Joel E. Kleinman - Publications

Affiliations: 
CBDB, GCAP, NIMH, DIRP, NIH 
Area:
neuropathology, schizophrenia
Website:
http://cbdb.nimh.nih.gov/

240 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Takahashi Y, Maynard KR, Tippani M, Jaffe AE, Martinowich K, Kleinman JE, Weinberger DR, Hyde TM. Single molecule in situ hybridization reveals distinct localizations of schizophrenia risk-related transcripts SNX19 and AS3MT in human brain. Molecular Psychiatry. PMID 33649454 DOI: 10.1038/s41380-021-01046-9  0.337
2020 Powers B, Joyce C, Kleinman JE, Hyde TM, Ajilore O, Leow A, Sodhi MS. Sex differences in the transcription of glutamate transporters in major depression and suicide. Journal of Affective Disorders. 277: 244-252. PMID 32836031 DOI: 10.1016/J.Jad.2020.07.055  0.539
2020 Tao R, Li C, Jaffe AE, Shin JH, Deep-Soboslay A, Yamin R, Weinberger DR, Hyde TM, Kleinman JE. Cannabinoid receptor CNR1 expression and DNA methylation in human prefrontal cortex, hippocampus and caudate in brain development and schizophrenia. Translational Psychiatry. 10: 158. PMID 32433545 DOI: 10.1038/S41398-020-0832-8  0.382
2020 Jaffe AE, Hoeppner DJ, Saito T, Blanpain L, Ukaigwe J, Burke EE, Collado-Torres L, Tao R, Tajinda K, Maynard KR, Tran MN, Martinowich K, Deep-Soboslay A, Shin JH, Kleinman JE, et al. Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk. Nature Neuroscience. PMID 32203495 DOI: 10.1038/S41593-020-0604-Z  0.312
2019 Collado-Torres L, Burke EE, Peterson A, Shin J, Straub RE, Rajpurohit A, Semick SA, Ulrich WS, Price AJ, Valencia C, Tao R, Deep-Soboslay A, Hyde TM, Kleinman JE, et al. Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia. Neuron. PMID 31174959 DOI: 10.1016/J.Neuron.2019.05.013  0.377
2019 Pergola G, Di Carlo P, Jaffe AE, Papalino M, Chen Q, Hyde TM, Kleinman JE, Shin JH, Rampino A, Blasi G, Weinberger DR, Bertolino A. Prefrontal Coexpression of Schizophrenia Risk Genes Is Associated With Treatment Response in Patients. Biological Psychiatry. PMID 31126695 DOI: 10.1016/J.Biopsych.2019.03.981  0.301
2019 Semick SA, Bharadwaj RA, Collado-Torres L, Tao R, Shin JH, Deep-Soboslay A, Weiss JR, Weinberger DR, Hyde TM, Kleinman JE, Jaffe AE, Mattay VS. Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer's disease. Acta Neuropathologica. PMID 30712078 DOI: 10.1007/S00401-019-01966-5  0.306
2018 Radulescu E, Jaffe AE, Straub RE, Chen Q, Shin JH, Hyde TM, Kleinman JE, Weinberger DR. Identification and prioritization of gene sets associated with schizophrenia risk by co-expression network analysis in human brain. Molecular Psychiatry. PMID 30478419 DOI: 10.1038/S41380-018-0304-1  0.4
2018 Jaffe AE, Straub RE, Shin JH, Tao R, Gao Y, Collado-Torres L, Kam-Thong T, Xi HS, Quan J, Chen Q, Colantuoni C, Ulrich WS, Maher BJ, Deep-Soboslay A, ... ... Kleinman JE, et al. Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis. Nature Neuroscience. 21: 1117-1125. PMID 30050107 DOI: 10.1038/S41593-018-0197-Y  0.329
2017 Tao R, Davis KN, Li C, Shin JH, Gao Y, Jaffe AE, Gondré-Lewis MC, Weinberger DR, Kleinman JE, Hyde TM. GAD1 alternative transcripts and DNA methylation in human prefrontal cortex and hippocampus in brain development, schizophrenia. Molecular Psychiatry. PMID 28485403 DOI: 10.1038/Mp.2017.105  0.375
2016 Paterson C, Wang Y, Hyde TM, Weinberger DR, Kleinman JE, Law AJ. Temporal, Diagnostic, and Tissue-Specific Regulation of NRG3 Isoform Expression in Human Brain Development and Affective Disorders. The American Journal of Psychiatry. appiajp201616060721. PMID 27771971 DOI: 10.1176/Appi.Ajp.2016.16060721  0.308
2016 Jaffe AE, Kleinman JE. Genetic and epigenetic analysis of schizophrenia in blood-a no-brainer? Genome Medicine. 8: 96. PMID 27655387 DOI: 10.1186/S13073-016-0354-4  0.313
2016 García-Bea A, Walker MA, Hyde TM, Kleinman JE, Harrison PJ, Lane TA. Metabotropic glutamate receptor 3 (mGlu3; mGluR3; GRM3) in schizophrenia: Antibody characterisation and a semi-quantitative western blot study. Schizophrenia Research. PMID 27130562 DOI: 10.1016/J.Schres.2016.04.015  0.32
2016 Davis KN, Tao R, Li C, Gao Y, Gondré-Lewis MC, Lipska BK, Shin JH, Xie B, Ye T, Weinberger DR, Kleinman JE, Hyde TM. GAD2 Alternative Transcripts in the Human Prefrontal Cortex, and in Schizophrenia and Affective Disorders. Plos One. 11: e0148558. PMID 26848839 DOI: 10.1371/Journal.Pone.0148558  0.385
2015 Jaffe AE, Gao Y, Deep-Soboslay A, Tao R, Hyde TM, Weinberger DR, Kleinman JE. Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex. Nature Neuroscience. PMID 26619358 DOI: 10.1038/Nn.4181  0.354
2015 Bharadwaj RA, Kleinman JE. Pathologic Implications for Microtubule-Associated Protein 2 in Schizophrenia Primary Auditory Cortex. Biological Psychiatry. 78: 359-60. PMID 26296425 DOI: 10.1016/j.biopsych.2015.07.011  0.303
2015 Gray AL, Hyde TM, Deep-Soboslay A, Kleinman JE, Sodhi MS. Sex differences in glutamate receptor gene expression in major depression and suicide. Molecular Psychiatry. 20: 1139. PMID 26216299 DOI: 10.1038/mp.2015.114  0.504
2015 Jenkins AK, Paterson C, Wang Y, Hyde TM, Kleinman JE, Law AJ. Neurexin 1 (NRXN1) splice isoform expression during human neocortical development and aging. Molecular Psychiatry. PMID 26216298 DOI: 10.1038/Mp.2015.107  0.328
2015 Kunii Y, Zhang W, Xu Q, Hyde TM, McFadden W, Shin JH, Deep-Soboslay A, Ye T, Li C, Kleinman JE, Wang KH, Lipska BK. CHRNA7 and CHRFAM7A mRNAs: Co-Localized and Their Expression Levels Altered in the Postmortem Dorsolateral Prefrontal Cortex in Major Psychiatric Disorders. The American Journal of Psychiatry. appiajp201514080978. PMID 26206074 DOI: 10.1176/Appi.Ajp.2015.14080978  0.423
2015 Gray AL, Hyde TM, Deep-Soboslay A, Kleinman JE, Sodhi MS. Sex differences in glutamate receptor gene expression in major depression and suicide. Molecular Psychiatry. 20: 1057-68. PMID 26169973 DOI: 10.1038/mp.2015.91  0.551
2015 Mighdoll MI, Tao R, Kleinman JE, Hyde TM. Myelin, myelin-related disorders, and psychosis. Schizophrenia Research. 161: 85-93. PMID 25449713 DOI: 10.1016/j.schres.2014.09.040  0.33
2014 Paterson C, Wang Y, Kleinman JE, Law AJ. Effects of schizophrenia risk variation in the NRG1 gene on NRG1-IV splicing during fetal and early postnatal human neocortical development. The American Journal of Psychiatry. 171: 979-89. PMID 24935406 DOI: 10.1176/Appi.Ajp.2014.13111518  0.329
2014 Dickinson D, Straub RE, Trampush JW, Gao Y, Feng N, Xie B, Shin JH, Lim HK, Ursini G, Bigos KL, Kolachana B, Hashimoto R, Takeda M, Baum GL, Rujescu D, ... ... Kleinman JE, et al. Differential effects of common variants in SCN2A on general cognitive ability, brain physiology, and messenger RNA expression in schizophrenia cases and control individuals. Jama Psychiatry. 71: 647-56. PMID 24718902 DOI: 10.1001/Jamapsychiatry.2014.157  0.619
2014 Morita Y, Callicott JH, Testa LR, Mighdoll MI, Dickinson D, Chen Q, Tao R, Lipska BK, Kolachana B, Law AJ, Ye T, Straub RE, Weinberger DR, Kleinman JE, Hyde TM. Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4929-40. PMID 24695712 DOI: 10.1523/Jneurosci.1423-13.2014  0.614
2014 Kaalund SS, Newburn EN, Ye T, Tao R, Li C, Deep-Soboslay A, Herman MM, Hyde TM, Weinberger DR, Lipska BK, Kleinman JE. Contrasting changes in DRD1 and DRD2 splice variant expression in schizophrenia and affective disorders, and associations with SNPs in postmortem brain. Molecular Psychiatry. 19: 1258-66. PMID 24322206 DOI: 10.1038/mp.2013.165  0.308
2014 Kunii Y, Hyde TM, Ye T, Li C, Kolachana B, Dickinson D, Weinberger DR, Kleinman JE, Lipska BK. Revisiting DARPP-32 in postmortem human brain: changes in schizophrenia and bipolar disorder and genetic associations with t-DARPP-32 expression. Molecular Psychiatry. 19: 192-9. PMID 23295814 DOI: 10.1038/mp.2012.174  0.374
2013 Eisenberg DP, Kleinman J, Berman KF. Epistasis and complex neuropsychiatric phenotypes. Psychiatry. 76: 295-7. PMID 23965266 DOI: 10.1521/psyc.2013.76.3.295  0.328
2013 Blasi G, De Virgilio C, Papazacharias A, Taurisano P, Gelao B, Fazio L, Ursini G, Sinibaldi L, Andriola I, Masellis R, Romano R, Rampino A, Di Giorgio A, Lo Bianco L, Caforio G, ... ... Kleinman JE, et al. Converging evidence for the association of functional genetic variation in the serotonin receptor 2a gene with prefrontal function and olanzapine treatment. Jama Psychiatry. 70: 921-30. PMID 23842608 DOI: 10.1001/jamapsychiatry.2013.1378  0.444
2013 Blasi G, Napolitano F, Ursini G, Di Giorgio A, Caforio G, Taurisano P, Fazio L, Gelao B, Attrotto MT, Colagiorgio L, Todarello G, Piva F, Papazacharias A, Masellis R, Mancini M, ... ... Kleinman JE, et al. Association of GSK-3β genetic variation with GSK-3β expression, prefrontal cortical thickness, prefrontal physiology, and schizophrenia. The American Journal of Psychiatry. 170: 868-76. PMID 23598903 DOI: 10.1176/appi.ajp.2012.12070908  0.358
2013 Smith RM, Papp AC, Webb A, Ruble CL, Munsie LM, Nisenbaum LK, Kleinman JE, Lipska BK, Sadee W. Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex. Biological Psychiatry. 73: 546-54. PMID 23158458 DOI: 10.1016/J.Biopsych.2012.09.028  0.337
2013 Kreisl WC, Jenko KJ, Hines CS, Lyoo CH, Corona W, Morse CL, Zoghbi SS, Hyde T, Kleinman JE, Pike VW, McMahon FJ, Innis RB. A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 53-8. PMID 22968319 DOI: 10.1038/jcbfm.2012.131  0.364
2012 Jenko KJ, Hirvonen J, Henter ID, Anderson KB, Zoghbi SS, Hyde TM, Deep-Soboslay A, Innis RB, Kleinman JE. Binding of a tritiated inverse agonist to cannabinoid CB1 receptors is increased in patients with schizophrenia. Schizophrenia Research. 141: 185-8. PMID 22910406 DOI: 10.1016/j.schres.2012.07.021  0.43
2012 Ye T, Lipska BK, Tao R, Hyde TM, Wang L, Li C, Choi KH, Straub RE, Kleinman JE, Weinberger DR. Analysis of copy number variations in brain DNA from patients with schizophrenia and other psychiatric disorders. Biological Psychiatry. 72: 651-4. PMID 22795968 DOI: 10.1016/j.biopsych.2012.06.014  0.397
2012 Law AJ, Wang Y, Sei Y, O'Donnell P, Piantadosi P, Papaleo F, Straub RE, Huang W, Thomas CJ, Vakkalanka R, Besterman AD, Lipska BK, Hyde TM, Harrison PJ, Kleinman JE, et al. Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy. Proceedings of the National Academy of Sciences of the United States of America. 109: 12165-70. PMID 22689948 DOI: 10.1073/Pnas.1206118109  0.452
2012 Zeng H, Shen EH, Hohmann JG, Oh SW, Bernard A, Royall JJ, Glattfelder KJ, Sunkin SM, Morris JA, Guillozet-Bongaarts AL, Smith KA, Ebbert AJ, Swanson B, Kuan L, Page DT, ... ... Kleinman JE, et al. Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures. Cell. 149: 483-96. PMID 22500809 DOI: 10.1016/J.Cell.2012.02.052  0.319
2012 Tao R, Li C, Newburn EN, Ye T, Lipska BK, Herman MM, Weinberger DR, Kleinman JE, Hyde TM. Transcript-specific associations of SLC12A5 (KCC2) in human prefrontal cortex with development, schizophrenia, and affective disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5216-22. PMID 22496567 DOI: 10.1523/JNEUROSCI.4626-11.2012  0.48
2011 Newburn EN, Hyde TM, Ye T, Morita Y, Weinberger DR, Kleinman JE, Lipska BK. Interactions of human truncated DISC1 proteins: implications for schizophrenia. Translational Psychiatry. 1: e30. PMID 22832604 DOI: 10.1038/tp.2011.31  0.399
2011 Colantuoni C, Lipska BK, Ye T, Hyde TM, Tao R, Leek JT, Colantuoni EA, Elkahloun AG, Herman MM, Weinberger DR, Kleinman JE. Temporal dynamics and genetic control of transcription in the human prefrontal cortex. Nature. 478: 519-23. PMID 22031444 DOI: 10.1038/Nature10524  0.34
2011 Kang HJ, Kawasawa YI, Cheng F, Zhu Y, Xu X, Li M, Sousa AM, Pletikos M, Meyer KA, Sedmak G, Guennel T, Shin Y, Johnson MB, Krsnik Z, Mayer S, ... ... Kleinman JE, et al. Spatio-temporal transcriptome of the human brain. Nature. 478: 483-9. PMID 22031440 DOI: 10.1038/Nature10523  0.33
2011 Hyde TM, Lipska BK, Ali T, Mathew SV, Law AJ, Metitiri OE, Straub RE, Ye T, Colantuoni C, Herman MM, Bigelow LB, Weinberger DR, Kleinman JE. Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11088-95. PMID 21795557 DOI: 10.1523/Jneurosci.1234-11.2011  0.437
2011 Zhang F, Chen Q, Ye T, Lipska BK, Straub RE, Vakkalanka R, Rujescu D, St Clair D, Hyde TM, Bigelow L, Kleinman JE, Weinberger DR. Evidence of sex-modulated association of ZNF804A with schizophrenia. Biological Psychiatry. 69: 914-7. PMID 21349497 DOI: 10.1016/j.biopsych.2011.01.003  0.357
2011 Kleinman JE. Genetic variation in PCLO is associated with prefrontal cortex expression and bipolar disorder. Biological Psychiatry. 69: 298. PMID 21272735 DOI: 10.1016/j.biopsych.2010.12.008  0.4
2011 Kleinman JE, Law AJ, Lipska BK, Hyde TM, Ellis JK, Harrison PJ, Weinberger DR. Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains. Biological Psychiatry. 69: 140-5. PMID 21183009 DOI: 10.1016/J.Biopsych.2010.10.032  0.453
2011 Deep-Soboslay A, Benes FM, Haroutunian V, Ellis JK, Kleinman JE, Hyde TM. Psychiatric brain banking: three perspectives on current trends and future directions. Biological Psychiatry. 69: 104-12. PMID 20673875 DOI: 10.1016/J.Biopsych.2010.05.025  0.351
2011 Guillozet-Bongaarts AL, Hyde TM, Dalley R, Henry A, Hawrylycz M, Hohmann J, Jones A, Kuan L, Royall J, Shen E, Swanson B, Wininger M, Zeng H, Kleinman JE. Gene expression patterns in the DLPFC of patients with schizophrenia and controls F1000research. 2. DOI: 10.7490/F1000Research.1694.1  0.31
2011 Harrison PJ, Lewis DA, Kleinman JE. Neuropathology of Schizophrenia Schizophrenia: Third Edition. 372-392. DOI: 10.1383/Psyt.2005.4.10.18  0.357
2010 Bigos KL, Mattay VS, Callicott JH, Straub RE, Vakkalanka R, Kolachana B, Hyde TM, Lipska BK, Kleinman JE, Weinberger DR. Genetic variation in CACNA1C affects brain circuitries related to mental illness. Archives of General Psychiatry. 67: 939-45. PMID 20819988 DOI: 10.1001/archgenpsychiatry.2010.96  0.658
2010 Kao WT, Wang Y, Kleinman JE, Lipska BK, Hyde TM, Weinberger DR, Law AJ. Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain. Proceedings of the National Academy of Sciences of the United States of America. 107: 15619-24. PMID 20713722 DOI: 10.1073/Pnas.1005410107  0.474
2010 Wong J, Hyde TM, Cassano HL, Deep-Soboslay A, Kleinman JE, Weickert CS. Promoter specific alterations of brain-derived neurotrophic factor mRNA in schizophrenia. Neuroscience. 169: 1071-84. PMID 20553817 DOI: 10.1016/j.neuroscience.2010.05.037  0.451
2010 Tost H, Lipska BK, Vakkalanka R, Lemaitre H, Callicott JH, Mattay VS, Kleinman JE, Marenco S, Weinberger DR. No effect of a common allelic variant in the reelin gene on intermediate phenotype measures of brain structure, brain function, and gene expression. Biological Psychiatry. 68: 105-7. PMID 20434133 DOI: 10.1016/j.biopsych.2010.02.023  0.609
2010 Lemaitre H, Mattay VS, Sambataro F, Verchinski B, Straub RE, Callicott JH, Kittappa R, Hyde TM, Lipska BK, Kleinman JE, McKay R, Weinberger DR. Genetic variation in FGF20 modulates hippocampal biology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5992-7. PMID 20427658 DOI: 10.1523/JNEUROSCI.5773-09.2010  0.589
2010 Eastwood SL, Walker M, Hyde TM, Kleinman JE, Harrison PJ. The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brain. Human Molecular Genetics. 19: 2487-96. PMID 20360304 DOI: 10.1093/Hmg/Ddq130  0.447
2009 Nakata K, Lipska BK, Hyde TM, Ye T, Newburn EN, Morita Y, Vakkalanka R, Barenboim M, Sei Y, Weinberger DR, Kleinman JE. DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms. Proceedings of the National Academy of Sciences of the United States of America. 106: 15873-8. PMID 19805229 DOI: 10.1073/Pnas.0903413106  0.43
2009 Bristow GC, Lane TA, Walker M, Chen L, Sei Y, Hyde TM, Kleinman JE, Harrison PJ, Eastwood SL. Expression of kinase interacting with stathmin (KIS, UHMK1) in human brain and lymphoblasts: Effects of schizophrenia and genotype. Brain Research. 1301: 197-206. PMID 19747464 DOI: 10.1016/J.Brainres.2009.08.090  0.491
2009 Nicodemus KK, Law AJ, Luna A, Vakkalanka R, Straub RE, Kleinman JE, Weinberger DR. A 5' promoter region SNP in NRG1 is associated with schizophrenia risk and type III isoform expression. Molecular Psychiatry. 14: 741-3. PMID 19626024 DOI: 10.1038/Mp.2008.150  0.459
2009 Roth TL, Lubin FD, Sodhi M, Kleinman JE. Epigenetic mechanisms in schizophrenia. Biochimica Et Biophysica Acta. 1790: 869-77. PMID 19559755 DOI: 10.1016/J.Bbagen.2009.06.009  0.626
2009 Huffaker SJ, Chen J, Nicodemus KK, Sambataro F, Yang F, Mattay V, Lipska BK, Hyde TM, Song J, Rujescu D, Giegling I, Mayilyan K, Proust MJ, Soghoyan A, Caforio G, ... ... Kleinman JE, et al. A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia. Nature Medicine. 15: 509-18. PMID 19412172 DOI: 10.1038/Nm.1962  0.643
2009 Mann JJ, Arango VA, Avenevoli S, Brent DA, Champagne FA, Clayton P, Currier D, Dougherty DM, Haghighi F, Hodge SE, Kleinman J, Lehner T, McMahon F, Mo?cicki EK, Oquendo MA, et al. Candidate endophenotypes for genetic studies of suicidal behavior. Biological Psychiatry. 65: 556-63. PMID 19201395 DOI: 10.1016/J.Biopsych.2008.11.021  0.301
2008 Deep-Soboslay A, Iglesias B, Hyde TM, Bigelow LB, Imamovic V, Herman MM, Kleinman JE. Evaluation of tissue collection for postmortem studies of bipolar disorder. Bipolar Disorders. 10: 822-8. PMID 19032714 DOI: 10.1111/j.1399-5618.2008.00607.x  0.33
2008 Ghose S, Crook JM, Bartus CL, Sherman TG, Herman MM, Hyde TM, Kleinman JE, Akil M. Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia. The International Journal of Neuroscience. 118: 1609-27. PMID 18853337 DOI: 10.1080/00207450802330702  0.502
2008 Colantuoni C, Hyde TM, Mitkus S, Joseph A, Sartorius L, Aguirre C, Creswell J, Johnson E, Deep-Soboslay A, Herman MM, Lipska BK, Weinberger DR, Kleinman JE. Age-related changes in the expression of schizophrenia susceptibility genes in the human prefrontal cortex. Brain Structure & Function. 213: 255-71. PMID 18470533 DOI: 10.1007/S00429-008-0181-5  0.434
2008 Weickert CS, Miranda-Angulo AL, Wong J, Perlman WR, Ward SE, Radhakrishna V, Straub RE, Weinberger DR, Kleinman JE. Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia. Human Molecular Genetics. 17: 2293-309. PMID 18424448 DOI: 10.1093/Hmg/Ddn130  0.322
2008 Sartorius LJ, Weinberger DR, Hyde TM, Harrison PJ, Kleinman JE, Lipska BK. Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2626-34. PMID 18256595 DOI: 10.1038/Sj.Npp.1301669  0.492
2008 Halim ND, Lipska BK, Hyde TM, Deep-Soboslay A, Saylor EM, Herman MM, Thakar J, Verma A, Kleinman JE. Increased lactate levels and reduced pH in postmortem brains of schizophrenics: medication confounds. Journal of Neuroscience Methods. 169: 208-13. PMID 18177946 DOI: 10.1016/j.jneumeth.2007.11.017  0.448
2008 Mitkus SN, Hyde TM, Vakkalanka R, Kolachana B, Weinberger DR, Kleinman JE, Lipska BK. Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia. Schizophrenia Research. 98: 129-38. PMID 17964117 DOI: 10.1016/j.schres.2007.09.032  0.454
2008 Weickert CS, Rothmond DA, Hyde TM, Kleinman JE, Straub RE. Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients. Schizophrenia Research. 98: 105-10. PMID 17961984 DOI: 10.1016/J.Schres.2007.05.041  0.452
2008 Colantuoni C, Hyde TM, Mitkus S, Joseph A, Sartorius L, Aguirre C, Creswell J, Johnson E, Deep-Soboslay A, Herman MM, Lipska BK, Weinberger DR, Kleinman JE. Age-related changes in the expression of schizophrenia susceptibility genes in the human prefrontal cortex (Brain Structure and Function (2008) DOI: 10.1007/s00429-008-0181-5) Brain Structure and Function. 213: 273. DOI: 10.1007/S00429-008-0188-Y  0.447
2007 Mathew SV, Law AJ, Lipska BK, Dávila-García MI, Zamora ED, Mitkus SN, Vakkalanka R, Straub RE, Weinberger DR, Kleinman JE, Hyde TM. Alpha7 nicotinic acetylcholine receptor mRNA expression and binding in postmortem human brain are associated with genetic variation in neuregulin 1. Human Molecular Genetics. 16: 2921-32. PMID 17884806 DOI: 10.1093/Hmg/Ddm253  0.398
2007 Straub RE, Lipska BK, Egan MF, Goldberg TE, Callicott JH, Mayhew MB, Vakkalanka RK, Kolachana BS, Kleinman JE, Weinberger DR. Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression. Molecular Psychiatry. 12: 854-69. PMID 17767149 DOI: 10.1038/sj.mp.4001988  0.615
2007 Meyer-Lindenberg A, Straub RE, Lipska BK, Verchinski BA, Goldberg T, Callicott JH, Egan MF, Huffaker SS, Mattay VS, Kolachana B, Kleinman JE, Weinberger DR. Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition. The Journal of Clinical Investigation. 117: 672-82. PMID 17290303 DOI: 10.1172/JCI30413  0.638
2007 Law AJ, Kleinman JE, Weinberger DR, Weickert CS. Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia. Human Molecular Genetics. 16: 129-41. PMID 17164265 DOI: 10.1093/Hmg/Ddl449  0.321
2007 Weickert CS, Webster MJ, Gondipalli P, Rothmond D, Fatula RJ, Herman MM, Kleinman JE, Akil M. Postnatal alterations in dopaminergic markers in the human prefrontal cortex. Neuroscience. 144: 1109-19. PMID 17123740 DOI: 10.1016/J.Neuroscience.2006.10.009  0.444
2007 Tunbridge EM, Weickert CS, Kleinman JE, Herman MM, Chen J, Kolachana BS, Harrison PJ, Weinberger DR. Catechol-o-methyltransferase enzyme activity and protein expression in human prefrontal cortex across the postnatal lifespan. Cerebral Cortex (New York, N.Y. : 1991). 17: 1206-12. PMID 16835293 DOI: 10.1093/Cercor/Bhl032  0.328
2006 Weickert C, Straub R, Kleinman J, Hyde T, Rothmond D. Reduced dysbindin (DTNBP1) mRNA in hippocampus of patients with schizophrenia. Acta Neuropsychiatrica. 18: 307-308. PMID 27397329 DOI: 10.1017/S0924270800031719  0.459
2006 Lipska BK, Mitkus SN, Mathew SV, Fatula R, Hyde TM, Weinberger DR, Kleinman JE. Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophrenia. Dialogues in Clinical Neuroscience. 8: 353-7. PMID 17117617  0.382
2006 Lipska BK, Deep-Soboslay A, Weickert CS, Hyde TM, Martin CE, Herman MM, Kleinman JE. Critical factors in gene expression in postmortem human brain: Focus on studies in schizophrenia. Biological Psychiatry. 60: 650-8. PMID 16997002 DOI: 10.1016/J.Biopsych.2006.06.019  0.398
2006 Lipska BK, Mitkus S, Caruso M, Hyde TM, Chen J, Vakkalanka R, Straub RE, Weinberger DR, Kleinman JE. RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity. Human Molecular Genetics. 15: 2804-12. PMID 16905560 DOI: 10.1093/hmg/ddl222  0.321
2006 Webster MJ, Herman MM, Kleinman JE, Shannon Weickert C. BDNF and trkB mRNA expression in the hippocampus and temporal cortex during the human lifespan. Gene Expression Patterns : Gep. 6: 941-51. PMID 16713371 DOI: 10.1016/j.modgep.2006.03.009  0.355
2006 Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R, Harrison PJ, Kleinman JE, Weinberger DR. Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 6747-52. PMID 16618933 DOI: 10.1073/Pnas.0602002103  0.411
2006 Lipska BK, Peters T, Hyde TM, Halim N, Horowitz C, Mitkus S, Weickert CS, Matsumoto M, Sawa A, Straub RE, Vakkalanka R, Herman MM, Weinberger DR, Kleinman JE. Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Human Molecular Genetics. 15: 1245-58. PMID 16510495 DOI: 10.1093/Hmg/Ddl040  0.479
2005 Perlman WR, Tomaskovic-Crook E, Montague DM, Webster MJ, Rubinow DR, Kleinman JE, Weickert CS. Alteration in estrogen receptor alpha mRNA levels in frontal cortex and hippocampus of patients with major mental illness. Biological Psychiatry. 58: 812-24. PMID 16112656 DOI: 10.1016/J.Biopsych.2005.04.047  0.331
2005 Holt DJ, Bachus SE, Hyde TM, Wittie M, Herman MM, Vangel M, Saper CB, Kleinman JE. Reduced density of cholinergic interneurons in the ventral striatum in schizophrenia: an in situ hybridization study. Biological Psychiatry. 58: 408-16. PMID 16023618 DOI: 10.1016/J.Biopsych.2005.04.007  0.712
2005 Perlman WR, Matsumoto M, Beltaifa S, Hyde TM, Saunders RC, Webster MJ, Rubinow DR, Kleinman JE, Weickert CS. Expression of estrogen receptor alpha exon-deleted mRNA variants in the human and non-human primate frontal cortex. Neuroscience. 134: 81-95. PMID 15964702 DOI: 10.1016/J.Neuroscience.2005.03.055  0.366
2005 Weickert CS, Ligons DL, Romanczyk T, Ungaro G, Hyde TM, Herman MM, Weinberger DR, Kleinman JE. Reductions in neurotrophin receptor mRNAs in the prefrontal cortex of patients with schizophrenia. Molecular Psychiatry. 10: 637-50. PMID 15940304 DOI: 10.1038/Sj.Mp.4001678  0.457
2005 Beltaifa S, Webster MJ, Ligons DL, Fatula RJ, Herman MM, Kleinman JE, Weickert CS. Discordant changes in cortical TrkC mRNA and protein during the human lifespan. The European Journal of Neuroscience. 21: 2433-44. PMID 15932601 DOI: 10.1111/J.1460-9568.2005.04074.X  0.352
2005 Matsumoto M, Beltaifa S, Weickert CS, Herman MM, Hyde TM, Saunders RC, Lipska BK, Weinberger DR, Kleinman JE. A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain. Brain Research. Molecular Brain Research. 138: 58-69. PMID 15893849 DOI: 10.1016/J.Molbrainres.2005.04.002  0.342
2005 Webster MJ, O'Grady J, Kleinman JE, Weickert CS. Glial fibrillary acidic protein mRNA levels in the cingulate cortex of individuals with depression, bipolar disorder and schizophrenia. Neuroscience. 133: 453-61. PMID 15885920 DOI: 10.1016/J.Neuroscience.2005.02.037  0.459
2005 Weickert CS, Kittell DA, Saunders RC, Herman MM, Horlick RA, Kleinman JE, Hyde TM. Basic fibroblast growth factor and fibroblast growth factor receptor-1 in the human hippocampal formation. Neuroscience. 131: 219-33. PMID 15680705 DOI: 10.1016/J.Neuroscience.2004.09.070  0.331
2005 Deep-Soboslay A, Akil M, Martin CE, Bigelow LB, Herman MM, Hyde TM, Kleinman JE. Reliability of psychiatric diagnosis in postmortem research. Biological Psychiatry. 57: 96-101. PMID 15607306 DOI: 10.1016/j.biopsych.2004.10.016  0.368
2004 Law AJ, Weickert CS, Hyde TM, Kleinman JE, Harrison PJ. Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines. The American Journal of Psychiatry. 161: 1848-55. PMID 15465982 DOI: 10.1176/Ajp.161.10.1848  0.327
2004 Chen J, Lipska BK, Halim N, Ma QD, Matsumoto M, Melhem S, Kolachana BS, Hyde TM, Herman MM, Apud J, Egan MF, Kleinman JE, Weinberger DR. Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. American Journal of Human Genetics. 75: 807-21. PMID 15457404 DOI: 10.1086/425589  0.387
2004 Egan MF, Straub RE, Goldberg TE, Yakub I, Callicott JH, Hariri AR, Mattay VS, Bertolino A, Hyde TM, Shannon-Weickert C, Akil M, Crook J, Vakkalanka RK, Balkissoon R, Gibbs RA, ... Kleinman JE, et al. Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 101: 12604-9. PMID 15310849 DOI: 10.1073/Pnas.0405077101  0.637
2004 Perlman WR, Weickert CS, Akil M, Kleinman JE. Postmortem investigations of the pathophysiology of schizophrenia: the role of susceptibility genes. Journal of Psychiatry & Neuroscience : Jpn. 29: 287-93. PMID 15309045  0.345
2004 Zhu G, Lipsky RH, Xu K, Ali S, Hyde T, Kleinman J, Akhtar LA, Mash DC, Goldman D. Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5' nuclease assay. Psychopharmacology. 177: 178-84. PMID 15290009 DOI: 10.1007/S00213-004-1938-Z  0.323
2004 Law AJ, Shannon Weickert C, Hyde TM, Kleinman JE, Harrison PJ. Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain. Neuroscience. 127: 125-36. PMID 15219675 DOI: 10.1016/J.Neuroscience.2004.04.026  0.415
2004 Weickert CS, Straub RE, McClintock BW, Matsumoto M, Hashimoto R, Hyde TM, Herman MM, Weinberger DR, Kleinman JE. Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain. Archives of General Psychiatry. 61: 544-55. PMID 15184234 DOI: 10.1001/Archpsyc.61.6.544  0.498
2004 Vawter MP, Shannon Weickert C, Ferran E, Matsumoto M, Overman K, Hyde TM, Weinberger DR, Bunney WE, Kleinman JE. Gene expression of metabolic enzymes and a protease inhibitor in the prefrontal cortex are decreased in schizophrenia. Neurochemical Research. 29: 1245-55. PMID 15176481 DOI: 10.1023/B:Nere.0000023611.99452.47  0.473
2004 Hashimoto R, Straub RE, Weickert CS, Hyde TM, Kleinman JE, Weinberger DR. Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia. Molecular Psychiatry. 9: 299-307. PMID 14569272 DOI: 10.1038/Sj.Mp.4001434  0.466
2004 Ghose S, Weickert CS, Colvin SM, Coyle JT, Herman MM, Hyde TM, Kleinman JE. Glutamate carboxypeptidase II gene expression in the human frontal and temporal lobe in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 117-25. PMID 14560319 DOI: 10.1038/Sj.Npp.1300304  0.458
2003 Law AJ, Weickert CS, Webster MJ, Herman MM, Kleinman JE, Harrison PJ. Changes in NMDA receptor subunit mRNAs and cyclophilin mRNA during development of the human hippocampus. Annals of the New York Academy of Sciences. 1003: 426-30. PMID 14684479 DOI: 10.1196/Annals.1300.043  0.314
2003 Law AJ, Weickert CS, Webster MJ, Herman MM, Kleinman JE, Harrison PJ. Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation. The European Journal of Neuroscience. 18: 1197-205. PMID 12956718 DOI: 10.1046/J.1460-9568.2003.02850.X  0.358
2003 Lehrmann E, Hyde TM, Vawter MP, Becker KG, Kleinman JE, Freed WJ. The use of microarrays to characterize neuropsychiatric disorders: postmortem studies of substance abuse and schizophrenia. Current Molecular Medicine. 3: 437-46. PMID 12942997 DOI: 10.2174/1566524033479690  0.377
2003 Halim ND, Weickert CS, McClintock BW, Hyde TM, Weinberger DR, Kleinman JE, Lipska BK. Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development. Molecular Psychiatry. 8: 797-810. PMID 12931207 DOI: 10.1038/Sj.Mp.4001319  0.415
2003 Weickert CS, Hyde TM, Lipska BK, Herman MM, Weinberger DR, Kleinman JE. Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia. Molecular Psychiatry. 8: 592-610. PMID 12851636 DOI: 10.1038/Sj.Mp.4001308  0.456
2003 Matsumoto M, Weickert CS, Beltaifa S, Kolachana B, Chen J, Hyde TM, Herman MM, Weinberger DR, Kleinman JE. Catechol O-methyltransferase (COMT) mRNA expression in the dorsolateral prefrontal cortex of patients with schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1521-30. PMID 12799619 DOI: 10.1038/Sj.Npp.1300218  0.383
2003 Matsumoto M, Weickert CS, Akil M, Lipska BK, Hyde TM, Herman MM, Kleinman JE, Weinberger DR. Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function. Neuroscience. 116: 127-37. PMID 12535946 DOI: 10.1016/S0306-4522(02)00556-0  0.384
2003 Akil M, Kolachana BS, Rothmond DA, Hyde TM, Weinberger DR, Kleinman JE. Catechol-O-Methyltransferase Genotype and Dopamine Regulation in the Human Brain The Journal of Neuroscience. 23: 2008-2013. DOI: 10.1523/JNEUROSCI.23-06-02008.2003  0.409
2003 Law A, Shannon-Weickert C, Hyde T, Kleinman J, Harrison P. Does synaptic pathology in schizophrenia involve a selective dendritic spine deficit? A study of spinophilin and MAP2 gene expression in the hippocampus Schizophrenia Research. 60: 72-73. DOI: 10.1016/S0920-9964(03)80601-1  0.379
2003 Vawter MP, Weickert CS, Ferran E, Matsuymoto M, Hyde TM, Freed WJ, Kleinman JE, Weinberger DR, Bunney WE. Neuronal gene expression is decreased in prefrontal cortex in schizophrenia Schizophrenia Research. 60: 67. DOI: 10.1016/S0920-9964(03)80585-6  0.451
2003 Shannon-Weickert C, Wyatt JE, Lipska BK, Kleinman JE, Webster MJ. Reduction of GAD-67 MRNA in the striatum of patients with schizophrenia and bipolar disorder Schizophrenia Research. 60: 66. DOI: 10.1016/S0920-9964(03)80583-2  0.445
2002 Webster MJ, Weickert CS, Herman MM, Kleinman JE. BDNF mRNA expression during postnatal development, maturation and aging of the human prefrontal cortex. Brain Research. Developmental Brain Research. 139: 139-50. PMID 12480128 DOI: 10.1016/S0165-3806(02)00540-0  0.364
2002 Vawter MP, Crook JM, Hyde TM, Kleinman JE, Weinberger DR, Becker KG, Freed WJ. Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study. Schizophrenia Research. 58: 11-20. PMID 12363385 DOI: 10.1016/S0920-9964(01)00377-2  0.353
2002 Vawter MP, Thatcher L, Usen N, Hyde TM, Kleinman JE, Freed WJ. Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia. Molecular Psychiatry. 7: 571-8. PMID 12140780 DOI: 10.1038/sj.mp.4001158  0.449
2002 Hamid EH, Hyde TM, Egan MF, Wolf SS, Herman MM, Nemeroff CB, Kleinman JE. Neurotensin receptor binding abnormalities in the entorhinal cortex in schizophrenia and affective disorders. Biological Psychiatry. 51: 795-800. PMID 12007453 DOI: 10.1016/S0006-3223(01)01325-7  0.434
2002 Crook JM, Akil M, Law BC, Hyde TM, Kleinman JE. Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects. Molecular Psychiatry. 7: 157-64. PMID 11840308 DOI: 10.1038/sj.mp.4000966  0.342
2001 Damadzic R, Bigelow LB, Krimer LS, Goldenson DA, Saunders RC, Kleinman JE, Herman MM. A quantitative immunohistochemical study of astrocytes in the entorhinal cortex in schizophrenia, bipolar disorder and major depression: absence of significant astrocytosis. Brain Research Bulletin. 55: 611-8. PMID 11576757 DOI: 10.1016/S0361-9230(01)00529-9  0.407
2001 Webster MJ, Shannon Weickert C, Herman MM, Hyde TM, Kleinman JE. Synaptophysin and GAP-43 mRNA levels in the hippocampus of subjects with schizophrenia. Schizophrenia Research. 49: 89-98. PMID 11343868 DOI: 10.1016/S0920-9964(00)00052-9  0.447
2001 Noga JT, Hyde TM, Bachus SE, Herman MM, Kleinman JE. AMPA receptor binding in the dorsolateral prefrontal cortex of schizophrenics and controls. Schizophrenia Research. 48: 361-3. PMID 11295388 DOI: 10.1016/S0920-9964(00)00121-3  0.708
2001 Weickert CS, Webster MJ, Hyde TM, Herman MM, Bachus SE, Bali G, Weinberger DR, Kleinman JE. Reduced GAP-43 mRNA in dorsolateral prefrontal cortex of patients with schizophrenia. Cerebral Cortex (New York, N.Y. : 1991). 11: 136-47. PMID 11208668 DOI: 10.1093/Cercor/11.2.136  0.77
2000 Vawter MP, Freed WJ, Kleinman JE. Neuropathology of bipolar disorder. Biological Psychiatry. 48: 486-504. PMID 11018222 DOI: 10.1016/S0006-3223(00)00978-1  0.386
2000 Weickert CS, Webster MJ, Colvin SM, Herman MM, Hyde TM, Weinberger DR, Kleinman JE. Localization of epidermal growth factor receptors and putative neuroblasts in human subependymal zone. The Journal of Comparative Neurology. 423: 359-72. PMID 10870078 DOI: 10.1002/1096-9861(20000731)423:3<359::Aid-Cne1>3.0.Co;2-0  0.304
2000 Bachus S, Holt D, Agrawal Y, Hyde T, Herman M, Saper C, Kleinman J. 505. Striatal preprosomatostatin mRNA in schizophrenia Biological Psychiatry. 47: S153. DOI: 10.1016/S0006-3223(00)00775-7  0.733
2000 Crook J, Hyde T, Law B, Shannon Weickert C, Kleinman J. 136. Muscarinic receptor protein and mRNA in DLPFC of schizophrenia and affective disorder Biological Psychiatry. 47: S41. DOI: 10.1016/S0006-3223(00)00398-X  0.332
1999 Holt DJ, Herman MM, Hyde TM, Kleinman JE, Sinton CM, German DC, Hersh LB, Graybiel AM, Saper CB. Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia. Neuroscience. 94: 21-31. PMID 10613493 DOI: 10.1016/S0306-4522(99)00279-1  0.436
1999 Spurney CF, Baca SM, Murray AM, Jaskiw GE, Kleinman JE, Hyde TM. Differential effects of haloperidol and clozapine on ionotropic glutamate receptors in rats. Synapse (New York, N.Y.). 34: 266-76. PMID 10529721 DOI: 10.1002/(SICI)1098-2396(19991215)34:4<266::AID-SYN3>3.0.CO;2-2  0.367
1999 Vawter MP, Howard AL, Hyde TM, Kleinman JE, Freed WJ. Alterations of hippocampal secreted N-CAM in bipolar disorder and synaptophysin in schizophrenia. Molecular Psychiatry. 4: 467-75. PMID 10523820 DOI: 10.1038/Sj.Mp.4000547  0.428
1999 Gurguis GNM, Turkka J, Laruelle M, Kleinman J, Linnoila M. Coupling efficiency of brain β-adrenergic receptors to G(s) protein in suicide, alcoholism and control subjects Psychopharmacology. 145: 31-38. PMID 10445370 DOI: 10.1007/S002130051029  0.329
1999 Helmkamp CE, Bigelow LB, Paltán-Ortiz JD, Torrey EF, Kleinman JE, Herman MM. Evaluation of superior vermal Purkinje cell placement in mental illness. Biological Psychiatry. 45: 1370-5. PMID 10349043 DOI: 10.1016/S0006-3223(98)00153-X  0.376
1998 Vawter MP, Hemperly JJ, Hyde TM, Bachus SE, VanderPutten DM, Howard AL, Cannon-Spoor HE, McCoy MT, Webster MJ, Kleinman JE, Freed WJ. VASE-containing N-CAM isoforms are increased in the hippocampus in bipolar disorder but not schizophrenia. Experimental Neurology. 154: 1-11. PMID 9875262 DOI: 10.1006/Exnr.1998.6889  0.727
1998 Rose AM, Mellett BJ, Valdes R, Kleinman JE, Herman MM, Li R, el-Mallakh RS. Alpha 2 isoform of the Na,K-adenosine triphosphatase is reduced in temporal cortex of bipolar individuals. Biological Psychiatry. 44: 892-7. PMID 9807644 DOI: 10.1016/S0006-3223(97)00440-X  0.344
1998 Weickert CS, Kleinman JE. The neuroanatomy and neurochemistry of schizophrenia. The Psychiatric Clinics of North America. 21: 57-75. PMID 9551491 DOI: 10.1016/S0193-953X(05)70361-0  0.35
1998 Vawter MP, Cannon-Spoor HE, Hemperly JJ, Hyde TM, VanderPutten DM, Kleinman JE, Freed WJ. Abnormal expression of cell recognition molecules in schizophrenia. Experimental Neurology. 149: 424-32. PMID 9500955 DOI: 10.1006/exnr.1997.6721  0.441
1998 Hamid E, Hyde T, Egan M, Bachus S, Kinkead B, Nemeroff C, Wolf S, Herman M, Kleinman J. Abnormalities in neurotensin gene expression levels in the hippocampus of schizophrenics Schizophrenia Research. 29: 102-103. DOI: 10.1016/S0920-9964(97)88560-X  0.677
1998 Bachus S, Hyde T, Rubinstein S, Herman M, Kleinman J. 127. Entorhinal cortical preprosomatostatin mRNA in psychiatric disorders Biological Psychiatry. 43: S38-S39. DOI: 10.1016/S0006-3223(98)90575-3  0.674
1997 Bachus SE, Hyde TM, Akil M, Weickert CS, Vawter MP, Kleinman JE. Neuropathology of suicide. A review and an approach. Annals of the New York Academy of Sciences. 836: 201-19. PMID 9616800 DOI: 10.1111/J.1749-6632.1997.Tb52361.X  0.701
1997 Krimer LS, Herman MM, Saunders RC, Boyd JC, Hyde TM, Carter JM, Kleinman JE, Weinberger DR. A qualitative and quantitative analysis of the entorhinal cortex in schizophrenia. Cerebral Cortex (New York, N.Y. : 1991). 7: 732-9. PMID 9408037 DOI: 10.1093/Cercor/7.8.732  0.448
1997 Hurd YL, Herman MM, Hyde TM, Bigelow LB, Weinberger DR, Kleinman JE. Prodynorphin mRNA expression is increased in the patch vs matrix compartment of the caudate nucleus in suicide subjects. Molecular Psychiatry. 2: 495-500. PMID 9399695 DOI: 10.1038/sj.mp.4000319  0.38
1997 Noga JT, Hyde TM, Herman MM, Spurney CF, Bigelow LB, Weinberger DR, Kleinman JE. Glutamate receptors in the postmortem striatum of schizophrenic, suicide, and control brains. Synapse (New York, N.Y.). 27: 168-76. PMID 9329152 DOI: 10.1002/(SICI)1098-2396(199711)27:3<168::AID-SYN2>3.0.CO;2-B  0.417
1997 Bachus SE, Hyde TM, Herman MM, Egan MF, Kleinman JE. Abnormal cholecystokinin mRNA levels in entorhinal cortex of schizophrenics. Journal of Psychiatric Research. 31: 233-56. PMID 9278188 DOI: 10.1016/S0022-3956(96)00041-6  0.75
1997 Kleinman JE. Advances in the Neurobiology of Schizophrenia. The Journal of Nervous &Amp Mental Disease. 185: 204. DOI: 10.1097/00005053-199703000-00013  0.318
1997 Bachus SE, Hyde TM, Herman MM, Kleinman JE. Effect of chronic neuroleptic exposure on mRNA For The AMPA-A subunit of the AMPA glutamate receptor in postmortem human basal ganglia Schizophrenia Research. 24: 85. DOI: 10.1016/S0920-9964(97)82229-3  0.671
1997 Damadzic R, Goldenson DA, Saunders RC, Krimer LS, Bigelow LB, Herman MM, Kleinman JE. An immunohistochemical study of astrocytes in the entorhinal cortex in schizophrenia: Absence of significant gliosis Schizophrenia Research. 24: 37. DOI: 10.1016/S0920-9964(97)82104-4  0.365
1997 Noga J, Hyde T, Bachus S, Herman M, Weinberger D, Kleinman J. Postmortem glutamate receptor binding in the prefrontal cortex of schizophrenics and controls Schizophrenia Research. 24: 35. DOI: 10.1016/S0920-9964(97)82098-1  0.695
1996 Bachus SE, Kleinman JE. The neuropathology of schizophrenia. The Journal of Clinical Psychiatry. 57: 72-83. PMID 8941174  0.745
1996 Brando LJ, Yolken R, Herman MM, Kleinman JE, Ross CA, Torrey EF. Analysis of the DRPLA triplet repeat in brain tissue and leukocytes from schizophrenics. Psychiatric Genetics. 6: 1-5. PMID 8925251 DOI: 10.1097/00041444-199621000-00001  0.434
1996 Taller AM, Asher DM, Pomeroy KL, Eldadah BA, Godec MS, Falkai PG, Bogert B, Kleinman JE, Stevens JR, Torrey EF. Search for viral nucleic acid sequences in brain tissues of patients with schizophrenia using nested polymerase chain reaction. Archives of General Psychiatry. 53: 32-40. PMID 8540775 DOI: 10.1001/Archpsyc.1996.01830010034006  0.368
1996 Kleinman J. The neuropathology of schizophrenia: Autoradiographic and in situ hybridization studies European Neuropsychopharmacology. 6: 92-93. DOI: 10.1016/0924-977X(96)87727-3  0.325
1996 Bachus S, Hyde T, Herman M, Kleinman J. Elevated cholecystokinin mRNA in dorsolateral prefrontal cortex in suicides Biological Psychiatry. 39: 630. DOI: 10.1016/0006-3223(96)84385-X  0.693
1995 Hitri A, Casanova MF, Kleinman JE, Weinberger DR, Wyatt RJ. Age-related changes in [3H]GBR 12935 binding site density in the prefrontal cortex of controls and schizophrenics. Biological Psychiatry. 37: 175-82. PMID 7727626 DOI: 10.1016/0006-3223(94)00202-E  0.546
1995 Egan MF, Hyde TM, Kleinman JE, Wyatt RJ. Neuroleptic-induced vacuous chewing movements in rodents: incidence and effects of long-term increases in haloperidol dose. Psychopharmacology. 117: 74-81. PMID 7724705 DOI: 10.1007/BF02245101  0.389
1995 Hyde TM, Egan MF, Wing LL, Wyatt RJ, Weinberger DR, Kleinman JE. Persistent catalepsy associated with severe dyskinesias in rats treated with chronic injections of haloperidol decanoate. Psychopharmacology. 118: 142-9. PMID 7617800 DOI: 10.1007/BF02245832  0.416
1995 Tsai G, Passani LA, Slusher BS, Carter R, Baer L, Kleinman JE, Coyle JT. Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Archives of General Psychiatry. 52: 829-36. PMID 7575102 DOI: 10.1001/archpsyc.1995.03950220039008  0.463
1995 Murray A, Hyde T, Knable M, Herman M, Bigelow L, Carter J, Weinberger D, Kleinman J. Distribution of putative D4 dopamine receptors in postmortem striatum from patients with schizophrenia The Journal of Neuroscience. 15: 2186-2191. DOI: 10.1523/JNEUROSCI.15-03-02186.1995  0.375
1995 Bachus S, Hyde T, Herman M, Kleinman J. Limbic cortical serotonin 1A receptor mRNA in schizophrenia Biological Psychiatry. 37: 682-683. DOI: 10.1016/0006-3223(95)94732-C  0.723
1994 Knable MB, Hyde TM, Egan MF, Tosayali M, Wyatt RJ, Kleinman JE. Quantitative autoradiography of striatal dopamine D1, D2 and re-uptake sites in rats with vacuous chewing movements. Brain Research. 646: 217-22. PMID 8069667 DOI: 10.1016/0006-8993(94)90081-7  0.43
1994 Hyde TM, Nawroz S, Goldberg TE, Bigelow LB, Strong D, Ostrem JL, Weinberger DR, Kleinman JE. Is there cognitive decline in schizophrenia? A cross-sectional study. The British Journal of Psychiatry : the Journal of Mental Science. 164: 494-500. PMID 8038938 DOI: 10.1192/BJP.164.4.494  0.387
1994 Hitri A, Casanova MF, Kleinman JE, Wyatt RJ. Fewer dopamine transporter receptors in the prefrontal cortex of cocaine users. The American Journal of Psychiatry. 151: 1074-6. PMID 8010366 DOI: 10.1176/Ajp.151.7.1074  0.359
1994 Hurd YL, Pristupa ZB, Herman MM, Niznik HB, Kleinman JE. The dopamine transporter and dopamine D2 receptor messenger RNAs are differentially expressed in limbic- and motor-related subpopulations of human mesencephalic neurons. Neuroscience. 63: 357-62. PMID 7891851 DOI: 10.1016/0306-4522(94)90535-5  0.357
1994 Lexow N, Joyce JN, Kim SJ, Phillips J, Casanova MF, Bird ED, Kleinman JE, Winokur A. Alterations in TRH receptors in temporal lobe of schizophrenics: a quantitative autoradiographic study. Synapse (New York, N.Y.). 18: 315-27. PMID 7886624 DOI: 10.1002/Syn.890180407  0.408
1994 Egan MF, Hurd Y, Hyde TM, Weinberger DR, Wyatt RJ, Kleinman JE. Alterations in mRNA levels of D2 receptors and neuropeptides in striatonigral and striatopallidal neurons of rats with neuroleptic-induced dyskinesias. Synapse (New York, N.Y.). 18: 178-89. PMID 7531873 DOI: 10.1002/syn.890180303  0.481
1994 Noga J, Hyde T, Herman M, Bigelow L, Weinberger D, Kleinman J. Glutamate receptor autoradiography of postmortem basal ganglia in schizophrenia Biological Psychiatry. 35: 735. DOI: 10.1016/0006-3223(94)91089-8  0.33
1993 Joyce JN, Shane A, Lexow N, Winokur A, Casanova MF, Kleinman JE. Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 8: 315-36. PMID 8512620 DOI: 10.1038/Npp.1993.32  0.306
1993 Karson CN, Casanova MF, Kleinman JE, Griffin WS. Choline acetyltransferase in schizophrenia. The American Journal of Psychiatry. 150: 454-9. PMID 8434662  0.301
1993 Goldberg TE, Greenberg RD, Griffin SJ, Gold JM, Kleinman JE, Pickar D, Schulz SC, Weinberger DR. The effect of clozapine on cognition and psychiatric symptoms in patients with schizophrenia. The British Journal of Psychiatry : the Journal of Mental Science. 162: 43-8. PMID 8425138 DOI: 10.1192/Bjp.162.1.43  0.383
1993 Abi-Dargham A, Laruelle M, Wong DT, Robertson DW, Weinberger DR, Kleinman JE. Pharmacological and regional characterization of [3H]LY278584 binding sites in human brain. Journal of Neurochemistry. 60: 730-7. PMID 8419547 DOI: 10.1111/j.1471-4159.1993.tb03208.x  0.318
1993 Abi-Dargham A, Laruelle M, Lipska B, Jaskiw GE, Wong DT, Robertson DW, Weinberger DR, Kleinman JE. Serotonin 5-HT3 receptors in schizophrenia: a postmortem study of the amygdala. Brain Research. 616: 53-7. PMID 8358629 DOI: 10.1016/0006-8993(93)90191-O  0.343
1993 Laruelle M, Abi-Dargham A, Casanova MF, Toti R, Weinberger DR, Kleinman JE. Selective abnormalities of prefrontal serotonergic receptors in schizophrenia. A postmortem study. Archives of General Psychiatry. 50: 810-8. PMID 8215804 DOI: 10.1001/Archpsyc.1993.01820220066007  0.461
1993 Casanova MF, Carosella NW, Gold JM, Kleinman JE, Weinberger DR, Powers RE. A topographical study of senile plaques and neurofibrillary tangles in the hippocampi of patients with Alzheimer's disease and cognitively impaired patients with schizophrenia. Psychiatry Research. 49: 41-62. PMID 8140181 DOI: 10.1016/0165-1781(93)90029-G  0.325
1993 Ohuoha DC, Hyde TM, Kleinman JE. The role of serotonin in schizophrenia: an overview of the nomenclature, distribution and alterations of serotonin receptors in the central nervous system. Psychopharmacology. 112: S5-15. PMID 7831440 DOI: 10.1007/BF02245003  0.414
1993 Freed WJ, Dillon-Carter O, Kleinman JE. Properties of [3H]AMPA binding in postmortem human brain from psychotic subjects and controls: increases in caudate nucleus associated with suicide. Experimental Neurology. 121: 48-56. PMID 7684336 DOI: 10.1006/exnr.1993.1070  0.33
1993 Goldberg T, Weinberger D, Gold J, Greenberg R, Griffin S, Schulz S, Pickar D, Kleinman J. Neuropsychological specificity and schizophrenia: A comparison with affective groups Schizophrenia Research. 9: 175. DOI: 10.1016/0920-9964(93)90339-K  0.42
1993 Harrison PJ, Lewis DA, Kleinman JE. Neuropathology of Schizophrenia Journal of the Neurological Sciences. 120: 372-392. DOI: 10.1016/0022-510X(93)90008-M  0.323
1992 Egan MF, Hyde TM, Tirschwell DL, Kleinman JE, Weinberger DR. Laterality of appendicular tardive dyskinesia in chronic schizophrenia. Biological Psychiatry. 31: 1098-109. PMID 1525274 DOI: 10.1016/0006-3223(92)90154-R  0.327
1992 Casanova MF, Zito M, Altshuler L, Weinberger DR, Kleinman JE. Normal nucleolar size of entorhinal cortex cells in schizophrenia. Psychiatry Research. 44: 79-82. PMID 1461950 DOI: 10.1016/0165-1781(92)90072-B  0.437
1992 Laruelle M, Jaskiw GE, Lipska BK, Kolachana B, Casanova MF, Kleinman JE, Weinberger DR. D1 and D2 receptor modulation in rat striatum and nucleus accumbens after subchronic and chronic haloperidol treatment. Brain Research. 575: 47-56. PMID 1387032 DOI: 10.1016/0006-8993(92)90421-5  0.302
1992 Alexander RC, Cabirac G, Lowenkopf T, Casanova M, Kleinman J, Wyatt RJ, Kirch DG. Search for evidence of herpes simplex virus, type 1, or varicella-zoster virus infection in postmortem brain tissue from schizophrenic patients. Acta Psychiatrica Scandinavica. 86: 418-20. PMID 1336636 DOI: 10.1111/J.1600-0447.1992.Tb03290.X  0.438
1992 Kleinman JE, Laruelle M, Joyce JN, Casanova MF. Abnormalities of serotonergic neural transmission in prefrontal cortex in schizophrenia. Clinical Neuropharmacology. 15: 397A-398A. PMID 1323396  0.34
1992 Alexander RC, Spector SA, Casanova M, Kleinman J, Wyatt RJ, Kirch DG. Search for cytomegalovirus in the postmortem brains of schizophrenic patients using the polymerase chain reaction. Archives of General Psychiatry. 49: 47-53. PMID 1309417 DOI: 10.1001/Archpsyc.1992.01820010047006  0.532
1991 Casanova MF, Naidu S, Goldberg TE, Moser HW, Khoromi S, Kumar A, Kleinman JE, Weinberger DR. Quantitative magnetic resonance imaging in Rett syndrome. The Journal of Neuropsychiatry and Clinical Neurosciences. 3: 66-72. PMID 7580176 DOI: 10.1176/Jnp.3.1.66  0.325
1991 Daniel DG, Kim E, Kostianovsky D, Goldberg TE, Casanova MF, Pickar D, Kleinman JE, Weinberger DR. Computed tomography measurements of brain density in Schizophrenia. Biological Psychiatry. 29: 745-56. PMID 2054449 DOI: 10.1016/0006-3223(91)90194-Q  0.422
1991 Weinberger DR, Suddath RL, Casanova MF, Torrey EF, Kleinman JE. Crow's 'lateralization hypothesis' for schizophrenia. Archives of General Psychiatry. 48: 85-7. PMID 1984765 DOI: 10.1001/Archpsyc.1991.01810250087013  0.43
1991 Goldberg TE, Bigelow LB, Weinberger DR, Daniel DG, Kleinman JE. Cognitive and behavioral effects of the coadministration of dextroamphetamine and haloperidol in schizophrenia. The American Journal of Psychiatry. 148: 78-84. PMID 1984711 DOI: 10.1176/AJP.148.1.78  0.369
1991 Zigun JR, Daniel DG, Kleinman JE, Weinberger DR, Smith GN, Macewan GW, Ancill RJ, Flaum MA, Arndt S, Andreasen NC. Gender differences in schizophrenia [10] American Journal of Psychiatry. 148: 1754-1756. PMID 1957947  0.316
1991 Hitri A, Venable D, Nguyen HQ, Casanova MF, Kleinman JE, Wyatt RJ. Characteristics of [3H]GBR 12935 binding in the human and rat frontal cortex. Journal of Neurochemistry. 56: 1663-72. PMID 1901595 DOI: 10.1111/J.1471-4159.1991.Tb02065.X  0.38
1991 Weissman AD, Casanova MF, Kleinman JE, London ED, De Souza EB. Selective loss of cerebral cortical sigma, but not PCP binding sites in schizophrenia. Biological Psychiatry. 29: 41-54. PMID 1848113 DOI: 10.1016/0006-3223(91)90209-5  0.33
1991 Laruelle M, Sidhu A, Casanova MF, Weinberger DR, Kleinman JE. Characterization of [125I]SCH 23982 binding in human brain: comparison with [3H]SCH 23390. Neuroscience Letters. 131: 273-6. PMID 1837073 DOI: 10.1016/0304-3940(91)90631-3  0.336
1991 el-Mallakh RS, Kirch DG, Shelton R, Fan KJ, Pezeshkpour G, Kanhouwa S, Wyatt RJ, Kleinman JE. The nucleus basalis of Meynert, senile plaques, and intellectual impairment in schizophrenia. The Journal of Neuropsychiatry and Clinical Neurosciences. 3: 383-6. PMID 1821257 DOI: 10.1176/Jnp.3.4.383  0.535
1991 Iadarola MJ, Ofri D, Kleinman JE. Enkephalin, dynorphin and substance P in postmortem substantia nigra from normals and schizophrenic patients. Life Sciences. 48: 1919-30. PMID 1708847 DOI: 10.1016/0024-3205(91)90224-Y  0.322
1991 Daniel D, Weinberger D, Jones D, Zigun J, Coppola R, Handel S, Bigelow L, Goldberg T, Berman K, Kleinman J. The effect of amphetamine on regional cerebral blood flow during cognitive activation in schizophrenia The Journal of Neuroscience. 11: 1907-1917. DOI: 10.1523/JNEUROSCI.11-07-01907.1991  0.332
1991 Greenberg R, Goldberg T, Griffin S, Gold J, Kleinman J, Pickar D, Weinberger D. Effects of clozapine on cognition in patients with schizophrenia Schizophrenia Research. 4: 385. DOI: 10.1016/0920-9964(91)90322-I  0.398
1991 Hitri A, Casanova M, Kleinman J, Weinberger D, Wyatt R. Age dependent changes in dopamine transporter binding and its relevance to schizophrenia Schizophrenia Research. 4: 346. DOI: 10.1016/0920-9964(91)90259-T  0.449
1990 Altshuler LL, Casanova MF, Goldberg TE, Kleinman JE. The hippocampus and parahippocampus in schizophrenia, suicide, and control brains. Archives of General Psychiatry. 47: 1029-34. PMID 2241505 DOI: 10.1001/Archpsyc.1990.01810230045008  0.428
1990 Casanova MF, Carosella N, Kleinman JE. Neuropathological findings in a suspected case of childhood schizophrenia. The Journal of Neuropsychiatry and Clinical Neurosciences. 2: 313-9. PMID 2136091 DOI: 10.1176/Jnp.2.3.313  0.457
1990 Casanova MF, Stevens JR, Kleinman JE. Astrocytosis in the molecular layer of the dentate gyrus: a study in Alzheimer's disease and schizophrenia. Psychiatry Research. 35: 149-66. PMID 2100806 DOI: 10.1016/0925-4927(90)90017-Z  0.386
1990 Jaskiw GE, Karoum F, Freed WJ, Phillips I, Kleinman JE, Weinberger DR. Effect of ibotenic acid lesions of the medial prefrontal cortex on amphetamine-induced locomotion and regional brain catecholamine concentrations in the rat. Brain Research. 534: 263-72. PMID 2073588 DOI: 10.1016/0006-8993(90)90138-2  0.321
1989 Christison GW, Casanova MF, Weinberger DR, Rawlings R, Kleinman JE. A quantitative investigation of hippocampal pyramidal cell size, shape, and variability of orientation in schizophrenia. Archives of General Psychiatry. 46: 1027-32. PMID 2818140 DOI: 10.1001/Archpsyc.1989.01810110069010  0.304
1989 Casanova MF, Zito M, Bigelow LB, Berthot B, Sanders RD, Kleinman JE. Axonal counts of the corpus callosum of schizophrenic patients. The Journal of Neuropsychiatry and Clinical Neurosciences. 1: 391-3. PMID 2521088 DOI: 10.1176/Jnp.1.4.391  0.348
1989 Daniel D, Kostianovsky D, Kim E, Goldberg T, Casanova M, Kleinman J, Weinberger D. Brain density in schizophrenia Schizophrenia Research. 2: 135. DOI: 10.1016/0920-9964(89)90171-0  0.428
1988 Korpi ER, Kleinman JE, Wyatt RJ. GABA concentrations in forebrain areas of suicide victims. Biological Psychiatry. 23: 109-14. PMID 3334879 DOI: 10.1016/0006-3223(88)90079-0  0.404
1988 Goldberg TE, Kleinman JE, Daniel DG, Myslobodsky MS, Ragland JD, Weinberger DR. Dementia praecox revisited. Age disorientation, mental status, and ventricular enlargement. The British Journal of Psychiatry : the Journal of Mental Science. 153: 187-90. PMID 3267141 DOI: 10.1192/Bjp.153.2.187  0.307
1988 Kaufmann CA, Weinberger DR, Stevens JR, Asher DM, Kleinman JE, Sulima MP, Gibbs CJ, Gajdusek DC. Intracerebral inoculation of experimental animals with brain tissue from patients with schizophrenia. Failure to observe consistent or specific behavioral and neuropathological effects. Archives of General Psychiatry. 45: 648-52. PMID 3132907 DOI: 10.1001/ARCHPSYC.1988.01800310056007  0.405
1988 Kleinman JE, Casanova MF, Jaskiw GE. The neuropathology of schizophrenia. Schizophrenia Bulletin. 14: 209-16. PMID 3059468 DOI: 10.1093/Schbul/14.2.209  0.466
1987 Korpi ER, Kleinman JE, Goodman SI, Wyatt RJ. Neurotransmitter amino acids in post-mortem brains of chronic schizophrenic patients. Psychiatry Research. 22: 291-301. PMID 2893404 DOI: 10.1016/0165-1781(87)90108-9  0.409
1987 Rothman RB, Bykov V, Cadet JL, Kleinman JE. A postmortem study of the effect of chronic opiate abuse on psychotomimetic binding sites of human frontal cortex. Neuropeptides. 10: 261-4. PMID 2825064 DOI: 10.1016/0143-4179(87)90076-X  0.3
1987 Korpi ER, Goodman SI, Kleinman JE, Wyatt RJ. Relationship between tryptophan and serotonin concentrations in postmortem human brain. Medical Biology. 65: 217-20. PMID 2449590  0.345
1986 Kafka MS, Kleinman JE, Karson CN, Wyatt RJ. Alpha-adrenergic receptors and cyclic AMP production in a group of schizophrenic patients. The Hillside Journal of Clinical Psychiatry. 8: 15-24. PMID 3017834  0.345
1986 Korpi ER, Kleinman JE, Goodman SI, Phillips I, DeLisi LE, Linnoila M, Wyatt RJ. Serotonin and 5-hydroxyindoleacetic acid in brains of suicide victims. Comparison in chronic schizophrenic patients with suicide as cause of death. Archives of General Psychiatry. 43: 594-600. PMID 2423050 DOI: 10.1001/Archpsyc.1986.01800060088011  0.481
1986 Bracha HS, Kleinman JE. Postmortem neurochemistry in schizophrenia. The Psychiatric Clinics of North America. 9: 133-41. PMID 2421270 DOI: 10.1016/S0193-953X(18)30639-7  0.432
1985 Bridge TP, Kleinman JE, Karoum F, Wyatt RJ. Postmortem central catecholamines and antemortem cognitive impairment in elderly schizophrenics and controls. Neuropsychobiology. 14: 57-61. PMID 4088459 DOI: 10.1159/000118205  0.449
1985 Kleinman JE, Hong J, Iadarola M, Govoni S, Gillin CJ. Neuropeptides in human brain--postmortem studies. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 9: 91-5. PMID 2581284 DOI: 10.1016/0278-5846(85)90183-6  0.361
1985 Bridge P, Kleinman JE, Karoum F, Wyatt RJ, Bellodi L, Smeraldi E, Orsini A, Cazzullo CL, Wilson WH, Ban TA, Guy W, Jansen AAI, Gier JJd, Slangen JL, Yamadera H, et al. Editorial: Biological Psychiatry/Pharmacopsychiatry Neuropsychobiology. 14: 54-54. DOI: 10.1159/000118202  0.305
1984 Kaufmann CA, Gillin JC, Hill B, O'Laughlin T, Phillips I, Kleinman JE, Wyatt RJ. Muscarinic binding in suicides. Psychiatry Research. 12: 47-55. PMID 6589659 DOI: 10.1016/0165-1781(84)90137-9  0.411
1984 Korpi ER, Kleinman JE, Costakos DT, Linnoila M, Wyatt RJ. Reduced haloperidol in the post-mortem brains of haloperidol-treated patients. Psychiatry Research. 11: 259-69. PMID 6587418 DOI: 10.1016/0165-1781(84)90074-X  0.419
1984 Bracha HS, Kleinman JE. Postmortem studies in psychiatry. The Psychiatric Clinics of North America. 7: 473-85. PMID 6384958 DOI: 10.1016/S0193-953X(18)30745-7  0.314
1984 Kleinman JE, Karson CN, Weinberger DR, Freed WJ, Berman KF, Wyatt RJ. Eye-blinking and cerebral ventricular size in chronic schizophrenic patients. The American Journal of Psychiatry. 141: 1430-2. PMID 6149700 DOI: 10.1176/Ajp.141.11.1430  0.501
1983 Karson CN, Kleinman JE, Berman KF, Phelps BH, Wise CD, DeLisi LE, Jeste DV. An inverse correlation between spontaneous eye-blink rate and platelet monoamine oxidase activity. The British Journal of Psychiatry : the Journal of Mental Science. 142: 43-6. PMID 6831128 DOI: 10.1192/BJP.142.1.43  0.308
1983 Jeste DV, Zalcman S, Weinberger DR, Cutler NR, Bigelow LB, Kleinman JE, Rogol A, Wyatt RJ. Apomorphine response and subtyping of schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 7: 83-8. PMID 6682989 DOI: 10.1016/0278-5846(83)90092-1  0.392
1983 Memo M, Kleinman JE, Hanbauer I. Coupling of dopamine D1 recognition sites with adenylate cyclase in nuclei accumbens and caudatus of schizophrenics. Science (New York, N.Y.). 221: 1304-7. PMID 6310753 DOI: 10.1126/Science.6310753  0.317
1982 Karson CN, Bigelow LB, Kleinman JE, Weinberger DR, Wyatt RJ. Haloperidol-induced changes in blink rates correlate with changes in BPRS score. The British Journal of Psychiatry : the Journal of Mental Science. 140: 503-7. PMID 7104533 DOI: 10.1192/Bjp.140.5.503  0.451
1982 Kleinman JE, Weinberger DR, Rogol AD, Bigelow LB, Klein ST, Gillin JC, Wyatt RJ. Plasma prolactin concentrations and psychopathology in chronic schizophrenia. Archives of General Psychiatry. 39: 655-7. PMID 6979991 DOI: 10.1001/Archpsyc.1982.04290060017004  0.476
1982 DeLisi LE, Freed WJ, Gillin JC, Kleinman JE, Bigelow LB, Wyatt RJ. P-chlorophenylalanine trials in schizophrenic patients. Biological Psychiatry. 17: 471-7. PMID 6211196  0.345
1982 Kleinman JE, Weinberger DR, Rogol A, Shiling DJ, Mendelson WB, Davis GC, Bunney WE, Wyatt RJ. Naloxone in chronic schizophrenic patients: neuroendocrine and behavioral effects. Psychiatry Research. 7: 1-7. PMID 6127744 DOI: 10.1016/0165-1781(82)90047-6  0.365
1981 Wyatt RJ, Karoum F, Stoff DM, Kleinman JE, Gillin JC, Jeste DV, Potkin SG. Monoamine oxidase, phenylethylamine, norepinephrine and schizophrenia. Clinical Genetics. 19: 437-42. PMID 7296934 DOI: 10.1111/j.1399-0004.1981.tb00741.x  0.494
1981 Freed WJ, Karson CN, Kleinman JE, Wyatt RJ. Increased spontaneous eye-blinks cerebellectomized rats. Biological Psychiatry. 16: 789-92. PMID 7284511  0.345
1981 Potkin SG, Weinberger D, Kleinman J, Nasrallah H, Luchins D, Bigelow L, Linnoila M, Fischer SH, Bjornsson TD, Carman J, Gillin JC, Wyatt RJ. Wheat gluten challenge in schizophrenic patients. The American Journal of Psychiatry. 138: 1208-11. PMID 7270725 DOI: 10.1176/AJP.138.9.1208  0.404
1981 Karson CN, Staub RA, Kleinman JE, Wyatt RJ. Drug effect on blink rates in rhesus monkeys: preliminary studies. Biological Psychiatry. 16: 249-54. PMID 7225488  0.345
1981 Karson CN, Staub RA, Kleinman JE, Wyatt RJ. Blink rates and receptor supersensitivity. Neuropharmacology. 20: 91-3. PMID 7219685 DOI: 10.1016/0028-3908(81)90049-6  0.322
1981 Wyatt RJ, Potkin SG, Kleinman JE, Weinberger DR, Luchins DJ, Jeste DV. The schizophrenia syndrome. Examples of biological tools for subclassification. The Journal of Nervous and Mental Disease. 169: 100-12. PMID 7009783 DOI: 10.1097/00005053-198102000-00005  0.545
1981 Karson CN, Berman KF, Donnelly EF, Mendelson WB, Kleinman JE, Wyatt RJ. Speaking, thinking, and blinking. Psychiatry Research. 5: 243-6. PMID 6948307 DOI: 10.1016/0165-1781(81)90070-6  0.301
1981 Aulakh GS, Kleinman JE, Aulakh HS, Albrecht P, Torrey EF, Wyatt RJ. Search for cytomegalovirus in schizophrenic brain tissue. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 167: 172-4. PMID 6262834 DOI: 10.3181/00379727-167-41144  0.446
1981 Karson C, Freed WJ, Kleinman JE, Bigelow LB, Wyatt RJ. Neuroleptics decrease blinking in schizophrenic subjects. Biological Psychiatry. 16: 679-82. PMID 6115684  0.345
1980 Freed WJ, Kleinman JE, Karson CN, Potkin SG, Murphy DL, Wyatt RJ. Eye-blink rates and platelet monoamine oxidase activity in chronic schizophrenic patients. Biological Psychiatry. 15: 329-32. PMID 7417620  0.345
1980 Weinberger DR, Kleinman JE, Luchins DJ, Bigelow LB, Wyatt RJ. Cerebellar pathology in schizophrenia: a controlled postmortem study. The American Journal of Psychiatry. 137: 359-61. PMID 7356066 DOI: 10.1176/AJP.137.3.359  0.532
1980 Nasrallah HA, Kleinman JE, Weinberger DR, Gillin JC, Wyatt RJ. Cerebral ventricular enlargement and dopamine synthesis inhibition in chronic schizophrenia. Archives of General Psychiatry. 37: 1427-. PMID 6108752 DOI: 10.1001/Archpsyc.1980.01780250113018  0.539
1980 Luchins DJ, Weinberger DR, Kleinman JE, Neckers L, Rosenblatt JE, Bigelow LB, Wyatt RJ. Human leukocyte antigen A2 and psychopathology in chronic schizophrenia. The American Journal of Psychiatry. 137: 499-500. PMID 6102440 DOI: 10.1176/AJP.137.4.499  0.51
1980 Weinberger DR, Bigelow LB, Kleinman JE, Klein ST, Rosenblatt JE, Wyatt RJ. Cerebral ventricular enlargement in chronic schizophrenia. An association with poor response to treatment. Archives of General Psychiatry. 37: 11-3. PMID 6101534 DOI: 10.1001/Archpsyc.1980.01780140013001  0.519
1979 Kleinman JE, Potkin S, Rogol A, Buchsbaum MS, Murphy DL, Gillin JC, Nasrallah HA, Wyatt RJ. A correlation between platelet monoamine oxidase activity and plasma prolactin concentrations in man. Science (New York, N.Y.). 206: 479-81. PMID 504993 DOI: 10.1126/Science.504993  0.453
1978 Carman JS, Gillin JC, Murphy DL, Weinberger DR, Kleinman JE, Bigelow LB, Wyatt RJ. Effects of a selective inhibitor of type A monoamine oxidase--Lilly 51641--on behavior, sleep and circadian rhythms in depressed and schizophrenic patients. Communications in Psychopharmacology. 2: 513-23. PMID 371909  0.345
1977 Davis GC, Bunney WE, DeFraites EG, Kleinman JE, van Kammen DP, Post RM, Wyatt RJ. Intravenous naloxone administration in schizophrenia and affective illness. Science (New York, N.Y.). 197: 74-7. PMID 325650 DOI: 10.1126/SCIENCE.325650  0.501
1977 Kleinman JE, Gillin JC, Wyatt RJ. A comparison of the phenomenology of hallucinogens and schizophrenia from some autobiographical accounts. Schizophrenia Bulletin. 3: 560-86. PMID 271353 DOI: 10.1093/Schbul/3.4.560  0.469
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