Zygmunt Galdzicki - Publications

Affiliations: 
Uniformed Services University of the Health Sciences, Bethesda, MD 
Area:
Down syndrome, hippocampal plasticity
Website:
http://www.usuhs.mil/nes/faculty_page.htm

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sharma R, Cramer NP, Perry B, Adahman Z, Murphy EK, Xu X, Dardzinski BJ, Galdzicki Z, Perl DP, Dickstein DL, Iacono D. Chronic Exposure to High Altitude: Synaptic, Astroglial and Memory Changes. Scientific Reports. 9: 16406. PMID 31712561 DOI: 10.1038/s41598-019-52563-1  0.96
2018 Cramer NP, Korotcov A, Bosomtwi A, Xu X, Holman D, Whiting K, Jones S, Hoy A, Dardzinski BJ, Galdzicki Z. Neuronal and vascular deficits following chronic adaptation to high altitude. Experimental Neurology. PMID 30321497 DOI: 10.1016/j.expneurol.2018.10.007  0.96
2018 Marion CM, Radomski KL, Cramer NP, Galdzicki Z, Armstrong RC. Experimental Traumatic Brain Injury Identifies Distinct Early and Late Phase Axonal Conduction Deficits of White Matter Pathophysiology, and Reveals Intervening Recovery. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30143572 DOI: 10.1523/JNEUROSCI.0819-18.2018  0.96
2016 Olmos-Serrano JL, Kang HJ, Tyler WA, Silbereis JC, Cheng F, Zhu Y, Pletikos M, Jankovic-Rapan L, Cramer NP, Galdzicki Z, Goodliffe J, Peters A, Sethares C, Delalle I, Golden JA, et al. Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination. Neuron. PMID 26924435 DOI: 10.1016/j.neuron.2016.01.042  0.96
2015 Logue OC, Cramer NP, Xu X, Perl D, Galdzicki Z. Alterations of functional properties of hippocampal networks following repetitive closed-head injury. Experimental Neurology. PMID 26730521 DOI: 10.1016/j.expneurol.2015.12.019  0.96
2015 Cramer NP, Xu X, F Haydar T, Galdzicki Z. Altered intrinsic and network properties of neocortical neurons in the Ts65Dn mouse model of Down syndrome. Physiological Reports. 3. PMID 26702072 DOI: 10.14814/phy2.12655  0.96
2015 Cramer NP, Xu X, Christensen C, Bierman A, Tankersley CG, Galdzicki Z. Strain variation in the adaptation of C57Bl6 and BALBc mice to chronic hypobaric hypoxia. Physiology & Behavior. 143: 158-65. PMID 25647362 DOI: 10.1016/j.physbeh.2015.01.036  0.96
2014 Rittase WB, Dong Y, Barksdale D, Galdzicki Z, Bausch SB. Dynorphin up-regulation in the dentate granule cell mossy fiber pathway following chronic inhibition of GluN2B-containing NMDAR is associated with increased CREB (Ser 133) phosphorylation, but is independent of BDNF/TrkB signaling pathways. Molecular and Cellular Neurosciences. 60: 63-71. PMID 24769103 DOI: 10.1016/j.mcn.2014.04.002  0.96
2013 Rusiecki JA, Byrne C, Galdzicki Z, Srikantan V, Chen L, Poulin M, Yan L, Baccarelli A. PTSD and DNA Methylation in Select Immune Function Gene Promoter Regions: A Repeated Measures Case-Control Study of U.S. Military Service Members. Frontiers in Psychiatry. 4: 56. PMID 23805108 DOI: 10.3389/fpsyt.2013.00056  0.96
2012 Cramer N, Galdzicki Z. From abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome. Neural Plasticity. 2012: 101542. PMID 22848844 DOI: 10.1155/2012/101542  0.96
2012 Best TK, Cramer NP, Chakrabarti L, Haydar TF, Galdzicki Z. Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome. Experimental Neurology. 233: 749-57. PMID 22178330 DOI: 10.1016/j.expneurol.2011.11.033  0.96
2011 Keck-Wherley J, Grover D, Bhattacharyya S, Xu X, Holman D, Lombardini ED, Verma R, Biswas R, Galdzicki Z. Abnormal microRNA expression in Ts65Dn hippocampus and whole blood: contributions to Down syndrome phenotypes. Developmental Neuroscience. 33: 451-67. PMID 22042248 DOI: 10.1159/000330884  0.96
2011 Verma R, Xu X, Jaiswal MK, Olsen C, Mears D, Caretti G, Galdzicki Z. In vitro profiling of epigenetic modifications underlying heavy metal toxicity of tungsten-alloy and its components. Toxicology and Applied Pharmacology. 253: 178-87. PMID 21513724 DOI: 10.1016/j.taap.2011.04.002  0.96
2010 Cramer NP, Best TK, Stoffel M, Siarey RJ, Galdzicki Z. GABAB-GIRK2-mediated signaling in Down syndrome. Advances in Pharmacology (San Diego, Calif.). 58: 397-426. PMID 20655490 DOI: 10.1016/S1054-3589(10)58015-3  0.96
2010 Chakrabarti L, Best TK, Cramer NP, Carney RS, Isaac JT, Galdzicki Z, Haydar TF. Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome. Nature Neuroscience. 13: 927-34. PMID 20639873 DOI: 10.1038/nn.2600  0.96
2009 Baek KH, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, Lensch MW, Park IH, Yoon SS, Minami T, Korenberg JR, Folkman J, Daley GQ, Aird WC, Galdzicki Z, et al. Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature. 459: 1126-30. PMID 19458618 DOI: 10.1038/nature08062  0.96
2008 Best TK, Cho-Clark M, Siarey RJ, Galdzicki Z. Speeding of miniature excitatory post-synaptic currents in Ts65Dn cultured hippocampal neurons. Neuroscience Letters. 438: 356-61. PMID 18490108 DOI: 10.1016/j.neulet.2008.04.039  0.96
2007 Chakrabarti L, Galdzicki Z, Haydar TF. Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11483-95. PMID 17959791 DOI: 10.1523/JNEUROSCI.3406-07.2007  0.96
2007 Olson LE, Roper RJ, Sengstaken CL, Peterson EA, Aquino V, Galdzicki Z, Siarey R, Pletnikov M, Moran TH, Reeves RH. Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice. Human Molecular Genetics. 16: 774-82. PMID 17339268 DOI: 10.1093/hmg/ddm022  0.96
2007 Best TK, Siarey RJ, Galdzicki Z. Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current. Journal of Neurophysiology. 97: 892-900. PMID 17093127 DOI: 10.1152/jn.00626.2006  0.96
2006 Siarey RJ, Kline-Burgess A, Cho M, Balbo A, Best TK, Harashima C, Klann E, Galdzicki Z. Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome. Journal of Neurochemistry. 98: 1266-77. PMID 16895585 DOI: 10.1111/j.1471-4159.2006.03971.x  0.96
2006 Harashima C, Jacobowitz DM, Stoffel M, Chakrabarti L, Haydar TF, Siarey RJ, Galdzicki Z. Elevated expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in cerebellar unipolar brush cells of a Down syndrome mouse model. Cellular and Molecular Neurobiology. 26: 719-34. PMID 16783527 DOI: 10.1007/s10571-006-9066-4  0.96
2006 Harashima C, Jacobowitz DM, Witta J, Borke RC, Best TK, Siarey RJ, Galdzicki Z. Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome. The Journal of Comparative Neurology. 494: 815-33. PMID 16374808 DOI: 10.1002/cne.20844  0.96
2005 Siarey RJ, Villar AJ, Epstein CJ, Galdzicki Z. Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome. Neuropharmacology. 49: 122-8. PMID 15992587 DOI: 10.1016/j.neuropharm.2005.02.012  0.96
2003 Galdzicki Z, Siarey RJ. Understanding mental retardation in Down's syndrome using trisomy 16 mouse models. Genes, Brain, and Behavior. 2: 167-78. PMID 12931790 DOI: 10.1034/j.1601-183X.2003.00024.x  0.96
2001 Klein RC, Warder SE, Galdzicki Z, Castellino FJ, Prorok M. Kinetic and mechanistic characterization of NMDA receptor antagonism by replacement and truncation variants of the conantokin peptides. Neuropharmacology. 41: 801-10. PMID 11684144 DOI: 10.1016/S0028-3908(01)00119-8  0.96
2001 Chikhale EG, Balbo A, Galdzicki Z, Rapoport SI, Shetty HU. Measurement of myo-inositol turnover in phosphatidylinositol: description of a model and mass spectrometric method for cultured cortical neurons. Biochemistry. 40: 11114-20. PMID 11551209 DOI: 10.1021/bi010817k  0.96
2001 Galdzicki Z, Siarey R, Pearce R, Stoll J, Rapoport SI. On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models. Brain Research. Brain Research Reviews. 35: 115-45. PMID 11336779 DOI: 10.1016/S0926-6410(00)00074-4  0.96
2001 Klein RC, Prorok M, Galdzicki Z, Castellino FJ. The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors. The Journal of Biological Chemistry. 276: 26860-7. PMID 11335724 DOI: 10.1074/jbc.M102428200  0.96
2001 Klein RC, Siarey RJ, Caruso A, Rapoport SI, Castellino FJ, Galdzicki Z. Increased expression of NR2A subunit does not alter NMDA-evoked responses in cultured fetal trisomy 16 mouse hippocampal neurons. Journal of Neurochemistry. 76: 1663-9. PMID 11259484 DOI: 10.1046/j.1471-4159.2001.00170.x  0.96
2000 Peng S, Rapoport SI, Pearce RJ, Galdzicki Z. Abnormal chloride and potassium conductances in cultured embryonic tongue muscle from trisomy 16 mouse. Brain Research. Developmental Brain Research. 122: 193-7. PMID 10960688 DOI: 10.1016/S0165-3806(00)00058-4  0.96
2000 Ehrenstein G, Galdzicki Z, Lange GD. A positive-feedback model for the loss of acetylcholine in Alzheimer's disease. Annals of the New York Academy of Sciences. 899: 283-91. PMID 10863547  0.96
2000 Shetty HU, Siarey RJ, Galdzicki Z, Stoll J, Rapoport SI. Ts65Dn mouse, a Down syndrome model, exhibits elevated myo-inositol in selected brain regions and peripheral tissues. Neurochemical Research. 25: 431-5. PMID 10823574 DOI: 10.1023/A:1007592006005  0.96
2000 Huang W, Galdzicki Z, van Gelderen P, Balbo A, Chikhale EG, Schapiro MB, Rapoport SI. Brain myo-inositol level is elevated in Ts65Dn mouse and reduced after lithium treatment. Neuroreport. 11: 445-8. PMID 10718292  0.96
1999 Siarey RJ, Carlson EJ, Epstein CJ, Balbo A, Rapoport SI, Galdzicki Z. Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome. Neuropharmacology. 38: 1917-20. PMID 10608287 DOI: 10.1016/S0028-3908(99)00083-0  0.96
1999 Klein RC, Galdzicki Z, Castellino FJ. Inhibition of NMDA-induced currents by conantokin-G and conantokin-T in cultured embryonic murine hippocampal neurons. Neuropharmacology. 38: 1819-29. PMID 10608277 DOI: 10.1016/S0028-3908(99)00065-9  0.96
1999 Scortegagna M, Galdzicki Z, Rapoport SI, Hanbauer I. Activator protein-1 DNA binding activation by hydrogen peroxide in neuronal and astrocytic primary cultures of trisomy-16 and diploid mice. Brain Research. Molecular Brain Research. 73: 144-50. PMID 10581408 DOI: 10.1016/S0169-328X(99)00257-0  0.96
1998 Hanbauer I, Galdzicki Z, Rapoport SI, Scortegagna M. Evidence of increased oxidative stress in hippocampal primary cultures of trisomy 16 mouse. Studies on metallothionein-I/II. Restorative Neurology and Neuroscience. 12: 87-93. PMID 12671302  0.96
1998 Lane NJ, Balbo A, Fukuyama R, Rapoport SI, Galdzicki Z. The ultrastructural effects of beta-amyloid peptide on cultured PC12 cells: changes in cytoplasmic and intramembranous features. Journal of Neurocytology. 27: 707-18. PMID 10640186 DOI: 10.1023/A:1006976400227  0.96
1998 Galdzicki Z, Coan EJ, Rapoport SI, Stoll J. Increased expression of voltage-activated calcium channels in cultured hippocampal neurons from mouse trisomy 16, a model for Down syndrome. Brain Research. Molecular Brain Research. 56: 200-6. PMID 9602127 DOI: 10.1016/S0169-328X(98)00046-1  0.96
1998 Scortegagna M, Galdzicki Z, Rapoport SI, Hanbauer I. In cortical cultures of trisomy 16 mouse brain the upregulated metallothionein-I/II fails to respond to H2O2 exposure or glutamate receptor stimulation. Brain Research. 787: 292-8. PMID 9518655 DOI: 10.1016/S0006-8993(97)01501-1  0.96
1997 Siarey RJ, Stoll J, Rapoport SI, Galdzicki Z. Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome. Neuropharmacology. 36: 1549-54. PMID 9517425 DOI: 10.1016/S0028-3908(97)00157-3  0.96
1997 Nelson PG, Fitzgerald S, Rapoport SI, Neale EA, Galdzicki Z, Dunlap V, Bowers L, v Agoston D. Cerebral cortical astroglia from the trisomy 16 mouse, a model for down syndrome, produce neuronal cholinergic deficits in cell culture. Proceedings of the National Academy of Sciences of the United States of America. 94: 12644-8. PMID 9356503 DOI: 10.1073/pnas.94.23.12644  0.96
1997 Allen DD, Galdzicki Z, Brining SK, Fukuyama R, Rapoport SI, Smith QR. Beta-amyloid induced increase in choline flux across PC12 cell membranes. Neuroscience Letters. 234: 71-3. PMID 9347949 DOI: 10.1016/S0304-3940(97)00671-X  0.96
1997 Siarey RJ, Coan EJ, Rapoport SI, Galdzicki Z. Responses to NMDA in cultured hippocampal neurons from trisomy 16 embryonic mice. Neuroscience Letters. 232: 131-4. PMID 9310297 DOI: 10.1016/S0304-3940(97)00581-8  0.96
1997 Ehrenstein G, Galdzicki Z, Lange GD. The choline-leakage hypothesis for the loss of acetylcholine in Alzheimer's disease. Biophysical Journal. 73: 1276-80. PMID 9284295 DOI: 10.1016/S0006-3495(97)78160-8  0.96
1996 Stoll J, Galdzicki Z. Reduced expression of voltage-gated sodium channels in neurons cultured from trisomy 16 mouse hippocampus. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 14: 749-60. PMID 8960982 DOI: 10.1016/S0736-5748(96)00051-2  0.96
1996 Shetty HU, Holloway HW, Acevedo LD, Galdzicki Z. Brain accumulation of myo-inositol in the trisomy 16 mouse, an animal model of Down's syndrome. The Biochemical Journal. 313: 31-3. PMID 8546700  0.96
1995 Acevedo LD, Galdzicki Z, McIntosh AR, Rapoport SI. Increased inward current in septal neurons from the trisomy 16 mouse, a model for Down's syndrome. Brain Research. 701: 89-98. PMID 8925303 DOI: 10.1016/0006-8993(95)00979-6  0.52
1995 Pearce R, Galdzicki Z, Rapoport SI. Decreased sensitivity to nerve growth factor of dorsal root ganglion neurons cultured from mouse trisomy 16, a model of Down's syndrome. Brain Research. 680: 108-16. PMID 7663966 DOI: 10.1016/0006-8993(95)00251-K  0.96
1994 Galdzicki Z, Fukuyama R, Wadhwani KC, Rapoport SI, Ehrenstein G. beta-Amyloid increases choline conductance of PC12 cells: possible mechanism of toxicity in Alzheimer's disease. Brain Research. 646: 332-6. PMID 8069685 DOI: 10.1016/0006-8993(94)90101-5  0.96
1994 Coan EJ, Galdzicki Z, Rapoport SI. Effects of nerve growth factor on whole-cell currents and other electrical membrane properties in cultured dorsal root ganglion neurons from normal and trisomy 16 mice. Brain Research. 650: 161-5. PMID 7953669 DOI: 10.1016/0006-8993(94)90221-6  0.96
1994 Fukuyama R, Wadhwani KC, Galdzicki Z, Rapoport SI, Ehrenstein G. beta-Amyloid polypeptide increases calcium-uptake in PC12 cells: a possible mechanism for its cellular toxicity in Alzheimer's disease. Brain Research. 667: 269-72. PMID 7697365 DOI: 10.1016/0006-8993(94)91505-9  0.96
1994 Rapoport SI, Galdzicki Z. Electrical studies of cultured fetal human trisomy 21 and mouse trisomy 16 neurons identify functional deficits that may lead to mental retardation in Down syndrome Developmental Brain Dysfunction. 7: 265-288.  0.96
1993 Galdzicki Z, Coan E, Rapoport SI. Cultured hippocampal neurons from trisomy 16 mouse, a model for Down's syndrome, have an abnormal action potential due to a reduced inward sodium current. Brain Research. 604: 69-78. PMID 8384514 DOI: 10.1016/0006-8993(93)90353-O  0.96
1991 Galdzicki Z, Lin F, Moran O, Novelli A, Puia G, Sciancalepore M. Development of voltage-dependent ionic currents in rat cerebellar granule cells grown in primary culture. The International Journal of Neuroscience. 56: 193-200. PMID 1938136 DOI: 10.3109/00207459108985416  0.96
1990 Sciancalepore M, GaÅ‚dzicki Z, Zheng X, Moran O. Kainate activated single channel currents as revealed by domoic acid. European Biophysics Journal : Ebj. 19: 63-8. PMID 1705880 DOI: 10.1007/BF00185087  0.96
1988 Galietta LJ, Galdzicki Z, Nobile M. Low Ca2+-sensitive maxi-K+ channels in human cultured fibroblasts. PflüGers Archiv : European Journal of Physiology. 413: 99-101. PMID 3217232 DOI: 10.1007/BF00581236  0.96
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