Edward C. Stack, Ph.D. - Related publications

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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Labanca F, Ullah H, Khan H, Milella L, Xiao J, Dajic-Stevanovic Z, Jeandet P. Therapeutic and Mechanistic effects of Curcumin in Huntington's disease. Current Neuropharmacology. PMID 32442088 DOI: 10.2174/1570159X18666200522201123   
2020 Alcott CE, Yalamanchili HK, Ji P, van der Heijden ME, Saltzman A, Elrod N, Lin A, Leng M, Bhatt B, Hao S, Wang Q, Saliba A, Tang J, Malovannaya A, Wagner EJ, et al. Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation. Elife. 9. PMID 32319885 DOI: 10.7554/eLife.50895   
2020 Ou L, Przybilla MJ, Ahlat O, Kim S, Overn P, Jarnes J, O'Sullivan MG, Whitley CB. A Highly Efficacious PS Gene Editing System Corrects Metabolic and Neurological Complications of Mucopolysaccharidosis Type I. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32278382 DOI: 10.1016/j.ymthe.2020.03.018   
2020 Huang B, Ding C, Zou Q, Lu J, Wang W, Li H. Human Amniotic Fluid Mesenchymal Stem Cells Improve Ovarian Function During Physiological Aging by Resisting DNA Damage. Frontiers in Pharmacology. 11: 272. PMID 32273842 DOI: 10.3389/fphar.2020.00272   
2020 Chan G, van Hummel A, van der Hoven J, Ittner LM, Ke YD. Neurodegeneration and motor deficits in the absence of astrogliosis upon transgenic mutant TDP-43 expression in mature mice. The American Journal of Pathology. PMID 32371051 DOI: 10.1016/j.ajpath.2020.04.009   
2020 Egorova PA, Gavrilova AV, Bezprozvanny IB. Ataxic Symptoms in Huntington's Disease Transgenic Mouse Model Are Alleviated by Chlorzoxazone. Frontiers in Neuroscience. 14: 279. PMID 32317916 DOI: 10.3389/fnins.2020.00279   
2020 Li X, Zhang J, Rong H, Zhang X, Dong M. Ferulic Acid Ameliorates MPP/MPTP-Induced Oxidative Stress via ERK1/2-Dependent Nrf2 Activation: Translational Implications for Parkinson Disease Treatment. Molecular Neurobiology. PMID 32445087 DOI: 10.1007/s12035-020-01934-1   
2020 Shi Z, Li T, Liu Y, Cai T, Yao W, Jiang J, He Y, Shan L. Hepatoprotective and Anti-Oxidative Effects of Total Flavonoids From Qu Zhi Qiao (Fruit of Citrus Paradisi cv.Changshanhuyou) on Nonalcoholic Steatohepatitis and Through Nrf2-ARE Signaling Pathway. Frontiers in Pharmacology. 11: 483. PMID 32390839 DOI: 10.3389/fphar.2020.00483   
2020 Maxan A, Sciacca G, Alpaugh M, Tao Z, Breger L, Dehay B, Ling Z, Qin C, Cisbani G, Masnata M, Salem S, Lacroix S, Oueslati A, Bezard E, Cicchetti F. Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates. Neurobiology of Disease. 104951. PMID 32439599 DOI: 10.1016/j.nbd.2020.104951   
2020 Liu X, Zhao X, Wang Y, Hong J, Shi M, Pfaff D, Guo L, Tang H. Triphenyl phosphate permeates the blood brain barrier and induces neurotoxicity in mouse brain. Chemosphere. 252: 126470. PMID 32443258 DOI: 10.1016/j.chemosphere.2020.126470   
2020 Anis E, Zafeer MF, Firdaus F, Islam SN, Khan AA, Hossain MM. Perillyl Alcohol Mitigates Behavioural Changes and Limits Cell Death and Mitochondrial Changes in Unilateral 6-OHDA Lesion Model of Parkinson's Disease Through Alleviation of Oxidative Stress. Neurotoxicity Research. PMID 32394056 DOI: 10.1007/s12640-020-00213-0   
2020 Schirmer B, Rother T, Bruesch I, Bleich A, Werlein C, Jonigk D, Seifert R, Neumann D. Genetic Deficiency of the Histamine H-Receptor Reduces Experimental Colorectal Carcinogenesis in Mice. Cancers. 12. PMID 32276475 DOI: 10.3390/cancers12040912   
2020 Jaber S, Goehrig D, Bertolino P, Massemin A, Bihl F, Chabry J, Lambeau G, Vindrieux D, Bernard D. Generation of a conditional transgenic mouse model expressing human Phospholipase A2 Receptor 1. Scientific Reports. 10: 8190. PMID 32424163 DOI: 10.1038/s41598-020-64863-y   
2020 Williams VR, Konvalinka A, Song X, Zhou X, John R, Pei Y, Scholey JW. Connectivity mapping of a chronic kidney disease progression signature identified lysine deacetylases as novel therapeutic targets. Kidney International. PMID 32418621 DOI: 10.1016/j.kint.2020.01.029   
2020 Yang H, Yang S, Jing L, Huang L, Chen L, Zhao X, Yang W, Pan Y, Yin P, Qin ZS, Li S, Li XJ. Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form. Nature Communications. 11: 2582. PMID 32444599 DOI: 10.1038/s41467-020-16318-1   
2020 Albers E, Avram A, Sbroggio M, Fernandez-Capetillo O, Lopez-Contreras AJ. Supraphysiological protection from replication stress does not extend mammalian lifespan. Aging. 12. PMID 32253367 DOI: 10.18632/aging.103039   
2020 Chu C, Yu L, Henry-Berger J, Ru YF, Kocer A, Champroux A, Li ZT, He M, Xie SS, Ma WB, Ni MJ, Ni ZM, Guo YL, Fei ZL, Gou LT, et al. Knockout of glutathione peroxidase 5 down-regulates the piRNAs in the caput epididymidis of aged mice. Asian Journal of Andrology. PMID 32270769 DOI: 10.4103/aja.aja_3_20   
2020 Klein AD, González de la Vega J, Zanlungo S. Complement Component C3 Participates in Early Stages of Niemann-Pick C Mouse Liver Damage. International Journal of Molecular Sciences. 21. PMID 32244854 DOI: 10.3390/ijms21062127   
2020 You Y, Bao WL, Zhang S, Li HD, Li H, Dang WZ, Zou SI, Cao XY, Wang X, Liu LX, Jiang H, Qu L, Zheng M, Shen X. Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-dependent TFEB Signaling Pathway. Circulation Research. PMID 32316875 DOI: 10.1161/CIRCRESAHA.119.315516   
2020 Scoles DR, Dansithong W, Pflieger LT, Paul S, Gandelman M, Figueroa KP, Rigo F, Bennett CF, Pulst SM. ALS-associated genes in SCA2 mouse spinal cord transcriptomes. Human Molecular Genetics. PMID 32307524 DOI: 10.1093/hmg/ddaa072   
2020 Alqahtani S, Kobos LM, Xia L, Ferreira C, Franco J, Du X, Shannahan JH. Exacerbation of Nanoparticle-Induced Acute Pulmonary Inflammation in a Mouse Model of Metabolic Syndrome. Frontiers in Immunology. 11: 818. PMID 32457752 DOI: 10.3389/fimmu.2020.00818   
2020 Mehdizadeh M, Ashtari N, Jiao X, Rahimi Balaei M, Marzban A, Qiyami-Hour F, Kong J, Ghavami S, Marzban H. Alteration of the Dopamine Receptors' Expression in the Cerebellum of the Lysosomal Acid Phosphatase 2 Mutant (Naked-Ataxia ()) Mouse. International Journal of Molecular Sciences. 21. PMID 32326360 DOI: 10.3390/ijms21082914   
2020 Buren C, Tu G, Raymond LA. Impaired Replenishment of Cortico-Striatal Synaptic Glutamate in Huntington's Disease Mouse Model. Journal of Huntington's Disease. PMID 32310183 DOI: 10.3233/JHD-200400   
2020 Nezu M, Suzuki N. Roles of Nrf2 in Protecting the Kidney from Oxidative Damage. International Journal of Molecular Sciences. 21. PMID 32331329 DOI: 10.3390/ijms21082951   
2020 Khayrullina G, Moritz KE, Schooley JF, Fatima N, Viollet C, McCormack NM, Smyth JT, Doughty ML, Dalgard CL, Flagg TP, Burnett BG. SMN-deficiency disrupts SERCA2 expression and intracellular Ca signaling in cardiomyocytes from SMA mice and patient-derived iPSCs. Skeletal Muscle. 10: 16. PMID 32384912 DOI: 10.1186/s13395-020-00232-7   
2020 Dimitrov B, Molema F, Williams M, Schmiesing J, Mühlhausen C, Baumgartner MR, Schumann A, Kölker S. Organic acidurias: major gaps, new challenges, and a yet unfulfilled promise. Journal of Inherited Metabolic Disease. PMID 32412122 DOI: 10.1002/jimd.12254   
2020 Hsu CY, Fu SH, Chien MW, Liu YW, Chen SJ, Sytwu HK. Post-Translational Modifications of Transcription Factors Harnessing the Etiology and Pathophysiology in Colonic Diseases. International Journal of Molecular Sciences. 21. PMID 32369982 DOI: 10.3390/ijms21093207   
2020 Pfalzer AC, Wilcox JM, Codreanu SG, Totten M, Bichell TJV, Halbesma T, Umashanker P, Yang KL, Parmalee NL, Sherrod SD, Erikson KM, Harrison FE, McLean JA, Aschner M, Bowman AB. Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and manifest YAC128 mice. Metallomics : Integrated Biometal Science. PMID 32421118 DOI: 10.1039/d0mt00081g   
2020 Zhang K, Cheng H, Song L, Wei W. Inhibition of the Peroxisome Proliferator-Activated Receptor gamma Coactivator 1-alpha (PGC-1α)/Sirtuin 3 (SIRT3) Pathway Aggravates Oxidative Stress After Experimental Subarachnoid Hemorrhage. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 26: e923688. PMID 32447338 DOI: 10.12659/MSM.923688   
2020 Cordeiro LM, Machado ML, da Silva AF, Obetine Baptista FB, da Silveira TL, Soares FAA, Arantes LP. Rutin protects Huntington's disease through the insulin/IGF1 (IIS) signaling pathway and autophagy activity: Study in Caenorhabditis elegans model. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 111323. PMID 32278002 DOI: 10.1016/j.fct.2020.111323   
2020 Russo M, Sobh A, Zhang P, Longuinov A, Tagmount A, Vulpe CD, Liu B. Functional Pathway Identification with CRISPR/Cas9 Genome Wide Gene Disruption in Human Dopaminergic Neuronal Cells Following Chronic Treatment with Dieldrin. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32421776 DOI: 10.1093/toxsci/kfaa071   
2020 Ding H, Fang M, Gong Y, Li D, Zhang C, Wen G, Wu C, Yang J, Yang Y. Smad3 gene C-terminal phosphorylation site mutation aggravates CCl -induced inflammation in mice. Journal of Cellular and Molecular Medicine. PMID 32406200 DOI: 10.1111/jcmm.15385   
2020 Yin P, Liu Q, Pan Y, Yang W, Yang S, Wei W, Chen X, Hong Y, Bai D, Li XJ, Li S. Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease. Embo Reports. e49783. PMID 32270922 DOI: 10.15252/embr.201949783   
2020 Ko MS, Yun JY, Baek IJ, Jang JE, Hwang JJ, Lee SE, Heo SH, Bader DA, Lee CH, Han J, Moon JS, Lee JM, Hong EG, Lee IK, Kim SW, et al. Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice. Autophagy. 1-17. PMID 32400277 DOI: 10.1080/15548627.2020.1753002   
2020 Chu Y, Lan RS, Huang R, Feng H, Kumar R, Dayal S, Chan KS, Dai DF. Glutathione peroxidase-1 overexpression reduces oxidative stress, and improves pathology and proteome remodeling in the kidneys of old mice. Aging Cell. PMID 32400101 DOI: 10.1111/acel.13154   
2020 Sigurdsson V, Haga Y, Takei H, Mansell E, Okamatsu-Haga C, Suzuki M, Radulovic V, van der Garde M, Koide S, Soboleva S, Gåfvels M, Nittono H, Ohara A, Miharada K. Induction of blood-circulating bile acids supports recovery from myelosuppressive chemotherapy. Blood Advances. 4: 1833-1843. PMID 32365188 DOI: 10.1182/bloodadvances.2019000133   
2020 Yang Y, White E. Autophagy Suppresses TRP53/p53 and Oxidative Stress to Enable Mammalian Survival. Autophagy. PMID 32370647 DOI: 10.1080/15548627.2020.1765522   
2020 Ma KGL, Lertpiriyapong K, Piersigilli A, Dobtsis I, Wipf JRK, Littmann ER, Leiner I, Pamer EG, Ricart Arbona RJ, Lipman NS. Outbreaks of Typhlocolitis Caused by Hypervirulent Group ST1 Clostridioides difficile in Highly Immunocompromised Strains of Mice. Comparative Medicine. PMID 32404234 DOI: 10.30802/AALAS-CM-19-000109   
2020 Kasahara T, Kubota-Sakashita M, Nagatsuka Y, Hirabayashi Y, Hanasaka T, Tohyama K, Kato T. Cardiolipin is essential for early embryonic viability and mitochondrial integrity of neurons in mammals. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 1465-1480. PMID 31914590 DOI: 10.1096/fj.201901598R   
2020 Matsuno K, Nagashima S, Shiiba I, Taniwaka K, Takeda K, Tokuyama T, Ito N, Matsushita N, Fukuda T, Ishido S, Inatome R, Yanagi S. MITOL dysfunction causes dwarfism with anterior pituitary hypoplasia. Journal of Biochemistry. PMID 32302394 DOI: 10.1093/jb/mvaa050   
2020 Ribeiro MC, Moore SM, Kishi N, Macklis JD, MacDonald JL. Vitamin D supplementation rescues aberrant NF-κB pathway activation and partially ameliorates Rett syndrome phenotypes in mutant mice. Eneuro. PMID 32393583 DOI: 10.1523/ENEURO.0167-20.2020   
2020 Liu S, Huang Z, Tang A, Wu X, Aube J, Xu L, Xing C, Huang Y. Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis. Clinical Science (London, England : 1979). PMID 32478392 DOI: 10.1042/CS20200193   
2020 Berger S, Stattmann M, Cicvaric A, Monje FJ, Coiro P, Hotka M, Ricken G, Hainfellner J, Greber-Platzer S, Yasuda M, Desnick RJ, Pollak DD. Severe hydroxymethylbilane synthase deficiency causes depression-like behavior and mitochondrial dysfunction in a mouse model of homozygous dominant acute intermittent porphyria. Acta Neuropathologica Communications. 8: 38. PMID 32197664 DOI: 10.1186/s40478-020-00910-z   
2020 Broussy S, Laaroussi H, Vidal M. Biochemical mechanism and biological effects of the inhibition of silent information regulator 1 (SIRT1) by EX-527 (SEN0014196 or selisistat). Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 1124-1136. PMID 32366137 DOI: 10.1080/14756366.2020.1758691   
2020 Romeo-Guitart D, Marcos-DeJuana C, Marmolejo-Martínez-Artesero S, Navarro X, Casas C. Novel neuroprotective therapy with NeuroHeal by autophagy induction for damaged neonatal motoneurons. Theranostics. 10: 5154-5168. PMID 32308774 DOI: 10.7150/thno.43765   
2020 Merritt JK, Collins BE, Erickson KR, Dong H, Neul JL. Pharmacological readthrough of R294X Mecp2 in a novel mouse model of Rett Syndrome. Human Molecular Genetics. PMID 32469049 DOI: 10.1093/hmg/ddaa102   
2020 Murray SA, Dalbøge LS, Baquero K, Sanford CA, Misquith A, Mercer AJ, Meek TH, Guldbrandt M, Andersen B, Kievit P, Grove KL, Kutlu B. Whole transcriptome analysis and validation of metabolic pathways in subcutaneous adipose tissues during FGF21-induced weight loss in non-human primates. Scientific Reports. 10: 7287. PMID 32350364 DOI: 10.1038/s41598-020-64170-6   
2020 Singh V, Ubaid S. Role of Silent Information Regulator 1 (SIRT1) in Regulating Oxidative Stress and Inflammation. Inflammation. PMID 32410071 DOI: 10.1007/s10753-020-01242-9   
2020 Shao Z, Koh W, Ni Y, Li W, Agatisa-Boyle B, Merkurjev D, Tang WHW. RNA Sequence Analyses throughout the Course of Mouse Cardiac Laminopathy Identify Differentially Expressed Genes for Cell Cycle Control and Mitochondrial Function. Scientific Reports. 10: 6632. PMID 32313136 DOI: 10.1038/s41598-020-63563-x   
2020 Ahmed SS, Rubin H, Wang M, Faulkner D, Sengooba A, Dollive SN, Avila N, Ellsworth JL, Lamppu D, Lobikin M, Lotterhand J, Adamson-Small L, Wright T, Seymour A, Francone OL. Sustained Correction of a Murine Model of Phenylketonuria following a Single Intravenous Administration of AAVHSC15-PAH. Molecular Therapy. Methods & Clinical Development. 17: 568-580. PMID 32258219 DOI: 10.1016/j.omtm.2020.03.009