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Xinyuan Zhang, Ph.D. - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Pharmaceutical Sciences, Drug Biocrystals, Pharmacokinetics, Formulation, Drug Targeting, Drug Delivery
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Suzuki M, Jeng LJB, Chefo S, Wang Y, Price D, Li X, Wang J, Li RJ, Ma L, Yang Y, Zhang X, Zheng N, Zhang K, Joseph DB, Shroff H, et al. FDA approval summary for lonafarnib (Zokinvy) for the treatment of Hutchinson-Gilford progeria syndrome and processing-deficient progeroid laminopathies. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 36507973 DOI: 10.1016/j.gim.2022.11.003  0.38
2022 Duke ES, Stapleford L, Drezner N, Amatya AK, Mishra-Kalyani PS, Shen YL, Maxfield K, Fourie Zirkelbach J, Bi Y, Liu J, Zhang X, Wang H, Yang Y, Zheng N, Reece K, et al. FDA Approval Summary: Mobocertinib for Metastatic Non-Small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36112541 DOI: 10.1158/1078-0432.CCR-22-2072  0.352
2021 Xiong Y, Fan J, Kitabi E, Zhang X, Bi Y, Grimstein M, Yang Y, Earp JC, Zheng N, Liu J, Wang Y, Zhu H. Model Informed Drug Development Approaches to Assist New Drug Development in the COVID-19 Pandemic. Clinical Pharmacology and Therapeutics. PMID 34807992 DOI: 10.1002/cpt.2491  0.403
2021 Bi Y, Liu J, Li F, Yu J, Bhattaram A, Bewernitz M, Li RJ, Ahn J, Earp J, Ma L, Zhuang L, Yang Y, Zhang X, Zhu H, Wang Y. Model-Informed Drug Development in Pediatric Dose Selection. Journal of Clinical Pharmacology. 61: S60-S69. PMID 34185906 DOI: 10.1002/jcph.1848  0.433
2020 Narayan P, Prowell TM, Gao JJ, Fernandes LL, Li E, Jiang X, Qiu J, Fan J, Song P, Yu J, Zhang X, King-Kallimanis BL, Chen W, Ricks TK, Gong Y, et al. FDA Approval Summary: Alpelisib plus fulvestrant for patients with HR-positive, HER2-negative, PIK3CA-mutated, advanced or metastatic breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33168657 DOI: 10.1158/1078-0432.CCR-20-3652  0.349
2020 Shah M, Wedam S, Cheng J, Fiero MH, Xia H, Li F, Fan J, Zhang X, Yu J, Song P, Chen W, Ricks TK, Chen XH, Goldberg KB, Gong Y, et al. FDA Approval Summary: Tucatinib for the Treatment of Patients with Advanced or Metastatic HER2-Positive Breast Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33055172 DOI: 10.1158/1078-0432.CCR-20-2701  0.374
2020 Fan J, Zhang X, Liu J, Yang Y, Zheng N, Liu Q, Bergman K, Reynolds K, Huang SM, Zhu H, Wang Y. Connecting hydroxychloroquine in vitro antiviral activity to in vivo concentration for prediction of antiviral effect: a critical step in treating COVID-19 patients. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32435791 DOI: 10.1093/cid/ciaa623  0.359
2019 Bi Y, Liu J, Li L, Yu J, Bhattaram A, Bewernitz M, Li RJ, Liu C, Earp J, Ma L, Zhuang L, Yang Y, Zhang X, Zhu H, Wang Y. Role of Model-Informed Drug Development in Pediatric Drug Development, Regulatory Evaluation, and Labeling. Journal of Clinical Pharmacology. 59: S104-S111. PMID 31502691 DOI: 10.1002/jcph.1478  0.438
2015 Jiang W, Makhlouf F, Schuirmann DJ, Zhang X, Zheng N, Conner D, Yu LX, Lionberger R. Erratum to: A Bioequivalence Approach for Generic Narrow Therapeutic Index Drugs: Evaluation of the Reference-Scaled Approach and Variability Comparison Criterion. The Aaps Journal. PMID 25975618 DOI: 10.1208/s12248-015-9786-9  0.381
2015 Jiang W, Makhlouf F, Schuirmann DJ, Zhang X, Zheng N, Conner D, Yu LX, Lionberger R. A Bioequivalence Approach for Generic Narrow Therapeutic Index Drugs: Evaluation of the Reference-Scaled Approach and Variability Comparison Criterion. The Aaps Journal. 17: 891-901. PMID 25840883 DOI: 10.1208/s12248-015-9753-5  0.405
2014 Min KA, Zhang X, Yu JY, Rosania GR. Computational approaches to analyse and predict small molecule transport and distribution at cellular and subcellular levels. Biopharmaceutics & Drug Disposition. 35: 15-32. PMID 24218242 DOI: 10.1002/Bdd.1879  0.735
2013 Rosania GR, Shedden K, Zheng N, Zhang X. Visualizing chemical structure-subcellular localization relationships using fluorescent small molecules as probes of cellular transport. Journal of Cheminformatics. 5: 44. PMID 24093553 DOI: 10.1186/1758-2946-5-44  0.652
2013 Zhang X, Zheng N, Lionberger RA, Yu LX. Innovative approaches for demonstration of bioequivalence: the US FDA perspective. Therapeutic Delivery. 4: 725-40. PMID 23738669 DOI: 10.4155/tde.13.41  0.406
2011 Zheng N, Tsai HN, Zhang X, Rosania GR. The subcellular distribution of small molecules: from pharmacokinetics to synthetic biology. Molecular Pharmaceutics. 8: 1619-28. PMID 21805990 DOI: 10.1021/Mp200092V  0.707
2011 Zheng N, Tsai HN, Zhang X, Shedden K, Rosania GR. The subcellular distribution of small molecules: a meta-analysis. Molecular Pharmaceutics. 8: 1611-8. PMID 21774504 DOI: 10.1021/Mp200093Z  0.673
2011 Zheng N, Zhang X, Rosania GR. Effect of phospholipidosis on the cellular pharmacokinetics of chloroquine. The Journal of Pharmacology and Experimental Therapeutics. 336: 661-71. PMID 21156819 DOI: 10.1124/Jpet.110.175679  0.672
2010 Min KA, Yu F, Yang VC, Zhang X, Rosania GR. Transcellular Transport of Heparin-coated Magnetic Iron Oxide Nanoparticles (Hep-MION) Under the Influence of an Applied Magnetic Field. Pharmaceutics. 2: 119-135. PMID 21152371 DOI: 10.3390/Pharmaceutics2020119  0.7
2010 Zhang X, Zheng N, Zou P, Zhu H, Hinestroza JP, Rosania GR. Cells on pores: A simulation-driven analysis of transcellular small molecule transport Molecular Pharmaceutics. 7: 456-467. PMID 20025248 DOI: 10.1021/Mp9001969  0.691
2010 Min KA, Yu F, Yang VC, Zhang X, Rosania GR. Transcellular transport of heparin-coated magnetic iron oxide nanoparticles (Hep-MION) under the influence of an applied magnetic field Pharmaceutics. 2: 119-135. DOI: 10.3390/pharmaceutics2020119  0.677
2008 Zhang X, Zheng N, Rosania GR. Simulation-based cheminformatic analysis of organelle-targeted molecules: Lysosomotropic monobasic amines Journal of Computer-Aided Molecular Design. 22: 629-645. PMID 18338229 DOI: 10.1007/S10822-008-9194-7  0.697
2006 Zhang X, Shedden K, Rosania GR. A cell-based molecular transport simulator for pharmacokinetic prediction and cheminformatic exploration. Molecular Pharmaceutics. 3: 704-16. PMID 17140258 DOI: 10.1021/Mp060046K  0.681
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