Year |
Citation |
Score |
2024 |
Matsuda R, Sorobetea D, Zhang J, Peterson ST, Grayczyk JP, Yost W, Apenes N, Kovalik ME, Herrmann B, O'Neill RJ, Bohrer AC, Lanza M, Assenmacher CA, Mayer-Barber KD, Shin S, ... Brodsky IE, et al. A TNF-IL-1 circuit controls Yersinia within intestinal pyogranulomas. The Journal of Experimental Medicine. 221. PMID 38363547 DOI: 10.1084/jem.20230679 |
0.338 |
|
2023 |
Wertman RS, Go CK, Saller BS, Groß O, Scott P, Brodsky IE. Sequentially activated death complexes regulate pyroptosis and IL-1β release in response to blockade of immune signaling. Biorxiv : the Preprint Server For Biology. PMID 37745613 DOI: 10.1101/2023.09.14.557714 |
0.32 |
|
2023 |
Herrmann BI, Grayczyk JP, Brodsky IE. Collab or Cancel? Bacterial Influencers of Inflammasome Signaling. Annual Review of Microbiology. 77: 451-477. PMID 37713455 DOI: 10.1146/annurev-micro-032521-024017 |
0.39 |
|
2023 |
Zhang J, Brodsky IE, Shin S. deploys type III-secreted effectors to evade caspase-4 inflammasome activation in human cells. Mbio. e0131023. PMID 37615436 DOI: 10.1128/mbio.01310-23 |
0.404 |
|
2023 |
Egan MS, O'Rourke EA, Mageswaran SK, Zuo B, Martynyuk I, Demissie T, Hunter EN, Bass AR, Chang YW, Brodsky IE, Shin S. Inflammasomes primarily restrict cytosolic replication within human macrophages. Biorxiv : the Preprint Server For Biology. PMID 37503120 DOI: 10.1101/2023.07.17.549348 |
0.41 |
|
2023 |
Pollock TY, Vázquez Marrero VR, Brodsky IE, Shin S. TNF licenses macrophages to undergo rapid caspase-1, -11, and -8-mediated cell death that restricts Legionella pneumophila infection. Plos Pathogens. 19: e1010767. PMID 37279255 DOI: 10.1371/journal.ppat.1010767 |
0.375 |
|
2023 |
Matsuda R, Sorobetea D, Zhang J, Peterson ST, Grayczyk JP, Herrmann B, Yost W, O'Neill R, Bohrer AC, Lanza M, Assenmacher CA, Mayer-Barber KD, Shin S, Brodsky IE. A TNF-IL-1 circuit controls within intestinal granulomas. Biorxiv : the Preprint Server For Biology. PMID 37197029 DOI: 10.1101/2023.04.21.537749 |
0.344 |
|
2023 |
Sorobetea D, Matsuda R, Peterson ST, Grayczyk JP, Rao I, Krespan E, Lanza M, Assenmacher CA, Mack M, Beiting DP, Radaelli E, Brodsky IE. Inflammatory monocytes promote granuloma control of Yersinia infection. Nature Microbiology. 8: 666-678. PMID 36879169 DOI: 10.1038/s41564-023-01338-6 |
0.355 |
|
2023 |
Zhang J, Brodsky IE, Shin S. Type III-Secreted Effectors Subvert Caspase-4-dependent Inflammasome Activation in Human Cells. Biorxiv : the Preprint Server For Biology. PMID 36747770 DOI: 10.1101/2023.01.24.525473 |
0.385 |
|
2022 |
Chen KW, Brodsky IE. Yersinia interactions with regulated cell death pathways. Current Opinion in Microbiology. 71: 102256. PMID 36584489 DOI: 10.1016/j.mib.2022.102256 |
0.397 |
|
2022 |
Naseer N, Zhang J, Bauer R, Constant DA, Nice TJ, Brodsky IE, Rauch I, Shin S. Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells. Infection and Immunity. e0066321. PMID 35678562 DOI: 10.1128/iai.00663-21 |
0.402 |
|
2022 |
Naseer N, Egan MS, Reyes Ruiz VM, Scott WP, Hunter EN, Demissie T, Rauch I, Brodsky IE, Shin S. Human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella type III secretion system activities to restrict intracellular bacterial replication. Plos Pathogens. 18: e1009718. PMID 35073381 DOI: 10.1371/journal.ppat.1009718 |
0.359 |
|
2021 |
Bliska JB, Brodsky IE, Mecsas J. Role of the Yersinia pseudotuberculosis Virulence Plasmid in Pathogen-Phagocyte Interactions in Mesenteric Lymph Nodes. Ecosal Plus. 9: eESP00142021. PMID 34910573 DOI: 10.1128/ecosalplus.ESP-0014-2021 |
0.37 |
|
2021 |
Bjanes E, Sillas RG, Matsuda R, Demarco B, Fettrelet T, DeLaney AA, Kornfeld OS, Lee BL, Rodríguez López EM, Grubaugh D, Wynosky-Dolfi MA, Philip NH, Krespan E, Tovar D, Joannas L, ... ... Brodsky IE, et al. Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection. Plos Pathogens. 17: e1009967. PMID 34648590 DOI: 10.1371/journal.ppat.1009967 |
0.406 |
|
2021 |
Chen KW, Demarco B, Ramos S, Heilig R, Goris M, Grayczyk JP, Assenmacher CA, Radaelli E, Joannas LD, Henao-Mejia J, Tacchini-Cottier F, Brodsky IE, Broz P. RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34260403 DOI: 10.1073/pnas.2101189118 |
0.408 |
|
2021 |
Chen KW, Demarco B, Ramos S, Heilig R, Goris M, Grayczyk JP, Assenmacher CA, Radaelli E, Joannas LD, Henao-Mejia J, Tacchini-Cottier F, Brodsky IE, Broz P. RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34260403 DOI: 10.1073/pnas.2101189118 |
0.408 |
|
2021 |
Sateriale A, Gullicksrud JA, Engiles JB, McLeod BI, Kugler EM, Henao-Mejia J, Zhou T, Ring AM, Brodsky IE, Hunter CA, Striepen B. The intestinal parasite is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33372132 DOI: 10.1073/pnas.2007807118 |
0.341 |
|
2020 |
Monack DM, Brodsky IE. Editorial overview: The fortunate students, a tribute to the fortunate professor. Current Opinion in Microbiology. PMID 32171689 DOI: 10.1016/J.Mib.2020.02.001 |
0.439 |
|
2020 |
Peterson LW, Brodsky IE. To catch a thief: regulated RIPK1 post-translational modifications as a fail-safe system to detect and overcome pathogen subversion of immune signaling. Current Opinion in Microbiology. 54: 111-118. PMID 32092691 DOI: 10.1016/j.mib.2020.01.015 |
0.385 |
|
2019 |
Zwack EE, Brodsky IE. Analysis of Inflammasome Activation in Response to Yersinia Infection by Fluorescence Microscopy Detection of Active Caspase-1 Puncta. Methods in Molecular Biology (Clifton, N.J.). 2010: 231-240. PMID 31177442 DOI: 10.1007/978-1-4939-9541-7_16 |
0.347 |
|
2019 |
DeLaney AA, Berry CT, Christian DA, Hart A, Bjanes E, Wynosky-Dolfi MA, Li X, Tummers B, Udalova IA, Chen YH, Hershberg U, Freedman BD, Hunter CA, Brodsky IE. Caspase-8 promotes c-Rel-dependent inflammatory cytokine expression and resistance against . Proceedings of the National Academy of Sciences of the United States of America. PMID 31147458 DOI: 10.1073/Pnas.1820529116 |
0.384 |
|
2018 |
Sorobetea D, Brodsky IE. HVEM LIGHTs the Way for ILC3s. Cell Host & Microbe. 24: 187-188. PMID 30092193 DOI: 10.1016/j.chom.2018.07.010 |
0.32 |
|
2018 |
Ingram JP, Tursi S, Zhang T, Guo W, Yin C, A Wynosky-Dolfi M, van der Heijden J, Cai KQ, Yamamoto M, Finlay BB, Brodsky IE, Grivennikov SI, Tükel Ç, Balachandran S. A Nonpyroptotic IFN-γ-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Clearance In Vivo. Journal of Immunology (Baltimore, Md. : 1950). PMID 29654208 DOI: 10.4049/jimmunol.1701386 |
0.511 |
|
2017 |
Mantegazza AR, Wynosky-Dolfi MA, Casson CN, Lefkovith AJ, Shin S, Brodsky IE, Marks MS. Increased autophagic sequestration in adaptor protein-3 deficient dendritic cells limits inflammasome activity and impairs antibacterial immunity. Plos Pathogens. 13: e1006785. PMID 29253868 DOI: 10.1371/Journal.Ppat.1006785 |
0.317 |
|
2017 |
Peterson LW, Philip NH, DeLaney A, Wynosky-Dolfi MA, Asklof K, Gray F, Choa R, Bjanes E, Buza EL, Hu B, Dillon CP, Green DR, Berger SB, Gough PJ, Bertin J, ... Brodsky IE, et al. RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense. The Journal of Experimental Medicine. PMID 28855241 DOI: 10.1084/Jem.20170347 |
0.383 |
|
2017 |
Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE. NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8. Immunity. PMID 28410991 DOI: 10.1016/J.Immuni.2017.03.016 |
0.36 |
|
2016 |
Ingram JP, Brodsky IE, Balachandran S. Interferon-γ in Salmonella pathogenesis: New tricks for an old dog. Cytokine. PMID 27773552 DOI: 10.1016/j.cyto.2016.10.009 |
0.349 |
|
2016 |
Philip NH, DeLaney A, Peterson LW, Santos-Marrero M, Grier JT, Sun Y, Wynosky-Dolfi MA, Zwack EE, Hu B, Olsen TM, Rongvaux A, Pope SD, López CB, Oberst A, Beiting DP, ... ... Brodsky IE, et al. Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death. Plos Pathogens. 12: e1005910. PMID 27737018 DOI: 10.1371/Journal.Ppat.1005910 |
0.711 |
|
2016 |
Peterson LW, Philip NH, Dillon CP, Bertin J, Gough PJ, Green DR, Brodsky IE. Cell-Extrinsic TNF Collaborates with TRIF Signaling To Promote Yersinia-Induced Apoptosis. Journal of Immunology (Baltimore, Md. : 1950). PMID 27733552 DOI: 10.4049/Jimmunol.1601294 |
0.393 |
|
2016 |
Chung LK, Park YH, Zheng Y, Brodsky IE, Hearing P, Kastner DL, Chae JJ, Bliska JB. The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome. Cell Host & Microbe. PMID 27569559 DOI: 10.1016/J.Chom.2016.07.018 |
0.326 |
|
2016 |
Philip NH, Zwack EE, Brodsky IE. Activation and Evasion of Inflammasomes by Yersinia. Current Topics in Microbiology and Immunology. 397: 69-90. PMID 27460805 DOI: 10.1007/978-3-319-41171-2_4 |
0.42 |
|
2015 |
Rosadini CV, Zanoni I, Odendall C, Green ER, Paczosa MK, Philip NH, Brodsky IE, Mecsas J, Kagan JC. A Single Bacterial Immune Evasion Strategy Dismantles Both MyD88 and TRIF Signaling Pathways Downstream of TLR4. Cell Host & Microbe. 18: 682-93. PMID 26651944 DOI: 10.1016/J.Chom.2015.11.006 |
0.369 |
|
2015 |
Shin S, Brodsky IE. The inflammasome: Learning from bacterial evasion strategies. Seminars in Immunology. 27: 102-110. PMID 25914126 DOI: 10.1016/J.Smim.2015.03.006 |
0.39 |
|
2014 |
Nish SA, Schenten D, Wunderlich FT, Pope SD, Gao Y, Hoshi N, Yu S, Yan X, Lee HK, Pasman L, Brodsky I, Yordy B, Zhao H, Brüning J, Medzhitov R. T cell-intrinsic role of IL-6 signaling in primary and memory responses. Elife. 3: e01949. PMID 24842874 DOI: 10.7554/Elife.01949 |
0.686 |
|
2014 |
Philip NH, Dillon CP, Snyder AG, Fitzgerald P, Wynosky-Dolfi MA, Zwack EE, Hu B, Fitzgerald L, Mauldin EA, Copenhaver AM, Shin S, Wei L, Parker M, Zhang J, Oberst A, ... ... Brodsky IE, et al. Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: 7385-90. PMID 24799700 DOI: 10.1073/Pnas.1403252111 |
0.367 |
|
2014 |
Wynosky-Dolfi MA, Snyder AG, Philip NH, Doonan PJ, Poffenberger MC, Avizonis D, Zwack EE, Riblett AM, Hu B, Strowig T, Flavell RA, Jones RG, Freedman BD, Brodsky IE. Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome. The Journal of Experimental Medicine. 211: 653-68. PMID 24638169 DOI: 10.1084/Jem.20130627 |
0.372 |
|
2014 |
Bezbradica JS, Rosenstein RK, DeMarco RA, Brodsky I, Medzhitov R. A role for the ITAM signaling module in specifying cytokine-receptor functions. Nature Immunology. 15: 333-42. PMID 24608040 DOI: 10.1038/Ni.2845 |
0.543 |
|
2014 |
Beiting DP, Peixoto L, Akopyants NS, Beverley SM, Wherry EJ, Christian DA, Hunter CA, Brodsky IE, Roos DS. Differential induction of TLR3-dependent innate immune signaling by closely related parasite species. Plos One. 9: e88398. PMID 24505488 DOI: 10.1371/Journal.Pone.0088398 |
0.359 |
|
2014 |
Schenten D, Nish SA, Yu S, Yan X, Lee HK, Brodsky I, Pasman L, Yordy B, Wunderlich FT, Brüning JC, Zhao H, Medzhitov R. Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells. Immunity. 40: 78-90. PMID 24439266 DOI: 10.1016/J.Immuni.2013.10.023 |
0.581 |
|
2014 |
Nish SA, Schenten D, Thomas Wunderlich F, Pope SD, Gao Y, Hoshi N, Yu S, Yan X, Lee HK, Pasman L, Brodsky I, Yordy B, Zhao H, Brüning J, Medzhitov R. Author response Elife. 2014. DOI: 10.7554/Elife.01949.025 |
0.663 |
|
2013 |
Bliska JB, Wang X, Viboud GI, Brodsky IE. Modulation of innate immune responses by Yersinia type III secretion system translocators and effectors. Cellular Microbiology. 15: 1622-31. PMID 23834311 DOI: 10.1111/Cmi.12164 |
0.36 |
|
2013 |
Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE, Shin S. Caspase-11 activation in response to bacterial secretion systems that access the host cytosol. Plos Pathogens. 9: e1003400. PMID 23762026 DOI: 10.1371/Journal.Ppat.1003400 |
0.347 |
|
2013 |
Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE, Shin S. 37 Cytokine. 63: 252. DOI: 10.1016/J.Cyto.2013.06.040 |
0.323 |
|
2012 |
Philip NH, Brodsky IE. Cell death programs in Yersinia immunity and pathogenesis. Frontiers in Cellular and Infection Microbiology. 2: 149. PMID 23226685 DOI: 10.3389/fcimb.2012.00149 |
0.399 |
|
2011 |
Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB. A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages. Plos Pathogens. 7: e1002026. PMID 21533069 DOI: 10.1371/Journal.Ppat.1002026 |
0.63 |
|
2011 |
Brodsky IE, Medzhitov R. Pyroptosis: macrophage suicide exposes hidden invaders. Current Biology : Cb. 21: R72-5. PMID 21256438 DOI: 10.1016/J.Cub.2010.12.008 |
0.592 |
|
2010 |
Brodsky IE, Palm NW, Sadanand S, Ryndak MB, Sutterwala FS, Flavell RA, Bliska JB, Medzhitov R. A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system. Cell Host & Microbe. 7: 376-87. PMID 20478539 DOI: 10.1016/J.Chom.2010.04.009 |
0.593 |
|
2009 |
Brodsky IE, Monack D. NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens. Seminars in Immunology. 21: 199-207. PMID 19539499 DOI: 10.1016/J.Smim.2009.05.007 |
0.677 |
|
2009 |
Brodsky IE, Medzhitov R. Targeting of immune signalling networks by bacterial pathogens. Nature Cell Biology. 11: 521-6. PMID 19404331 DOI: 10.1038/Ncb0509-521 |
0.607 |
|
2008 |
Brodsky IE, Medzhitov R. Reduced secretion of YopJ by Yersinia limits in vivo cell death but enhances bacterial virulence. Plos Pathogens. 4: e1000067. PMID 18483548 DOI: 10.1371/Journal.Ppat.1000067 |
0.607 |
|
2007 |
Brodsky I, Medzhitov R. Two modes of ligand recognition by TLRs. Cell. 130: 979-81. PMID 17889640 DOI: 10.1016/J.Cell.2007.09.009 |
0.512 |
|
2005 |
Brodsky IE, Gunn JS. A bacterial sensory system that activates resistance to innate immune defenses: potential targets for antimicrobial therapeutics. Molecular Interventions. 5: 335-7. PMID 16394247 DOI: 10.1124/Mi.5.6.4 |
0.434 |
|
2005 |
Brodsky IE, Ghori N, Falkow S, Monack D. Mig-14 is an inner membrane-associated protein that promotes Salmonella typhimurium resistance to CRAMP, survival within activated macrophages and persistent infection. Molecular Microbiology. 55: 954-72. PMID 15661016 DOI: 10.1111/J.1365-2958.2004.04444.X |
0.67 |
|
2004 |
Prouty AM, Brodsky IE, Manos J, Belas R, Falkow S, Gunn JS. Transcriptional regulation of Salmonella enterica serovar Typhimurium genes by bile. Fems Immunology and Medical Microbiology. 41: 177-85. PMID 15145463 DOI: 10.1016/J.Femsim.2004.03.002 |
0.524 |
|
2004 |
Prouty AM, Brodsky IE, Falkow S, Gunn JS. Bile-salt-mediated induction of antimicrobial and bile resistance in Salmonella typhimurium. Microbiology (Reading, England). 150: 775-83. PMID 15073288 DOI: 10.1099/Mic.0.26769-0 |
0.519 |
|
2003 |
Detweiler CS, Monack DM, Brodsky IE, Mathew H, Falkow S. virK, somA and rcsC are important for systemic Salmonella enterica serovar Typhimurium infection and cationic peptide resistance. Molecular Microbiology. 48: 385-400. PMID 12675799 DOI: 10.1046/J.1365-2958.2003.03455.X |
0.659 |
|
2002 |
Brodsky IE, Ernst RK, Miller SI, Falkow S. mig-14 is a Salmonella gene that plays a role in bacterial resistance to antimicrobial peptides. Journal of Bacteriology. 184: 3203-13. PMID 12029036 DOI: 10.1128/Jb.184.12.3203-3213.2002 |
0.53 |
|
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