Viorela Pop - Related publications

Pediatrics Loma Linda University, Loma Linda, United States 
traumatic brain injury
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Chiasseu M, Fesharaki A, Saito T, Saido TC, Strittmatter SM. Gene-environment interaction promotes Alzheimer's risk as revealed by synergy of repeated mild traumatic brain injury and mouse App knock-in. Neurobiology of Disease. 145: 105059. PMID 32858147 DOI: 10.1016/j.nbd.2020.105059   
2020 Irimia A, Maher AS, Chaudhari NN, Chowdhury NF, Jacobs EB, . Acute cognitive deficits after traumatic brain injury predict Alzheimer's disease-like degradation of the human default mode network. Geroscience. PMID 32743786 DOI: 10.1007/s11357-020-00245-6   
2020 Vemula PK, Jing Y, Cicolini J, Zhang H, Mockett BG, Abraham WC, Liu P. Altered brain arginine metabolism with age in the APP/PSEN1 mouse model of Alzheimer's disease. Neurochemistry International. 104798. PMID 32711019 DOI: 10.1016/j.neuint.2020.104798   
2020 Mori T, Koyama N, Yokoo T, Segawa T, Maeda M, Sawmiller D, Tan J, Town T. Gallic Acid is a Dual α/β-Secretase Modulator that Reverses Cognitive Impairment and Remediates Pathology in Alzheimer Mice. The Journal of Biological Chemistry. PMID 32913125 DOI: 10.1074/jbc.RA119.012330   
2020 Jepsen WM, De Both M, Siniard AL, Ramsey K, Piras IS, Naymik M, Henderson A, Huentelman MJ. Adenosine triphosphate Binding Cassette subfamily C member 1 (ABCC1) overexpression reduces APP processing and increases alpha- versus beta-secretase activity, . Biology Open. PMID 32878879 DOI: 10.1242/bio.054627   
2020 Chakraborty S, ThimmaReddygari J, Selvaraj D. G-lymphatic, vascular and immune pathways for Aβ clearance cascade and therapeutic targets for Alzheimer's disease. Combinatorial Chemistry & High Throughput Screening. PMID 32875981 DOI: 10.2174/1386207323666200901095003   
2020 Noe CR, Noe-Letschnig M, Handschuh P, Noe CA, Lanzenberger R. Dysfunction of the Blood-Brain Barrier-A Key Step in Neurodegeneration and Dementia. Frontiers in Aging Neuroscience. 12: 185. PMID 32848697 DOI: 10.3389/fnagi.2020.00185   
2020 Pérez-González R, Kim Y, Miller C, Pacheco-Quinto J, Eckman EA, Levy E. Extracellular vesicles: where the amyloid precursor protein carboxyl-terminal fragments accumulate and amyloid-β oligomerizes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32772431 DOI: 10.1096/fj.202000823R   
2020 Xu Y, Wang C, Wey HY, Liang Y, Chen Z, Choi SH, Ran C, Rynearson KD, Bernales DR, Koegel RE, Fiedler SA, Striar R, Wagner SL, Tanzi RE, Zhang C. Molecular imaging of Alzheimer's disease-related gamma-secretase in mice and nonhuman primates. The Journal of Experimental Medicine. 217. PMID 32936886 DOI: 10.1084/jem.20182266   
2020 Mishra J, Kumar B, Pandey M, Pottoo FH, Fayaz F, Khan FA, Sahoo PK. Carbon Nano Tubes: Novel drug delivery system in amelioration of Alzheimer's disease. Combinatorial Chemistry & High Throughput Screening. PMID 32957874 DOI: 10.2174/1386207323999200918112538   
2020 Ewers M, Biechele G, Suárez-Calvet M, Sacher C, Blume T, Morenas-Rodriguez E, Deming Y, Piccio L, Cruchaga C, Kleinberger G, Shaw L, Trojanowski JQ, Herms J, Dichgans M, , et al. Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation. Embo Molecular Medicine. e12308. PMID 32790063 DOI: 10.15252/emmm.202012308   
2020 Flores J, Noël A, Foveau B, Beauchet O, LeBlanc AC. Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging. Nature Communications. 11: 4571. PMID 32917871 DOI: 10.1038/s41467-020-18405-9   
2020 Burnham SC, Fandos N, Fowler C, Pérez-Grijalba V, Dore V, Doecke JD, Shishegar R, Cox T, Fripp J, Rowe C, Sarasa M, Masters CL, Pesini P, Villemagne VL. Longitudinal evaluation of the natural history of amyloid-β in plasma and brain. Brain Communications. 2: fcaa041. PMID 32954297 DOI: 10.1093/braincomms/fcaa041   
2020 Didehbani N, Fields LM, Wilmoth K, LoBue C, Hart J, Cullum CM. Mild Cognitive Impairment in Retired Professional Football Players With a History of Mild Traumatic Brain Injury: A Pilot Investigation. Cognitive and Behavioral Neurology : Official Journal of the Society For Behavioral and Cognitive Neurology. 33: 208-217. PMID 32889953 DOI: 10.1097/WNN.0000000000000240   
2020 von Saucken VE, Jay TR, Landreth GE. The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease. Neurobiology of Disease. 105072. PMID 32890775 DOI: 10.1016/j.nbd.2020.105072   
2020 Dinkel F, Trujillo-Rodriguez D, Villegas A, Streffer J, Mercken M, Lopera F, Glatzel M, Sepulveda-Falla D. Decreased Deposition of Beta-Amyloid 1-38 and Increased Deposition of Beta-Amyloid 1-42 in Brain Tissue of Presenilin-1 E280A Familial Alzheimer's Disease Patients. Frontiers in Aging Neuroscience. 12: 220. PMID 32848702 DOI: 10.3389/fnagi.2020.00220   
2020 Ledo JH, Liebmann T, Zhang R, Chang JC, Azevedo EP, Wong E, Silva HM, Troyanskaya OG, Bustos V, Greengard P. Presenilin 1 phosphorylation regulates amyloid-β degradation by microglia. Molecular Psychiatry. PMID 32792660 DOI: 10.1038/s41380-020-0856-8   
2020 Arya R, Paliwal S, Gupta SP, Sharma S, Madan K, Mishra A, Verma K, Chauhan N. In-silico studies and Biological activity of potential BACE-1 Inhibitors. Combinatorial Chemistry & High Throughput Screening. PMID 32957879 DOI: 10.2174/1386207323999200918151331   
2020 Stage EC, Svaldi D, Phillips M, Canela VH, Duran T, Goukasian N, Risacher SL, Saykin AJ, Apostolova LG, . Neurodegenerative changes in early- and late-onset cognitive impairment with and without brain amyloidosis. Alzheimer's Research & Therapy. 12: 93. PMID 32758274 DOI: 10.1186/s13195-020-00647-w   
2020 Fernández-Mendívil C, Arreola MA, Hohsfield LA, Green KN, Lopez MG. Aging and Progression of Beta-Amyloid Pathology in Alzheimer's Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression. Antioxidants (Basel, Switzerland). 9. PMID 32708329 DOI: 10.3390/antiox9070644   
2020 Fernández-Mendívil C, Arreola MA, Hohsfield LA, Green KN, Lopez MG. Aging and Progression of Beta-Amyloid Pathology in Alzheimer's Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression. Antioxidants (Basel, Switzerland). 9. PMID 32708329 DOI: 10.3390/antiox9070644   
2020 Sohrabi M, Floden AM, Manocha GD, Klug MG, Combs CK. IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer's Disease Transgenic Mouse Model. Frontiers in Cellular Neuroscience. 14: 200. PMID 32719587 DOI: 10.3389/fncel.2020.00200   
2020 Swaminathan SK, Zhou AL, Ahlschwede KM, Curran GL, Lowe VJ, Li L, Kandimalla KK. HDL mimetic peptide 4F efficiently crosses the blood-brain barrier and modulates amyloid beta distribution between brain and plasma. The Journal of Pharmacology and Experimental Therapeutics. PMID 32778535 DOI: 10.1124/jpet.120.265876   
2020 Ochi S, Iga JI, Funahashi Y, Yoshino Y, Yamazaki K, Kumon H, Mori H, Ozaki Y, Mori T, Ueno SI. Identifying Blood Transcriptome Biomarkers of Alzheimer's Disease Using Transgenic Mice. Molecular Neurobiology. PMID 32816243 DOI: 10.1007/s12035-020-02058-2   
2020 Khandelwal M, Manglani K, Gupta S, Tiku AB. Gamma radiation improves AD pathogenesis in APP/PS1 mouse model by potentiating insulin sensitivity. Heliyon. 6: e04499. PMID 32775714 DOI: 10.1016/j.heliyon.2020.e04499   
2020 Yuan Q, Yang J, Xian YF, Liu R, Chan CW, Wu W, Lin ZX. The Effect of Spinal Cord Injury on Beta-Amyloid Plaque Pathology in TgCRND8 Mouse Model of Alzheimer's Disease. Current Alzheimer Research. PMID 32851942 DOI: 10.2174/1567205017666200807191447   
2020 Liu CC, Yamazaki Y, Heckman MG, Martens YA, Jia L, Yamazaki A, Diehl NN, Zhao J, Zhao N, DeTure M, Davis MD, Felton LM, Qiao W, Li Y, Li H, et al. Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32827351 DOI: 10.1002/alz.12104   
2020 Zhao L, Li Z, Vong JSL, Chen X, Lai HM, Yan LYC, Huang J, Sy SKH, Tian X, Huang Y, Chan HYE, So HC, Ng WL, Tang Y, Lin WJ, et al. Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain. Nature Communications. 11: 4413. PMID 32887883 DOI: 10.1038/s41467-020-18249-3   
2020 Johnson ECB, Ho K, Yu GQ, Das M, Sanchez PE, Djukic B, Lopez I, Yu X, Gill M, Zhang W, Paz JT, Palop JJ, Mucke L. Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1. Molecular Neurodegeneration. 15: 53. PMID 32921309 DOI: 10.1186/s13024-020-00393-5   
2020 Luo W, Ip FCF, Fu G, Cheung K, Tian Y, Hu Y, Sinha A, Cheng EYL, Wu X, Bustos V, Greengard P, Li YM, Sinha SC, Ip NY. A pentacyclic triterpene from targets γ-secretase. Acs Chemical Neuroscience. PMID 32786303 DOI: 10.1021/acschemneuro.0c00389   
2020 Webb CE, Foster CM, Horn MM, Kennedy KM, Rodrigue KM. Beta-amyloid burden predicts poorer mnemonic discrimination in cognitively normal older adults. Neuroimage. 221: 117199. PMID 32736001 DOI: 10.1016/j.neuroimage.2020.117199   
2020 Zhao J, Liu X, Xia W, Zhang Y, Wang C. Targeting Amyloidogenic Processing of APP in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 13: 137. PMID 32848600 DOI: 10.3389/fnmol.2020.00137   
2020 Griciuc A, Federico AN, Natasan J, Forte AM, McGinty D, Nguyen H, Volak A, LeRoy S, Gandhi S, Lerner EP, Hudry E, Tanzi RE, Maguire CA. Gene therapy for Alzheimer's Disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation. Human Molecular Genetics. PMID 32803224 DOI: 10.1093/hmg/ddaa179   
2020 Storelli F, Billington S, Kumar AR, Unadkat JD. Abundance of P-glycoprotein and other drug transporters at the human blood-brain barrier in Alzheimer's Disease: a quantitative targeted proteomic study. Clinical Pharmacology and Therapeutics. PMID 32885413 DOI: 10.1002/cpt.2035   
2020 Chu TH, Cummins K, Stys PK. Traumatic Injury Reduces Amyloid Plaque Burden in the Transgenic 5xFAD Alzheimer's Mouse Spinal Cord. Journal of Alzheimer's Disease : Jad. PMID 32925040 DOI: 10.3233/JAD-200387   
2020 Taylor X, Cisternas P, You Y, You Y, Xiang S, Marambio Y, Zhang J, Vidal R, Lasagna-Reeves CA. A1 reactive astrocytes and a loss of TREM2 are associated with an early stage of pathology in a mouse model of cerebral amyloid angiopathy. Journal of Neuroinflammation. 17: 223. PMID 32711525 DOI: 10.1186/s12974-020-01900-7   
2020 de Leeuw FA, Schneider JA, Agrawal S, Leurgans SE, Morris MC. Brain tocopherol levels are associated with lower activated microglia density in elderly human cortex. Alzheimer's & Dementia (New York, N. Y.). 6: e12021. PMID 32864412 DOI: 10.1002/trc2.12021   
2020 Bennett DA, Knopman DS. Extending AD biomarker studies into the Hispanic community. Neurology. PMID 32847949 DOI: 10.1212/WNL.0000000000010714   
2020 Carare RO, Aldea R, Agarwal N, Bacskai BJ, Bechman I, Boche D, Bu G, Bulters D, Clemens A, Counts SE, de Leon M, Eide PK, Fossati S, Greenberg SM, Hamel E, et al. Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12053. PMID 32775596 DOI: 10.1002/dad2.12053   
2020 Rao CV, Farooqui M, Madhavaram A, Zhang Y, Asch AS, Yamada HY. GSK3-ARC/Arg3.1 and GSK3-Wnt signaling axes trigger amyloid-β accumulation and neuroinflammation in middle-aged Shugoshin 1 mice. Aging Cell. e13221. PMID 32857910 DOI: 10.1111/acel.13221   
2020 Tanaka N, Okuda M, Nishigaki T, Tsuchiya N, Kobayashi Y, Uemura T, Kumo S, Sugimoto H, Miyata S, Waku T. Development of a brain-permeable peptide nanofiber that prevents aggregation of Alzheimer pathogenic proteins. Plos One. 15: e0235979. PMID 32706773 DOI: 10.1371/journal.pone.0235979   
2020 Falkenhain K, Ruiz-Uribe NE, Haft-Javaherian M, Ali M, , Michelucci PE, Schaffer CB, Bracko O. A pilot study investigating the effects of voluntary exercise on capillary stalling and cerebral blood flow in the APP/PS1 mouse model of Alzheimer's disease. Plos One. 15: e0235691. PMID 32857763 DOI: 10.1371/journal.pone.0235691   
2020 Kim SH, Lee EH, Lee SC, Kim AR, Park HH, Son JW, Koh SH, Yoon MY. Development of peptide aptamers as alternatives for antibody in the detection of amyloid-beta 42 aggregates. Analytical Biochemistry. 113921. PMID 32828793 DOI: 10.1016/j.ab.2020.113921   
2020 Li C, Wang J, Liu L. Alzheimer's Therapeutic Strategy: Photoactive Platforms for Suppressing the Aggregation of Amyloid β Protein. Frontiers in Chemistry. 8: 509. PMID 32793545 DOI: 10.3389/fchem.2020.00509   
2020 Ringland C, Schweig JE, Paris D, Shackleton B, Lynch CE, Eisenbaum M, Mullan M, Crawford F, Abdullah L, Bachmeier C. Apolipoprotein E isoforms differentially regulate matrix metallopeptidase 9 function in Alzheimer's disease. Neurobiology of Aging. 95: 56-68. PMID 32758917 DOI: 10.1016/j.neurobiolaging.2020.06.018   
2020 Xia Y, Wang ZH, Liu P, Edgington-Mitchell L, Liu X, Wang XC, Ye K. TrkB receptor cleavage by delta-secretase abolishes its phosphorylation of APP, aggravating Alzheimer's disease pathologies. Molecular Psychiatry. PMID 32782380 DOI: 10.1038/s41380-020-00863-8   
2020 Burnham SC, Laws SM, Budgeon CA, Doré V, Porter T, Bourgeat P, Buckley RF, Murray K, Ellis KA, Turlach BA, Salvado O, Ames D, Martins RN, Rentz D, Masters CL, ... , ... , et al. Impact of APOE-ε4 carriage on the onset and rates of neocortical Aβ-amyloid deposition. Neurobiology of Aging. 95: 46-55. PMID 32750666 DOI: 10.1016/j.neurobiolaging.2020.06.001   
2020 Yi JH, Whitcomb DJ, Park SJ, Martinez-Perez C, Barbati SA, Mitchell SJ, Cho K. M1 muscarinic acetylcholine receptor dysfunction in moderate Alzheimer's disease pathology. Brain Communications. 2: fcaa058. PMID 32766549 DOI: 10.1093/braincomms/fcaa058   
2020 Lauwers E, Lalli G, Brandner S, Collinge J, Compernolle V, Duyckaerts C, Edgren G, Haïk S, Hardy J, Helmy A, Ivinson AJ, Jaunmuktane Z, Jucker M, Knight R, Lemmens R, et al. Potential human transmission of amyloid β pathology: surveillance and risks. The Lancet. Neurology. 19: 872-878. PMID 32949547 DOI: 10.1016/S1474-4422(20)30238-6   
2020 Giorgi FS, Galgani A, Puglisi-Allegra S, Limanaqi F, Busceti CL, Fornai F. Locus Coeruleus and neurovascular unit: From its role in physiology to its potential role in Alzheimer's disease pathogenesis. Journal of Neuroscience Research. PMID 32875628 DOI: 10.1002/jnr.24718