Nicholas F. Lahens, Ph.D. - Publications

Genomics and Computational Biology University of Pennsylvania, Philadelphia, PA, United States 
Circadian Rhythms, Functional Genomics

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lee Y, Fong SY, Shon J, Zhang SL, Brooks R, Lahens NF, Chen D, Dang CV, Field JM, Sehgal A. Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle. Science Advances. 7. PMID 33579708 DOI: 10.1126/sciadv.abd2645  1
2021 Zhang SL, Lahens NF, Yue Z, Arnold DM, Pakstis PP, Schwarz JE, Sehgal A. A circadian clock regulates efflux by the blood-brain barrier in mice and human cells. Nature Communications. 12: 617. PMID 33504784 DOI: 10.1038/s41467-020-20795-9  1
2019 Sarantopoulou D, Tang SY, Ricciotti E, Lahens NF, Lekkas D, Schug J, Guo XS, Paschos GK, FitzGerald GA, Pack AI, Grant GR. Comparative evaluation of RNA-Seq library preparation methods for strand-specificity and low input. Scientific Reports. 9: 13477. PMID 31530843 DOI: 10.1038/S41598-019-49889-1  1
2019 Lee Y, Lahens NF, Zhang S, Bedont J, Field JM, Sehgal A. G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment. Plos Biology. 17: e3000228. PMID 31039152 DOI: 10.1371/Journal.Pbio.3000228  1
2019 Theken KN, Hersh EV, Lahens NF, Lee HM, Li X, Granquist EJ, Giannakopoulos H, Levin LM, Secreto SA, Grant GR, Detre JA, FitzGerald GA, Grosser T, Farrar JT. Variability in the Analgesic Response to Ibuprofen is Associated with Cyclooxygenase Activation in Inflammatory Pain. Clinical Pharmacology and Therapeutics. PMID 30929268 DOI: 10.1002/Cpt.1446  1
2018 Manners MT, Yohn NL, Lahens NF, Grant GR, Bartolomei MS, Blendy JA. Transgenerational inheritance of chronic adolescent stress: Effects of stress response and the amygdala transcriptome. Genes, Brain, and Behavior. e12493. PMID 29896789 DOI: 10.1111/Gbb.12493  1
2018 Terry EE, Zhang X, Hoffmann C, Hughes LD, Lewis SA, Li J, Wallace MJ, Riley L, Douglas CM, Gutierrez-Montreal MA, Lahens NF, Gong MC, Andrade F, Esser KA, Hughes ME. Transcriptional profiling reveals extraordinary diversity among skeletal muscle tissues. Elife. 7. PMID 29809149 DOI: 10.7554/Elife.34613  1
2017 Norton S, Vaquero-Garcia J, Lahens NF, Grant GR, Barash Y. Outlier detection for improved differential splicing quantification from RNA-Seq experiments with replicates. Bioinformatics (Oxford, England). PMID 29236961 DOI: 10.1093/Bioinformatics/Btx790  1
2017 Skarke C, Lahens NF, Rhoades SD, Campbell A, Bittinger K, Bailey A, Hoffmann C, Olson RS, Chen L, Yang G, Price TS, Moore JH, Bushman FD, Greene CS, Grant GR, et al. A Pilot Characterization of the Human Chronobiome. Scientific Reports. 7: 17141. PMID 29215023 DOI: 10.1038/S41598-017-17362-6  1
2017 Lahens NF, Ricciotti E, Smirnova O, Toorens E, Kim EJ, Baruzzo G, Hayer KE, Ganguly T, Schug J, Grant GR. A comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expression. Bmc Genomics. 18: 602. PMID 28797240 DOI: 10.1186/S12864-017-4011-0  1
2017 Babb PL, Lahens NF, Correa-Garhwal SM, Nicholson DN, Kim EJ, Hogenesch JB, Kuntner M, Higgins L, Hayashi CY, Agnarsson I, Voight BF. The Nephila clavipes genome highlights the diversity of spider silk genes and their complex expression. Nature Genetics. PMID 28459453 DOI: 10.1038/Ng.3852  1
2016 Vaquero-Garcia J, Barrera A, Gazzara MR, González-Vallinas J, Lahens NF, Hogenesch JB, Lynch KW, Barash Y. A new view of transcriptome complexity and regulation through the lens of local splicing variations. Elife. 5. PMID 26829591 DOI: 10.7554/Elife.11752  1
2015 Hayer KE, Pizarro A, Lahens NF, Hogenesch JB, Grant GR. Benchmark analysis of algorithms for determining and quantifying full-length mRNA splice forms from RNA-seq data. Bioinformatics (Oxford, England). 31: 3938-45. PMID 26338770 DOI: 10.1093/Bioinformatics/Btv488  1
2015 Jang C, Lahens NF, Hogenesch JB, Sehgal A. Ribosome profiling reveals an important role for translational control in circadian gene expression. Genome Research. 25: 1836-47. PMID 26338483 DOI: 10.1101/Gr.191296.115  1
2014 Toung JM, Lahens N, Hogenesch JB, Grant G. Detection theory in identification of RNA-DNA sequence differences using RNA-sequencing. Plos One. 9: e112040. PMID 25396741 DOI: 10.1371/Journal.Pone.0112040  1
2014 Zhang R, Lahens NF, Ballance HI, Hughes ME, Hogenesch JB. A circadian gene expression atlas in mammals: implications for biology and medicine. Proceedings of the National Academy of Sciences of the United States of America. 111: 16219-24. PMID 25349387 DOI: 10.1073/Pnas.1408886111  1
2014 Lahens NF, Kavakli IH, Zhang R, Hayer K, Black MB, Dueck H, Pizarro A, Kim J, Irizarry R, Thomas RS, Grant GR, Hogenesch JB. IVT-seq reveals extreme bias in RNA sequencing. Genome Biology. 15: R86. PMID 24981968 DOI: 10.1186/Gb-2014-15-6-R86  1
2013 Pizarro A, Hayer K, Lahens NF, Hogenesch JB. CircaDB: a database of mammalian circadian gene expression profiles. Nucleic Acids Research. 41: D1009-13. PMID 23180795 DOI: 10.1093/Nar/Gks1161  1
2011 Grant GR, Farkas MH, Pizarro AD, Lahens NF, Schug J, Brunk BP, Stoeckert CJ, Hogenesch JB, Pierce EA. Comparative analysis of RNA-Seq alignment algorithms and the RNA-Seq unified mapper (RUM). Bioinformatics (Oxford, England). 27: 2518-28. PMID 21775302 DOI: 10.1093/Bioinformatics/Btr427  1
Show low-probability matches.