypothalamus is attenuated by chronic exposure to morphine. Brain Research. 736: 227-36. PMID 8930328 DOI: 10.1016/0006-8993(96)00698-1  1
1996 Zadina JE, Paul D, Gergen KA, Ge LJ, Hackler L, Kastin AJ. Binding of Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2) and related peptides to mu 1 and mu 2 opiate receptors. Neuroscience Letters. 215: 65-9. PMID 8880755 DOI: 10.1016/S0304-3940(96)12928-1  1
1996 Gergen KA, Zadina JE, Kastin AJ, Paul D. Intrathecal Tyr-W-MIF-1 produces potent, naloxone-reversible analgesia modulated by alpha 2-adrenoceptors. European Journal of Pharmacology. 298: 235-9. PMID 8846821 DOI: 10.1016/0014-2999(95)00823-3  1
1996 Patel NA, Romero AA, Zadina JE, Chang SL. Chronic exposure to morphine attenuates expression of interleukin-1 beta in the rat hippocampus. Brain Research. 712: 340-4. PMID 8814911 DOI: 10.1016/0006-8993(95)01575-2  1
1996 Maness LM, Banks WA, Zadina JE, Kastin AJ. Periventricular penetration and disappearance of ICV Tyr-MIF-1, DAMGO, tyrosine, and albumin. Peptides. 17: 247-50. PMID 8801529 DOI: 10.1016/0196-9781(95)02135-3  1
1996 Chang SL, Moldow RL, House SD, Zadina JE. Morphine affects the brain-immune axis by modulating an interleukin-1 beta dependent pathway. Advances in Experimental Medicine and Biology. 402: 35-42. PMID 8787641  1
1996 Kastin AJ, Zadina JE, Olson RD, Banks WA. The history of neuropeptide research: version 5.a. Annals of the New York Academy of Sciences. 780: 1-18. PMID 8602723 DOI: 10.1111/j.1749-6632.1996.tb15107.x  1
1995 Maness LM, Banks WA, Zadina JE, Kastin AJ. Selective transport of blood-borne interleukin-1 alpha into the posterior division of the septum of the mouse brain. Brain Research. 700: 83-8. PMID 8624731 DOI: 10.1016/0006-8993(95)00913-B  1
1995 Kastin AJ, Hahn K, Zadina JE, Banks WA, Hackler L. Melanocyte-stimulating hormone release-inhibiting factor-1 (MIF-1) can be formed from Tyr-MIF-1 in brain mitochondria but not in brain homogenate. Journal of Neurochemistry. 64: 1855-9. PMID 7891114  1
1995 Kastin AJ, Fabre L, Banks WA, Hackler L, Zadina JE. Increase in plasma TYR-MIF-1-like immunoreactivity after hypophysectomy is robust and reversible by corticosterone. Neuropeptides. 28: 65-71. PMID 7746353 DOI: 10.1016/0143-4179(95)90076-4  1
1995 Chang SL, Kenigs V, Moldow RL, Zadina JE. Chronic treatment with morphine and ethanol, but not cocaine, attenuates IL-1 beta activation of FOS expression in the rat hypothalamic paraventricular nucleus. Advances in Experimental Medicine and Biology. 373: 201-8. PMID 7668153  1
1995 Zadina JE, Kastin AJ, Harrison LM, Ge LJ, Chang SL. Opiate receptor changes after chronic exposure to agonists and antagonists. Annals of the New York Academy of Sciences. 757: 353-61. PMID 7611692 DOI: 10.1111/j.1749-6632.1995.tb17493.x  1
1994 Maness LM, Kastin AJ, Weber JT, Banks WA, Beckman BS, Zadina JE. The neurotrophins and their receptors: structure, function, and neuropathology. Neuroscience and Biobehavioral Reviews. 18: 143-59. PMID 8170621 DOI: 10.1016/0149-7634(94)90043-4  1
1994 Hackler L, Kastin AJ, Zadina JE. Isolation of a novel peptide with a unique binding profile from human brain cortex: Tyr-K-MIF-1 (Tyr-Pro-Lys-Gly-NH2). Peptides. 15: 945-50. PMID 7991457 DOI: 10.1016/0196-9781(94)90056-6  1
1994 Ahmed B, Kastin AJ, Banks WA, Zadina JE. CNS effects of peptides: a cross-listing of peptides and their central actions published in the journal Peptides, 1986-1993. Peptides. 15: 1105-55. PMID 7991456 DOI: 10.1016/0196-9781(94)90078-7  1
1994 Zadina JE, Kastin AJ, Ge LJ, Hackler L. Mu, delta, and kappa opiate receptor binding of Tyr-MIF-1 and of Tyr-W-MIF-1, its active fragments, and two potent analogs. Life Sciences. 55: PL461-6. PMID 7990646 DOI: 10.1016/0024-3205(94)00533-8  1
1994 Kastin AJ, Banks WA, Hahn K, Zadina JE. Extreme stability of Tyr-MIF-1 in CSF. Neuroscience Letters. 174: 26-8. PMID 7970149 DOI: 10.1016/0304-3940(94)90110-4  1
1994 Zadina JE, Harrison LM, Ge LJ, Kastin AJ, Chang SL. Differential regulation of mu and delta opiate receptors by morphine, selective agonists and antagonists and differentiating agents in SH-SY5Y human neuroblastoma cells. The Journal of Pharmacology and Experimental Therapeutics. 270: 1086-96. PMID 7932156  1
1994 Kastin AJ, Hahn K, Erchegyi J, Zadina JE, Hackler L, Palmgren M, Banks WA. Differential metabolism of Tyr-MIF-1 and MIF-1 in rat and human plasma. Biochemical Pharmacology. 47: 699-709. PMID 7907473 DOI: 10.1016/0006-2952(94)90133-3  1
1994 Harrison LM, Kastin AJ, Weber JT, Banks WA, Hurley DL, Zadina JE. The opiate system in invertebrates. Peptides. 15: 1309-29. PMID 7854985 DOI: 10.1016/0196-9781(94)90159-7  1
1994 Kastin AJ, Banks WA, Olson RD, Zadina JE. Novel concepts from novel peptides. Annals of the New York Academy of Sciences. 739: 1-10. PMID 7832462  1
1994 Zadina JE, Kastin AJ, Hackler L, Chang SL. Cyclic analogues of Tyr-W-MIF-1 with prolonged analgesic activity and potency comparable to DAMGO and morphine. Peptides. 15: 1567-9. PMID 7700858 DOI: 10.1016/0196-9781(94)90135-X  1
1994 Kastin AJ, Hahn K, Banks WA, Zadina JE. Delayed degradation of Tyr-MIF-1 in neonatal rat plasma. Peptides. 15: 1561-3. PMID 7700856 DOI: 10.1016/0196-9781(94)90133-3  1
1994 Gergen KA, Chang SL, Niu YF, Kastin AJ, Zadina JE. Expression of the FOS proto-oncogene protein in brain after ICV administration of Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2). Peptides. 15: 1505-11. PMID 7700853 DOI: 10.1016/0196-9781(94)90130-9  1
1994 Zadina JE, Kastin AJ, Hackler L, Ge LJ, Kenigs V, Gergen KA, Messenger KA, Chang SL. Opiate receptor binding, guinea pig ileum activity, and prolonged analgesia induced by the brain peptide Tyr-W-MIF-1 and two potent analogs Regulatory Peptides. 54: 341-342. DOI: 10.1016/0167-0115(94)90528-2  1
1994 Chang SL, Zadina JE, Niu YF, Thompson J. Morphine modulates IL-1 activation of fos in the rat hypothalamus Regulatory Peptides. 53: S265-S266. DOI: 10.1016/0167-0115(94)90341-7  1
1994 Zadina JE, Kastin AJ, Ge LJ, Chang SL. Novel peptides and mechanisms of opiate tolerance Regulatory Peptides. 53: S195-S196. DOI: 10.1016/0167-0115(94)90307-7  1
1993 Chang SL, Zadina JE, Spriggs L, Squinto SP. Prolonged Activation of c-fos and Optimal Activation of Pro-opiomelanocortin mRNA after Repeated Morphine Exposure in SH-SY5Y Cells. Molecular and Cellular Neurosciences. 4: 25-9. PMID 19912904 DOI: 10.1006/mcne.1993.1003  1
1993 Chang SL, Ren T, Zadina JE. Interleukin-1 activation of FOS proto-oncogene protein in the rat hypothalamus. Brain Research. 617: 123-30. PMID 8374734 DOI: 10.1016/0006-8993(93)90622-T  1
1993 Zadina JE, Kastin AJ, Kenigs V, Bruno C, Hackler L. Prolonged analgesia after intracerebroventricular Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2). Neuroscience Letters. 155: 220-2. PMID 8104325 DOI: 10.1016/0304-3940(93)90712-T  1
1993 Kastin AJ, Fabre L, Banks WA, Zadina JE. Uptake, content, regulation of plasma concentrations, and binding of Tyr-MIF-1 by the adrenals. Neuroendocrinology. 57: 541-9. PMID 8100620 DOI: 10.1159/000126403  1
1993 Malin DR, Zadina JE, Lake JR, Rogillio RB, Leyva JE, Benson TM, Corriere LS, Handunge BP, Kastin AJ. Tyr-MIF-1 precipitates abstinence syndrome in morphine-dependent rats. Brain Research. 610: 169-71. PMID 8100171 DOI: 10.1016/0006-8993(93)91233-I  1
1993 Hackler L, Kastin AJ, Erchegyi J, Zadina JE. Isolation of Tyr-W-MIF-1 from bovine hypothalami. Neuropeptides. 24: 159-64. PMID 8097302 DOI: 10.1016/0143-4179(93)90080-T  1
1993 Zadina JE, Chang SL, Ge LJ, Kastin AJ. Mu opiate receptor down-regulation by morphine and up-regulation by naloxone in SH-SY5Y human neuroblastoma cells. The Journal of Pharmacology and Experimental Therapeutics. 265: 254-62. PMID 8097244  1
1993 Erchegyi J, Zadina JE, Qiu XD, Kersh DC, Ge LJ, Brown MM, Kastin AJ. Structure-activity relationships of analogs of the endogenous brain peptides Tyr-MIF-1 and Tyr-W-MIF-1. Peptide Research. 6: 31-8. PMID 8094991  1
1993 Harrison LM, Zadina JE, Banks WA, Kastin AJ. Effects of neonatal treatment with Tyr-MIF-1, morphiceptin, and morphine on development, tail flick, and blood-brain barrier transport. Brain Research. Developmental Brain Research. 75: 207-12. PMID 7903224 DOI: 10.1016/0165-3806(93)90025-6  1
1993 Chang SL, Zadina JE, Ren T. Interleukin-1α activates c-fos proto-oncogene in the rat brain Nida Research Monograph Series. 294.  1
1992 Erchegyi J, Kastin AJ, Zadina JE. Isolation of a novel tetrapeptide with opiate and antiopiate activity from human brain cortex: Tyr-Pro-Trp-Gly-NH2 (Tyr-W-MIF-1). Peptides. 13: 623-31. PMID 1359507 DOI: 10.1016/0196-9781(92)90165-Y  1
1992 Erchegyi J, Kastin AJ, Zadina JE, Qiu XD. Isolation of a heptapeptide Val-Val-Tyr-Pro-Trp-Thr-Gln (valorphin) with some opiate activity. International Journal of Peptide and Protein Research. 39: 477-84. PMID 1356941  1
1992 Zadina JE, Kastin AJ, Kersh D, Wyatt A. Tyr-MIF-1 and hemorphin can act as opiate agonists as well as antagonists in the guinea pig ileum. Life Sciences. 51: 869-85. PMID 1355851 DOI: 10.1016/0024-3205(92)90615-V  1
1990 Kastin AJ, Banks WA, Zadina JE. A decade of changing perceptions about neuropeptides. Annals of the New York Academy of Sciences. 579: 1-7. PMID 2186682 DOI: 10.1111/j.1749-6632.1990.tb48348.x  1
1990 Zadina JE, Kastin AJ, Ge LJ, Brantl V. Hemorphins, cytochrophins, and human beta-casomorphins bind to antiopiate (TYR-MIE-1) as well as opiate binding sites in rat brain. Life Sciences. 47: PL25-30. PMID 1976197 DOI: 10.1016/0024-3205(90)90632-2  1
1990 Zadina JE, Kastin AJ, Ge LJ. Tyr-MIF-1 binding in brain is not altered by ligands selective for the GABAA/benzodiazepine receptor. Neuroscience Letters. 110: 143-7. PMID 1970141 DOI: 10.1016/0304-3940(90)90802-G  1
1990 Zadina JE, Chang SL, Ge LJ, Kastin AJ, Harlan RE. Downregulation of mu opiate receptors by morphine and presence of Tyr-MIF-1 binding sites in SH-SY5Y human neuroblastoma cells New Leads in Opioid Research: Proceedings of the International Narcotics Research Conference. Ics914. 151-152.  1
1989 Kostrzewa RM, White TG, Zadina JE, Kastin AJ. MIF-1 attenuates apomorphine stereotypies in adult rats after neonatal 6-hydroxydopamine. European Journal of Pharmacology. 163: 33-42. PMID 2568266 DOI: 10.1016/0014-2999(89)90392-0  1
1989 Zadina JE, Kastin AJ, Ge LJ, Gulden H, Bungart KJ. Chronic, but not acute, administration of morphine alters antiopiate (Tyr-MIF-1) binding sites in rat brain. Life Sciences. 44: 555-61. PMID 2564620 DOI: 10.1016/0024-3205(89)90617-6  1
1987 Kastin AJ, Ehrensing RH, Banks WA, Zadina JE. Possible therapeutic implications of the effects of some peptides on the brain. Progress in Brain Research. 72: 223-34. PMID 3615900  1
1987 Zadina JE, Kastin AJ, Manasco PK, Pignatiello MF, Nastiuk KL. Long-term hyperalgesia induced by neonatal beta-endorphin and morphiceptin is blocked by neonatal Tyr-MIF-1. Brain Research. 409: 10-8. PMID 2884015 DOI: 10.1016/0006-8993(87)90736-0  1
1986 Zadina JE, Banks WA, Kastin AJ. Central nervous system effects of peptides, 1980-1985: a cross-listing of peptides and their central actions from the first six years of the journal Peptides. Peptides. 7: 497-537. PMID 3534808 DOI: 10.1016/0196-9781(86)90020-3  1
1986 Zadina JE, Kastin AJ. Neonatal peptides affect developing rats: beta-endorphin alters nociception and opiate receptors, corticotropin-releasing factor alters corticosterone. Brain Research. 394: 21-9. PMID 3019483  1
1986 Zadina JE, Kastin AJ. Interactions of Tyr-MIF-1 at opiate receptor sites. Pharmacology, Biochemistry, and Behavior. 25: 1303-5. PMID 2880352 DOI: 10.1016/0091-3057(86)90126-7  1
1986 Zadina JE, Kastin AJ. Multi-independent actions of peptides in the brain: LHRH, MIF-1 and CRF Integrative and Comparative Biology. 26: 951-964. DOI: 10.1093/icb/26.4.951  1
1986 Zadina JE, Kastin AJ. Neonatal peptides affect developing rats: β-endorphin alters nociception and opiate receptors, corticotropin-releasing factor alters corticosterone Developmental Brain Research. 29: 21-29. DOI: 10.1016/0165-3806(86)90078-7  1
1985 Zadina JE, Kastin AJ, Coy DH, Adinoff BA. Developmental, behavioral, and opiate receptor changes after prenatal or postnatal beta-endorphin, CRF, or Tyr-MIF-1. Psychoneuroendocrinology. 10: 367-83. PMID 2868478 DOI: 10.1016/0306-4530(85)90078-2  1
1985 Kastin AJ, Stephens E, Zadina JE, Coy DH, Fischman AJ. Tyr-MIF-1, identified in brain tissue, and its analogs are active in two models of antinociception. Pharmacology, Biochemistry, and Behavior. 23: 1045-9. PMID 2867563 DOI: 10.1016/0091-3057(85)90112-1  1
1985 Zadina JE, Kastin AJ. Interactions between the antiopiate Tyr-MIF-1 and the mu opiate morphiceptin at their respective binding sites in brain. Peptides. 6: 965-70. PMID 2867527 DOI: 10.1016/0196-9781(85)90329-8  1
1984 Graf MV, Kastin AJ, Coy DH, Zadina JE. DSIP reduces amphetamine-induced hyperthermia in mice. Physiology & Behavior. 33: 291-5. PMID 6548818 DOI: 10.1016/0031-9384(84)90114-8  1
1984 Zadina JE, Kastin AJ. A rapid filtration method for receptor binding: characterization with mu and delta opiate receptors. Pharmacology, Biochemistry, and Behavior. 21: 947-52. PMID 6097920  1
1984 Kastin AJ, Zadina JE, Banks WA, Graf MV. Misleading concepts in the field of brain peptides. Peptides. 5: 249-53. PMID 6091068 DOI: 10.1016/0196-9781(84)90283-3  1
1983 Kastin AJ, Banks WA, Zadina JE, Graf M. Minireview. Brain peptides: the dangers of constricted nomenclatures. Life Sciences. 32: 295-301. PMID 6402627 DOI: 10.1016/0024-3205(83)90073-5  1
1982 Graf M, Zadina JE, Schoenenberger GA. Amphetamine-induced locomotor behavior of mice is influenced by DSIP. Peptides. 3: 729-31. PMID 6897447 DOI: 10.1016/0196-9781(82)90006-7  1
1982 Zadina JE, Kastin AJ, Krieg EF, Coy DH. Characterization of binding sites for N-Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) in rat brain. Pharmacology, Biochemistry, and Behavior. 17: 1193-8. PMID 6131435 DOI: 10.1016/0091-3057(82)90119-8  1
1981 Zadina JE, Kastin AJ, Fabre LA, Coy DH. Facilitation of sexual receptivity in the rat by an ovulation-inhibiting analog of LHRH. Pharmacology, Biochemistry, and Behavior. 15: 961-4. PMID 7033996 DOI: 10.1016/0091-3057(81)90062-9  1
1981 Luciano MG, Zadina JE, Kastin AJ, Coy DH. Mu and delta opiate receptors in rat brain are affected by GTP but not by MIF-1. Brain Research Bulletin. 7: 677-82. PMID 6120030 DOI: 10.1016/0361-9230(81)90117-9  1
1980 Kastin AJ, Coy DH, Schally AV, Zadina JE. Dissociation of effects of LH-RH analogs on pituitary regulation and reproductive behavior. Pharmacology, Biochemistry, and Behavior. 13: 913-4. PMID 7010384 DOI: 10.1016/0091-3057(80)90228-2  1
1980 Kastin AJ, Zadina JE, Schally AV. Foundations of the clinical use of LHRH: early studies with the porcine hypothalamic hormone. Materia Medica Polona. Polish Journal of Medicine and Pharmacy. 12: 33-6. PMID 6799707  1
1980 Kastin AJ, Nissen C, Zadina JE, Schally AV, Ehrensing RH. Naloxone-like actions of MIF-1 do not require the presence of the pituitary. Pharmacology, Biochemistry, and Behavior. 13: 907-12. PMID 6111087 DOI: 10.1016/0091-3057(80)90227-0  1
1979 Zadina JE, Dunlap JL, Gerall AA. Modifications induced by neonatal steroids in reproductive organs and behavior of male rats. Journal of Comparative and Physiological Psychology. 93: 314-22. PMID 457952  1
1978 Dunlap JL, Zadina JE, Gougis G. Prenatal stress interacts with prepuberal social isolation to reduce male copulatory behavior. Physiology & Behavior. 21: 873-5. PMID 552076 DOI: 10.1016/0031-9384(78)90158-0  1
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