Geeske van Woerden - Publications

Affiliations: 
Erasmus Medical Center Rotterdam, Rotterdam, Netherlands 
Area:
learning and memory

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Proietti Onori M, Koene LMC, Schäfer CB, Nellist M, de Brito van Velze M, Gao Z, Elgersma Y, van Woerden GM. RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity. Plos Biology. 19: e3001279. PMID 34038402 DOI: 10.1371/journal.pbio.3001279  0.763
2021 Proietti Onori M, van Woerden GM. Role of calcium/calmodulin-dependent kinase 2 in neurodevelopmental disorders. Brain Research Bulletin. 171: 209-220. PMID 33774142 DOI: 10.1016/j.brainresbull.2021.03.014  0.769
2021 van Woerden GM, Bos M, de Konink C, Distel B, Trezza RA, Shur NE, Barañano K, Mahida S, Chassevent A, Schreiber A, Erwin AL, Gripp KW, Rehman F, Brulleman S, Mc Cormack R, et al. TAOK1 is associated with neurodevelopmental disorder and essential for neuronal maturation and cortical development. Human Mutation. PMID 33565190 DOI: 10.1002/humu.24176  0.642
2020 Sonzogni M, Zhai P, Mientjes EJ, van Woerden GM, Elgersma Y. Assessing the requirements of prenatal UBE3A expression for rescue of behavioral phenotypes in a mouse model for Angelman syndrome. Molecular Autism. 11: 70. PMID 32948244 DOI: 10.1186/s13229-020-00376-9  0.597
2019 Tonazzini I, Van Woerden GM, Masciullo C, Mientjes EJ, Elgersma Y, Cecchini M. The role of ubiquitin ligase E3A in polarized contact guidance and rescue strategies in UBE3A-deficient hippocampal neurons. Molecular Autism. 10: 41. PMID 31798818 DOI: 10.1186/s13229-019-0293-1  0.622
2019 Heimer G, van Woerden GM, Barel O, Marek-Yagel D, Kol N, Munting BJ, Borghei M, Atawneh OM, Nissenkorn A, Rechavi G, Anikster Y, Elgersma Y, Kushner SA, Ben Zeev B. Netrin-G2 dysfunction causes a Rett-like phenotype with areflexia. Human Mutation. PMID 31692205 DOI: 10.1002/Humu.23945  0.606
2019 Avagliano Trezza R, Sonzogni M, Bossuyt SNV, Zampeta FI, Punt AM, van den Berg M, Rotaru DC, Koene LMC, Munshi ST, Stedehouder J, Kros JM, Williams M, Heussler H, de Vrij FMS, Mientjes EJ, ... van Woerden GM, et al. Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome. Nature Neuroscience. PMID 31235931 DOI: 10.1038/S41593-019-0425-0  0.626
2019 Sonzogni M, Hakonen J, Bernabé Kleijn M, Silva-Santos S, Judson MC, Philpot BD, van Woerden GM, Elgersma Y. Delayed loss of UBE3A reduces the expression of Angelman syndrome-associated phenotypes. Molecular Autism. 10: 23. PMID 31143434 DOI: 10.1186/S13229-019-0277-1  0.605
2019 Kool MJ, Onori MP, Borgesius NZ, van de Bree JE, Elgersma-Hooisma M, Nio E, Bezstarosti K, Buitendijk GHS, Aghadavoud Jolfaei M, Demmers JAA, Elgersma Y, van Woerden GM. CAMK2-dependent signaling in neurons is essential for survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31064859 DOI: 10.1523/JNEUROSCI.1341-18.2019  0.66
2018 Sonzogni M, Wallaard I, Santos SS, Kingma J, du Mee D, van Woerden GM, Elgersma Y. A behavioral test battery for mouse models of Angelman syndrome: a powerful tool for testing drugs and novel mutants. Molecular Autism. 9: 47. PMID 30220990 DOI: 10.1186/s13229-018-0231-7  0.568
2018 Onori MP, Koopal B, Everman DB, Worthington JD, Jones JR, Ploeg MA, Mientjes E, van Bon BW, Kleefstra T, Schulman H, Kushner SA, Küry S, Elgersma Y, van Woerden GM. The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function. Human Mutation. PMID 30184290 DOI: 10.1002/Humu.23647  0.586
2018 Rotaru DC, van Woerden GM, Wallaard I, Elgersma Y. Adult gene reinstatement restores the electrophysiological deficits of prefrontal cortex layer 5 neurons in a mouse model of Angelman syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30082419 DOI: 10.1523/JNEUROSCI.0083-18.2018  0.652
2017 Wang T, van Woerden GM, Elgersma Y, Borst JGG. Enhanced Transmission at the Calyx of Held Synapse in a Mouse Model for Angelman Syndrome. Frontiers in Cellular Neuroscience. 11: 418. PMID 29354033 DOI: 10.3389/fncel.2017.00418  0.646
2017 Küry S, van Woerden GM, Besnard T, Proietti Onori M, Latypova X, Towne MC, Cho MT, Prescott TE, Ploeg MA, Sanders S, Stessman HAF, Pujol A, Distel B, Robak LA, Bernstein JA, et al. De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability. American Journal of Human Genetics. 101: 768-788. PMID 29100089 DOI: 10.1016/J.Ajhg.2017.10.003  0.79
2017 Reijnders MRF, Kousi M, van Woerden GM, Klein M, Bralten J, Mancini GMS, van Essen T, Proietti-Onori M, Smeets EEJ, van Gastel M, Stegmann APA, Stevens SJC, Lelieveld SH, Gilissen C, Pfundt R, et al. Variation in a range of mTOR-related genes associates with intracranial volume and intellectual disability. Nature Communications. 8: 1052. PMID 29051493 DOI: 10.1038/S41467-017-00933-6  0.577
2017 Wallace ML, van Woerden GM, Elgersma Y, Smith SL, Philpot BD. UBE3A loss increases excitability and blunts orientation tuning in the visual cortex of Angelman syndrome model mice. Journal of Neurophysiology. jn.00618.2016. PMID 28468997 DOI: 10.1152/Jn.00618.2016  0.614
2016 Kool MJ, van de Bree JE, Bodde HE, Elgersma Y, van Woerden GM. The molecular, temporal and region-specific requirements of the beta isoform of Calcium/Calmodulin-dependent protein kinase type 2 (CAMK2B) in mouse locomotion. Scientific Reports. 6: 26989. PMID 27244486 DOI: 10.1038/srep26989  0.613
2016 Judson MC, Wallace ML, Sidorov MS, Burette AC, Gu B, van Woerden GM, King IF, Han JE, Zylka MJ, Elgersma Y, Weinberg RJ, Philpot BD. GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility. Neuron. PMID 27021170 DOI: 10.1016/j.neuron.2016.02.040  0.614
2016 Tonazzini I, Meucci S, Van Woerden GM, Elgersma Y, Cecchini M. Impaired Neurite Contact Guidance in Ubiquitin Ligase E3a (Ube3a)-Deficient Hippocampal Neurons on Nanostructured Substrates. Advanced Healthcare Materials. PMID 26845073 DOI: 10.1002/adhm.201500815  0.615
2015 Omrani A, van Woerden GM, Elgersma Y. Neurofibromin regulates HCN activity in Parvalbumin-positive interneurons. Molecular Psychiatry. 20: 1263. PMID 26487477 DOI: 10.1038/mp.2015.154  0.641
2015 Bruinsma CF, Schonewille M, Gao Z, Aronica EM, Judson MC, Philpot BD, Hoebeek FE, van Woerden GM, De Zeeuw CI, Elgersma Y. Dissociation of locomotor and cerebellar deficits in a murine Angelman syndrome model. The Journal of Clinical Investigation. 125: 4305-15. PMID 26485287 DOI: 10.1172/Jci83541  0.784
2015 Bruinsma CF, Savelberg SM, Kool MJ, Jolfaei MA, van Woerden GM, Baarends WM, Elgersma Y. An essential role for UBE2A/HR6A in learning and memory and mGLUR-dependent long-term depression. Human Molecular Genetics. PMID 26476408 DOI: 10.1093/Hmg/Ddv436  0.786
2015 Omrani A, van der Vaart T, Mientjes E, van Woerden GM, Hojjati MR, Li KW, Gutmann DH, Levelt CN, Smit AB, Silva AJ, Kushner SA, Elgersma Y. HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1. Molecular Psychiatry. PMID 25917366 DOI: 10.1038/Mp.2015.48  0.76
2015 Silva-Santos S, van Woerden GM, Bruinsma CF, Mientjes E, Jolfaei MA, Distel B, Kushner SA, Elgersma Y. Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model. The Journal of Clinical Investigation. 125: 2069-76. PMID 25866966 DOI: 10.1172/Jci80554  0.783
2015 Goorden SM, Abs E, Bruinsma CF, Riemslagh FW, van Woerden GM, Elgersma Y. Intact neuronal function in Rheb1 mutant mice: implications for TORC1-based treatments. Human Molecular Genetics. 24: 3390-8. PMID 25759467 DOI: 10.1093/Hmg/Ddv087  0.776
2014 Achterberg KG, Buitendijk GH, Kool MJ, Goorden SM, Post L, Slump DE, Silva AJ, van Woerden GM, Kushner SA, Elgersma Y. Temporal and region-specific requirements of αCaMKII in spatial and contextual learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11180-7. PMID 25143599 DOI: 10.1523/Jneurosci.0640-14.2014  0.784
2014 Gao Z, van Woerden GM, Elgersma Y, De Zeeuw CI, Hoebeek FE. Distinct roles of α- and βCaMKII in controlling long-term potentiation of GABAA-receptor mediated transmission in murine Purkinje cells. Frontiers in Cellular Neuroscience. 8: 16. PMID 24550776 DOI: 10.3389/fncel.2014.00016  0.619
2011 Borgesius NZ, van Woerden GM, Buitendijk GH, Keijzer N, Jaarsma D, Hoogenraad CC, Elgersma Y. βCaMKII plays a nonenzymatic role in hippocampal synaptic plasticity and learning by targeting αCaMKII to synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10141-8. PMID 21752990 DOI: 10.1523/JNEUROSCI.5105-10.2011  0.628
2011 van der Vaart T, van Woerden GM, Elgersma Y, de Zeeuw CI, Schonewille M. Motor deficits in neurofibromatosis type 1 mice: the role of the cerebellum. Genes, Brain, and Behavior. 10: 404-9. PMID 21352477 DOI: 10.1111/J.1601-183X.2011.00685.X  0.766
2011 Goorden SM, Hoogeveen-Westerveld M, Cheng C, van Woerden GM, Mozaffari M, Post L, Duckers HJ, Nellist M, Elgersma Y. Rheb is essential for murine development. Molecular and Cellular Biology. 31: 1672-8. PMID 21321084 DOI: 10.1128/MCB.00985-10  0.749
2009 van Woerden GM, Hoebeek FE, Gao Z, Nagaraja RY, Hoogenraad CC, Kushner SA, Hansel C, De Zeeuw CI, Elgersma Y. betaCaMKII controls the direction of plasticity at parallel fiber-Purkinje cell synapses. Nature Neuroscience. 12: 823-5. PMID 19503086 DOI: 10.1038/Nn.2329  0.58
2008 Denayer E, Ahmed T, Brems H, Van Woerden G, Borgesius NZ, Callaerts-Vegh Z, Yoshimura A, Hartmann D, Elgersma Y, D'Hooge R, Legius E, Balschun D. Spred1 is required for synaptic plasticity and hippocampus-dependent learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14443-9. PMID 19118178 DOI: 10.1523/Jneurosci.4698-08.2008  0.666
2008 Olijslagers JE, de Kloet ER, Elgersma Y, van Woerden GM, Joëls M, Karst H. Rapid changes in hippocampal CA1 pyramidal cell function via pre- as well as postsynaptic membrane mineralocorticoid receptors. The European Journal of Neuroscience. 27: 2542-50. PMID 18547242 DOI: 10.1111/j.1460-9568.2008.06220.x  0.566
2007 Goorden SM, van Woerden GM, van der Weerd L, Cheadle JP, Elgersma Y. Cognitive deficits in Tsc1+/- mice in the absence of cerebral lesions and seizures. Annals of Neurology. 62: 648-55. PMID 18067135 DOI: 10.1002/ana.21317  0.769
2007 Hojjati MR, van Woerden GM, Tyler WJ, Giese KP, Silva AJ, Pozzo-Miller L, Elgersma Y. Kinase activity is not required for alphaCaMKII-dependent presynaptic plasticity at CA3-CA1 synapses. Nature Neuroscience. 10: 1125-7. PMID 17660813 DOI: 10.1038/Nn1946  0.722
2007 van Woerden GM, Harris KD, Hojjati MR, Gustin RM, Qiu S, de Avila Freire R, Jiang YH, Elgersma Y, Weeber EJ. Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of alphaCaMKII inhibitory phosphorylation. Nature Neuroscience. 10: 280-2. PMID 17259980 DOI: 10.1038/Nn1845  0.737
2005 Kushner SA, Elgersma Y, Murphy GG, Jaarsma D, van Woerden GM, Hojjati MR, Cui Y, LeBoutillier JC, Marrone DF, Choi ES, De Zeeuw CI, Petit TL, Pozzo-Miller L, Silva AJ. Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9721-34. PMID 16237176 DOI: 10.1523/Jneurosci.2836-05.2005  0.764
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