Robert O. Blaustein - Publications

Affiliations: 
Merck Research Laboratories, Boston, MA, United States 

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Armstrong PW, Lam CSP, Anstrom KJ, Ezekowitz J, Hernandez AF, O'Connor CM, Pieske B, Ponikowski P, Shah SJ, Solomon SD, Voors AA, She L, Vlajnic V, Carvalho F, Bamber L, ... Blaustein RO, et al. Effect of Vericiguat vs Placebo on Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction: The VITALITY-HFpEF Randomized Clinical Trial. Jama. 324: 1512-1521. PMID 33079152 DOI: 10.1001/jama.2020.15922  0.01
2020 Goren E, Lin LA, Blaustein RO, Ball G. Bayesian Meta-analysis of Safety Outcomes Using Blinded Clinical Trial Data. Therapeutic Innovation & Regulatory Science. PMID 32578177 DOI: 10.1007/s43441-020-00183-7  0.01
2019 Johns DG, Wang SP, Rosa R, Hubert J, Xu S, Chen Y, Bateman T, Blaustein RO. Impact of drug distribution into adipose on tissue function: The cholesteryl ester transfer protein (CETP) inhibitor anacetrapib as a test case. Pharmacology Research & Perspectives. 7: e00543. PMID 31832204 DOI: 10.1002/prp2.543  0.01
2019 Hopewell JC, Ibrahim M, Hill M, Shaw PM, Braunwald E, Blaustein RO, Bowman L, Landray MJ, Sabatine MS, Collins R. Impact of ADCY9 Genotype on Response to Anacetrapib. Circulation. PMID 31331193 DOI: 10.1161/Circulationaha.119.041546  0.01
2019 Butler J, Lam CSP, Anstrom KJ, Ezekowitz J, Hernandez AF, O'Connor CM, Pieske B, Ponikowski P, Shah SJ, Solomon SD, Voors AA, Wu Y, Carvalho F, Bamber L, Blaustein RO, et al. Rationale and Design of the VITALITY-HFpEF Trial. Circulation. Heart Failure. 12: e005998. PMID 31096775 DOI: 10.1161/Circheartfailure.119.005998  0.04
2018 Johns DG, LeVoci L, Krsmanovic M, Lu M, Hartmann G, Xu S, Wang SP, Chen Y, Bateman T, Blaustein RO. Characterization of anacetrapib distribution into the lipid droplet of adipose tissue in mice and human cultured adipocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30567880 DOI: 10.1124/dmd.118.084525  0.01
2017 Fan Q, Maranville JC, Fritsche L, Sim X, Cheung CMG, Chen LJ, Gorski M, Yamashiro K, Ahn J, Laude A, Dorajoo R, Lim TH, Teo YY, Blaustein RO, Yoshimura N, et al. HDL-cholesterol levels and risk of age-related macular degeneration: a multiethnic genetic study using Mendelian randomization. International Journal of Epidemiology. PMID 29025108 DOI: 10.1093/Ije/Dyx189  0.01
2017 Povsic TJ, Scott R, Mahaffey KW, Blaustein R, Edelberg JM, Lefkowitz MP, Solomon SD, Fox JC, Healy KE, Khakoo AY, Losordo DW, Malik FI, Monia BP, Montgomery RL, Riesmeyer J, et al. Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference. Cardiovascular Drugs and Therapy. PMID 28735360 DOI: 10.1007/S10557-017-6739-9  0.01
2017 Bash LD, Weitzman D, Blaustein RO, Sharon O, Shalev V, Chodick G. Comprehensive healthcare resource use among newly diagnosed congestive heart failure. Israel Journal of Health Policy Research. 6: 26. PMID 28593038 DOI: 10.1186/s13584-017-0149-0  0.04
2017 Teramoto T, Daida H, Ikewaki K, Arai H, Maeda Y, Nakagomi M, Shirakawa M, Watanabe Y, Kakikawa T, Numaguchi H, Johnson-Levonas AO, Blaustein RO. Lipid-modifying efficacy and tolerability of anacetrapib added to ongoing statin therapy in Japanese patients with dyslipidemia. Atherosclerosis. 261: 69-77. PMID 28478132 DOI: 10.1016/j.atherosclerosis.2017.03.009  0.01
2017 Krishna R, Gheyas F, Liu Y, Hagen D, Walker B, Chawla A, Cote J, Blaustein RO, Gutstein DE. Chronic Administration of Anacetrapib Is Associated With Accumulation in Adipose and Slow Elimination. Clinical Pharmacology and Therapeutics. PMID 28380664 DOI: 10.1002/cpt.700  0.04
2017 Chodick G, Weitzman D, Blaustein RO, Shalev V, Bash LD. Differences in short and long-term survival between males and females with new-onset heart failure: A retrospective cohort study. European Journal of Internal Medicine. PMID 28336125 DOI: 10.1016/j.ejim.2017.03.010  0.08
2016 Arai H, Teramoto T, Daida H, Ikewaki K, Maeda Y, Nakagomi M, Shirakawa M, Kakikawa T, Numaguchi H, Johnson-Levonas AO, Vaidya S, Blaustein RO. Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib in Japanese patients with heterozygous familial hypercholesterolemia. Atherosclerosis. PMID 27131642 DOI: 10.1016/j.atherosclerosis.2016.03.017  0.01
2014 Webb NJ, Wells TG, Shahinfar S, Massaad R, Dankner WM, Lam C, Santoro EP, McCrary Sisk C, Blaustein RO. A randomized, open-label, dose-response study of losartan in hypertensive children. Clinical Journal of the American Society of Nephrology : Cjasn. 9: 1441-8. PMID 24875194 DOI: 10.2215/CJN.11111113  1
2012 Mruk K, Shandilya SM, Blaustein RO, Schiffer CA, Kobertz WR. Structural insights into neuronal K+ channel-calmodulin complexes. Proceedings of the National Academy of Sciences of the United States of America. 109: 13579-83. PMID 22869708 DOI: 10.1073/Pnas.1207606109  1
2011 Blaustein RO. The anthrax toxin channel: a barrel of LFs. The Journal of General Physiology. 137: 337-41. PMID 21402885 DOI: 10.1085/jgp.201110622  1
2009 Park HJ, Zhang Y, Du C, Welzig CM, Madias C, Aronovitz MJ, Georgescu SP, Naggar I, Wang B, Kim YB, Blaustein RO, Karas RH, Liao R, Mathews CE, Galper JB. Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice. Circulation Research. 105: 287-94. PMID 19423844 DOI: 10.1161/CIRCRESAHA.109.193995  1
2008 Anderson DS, Blaustein RO. Preventing voltage-dependent gating of anthrax toxin channels using engineered disulfides. The Journal of General Physiology. 132: 351-60. PMID 18725530 DOI: 10.1085/jgp.200809984  1
2008 Park HJ, Georgescu SP, Du C, Madias C, Aronovitz MJ, Welzig CM, Wang B, Begley U, Zhang Y, Blaustein RO, Patten RD, Karas RH, Van Tol HH, Osborne TF, Shimano H, et al. Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP. The Journal of Clinical Investigation. 118: 259-71. PMID 18060044 DOI: 10.1172/Jci32011  1
2007 Blaustein RO. On the impossibility of nonzero reversal potentials of passive pores separating symmetric solutions: comment on Haemophilus influenzae outer membrane protein P5 is associated with inorganic polyphosphate and polyhydroxybutyrate. Biophysical Journal. 93: 2978. PMID 17644561 DOI: 10.1529/biophysj.107.104919  1
2006 Darman RB, Ivy AA, Ketty V, Blaustein RO. Constraints on voltage sensor movement in the shaker K+ channel. The Journal of General Physiology. 128: 687-99. PMID 17101817 DOI: 10.1085/jgp.200609624  1
2004 Blaustein RO, Miller C. Ion channels: shake, rattle or roll? Nature. 427: 499-500. PMID 14765181 DOI: 10.1038/427499a  1
2003 Kienker PK, Jakes KS, Blaustein RO, Miller C, Finkelstein A. Sizing the protein translocation pathway of colicin Ia channels. The Journal of General Physiology. 122: 161-76. PMID 12860927 DOI: 10.1085/Jgp.200308852  1
2002 Blaustein RO. Kinetics of tethering quaternary ammonium compounds to K(+) channels. The Journal of General Physiology. 120: 203-16. PMID 12149281 DOI: 10.1085/jgp.20028613  1
2000 Finkelstein A, Oh KJ, Senzel L, Gordon M, Blaustein RO, Collier RJ. The diphtheria toxin channel-forming T-domain translocates its own NH2-terminal region and the catalytic domain across planar phospholipid bilayers. International Journal of Medical Microbiology : Ijmm. 290: 435-40. PMID 11111923 DOI: 10.1016/S1438-4221(00)80059-4  1
2000 Blaustein RO, Cole PA, Williams C, Miller C. Tethered blockers as molecular 'tape measures' for a voltage-gated K+ channel. Nature Structural Biology. 7: 309-11. PMID 10742176 DOI: 10.1038/74076  1
2000 Senzel L, Gordon M, Blaustein RO, Oh KJ, Collier RJ, Finkelstein A. Topography of diphtheria Toxin's T domain in the open channel state. The Journal of General Physiology. 115: 421-34. PMID 10736310 DOI: 10.1085/Jgp.115.4.421  1
1996 Collins JJ, Pins MR, Dinsmore RE, Foster GP, Scully RE, Blaustein RO. A 25-year-old man with hemopericardium, bilateral hemothorax, and hemoptysis after chest trauma New England Journal of Medicine. 334: 452-458. DOI: 10.1056/NEJM199602153340708  1
1990 Blaustein RO, Finkelstein A. Diffusion limitation in the block by symmetric tetraalkylammonium ions of anthrax toxin channels in planar phospholipid bilayer membranes. The Journal of General Physiology. 96: 943-57. PMID 1704047 DOI: 10.1085/Jgp.96.5.943  1
1990 Blaustein RO, Lea EJ, Finkelstein A. Voltage-dependent block of anthrax toxin channels in planar phospholipid bilayer membranes by symmetric tetraalkylammonium ions. Single-channel analysis. The Journal of General Physiology. 96: 921-42. PMID 1704046 DOI: 10.1085/Jgp.96.5.921  1
1990 Blaustein RO, Finkelstein A. Voltage-dependent block of anthrax toxin channels in planar phospholipid bilayer membranes by symmetric tetraalkylammonium ions. Effects on macroscopic conductance. The Journal of General Physiology. 96: 905-19. PMID 1704045 DOI: 10.1085/Jgp.96.5.905  1
1989 Blaustein RO, Koehler TM, Collier RJ, Finkelstein A. Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers. Proceedings of the National Academy of Sciences of the United States of America. 86: 2209-13. PMID 2467303 DOI: 10.1073/Pnas.86.7.2209  1
1988 Blaustein RO, Finkelstein A. A hydroxide ion carrier in planar phospholipid bilayer membranes: (C6F5)2Hg (dipentafluorophenylmercury). Biochimica Et Biophysica Acta. 946: 221-6. PMID 3207739 DOI: 10.1016/0005-2736(88)90396-3  1
1987 Blaustein RO, Germann WJ, Finkelstein A, DasGupta BR. The N-terminal half of the heavy chain of botulinum type A neurotoxin forms channels in planar phospholipid bilayers. Febs Letters. 226: 115-20. PMID 2446925 DOI: 10.1016/0014-5793(87)80562-8  1
1984 Javitch JA, Blaustein RO, Snyder SH. [3H]mazindol binding associated with neuronal dopamine and norepinephrine uptake sites. Molecular Pharmacology. 26: 35-44. PMID 6087116  1
1983 Javitch JA, Blaustein RO, Snyder SH. [3H]mazindol binding associated with neuronal dopamine uptake sites in corpus striatum membranes. European Journal of Pharmacology. 90: 461-2. PMID 6884434 DOI: 10.1016/0014-2999(83)90574-5  1
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