Jennifer J. Linderman - Publications

University of Michigan, Ann Arbor, Ann Arbor, MI 
Receptor mediated cell behavior

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Spinosa PC, Kinnunen PC, Humphries BA, Luker GD, Luker KE, Linderman JJ. Pre-existing Cell States Control Heterogeneity of Both EGFR and CXCR4 Signaling. Cellular and Molecular Bioengineering. 14: 49-64. PMID 33643466 DOI: 10.1007/s12195-020-00640-1  0.68
2021 Joslyn LR, Kirschner DE, Linderman JJ. : A Calibration Protocol That Utilizes Parameter Density Estimation to Explore Parameter Space and Calibrate Complex Biological Models. Cellular and Molecular Bioengineering. 14: 31-47. PMID 33643465 DOI: 10.1007/S12195-020-00650-Z  0.6
2020 Millar JA, Butler JR, Evans S, Mattila JT, Linderman JJ, Flynn JL, Kirschner DE. Spatial Organization and Recruitment of Non-Specific T Cells May Limit T Cell-Macrophage Interactions Within Granulomas. Frontiers in Immunology. 11: 613638. PMID 33552077 DOI: 10.3389/fimmu.2020.613638  0.6
2020 Wessler T, Joslyn LR, Borish HJ, Gideon HP, Flynn JL, Kirschner DE, Linderman JJ. A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination. Plos Computational Biology. 16: e1007280. PMID 32433646 DOI: 10.1371/Journal.Pcbi.1007280  0.6
2020 Cicchese JM, Dartois V, Kirschner DE, Linderman JJ. Both Pharmacokinetic Variability and Granuloma Heterogeneity Impact the Ability of the First-Line Antibiotics to Sterilize Tuberculosis Granulomas. Frontiers in Pharmacology. 11: 333. PMID 32265707 DOI: 10.3389/Fphar.2020.00333  0.6
2019 Renardy M, Hult C, Evans S, Linderman JJ, Kirschner DE. Global sensitivity analysis of biological multi-scale models. Current Opinion in Biomedical Engineering. 11: 109-116. PMID 32864523 DOI: 10.1016/J.Cobme.2019.09.012  0.6
2019 Spinosa PC, Humphries BA, Lewin Mejia D, Buschhaus JM, Linderman JJ, Luker GD, Luker KE. Short-term cellular memory tunes the signaling responses of the chemokine receptor CXCR4. Science Signaling. 12. PMID 31289212 DOI: 10.1126/scisignal.aaw4204  0.68
2019 Sumit M, Jovic A, Neubig RR, Takayama S, Linderman JJ. A Two-Pulse Cellular Stimulation Test Elucidates Variability and Mechanisms in Signaling Pathways. Biophysical Journal. PMID 30782397 DOI: 10.1016/J.Bpj.2019.01.022  1
2018 Marino S, Hult C, Wolberg P, Linderman JJ, Kirschner DE. The Role of Dimensionality in Understanding Granuloma Formation. Computation (Basel, Switzerland). 6. PMID 31258937 DOI: 10.3390/Computation6040058  0.6
2018 Joslyn LR, Pienaar E, DiFazio RM, Suliman S, Kagina BM, Flynn JL, Scriba TJ, Linderman JJ, Kirschner DE. Integrating Non-human Primate, Human, and Mathematical Studies to Determine the Influence of BCG Timing on H56 Vaccine Outcomes. Frontiers in Microbiology. 9: 1734. PMID 30177914 DOI: 10.3389/Fmicb.2018.01734  0.6
2018 Cicchese JM, Evans S, Hult C, Joslyn LR, Wessler T, Millar JA, Marino S, Cilfone NA, Mattila JT, Linderman JJ, Kirschner DE. Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology. Immunological Reviews. 285: 147-167. PMID 30129209 DOI: 10.1111/Imr.12671  0.6
2018 Pienaar E, Linderman JJ, Kirschner DE. Emergence and selection of isoniazid and rifampin resistance in tuberculosis granulomas. Plos One. 13: e0196322. PMID 29746491 DOI: 10.1371/Journal.Pone.0196322  0.6
2017 Warsinske HC, Pienaar E, Linderman JJ, Mattila JT, Kirschner DE. Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma Model. Frontiers in Immunology. 8: 1843. PMID 29326718 DOI: 10.3389/Fimmu.2017.01843  0.6
2017 Cicchese JM, Pienaar E, Kirschner DE, Linderman JJ. Applying optimization algorithms to tuberculosis antibiotic treatment regimens. Cellular and Molecular Bioengineering. 10: 523-535. PMID 29276546 DOI: 10.1007/S12195-017-0507-6  0.6
2017 Spinosa PC, Luker KE, Luker GD, Linderman JJ. The CXCL12/CXCR7 signaling axis, isoforms, circadian rhythms, and tumor cellular composition dictate gradients in tissue. Plos One. 12: e0187357. PMID 29117251 DOI: 10.1371/journal.pone.0187357  0.68
2017 Pienaar E, Sarathy J, Prideaux B, Dietzold J, Dartois V, Kirschner DE, Linderman JJ. Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach. Plos Computational Biology. 13: e1005650. PMID 28817561 DOI: 10.1371/Journal.Pcbi.1005650  0.6
2017 Warsinske HC, DiFazio RM, Linderman JJ, Flynn JL, Kirschner DE. Identifying mechanisms driving formation of granuloma-associated fibrosis during Mycobacterium tuberculosis infection. Journal of Theoretical Biology. PMID 28642013 DOI: 10.1016/J.Jtbi.2017.06.017  0.6
2017 Chang SL, Cavnar SP, Luker KE, Takayama S, Luker GD, Linderman JJ. Correction: Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis. Plos One. 12: e0174189. PMID 28291822 DOI: 10.1371/Journal.Pone.0174189  1
2016 Sumit M, Takayama S, Linderman JJ. New insights into mammalian signaling pathways using microfluidic pulsatile inputs and mathematical modeling. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 27868126 DOI: 10.1039/C6Ib00178E  1
2016 Warsinske HC, Wheaton AK, Kim KK, Linderman JJ, Moore BB, Kirschner DE. Computational Modeling Predicts Simultaneous Targeting of Fibroblasts and Epithelial Cells Is Necessary for Treatment of Pulmonary Fibrosis. Frontiers in Pharmacology. 7: 183. PMID 27445819 DOI: 10.3389/Fphar.2016.00183  1
2016 Marino S, Gideon HP, Gong C, Mankad S, McCrone JT, Lin PL, Linderman JJ, Flynn JL, Kirschner DE. Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome. Plos Computational Biology. 12: e1004804. PMID 27065304 DOI: 10.1371/Journal.Pcbi.1004804  1
2016 Pienaar E, Matern WM, Linderman JJ, Bader JS, Kirschner DE. Multi-scale model of Mycobacterium tuberculosis infection maps metabolite and gene perturbations to granuloma sterilization predictions. Infection and Immunity. PMID 26975995 DOI: 10.1128/Iai.01438-15  1
2015 Linderman JJ, Kirschner DE. In silico models of M. tuberculosis infection provide a route to new therapies. Drug Discovery Today. Disease Models. 15: 37-41. PMID 26904139 DOI: 10.1016/J.Ddmod.2014.02.006  0.6
2015 Ziraldo C, Gong C, Kirschner DE, Linderman JJ. Strategic Priming with Multiple Antigens can Yield Memory Cell Phenotypes Optimized for Infection with Mycobacterium tuberculosis: A Computational Study. Frontiers in Microbiology. 6: 1477. PMID 26779136 DOI: 10.3389/Fmicb.2015.01477  0.6
2015 Pienaar E, Dartois V, Linderman JJ, Kirschner DE. In silico evaluation and exploration of antibiotic tuberculosis treatment regimens. Bmc Systems Biology. 9: 79. PMID 26578235 DOI: 10.1186/S12918-015-0221-8  1
2015 Warsinske HC, Ashley SL, Linderman JJ, Moore BB, Kirschner DE. Identifying Mechanisms of Homeostatic Signaling in Fibroblast Differentiation. Bulletin of Mathematical Biology. PMID 26384829 DOI: 10.1007/S11538-015-0096-2  1
2015 Sumit M, Neubig RR, Takayama S, Linderman JJ. Band-pass processing in a GPCR signaling pathway selects for NFAT transcription factor activation. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 1378-86. PMID 26374065 DOI: 10.1039/C5Ib00181A  1
2015 Cilfone NA, Kirschner DE, Linderman JJ. Strategies for efficient numerical implementation of hybrid multi-scale agent-based models to describe biological systems. Cellular and Molecular Bioengineering. 8: 119-136. PMID 26366228 DOI: 10.1007/S12195-014-0363-6  0.6
2015 Cilfone NA, Pienaar E, Thurber GM, Kirschner DE, Linderman JJ. Systems Pharmacology Approach Toward the Design of Inhaled Formulations of Rifampicin and Isoniazid for Treatment of Tuberculosis. Cpt: Pharmacometrics & Systems Pharmacology. 4: e00022. PMID 26225241 DOI: 10.1002/psp4.22  1
2015 Linderman JJ, Cilfone NA, Pienaar E, Gong C, Kirschner DE. A multi-scale approach to designing therapeutics for tuberculosis. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 591-609. PMID 25924949 DOI: 10.1039/C4Ib00295D  0.6
2015 Chang SL, Cavnar SP, Takayama S, Luker GD, Linderman JJ. Cell, isoform, and environment factors shape gradients and modulate chemotaxis. Plos One. 10: e0123450. PMID 25909600 DOI: 10.1371/Journal.Pone.0123450  1
2015 Gong C, Linderman JJ, Kirschner D. A population model capturing dynamics of tuberculosis granulomas predicts host infection outcomes. Mathematical Biosciences and Engineering : Mbe. 12: 625-42. PMID 25811559 DOI: 10.3934/Mbe.2015.12.625  1
2015 Cilfone NA, Ford CB, Marino S, Mattila JT, Gideon HP, Flynn JL, Kirschner DE, Linderman JJ. Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection. Journal of Immunology (Baltimore, Md. : 1950). 194: 664-77. PMID 25512604 DOI: 10.4049/Jimmunol.1400734  1
2015 Pienaar E, Cilfone NA, Lin PL, Dartois V, Mattila JT, Butler JR, Flynn JL, Kirschner DE, Linderman JJ. A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment. Journal of Theoretical Biology. 367: 166-79. PMID 25497475 DOI: 10.1016/J.Jtbi.2014.11.021  1
2015 Marino S, Cilfone NA, Mattila JT, Linderman JJ, Flynn JL, Kirschner DE. Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection. Infection and Immunity. 83: 324-38. PMID 25368116 DOI: 10.1128/Iai.02494-14  1
2015 Linderman JJ, Cilfone NA, Pienaar E, Gong C, Kirschner DE. A multi-scale approach to designing therapeutics for tuberculosis Integrative Biology (United Kingdom). 7: 591-609. DOI: 10.1039/c4ib00295d  1
2015 Cilfone NA, Kirschner DE, Linderman JJ. Strategies for Efficient Numerical Implementation of Hybrid Multi-scale Agent-Based Models to Describe Biological Systems Cellular and Molecular Bioengineering. 8: 119-136. DOI: 10.1007/s12195-014-0363-6  1
2014 Coggins NL, Trakimas D, Chang SL, Ehrlich A, Ray P, Luker KE, Linderman JJ, Luker GD. CXCR7 controls competition for recruitment of β-arrestin 2 in cells expressing both CXCR4 and CXCR7. Plos One. 9: e98328. PMID 24896823 DOI: 10.1371/Journal.Pone.0098328  1
2014 Zhao S, Chang SL, Linderman JJ, Feng FY, Luker GD. A Comprehensive Analysis of CXCL12 Isoforms in Breast Cancer(1,2.) Translational Oncology. PMID 24836649 DOI: 10.1016/j.tranon.2014.04.001  0.68
2014 Kirschner DE, Hunt CA, Marino S, Fallahi-Sichani M, Linderman JJ. Tuneable resolution as a systems biology approach for multi-scale, multi-compartment computational models. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 6: 289-309. PMID 24810243 DOI: 10.1002/Wsbm.1270  1
2014 Cavnar SP, Ray P, Moudgil P, Chang SL, Luker KE, Linderman JJ, Takayama S, Luker GD. Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 564-76. PMID 24675873 DOI: 10.1039/C4Ib00015C  1
2014 Gong C, Linderman JJ, Kirschner D. Harnessing the heterogeneity of T cell differentiation fate to fine-tune generation of effector and memory T cells. Frontiers in Immunology. 5: 57. PMID 24600448 DOI: 10.3389/Fimmu.2014.00057  1
2014 Linderman JJ, Kirschner DE. In silico models of M. tuberculosis infection provide a route to new therapies Drug Discovery Today: Disease Models. DOI: 10.1016/j.ddmod.2014.02.006  1
2013 Cilfone NA, Perry CR, Kirschner DE, Linderman JJ. Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection. Plos One. 8: e68680. PMID 23869227 DOI: 10.1371/Journal.Pone.0068680  1
2013 Gong C, Mattila JT, Miller M, Flynn JL, Linderman JJ, Kirschner D. Predicting lymph node output efficiency using systems biology. Journal of Theoretical Biology. 335: 169-84. PMID 23816876 DOI: 10.1016/J.Jtbi.2013.06.016  1
2013 Jovic A, Wade SM, Neubig RR, Linderman JJ, Takayama S. Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamics. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 932-9. PMID 23732791 DOI: 10.1039/C3Ib40032H  1
2013 Fallahi-Sichani M, Marino S, Flynn JL, Linderman JJ, Kirschner DE. A systems biology approach for understanding granuloma formation and function in tuberculosis Systems Biology of Tuberculosis. 127-155. DOI: 10.1007/978-1-4614-4966-9_7  1
2013 Porterfield S, Linderman J, Laubach L, Daprano C. Comparison of the effect of caffeine ingestion on time to exhaustion between endurance trained and untrained men Journal of Exercise Physiology Online. 16: 90-98.  0.36
2013 Cilfone NA, Kirschner DE, Linderman JJ. Using an agent-based model of mycobacterium tuberculosis infection to understand the roles of interleukin-10 during disease progression Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 306-307.  1
2012 Fallahi-Sichani M, Kirschner DE, Linderman JJ. NF-κB Signaling Dynamics Play a Key Role in Infection Control in Tuberculosis. Frontiers in Physiology. 3: 170. PMID 22685435 DOI: 10.3389/Fphys.2012.00170  1
2012 Fallahi-Sichani M, Flynn JL, Linderman JJ, Kirschner DE. Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability. Journal of Immunology (Baltimore, Md. : 1950). 188: 3169-78. PMID 22379032 DOI: 10.4049/Jimmunol.1103298  1
2012 Marino S, Fallahi-Sichani M, Linderman JJ, Kirschner DE. Mathematical Models of Anti-TNF Therapies and their Correlation with Tuberculosis Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications. 83-104. DOI: 10.1002/9781118229019.ch5  1
2011 Welliver TP, Chang SL, Linderman JJ, Swanson JA. Ruffles limit diffusion in the plasma membrane during macropinosome formation. Journal of Cell Science. 124: 4106-14. PMID 22194306 DOI: 10.1242/Jcs.091538  1
2011 Mirsky HP, Miller MJ, Linderman JJ, Kirschner DE. Systems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infection. Journal of Theoretical Biology. 287: 160-70. PMID 21798267 DOI: 10.1016/J.Jtbi.2011.06.037  1
2011 Slaney TR, Nie J, Hershey ND, Thwar PK, Linderman J, Burns MA, Kennedy RT. Push-pull perfusion sampling with segmented flow for high temporal and spatial resolution in vivo chemical monitoring. Analytical Chemistry. 83: 5207-13. PMID 21604670 DOI: 10.1021/Ac2003938  1
2011 Jovic A, Wade SM, Miyawaki A, Neubig RR, Linderman JJ, Takayama S. Hi-Fi transmission of periodic signals amid cell-to-cell variability. Molecular Biosystems. 7: 2238-44. PMID 21559542 DOI: 10.1039/C1Mb05031A  1
2011 Fallahi-Sichani M, El-Kebir M, Marino S, Kirschner DE, Linderman JJ. Multiscale computational modeling reveals a critical role for TNF-α receptor 1 dynamics in tuberculosis granuloma formation. Journal of Immunology (Baltimore, Md. : 1950). 186: 3472-83. PMID 21321109 DOI: 10.4049/Jimmunol.1003299  1
2011 Comisar WA, Mooney DJ, Linderman JJ. Integrin organization: linking adhesion ligand nanopatterns with altered cell responses. Journal of Theoretical Biology. 274: 120-30. PMID 21255586 DOI: 10.1016/J.Jtbi.2011.01.007  1
2011 Marino S, Linderman JJ, Kirschner DE. A multifaceted approach to modeling the immune response in tuberculosis. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 479-89. PMID 21197656 DOI: 10.1002/Wsbm.131  1
2010 Jovic A, Howell B, Cote M, Wade SM, Mehta K, Miyawaki A, Neubig RR, Linderman JJ, Takayama S. Phase-locked signals elucidate circuit architecture of an oscillatory pathway. Plos Computational Biology. 6: e1001040. PMID 21203481 DOI: 10.1371/Journal.Pcbi.1001040  1
2010 Fallahi-Sichani M, Schaller MA, Kirschner DE, Kunkel SL, Linderman JJ. Identification of key processes that control tumor necrosis factor availability in a tuberculosis granuloma. Plos Computational Biology. 6: e1000778. PMID 20463877 DOI: 10.1371/Journal.Pcbi.1000778  1
2010 Linderman JJ, Riggs T, Pande M, Miller M, Marino S, Kirschner DE. Characterizing the dynamics of CD4+ T cell priming within a lymph node. Journal of Immunology (Baltimore, Md. : 1950). 184: 2873-85. PMID 20154206 DOI: 10.4049/Jimmunol.0903117  1
2010 Linderman J. 2010 Year in review and farewell: The Editor-in-Chief Journal of Exercise Physiology Online. 13: i-ii.  0.36
2010 Pennington J, Laubach L, De Marco G, Linderman J. Determining the optimal load for maximal power output for the power clean and snatch in collegiate male football players Journal of Exercise Physiology Online. 13: 10-19.  0.36
2009 Mehta K, Hoppe AD, Kainkaryam R, Woolf PJ, Linderman JJ. A computational approach to inferring cellular protein-binding affinities from quantitative fluorescence resonance energy transfer imaging. Proteomics. 9: 5371-83. PMID 19834887 DOI: 10.1002/Pmic.200800494  1
2009 Fallahi-Sichani M, Linderman JJ. Lipid raft-mediated regulation of G-protein coupled receptor signaling by ligands which influence receptor dimerization: a computational study. Plos One. 4: e6604. PMID 19668374 DOI: 10.1371/journal.pone.0006604  1
2009 Mehta K, Mehta G, Takayama S, Linderman J. Quantitative inference of cellular parameters from microfluidic cell culture systems Biotechnology and Bioengineering. 103: 966-974. PMID 19388086 DOI: 10.1002/Bit.22334  1
2009 Mehta G, Lee J, Cha W, Tung YC, Linderman JJ, Takayama S. Hard top soft bottom microfluidic devices for cell culture and chemical analysis. Analytical Chemistry. 81: 3714-22. PMID 19382754 DOI: 10.1021/Ac802178U  1
2009 Kirschner DE, Linderman JJ. Mathematical and computational approaches can complement experimental studies of host-pathogen interactions. Cellular Microbiology. 11: 531-9. PMID 19134115 DOI: 10.1111/J.1462-5822.2008.01281.X  1
2009 Linderman JJ. Modeling of G-protein-coupled receptor signaling pathways. The Journal of Biological Chemistry. 284: 5427-31. PMID 18940812 DOI: 10.1074/jbc.R800028200  1
2009 Laubach L, Porter K, Hovey P, Linderman J. A modest increase in weekly step counts improved cardiovascular function in healthy elderly women Journal of Exercise Physiology Online. 12: 25-32.  0.36
2009 Linderman J. Editorial Journal of Exercise Physiology Online. 12: i-v.  0.36
2008 Brinkerhoff CJ, Traynor JR, Linderman JJ. Collision coupling, crosstalk, and compartmentalization in G-protein coupled receptor systems: can a single model explain disparate results? Journal of Theoretical Biology. 255: 278-86. PMID 18761019 DOI: 10.1016/J.Jtbi.2008.08.003  1
2008 Chang ST, Linderman JJ, Kirschner DE. Effect of multiple genetic polymorphisms on antigen presentation and susceptibility to Mycobacterium tuberculosis infection. Infection and Immunity. 76: 3221-32. PMID 18443099 DOI: 10.1128/Iai.01677-07  1
2008 Brinkerhoff CJ, Choi JS, Linderman JJ. Diffusion-limited reactions in G-protein activation: unexpected consequences of antagonist and agonist competition. Journal of Theoretical Biology. 251: 561-9. PMID 18289560 DOI: 10.1016/J.Jtbi.2008.01.002  1
2008 Clark MJ, Linderman JJ, Traynor JR. Endogenous regulators of G protein signaling differentially modulate full and partial mu-opioid agonists at adenylyl cyclase as predicted by a collision coupling model. Molecular Pharmacology. 73: 1538-48. PMID 18285510 DOI: 10.1124/mol.107.043547  1
2008 Riggs T, Walts A, Perry N, Bickle L, Lynch JN, Myers A, Flynn J, Linderman JJ, Miller MJ, Kirschner DE. A comparison of random vs. chemotaxis-driven contacts of T cells with dendritic cells during repertoire scanning. Journal of Theoretical Biology. 250: 732-51. PMID 18068193 DOI: 10.1016/J.Jtbi.2007.10.015  1
2007 Thwar PK, Linderman JJ, Burns MA. Electrodeless direct current dielectrophoresis using reconfigurable field-shaping oil barriers. Electrophoresis. 28: 4572-81. PMID 18072223 DOI: 10.1002/Elps.200700373  1
2007 Comisar WA, Kazmers NH, Mooney DJ, Linderman JJ. Engineering RGD nanopatterned hydrogels to control preosteoblast behavior: a combined computational and experimental approach. Biomaterials. 28: 4409-17. PMID 17619056 DOI: 10.1016/J.Biomaterials.2007.06.018  1
2007 Thwar PK, Guptaroy B, Zhang M, Gnegy ME, Burns MA, Linderman JJ. Simple transporter trafficking model for amphetamine-induced dopamine efflux. Synapse (New York, N.Y.). 61: 500-14. PMID 17415796 DOI: 10.1002/Syn.20390  1
2007 Kirschner DE, Chang ST, Riggs TW, Perry N, Linderman JJ. Toward a multiscale model of antigen presentation in immunity. Immunological Reviews. 216: 93-118. PMID 17367337 DOI: 10.1111/J.1600-065X.2007.00490.X  1
2007 Kinzer-Ursem TL, Linderman JJ. Both ligand- and cell-specific parameters control ligand agonism in a kinetic model of g protein-coupled receptor signaling. Plos Computational Biology. 3: e6. PMID 17222056 DOI: 10.1371/journal.pcbi.0030006  1
2007 Mehta G, Mehta K, Sud D, Song JW, Bersano-Begey T, Futai N, Heo YS, Mycek MA, Linderman JJ, Takayama S. Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture. Biomedical Microdevices. 9: 123-34. PMID 17160707 DOI: 10.1007/S10544-006-9005-7  1
2007 Mehta G, Kiel MJ, Lee JW, Kotov N, Linderman JJ, Takayama S. Polyelectrolyte-clay-protein layer films on microfluidic PDMS bioreactor surfaces for primary murine bone marrow culture** Advanced Functional Materials. 17: 2701-2709. DOI: 10.1002/Adfm.200700016  1
2006 Sud D, Mehta G, Mehta K, Linderman J, Takayama S, Mycek MA. Optical imaging in microfluidic bioreactors enables oxygen monitoring for continuous cell culture Journal of Biomedical Optics. 11. PMID 17092147 DOI: 10.1117/1.2355665  1
2006 Chang ST, Ghosh D, Kirschner DE, Linderman JJ. Peptide length-based prediction of peptide-MHC class II binding. Bioinformatics (Oxford, England). 22: 2761-7. PMID 17000752 DOI: 10.1093/Bioinformatics/Btl479  1
2006 Mehta K, Linderman JJ. Model-based analysis and design of a microchannel reactor for tissue engineering. Biotechnology and Bioengineering. 94: 596-609. PMID 16586504 DOI: 10.1002/Bit.20857  1
2006 Kinzer-Ursem TL, Sutton KL, Waller A, Omann GM, Linderman JJ. Multiple receptor states are required to describe both kinetic binding and activation of neutrophils via N-formyl peptide receptor ligands. Cellular Signalling. 18: 1732-47. PMID 16530386 DOI: 10.1016/J.Cellsig.2006.01.014  1
2006 Comisar WA, Hsiong SX, Kong HJ, Mooney DJ, Linderman JJ. Multi-scale modeling to predict ligand presentation within RGD nanopatterned hydrogels. Biomaterials. 27: 2322-9. PMID 16316682 DOI: 10.1016/J.Biomaterials.2005.10.037  1
2006 Sud D, Mehta G, Mehta K, Linderman J, Takayama S, Mycek MA. Fluorescence lifetime imaging microscopy (FLIM) measures oxygen gradients in microfluidic bioreactors Optics Infobase Conference Papers. DOI: 10.1364/Bio.2006.Tui52  1
2005 Brinkerhoff CJ, Linderman JJ. Integrin dimerization and ligand organization: key components in integrin clustering for cell adhesion. Tissue Engineering. 11: 865-76. PMID 15998226 DOI: 10.1089/Ten.2005.11.865  1
2005 Chang ST, Linderman JJ, Kirschner DE. Multiple mechanisms allow Mycobacterium tuberculosis to continuously inhibit MHC class II-mediated antigen presentation by macrophages. Proceedings of the National Academy of Sciences of the United States of America. 102: 4530-5. PMID 15767567 DOI: 10.1073/Pnas.0500362102  1
2005 Chang PS, Axelrod D, Omann GM, Linderman JJ. G protein threshold behavior in the human neutrophil oxidant response: measurement of G proteins available for signaling in responding and nonresponding subpopulations. Cellular Signalling. 17: 605-14. PMID 15683735 DOI: 10.1016/J.Cellsig.2004.10.006  1
2005 Mehta K, Mehta G, Takayama S, Linderman JJ. Modeling of cell culture processes in a micro channel reactor Aiche Annual Meeting, Conference Proceedings. 8344.  1
2005 Kinzer-Ursem TL, Linderman JJ. Cell-specific and ligand-specific parameters affect ligand efficacy in a kinetic model of G protein coupled receptor signaling Aiche Annual Meeting, Conference Proceedings. 8299.  1
2005 Thwar PK, Burns MA, Linderman JJ. On-chip generation and manipulation of emulsion droplets for microfluidic single cell assay devices Aiche Annual Meeting, Conference Proceedings. 12672.  1
2004 Lee KY, Alsberg E, Hsiong S, Comisar W, Linderman J, Ziff R, Mooney D. Nanoscale Adhesion Ligand Organization Regulates Osteoblast Proliferation and Differentiation. Nano Letters. 4: 1501-1506. PMID 25067913 DOI: 10.1021/Nl0493592  1
2004 Brinkerhoff CJ, Woolf PJ, Linderman JJ. Monte Carlo simulations of receptor dynamics: insights into cell signaling. Journal of Molecular Histology. 35: 667-77. PMID 15614622 DOI: 10.1007/S10735-004-2663-Y  1
2004 Waller A, Sutton KL, Kinzer-Ursem TL, Absood A, Traynor JR, Linderman JJ, Omann GM. Receptor binding kinetics and cellular responses of six N-formyl peptide agonists in human neutrophils. Biochemistry. 43: 8204-16. PMID 15209517 DOI: 10.1021/Bi035335I  1
2004 Woolf PJ, Linderman JJ. An algebra of dimerization and its implications for G-protein coupled receptor signaling. Journal of Theoretical Biology. 229: 157-68. PMID 15207471 DOI: 10.1016/J.Jtbi.2004.03.012  1
2004 Chang PS, Absood A, Linderman JJ, Omann GM. Magnetic bead isolation of neutrophil plasma membranes and quantification of membrane-associated guanine nucleotide binding proteins. Analytical Biochemistry. 325: 175-84. PMID 14751252 DOI: 10.1016/J.Ab.2003.10.039  1
2003 Woolf PJ, Linderman JJ. Self organization of membrane proteins via dimerization. Biophysical Chemistry. 104: 217-27. PMID 12834840 DOI: 10.1016/S0301-4622(02)00369-1  1
2003 Keil ML, Solomon NL, Lodhi IJ, Stone KC, Jesaitis AJ, Chang PS, Linderman JJ, Omann GM. Priming-induced localization of G(ialpha2) in high density membrane microdomains. Biochemical and Biophysical Research Communications. 301: 862-72. PMID 12589792 DOI: 10.1016/S0006-291X(03)00057-3  1
2003 Shim J, Bersano-Begey TF, Zhu X, Tkaczyk AH, Linderman JJ, Takayama S. Micro- and nanotechnologies for studying cellular function. Current Topics in Medicinal Chemistry. 3: 687-703. PMID 12570859 DOI: 10.2174/1568026033452393  1
2003 Woolf PJ, Linderman JJ. Untangling ligand induced activation and desensitization of G-protein-coupled receptors. Biophysical Journal. 84: 3-13. PMID 12524261 DOI: 10.1016/S0006-3495(03)74828-0  1
2003 Zhong H, Wade SM, Woolf PJ, Linderman JJ, Traynor JR, Neubig RR. A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding. The Journal of Biological Chemistry. 278: 7278-84. PMID 12446706 DOI: 10.1074/Jbc.M208819200  1
2003 Linderman J, Demchak T, Dallas J, Buckworth J. Ultra-endurance cycling: A field study of human performance during a12-hour moutain bike race Journal of Exercise Physiology Online. 6: 14-23.  0.36
2002 Cunningham JJ, Linderman JJ, Mooney DJ. Externally applied cyclic strain regulates localization of focal contact components in cultured smooth muscle cells. Annals of Biomedical Engineering. 30: 927-35. PMID 12398423 DOI: 10.1114/1.1500408  1
2002 Cunningham JJ, Nikolovski J, Linderman JJ, Mooney DJ. Quantification of fibronectin adsorption to silicone-rubber cell culture substrates. Biotechniques. 32: 876, 878, 880 passim. PMID 11962609 DOI: 10.2144/02324Rr05  1
2001 Waller A, Pipkorn D, Sutton KL, Linderman JJ, Omann GM. Validation of flow cytometric competitive binding protocols and characterization of fluorescently labeled ligands. Cytometry. 45: 102-14. PMID 11590622 DOI: 10.1002/1097-0320(20011001)45:2<102::Aid-Cyto1152>3.0.Co;2-Z  1
2001 Woolf PJ, Kenakin TP, Linderman JJ. Uncovering biases in high throughput screens of G-protein coupled receptors. Journal of Theoretical Biology. 208: 403-18. PMID 11222046 DOI: 10.1006/Jtbi.2000.2227  1
2000 Shea LD, Neubig RR, Linderman JJ. Timing is everything the role of kinetics in G protein activation. Life Sciences. 68: 647-58. PMID 11205879 DOI: 10.1016/S0024-3205(00)00977-2  1
2000 Cunningham J, Linderman J, Mooney D. Focal contact composition is altered by mechanical strain applied via the extracellular matrix Annals of Biomedical Engineering. 28: S-91.  1
1999 Riccobene TA, Omann GM, Linderman JJ. Modeling activation and desensitization of G-protein coupled receptors provides insight into ligand efficacy. Journal of Theoretical Biology. 200: 207-22. PMID 10504286 DOI: 10.1006/Jtbi.1999.0988  1
1998 Putnam AJ, Cunningham JJ, Dennis RG, Linderman JJ, Mooney DJ. Microtubule assembly is regulated by externally applied strain in cultured smooth muscle cells. Journal of Cell Science. 111: 3379-87. PMID 9788879  1
1998 Adams JA, Omann GM, Linderman JJ. A mathematical model for ligand/receptor/G-protein dynamics and actin polymerization in human neutrophils. Journal of Theoretical Biology. 193: 543-60. PMID 9745752 DOI: 10.1006/Jtbi.1998.0721  1
1998 Riccobene TA, Waller A, Hoffman JF, Linderman JJ, Omann GM. Threshold and graded response behavior in human neutrophils: effect of varying G-protein or ligand concentrations. Biochemistry. 37: 11534-43. PMID 9708989 DOI: 10.1021/Bi973133E  1
1998 Shea LD, Linderman JJ. Compartmentalization of receptors and enzymes affects activation for a collision coupling mechanism Journal of Theoretical Biology. 191: 249-258. DOI: 10.1006/Jtbi.1997.0571  1
1998 Agresar G, Linderman JJ, Tryggvason G, Powell KG. An Adaptive, Cartesian, Front-Tracking Method for the Motion, Deformation and Adhesion of Circulating Cells Journal of Computational Physics. 143: 346-380. DOI: 10.1006/Jcph.1998.5967  1
1997 Shea LD, Omann GM, Linderman JJ. Calculation of diffusion-limited kinetics for the reactions in collision coupling and receptor cross-linking. Biophysical Journal. 73: 2949-59. PMID 9414209 DOI: 10.1016/S0006-3495(97)78323-1  1
1997 Shea L, Linderman JJ. Mechanistic model of G-protein signal transduction. Determinants of efficacy and effect of precoupled receptors. Biochemical Pharmacology. 53: 519-30. PMID 9105403 DOI: 10.1016/S0006-2952(96)00768-X  1
1996 Agrawal NG, Linderman JJ. Mathematical modeling of helper T lymphocyte/antigen-presenting cell interactions: analysis of methods for modifying antigen processing and presentation. Journal of Theoretical Biology. 182: 487-504. PMID 8944895 DOI: 10.1006/jtbi.1996.0190  1
1996 Hoffman JF, Keil ML, Riccobene TA, Omann GM, Linderman JJ. Interconverting receptor states at 4 degrees C for the neutrophil N-formyl peptide receptor. Biochemistry. 35: 13047-55. PMID 8855940 DOI: 10.1021/Bi961088P  1
1996 Hoffman JF, Linderman JJ, Omann GM. Receptor up-regulation, internalization, and interconverting receptor states. Critical components of a quantitative description of N-formyl peptide-receptor dynamics in the neutrophil. The Journal of Biological Chemistry. 271: 18394-404. PMID 8702483 DOI: 10.1074/Jbc.271.31.18394  1
1995 Agrawal NG, Linderman JJ. Calcium response of helper T lymphocytes to antigen-presenting cells in a single-cell assay. Biophysical Journal. 69: 1178-90. PMID 8519972 DOI: 10.1016/S0006-3495(95)79992-1  1
1995 Mahama PA, Linderman JJ. Monte Carlo simulations of membrane signal transduction events: effect of receptor blockers on G-protein activation. Annals of Biomedical Engineering. 23: 299-307. PMID 7631983 DOI: 10.1007/BF02584430  1
1995 Omann GM, Rengan R, Hoffman JF, Linderman JJ. Rapid oscillations of actin polymerization/depolymerization in polymorphonuclear leukocytes stimulated by leukotriene B4 and platelet-activating factor. Journal of Immunology (Baltimore, Md. : 1950). 155: 5375-81. PMID 7594553  1
1995 Selby DM, Singer DF, Anderson RW, Coligan JE, Linderman JJ, Nairn R. Antigen-presenting cell lines internalize peptide antigens via fluid-phase endocytosis. Cellular Immunology. 163: 47-54. PMID 7538910 DOI: 10.1006/cimm.1995.1097  1
1994 Mahama PA, Linderman JJ. A Monte Carlo study of the dynamics of G-protein activation. Biophysical Journal. 67: 1345-57. PMID 7811949 DOI: 10.1016/S0006-3495(94)80606-X  0.4
1994 Mahama PA, Linderman JJ. Calcium signaling in individual BC3H1 cells: Speed of calcium mobilization and heterogeneity Biotechnology Progress. 10: 45-54. DOI: 10.1021/Bp00025A005  1
1994 Linderman JJ, Mahama PA, Forsten KE, Lauffenburger DA. Diffusion and Probability in Receptor Binding and Signaling Advances in Chemical Engineering. 19: 51-127. DOI: 10.1016/S0065-2377(08)60213-6  1
1992 Mahoney MG, Randall CJ, Linderman JJ, Gross DJ, Slakey LL. Independent pathways regulate the cytosolic [Ca2+] initial transient and subsequent oscillations in individual cultured arterial smooth muscle cells responding to extracellular ATP. Molecular Biology of the Cell. 3: 493-505. PMID 1319242  1
1990 Linderman JJ, Harris LJ, Slakey LL, Gross DJ. Charge-coupled device imaging of rapid calcium transients in cultured arterial smooth muscle cells. Cell Calcium. 11: 131-44. PMID 2354497 DOI: 10.1016/0143-4160(90)90066-4  1
1987 Hammer DA, Linderman JJ, Graves DJ, Lauffenburger DA. Affinity Chromatography for Cell Separation: Mathematical Model and Experimental Analysis Biotechnology Progress. 3: 189-204. DOI: 10.1002/Btpr.5420030310  1
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