Joshua D. Sieber, Ph.D. - Publications

Affiliations: 
Boston College, Newton, MA, United States 
Area:
organic synthesis, methodology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Collins S, Sieber JD. Development of regiodivergent asymmetric reductive coupling reactions of allenamides to access heteroatom-rich organic compounds. Chemical Communications (Cambridge, England). 59: 10087-10100. PMID 37529849 DOI: 10.1039/d3cc03013j  0.356
2023 Klake RK, Sieber JD. Aminoalcohol Synthesis through Nonprecious Metal Catalysis: Enantioselective Cu-Catalyzed Reductive Coupling of Aldehydes and Allenamides. Organic Letters. PMID 37345963 DOI: 10.1021/acs.orglett.3c01698  0.861
2023 Gargaro SL, Klake RK, Sieber JD. Asymmetric Access to Boryl-Substituted Vicinal Aminoalcohols through Cu-Catalyzed Reductive Coupling. Organic Letters. PMID 37338397 DOI: 10.1021/acs.orglett.3c01459  0.791
2023 Collins S, Sieber JD. Studies Toward Improved Enantiocontrol in the Asymmetric Cu-Catalyzed Reductive Coupling of Ketones and Allenamides: 1,2-Aminoalcohol Synthesis. Organic Letters. 25: 1425-1430. PMID 36847445 DOI: 10.1021/acs.orglett.3c00157  0.66
2022 Agrawal T, Perez-Morales KD, Cort JA, Sieber JD. Asymmetric Synthesis of Propargylic α-Stereogenic Tertiary Amines by Reductive Alkynylation of Tertiary Amides Using Ir/Cu Tandem Catalysis. The Journal of Organic Chemistry. 87: 6387-6392. PMID 35435681 DOI: 10.1021/acs.joc.2c00131  0.65
2022 Gopalsamuthiram V, Ho DB, Peck CL, Natarajan V, Agrawal T, Burns JM, Bachert J, Cook DW, Stringham RW, Nelson R, Ahmad S, Gupton BF, Snead DR, McQuade DT, Vaidyanathan R, ... ... Sieber JD, et al. Development of a Practical Synthesis of the Fragment of OPC-167832. Acs Omega. 7: 7223-7228. PMID 35252712 DOI: 10.1021/acsomega.1c06996  0.393
2021 Ho DB, Gargaro S, Klake RK, Sieber JD. Development of a Modified System to Provide Improved Diastereocontrol in the Linear-Selective Cu-Catalyzed Reductive Coupling of Ketones and Allenamides. The Journal of Organic Chemistry. PMID 34807603 DOI: 10.1021/acs.joc.1c02062  0.793
2021 Klake RK, Edwards MD, Sieber JD. Synthesis of 1,2-Aminoalcohols through Enantioselective Aminoallylation of Ketones by Cu-Catalyzed Reductive Coupling. Organic Letters. PMID 34347500 DOI: 10.1021/acs.orglett.1c02258  0.855
2021 Agrawal T, Martin RT, Collins S, Wilhelm Z, Edwards MD, Gutierrez O, Sieber JD. Access to Chiral Diamine Derivatives through Stereoselective Cu-Catalyzed Reductive Coupling of Imines and Allenamides. The Journal of Organic Chemistry. PMID 33724828 DOI: 10.1021/acs.joc.0c02971  0.702
2020 Paymode DJ, Cardoso FSP, Agrawal T, Tomlin JW, Cook DW, Burns JM, Stringham RW, Sieber JD, Gupton BF, Snead DR. Expanding Access to Remdesivir via an Improved Pyrrolotriazine Synthesis: Supply Centered Synthesis. Organic Letters. PMID 32931286 DOI: 10.1021/Acs.Orglett.0C02848  0.452
2019 Gargaro SL, Klake RK, Burns KL, Elele SO, Gentry SL, Sieber JD. Access to a Catalytically Generated Umpolung Reagent through the Use of Cu-Catalyzed Reductive Coupling of Ketones and Allenes for the Synthesis of Chiral Vicinal Aminoalcohol Synthons. Organic Letters. PMID 31769994 DOI: 10.1021/Acs.Orglett.9B03937  0.804
2019 Klake RK, Gargaro SL, Gentry SL, Elele SO, Sieber JD. Development of a Strategy for Linear-Selective Cu-Catalyzed Reductive Coupling of Ketones and Allenes for the Synthesis of Chiral γ-Hydroxyaldehyde Equivalents. Organic Letters. PMID 31532684 DOI: 10.1021/Acs.Orglett.9B02973  0.801
2019 Sieber JD, Buono F, Brusoe A, Desrosiers JN, Haddad N, Lorenz JC, Xu Y, Wu H, Zhang L, Han ZS, Roschangar F, Song JJ, Yee NK, Senanayake CH. Application of a Preformed Pd-BIDIME Precatalyst to Suzuki-Miyaura Cross-Coupling Reaction in Flow. The Journal of Organic Chemistry. PMID 30715884 DOI: 10.1021/Acs.Joc.8B03040  0.451
2018 Patel ND, Sieber JD, Tcyrulnikov S, Simmons BJ, Rivalti D, Duvvuri K, Zhang Y, Gao DA, Fandrick KR, Haddad N, Lao KS, Mangunuru HPR, Biswas S, Qu B, Grinberg N, et al. Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra-Substituted Biaryl Synthesis. Acs Catalysis. 8: 10190-10209. PMID 30450265 DOI: 10.1021/Acscatal.8B02509  0.537
2018 Zatolochnaya OV, Rodríguez S, Zhang Y, Lao KS, Tcyrulnikov S, Li G, Wang XJ, Qu B, Biswas S, Mangunuru HPR, Rivalti D, Sieber JD, Desrosiers JN, Leung JC, Grinberg N, et al. Copper-catalyzed asymmetric hydrogenation of 2-substituted ketones dynamic kinetic resolution. Chemical Science. 9: 4505-4510. PMID 29896393 DOI: 10.1039/C8Sc00434J  0.548
2018 Li G, Zatolochnaya OV, Wang XJ, Rodríguez S, Qu B, Desrosiers JN, Mangunuru HPR, Biswas S, Rivalti D, Karyakarte SD, Sieber JD, Grinberg N, Wu L, Lee H, Haddad N, et al. BABIPhos Family of Biaryl Dihydrobenzooxaphosphole Ligands for Asymmetric Hydrogenation. Organic Letters. PMID 29542928 DOI: 10.1021/Acs.Orglett.8B00139  0.531
2018 Qu B, Mangunuru HPR, Tcyrulnikov S, Rivalti D, Zatolochnaya OV, Kurouski D, Radomkit S, Biswas S, Karyakarte S, Fandrick KR, Sieber JD, Rodriguez S, Desrosiers JN, Haddad N, McKellop K, et al. Enantioselective Synthesis of α-(Hetero)aryl Piperidines through Asymmetric Hydrogenation of Pyridinium Salts and Its Mechanistic Insights. Organic Letters. PMID 29461064 DOI: 10.1021/Acs.Orglett.8B00067  0.523
2018 Sieber JD, Rodriguez S, Frutos R, Buono F, Zhang Y, Li N, Qu B, Premasiri A, Li Z, Han ZS, Xu Y, Byrne D, Haddad N, Lorenz J, Grinberg N, et al. Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF3-Alcohol Derivative in High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation. The Journal of Organic Chemistry. PMID 29323903 DOI: 10.1021/Acs.Joc.7B03022  0.629
2018 Zhang Y, Senanayake C, Lao K, Sieber J, Xu Y, Wu L, Wang X, Desrosiers J, Lee H, Haddad N, Han Z, Yee N, Song J, Howell A. Modular Dihydrobenzoazaphosphole Ligands for Suzuki–Miyaura Cross-Coupling Synthesis. 50: 4429-4434. DOI: 10.1055/S-0037-1610158  0.477
2017 Zhu RY, Saint-Denis TG, Shao Y, He J, Sieber JD, Senanayake CH, Yu JQ. Ligand-Enabled Pd(II)-Catalyzed Bromination and Iodination of C(sp3)-H Bonds. Journal of the American Chemical Society. PMID 28391681 DOI: 10.1021/Jacs.7B02196  0.441
2017 Haddad N, Mangunuru HPR, Fandrick KR, Qu B, Sieber JD, Rodriguez S, Desrosiers J-, Patel ND, Lee H, Kurouski D, Grinberg N, Yee NK, Song JJ, Senanayake CH. Ligand Effect on Diastereoselectivity in Suzuki–Miyaura Coupling Synfacts. 13: 168-168. DOI: 10.1055/S-0036-1589875  0.452
2017 Patel ND, Rivalti D, Buono FG, Chatterjee A, Qu B, Braith S, Desrosiers J, Rodriguez S, Sieber JD, Haddad N, Fandrick KR, Lee H, Yee NK, Busacca CA, Senanayake CH. Effective BI-DIME Ligand for Suzuki-Miyaura Cross-Coupling Reactions in Water with 500 ppm Palladium Loading and Triton X Asian Journal of Organic Chemistry. 6: 1285-1291. DOI: 10.1002/Ajoc.201700137  0.419
2016 Qu B, Mangunuru HP, Wei X, Fandrick KR, Desrosiers JN, Sieber JD, Kurouski D, Haddad N, Samankumara LP, Lee H, Savoie J, Ma S, Grinberg N, Sarvestani M, Yee NK, et al. Synthesis of Enantioenriched 2-Alkyl Piperidine Derivatives through Asymmetric Reduction of Pyridinium Salts. Organic Letters. PMID 27661252 DOI: 10.1021/Acs.Orglett.6B02401  0.579
2016 Qu B, Haddad N, Rodriguez S, Sieber JD, Desrosiers JN, Patel ND, Zhang Y, Grinberg N, Lee H, Ma S, Ries UJ, Yee NK, Senanayake CH. Ligand Accelerated Stereoretentive Suzuki-Miyaura Coupling of Unprotected 3,3'-Dibromo-BINOL. The Journal of Organic Chemistry. PMID 26756863 DOI: 10.1021/Acs.Joc.5B02368  0.629
2016 Sieber JD, Rivalti D, Herbage MA, Masters JT, Fandrick KR, Fandrick DR, Haddad N, Lee H, Yee NK, Gupton BF, Senanayake CH. Rh-catalysed asymmetric conjugate addition of boronic acids to nitroalkenes employing a: P -chiral P,π-hybrid ligand Organic Chemistry Frontiers. 3: 1149-1153. DOI: 10.1039/C6Qo00311G  0.552
2016 Haddad N, Mangunuru HPR, Fandrick KR, Qu B, Sieber JD, Rodriguez S, Desrosiers J, Patel ND, Lee H, Kurouski D, Grinberg N, Yee NK, Song JJ, Senanayake CH. Reengineered BI-DIME Ligand Core Based on Computer Modeling to Increase Selectivity in Asymmetric Suzuki-Miyaura Coupling for the Challenging Axially Chiral HIV Integrase Inhibitor Advanced Synthesis & Catalysis. 358: 3522-3527. DOI: 10.1002/Adsc.201600889  0.526
2016 Sieber JD, Angeles-Dunham VV, Chennamadhavuni D, Fandrick DR, Haddad N, Grinberg N, Kurouski D, Lee H, Song JJ, Yee NK, Mattson AE, Senanayake CH. Rhodium-Catalyzed Asymmetric Allenylation of Sulfonylimines and Application to the Stereospecific Allylic Allenylation Advanced Synthesis and Catalysis. 358: 3062-3068. DOI: 10.1002/Adsc.201600686  0.588
2015 Chen PH, Sieber J, Senanayake CH, Dong G. Rh-catalyzed Reagent-Free Ring Expansion of Cyclobutenones and Benzocyclobutenones. Chemical Science. 6: 5440-5445. PMID 28042458 DOI: 10.1039/C5Sc01875G  0.419
2015 Sieber JD, Qu B, Rodriguez S, Haddad N, Grinberg N, Lee H, Song JJ, Yee NK, Senanayake CH. Synthesis of P-Chiral Dihydrobenzooxaphospholes Through Negishi Cross-Coupling. The Journal of Organic Chemistry. PMID 26671422 DOI: 10.1021/Acs.Joc.5B02649  0.636
2015 Han ZS, Zhang L, Xu Y, Sieber JD, Marsini MA, Li Z, Reeves JT, Fandrick KR, Patel ND, Desrosiers JN, Qu B, Chen A, Rudzinski DM, Samankumara LP, Ma S, et al. Efficient asymmetric synthesis of structurally diverse P-stereogenic phosphinamides for catalyst design. Angewandte Chemie (International Ed. in English). 54: 5474-7. PMID 25757595 DOI: 10.1002/Anie.201500350  0.61
2015 Zeng X, Wei X, Song JJ, Sarvestani M, Fandrick DR, Qu B, Rodríguez S, Sieber JD, Desrosiers JN, Yee NK, Roschangar F, Senanayake CH. Development of a Practical Sequence for Difluoromethylation of 2-Bromopyridines via Copper-Mediated Reductive Coupling and Decarboxylation Asian Journal of Organic Chemistry. DOI: 10.1002/Ajoc.201500349  0.518
2014 Sieber JD, Chennamadhavuni D, Fandrick KR, Qu B, Han ZS, Savoie J, Ma S, Samankumara LP, Grinberg N, Lee H, Song JJ, Senanayake CH. Development of new P-chiral P,π-dihydrobenzooxaphosphole hybrid ligands for asymmetric catalysis. Organic Letters. 16: 5494-7. PMID 25298301 DOI: 10.1021/Ol5027798  0.456
2013 Han ZS, Herbage MA, Mangunuru HP, Xu Y, Zhang L, Reeves JT, Sieber JD, Li Z, DeCroos P, Zhang Y, Li G, Li N, Ma S, Grinberg N, Wang X, et al. Design and synthesis of chiral oxathiozinone scaffolds: efficient synthesis of hindered enantiopure sulfinamides and sulfinyl ketimines. Angewandte Chemie (International Ed. in English). 52: 6713-7. PMID 23677810 DOI: 10.1002/Anie.201301676  0.527
2013 Han ZS, Goyal N, Herbage MA, Sieber JD, Qu B, Xu Y, Li Z, Reeves JT, Desrosiers JN, Ma S, Grinberg N, Lee H, Mangunuru HP, Zhang Y, Krishnamurthy D, et al. Efficient asymmetric synthesis of P-chiral phosphine oxides via properly designed and activated benzoxazaphosphinine-2-oxide agents. Journal of the American Chemical Society. 135: 2474-7. PMID 23369026 DOI: 10.1021/Ja312352P  0.434
2012 Trost BM, Xie J, Sieber JD. ChemInform Abstract: The Palladium Catalyzed Asymmetric Addition of Oxindoles and Allenes: An Atom-Economical Versatile Method for the Construction of Chiral Indole Alkaloids. Cheminform. 43: no-no. DOI: 10.1002/chin.201220111  0.426
2011 Trost BM, Xie J, Sieber JD. The palladium catalyzed asymmetric addition of oxindoles and allenes: an atom-economical versatile method for the construction of chiral indole alkaloids. Journal of the American Chemical Society. 133: 20611-22. PMID 22070545 DOI: 10.1021/Ja209244M  0.515
2011 Brozek LA, Sieber JD, Morken JP. Catalytic enantioselective conjugate allylation of unsaturated methylidene ketones. Organic Letters. 13: 995-7. PMID 21288009 DOI: 10.1021/Ol102982B  0.815
2011 Brozek LA, Sieber JD, Morken JP. Catalytic Asymmetric Allylation of Unsaturated MethylideneKetones Synfacts. 2011: 626-626. DOI: 10.1055/S-0030-1260430  0.763
2010 Trost BM, Zhang T, Sieber JD. Catalytic asymmetric allylic alkylation employing heteroatom nucleophiles: A powerful method for C-X bond formation Chemical Science. 1: 427-440. DOI: 10.1039/C0Sc00234H  0.435
2009 Trost BM, Sieber JD, Qian W, Dhawan R, Ball ZT. Asymmetric total synthesis of soraphen A: a flexible alkyne strategy. Angewandte Chemie (International Ed. in English). 48: 5478-81. PMID 19554583 DOI: 10.1002/Anie.200901907  0.56
2009 Trost BM, Sieber JD, Qian W, Dhawan R, Ball ZT. ChemInform Abstract: Asymmetric Total Synthesis of Soraphen A: A Flexible Alkyne Strategy. Cheminform. 40. DOI: 10.1002/chin.200947206  0.436
2008 Sieber JD, Morken JP. Asymmetric Ni-catalyzed conjugate allylation of activated enones. Journal of the American Chemical Society. 130: 4978-83. PMID 18338891 DOI: 10.1021/Ja710922H  0.757
2007 Sieber JD, Liu S, Morken JP. Catalytic conjugate addition of allyl groups to styryl-activated enones. Journal of the American Chemical Society. 129: 2214-5. PMID 17266312 DOI: 10.1021/Ja067878W  0.72
2006 Sieber JD, Morken JP. Sequential Pd-catalyzed asymmetric allene diboration/alpha-aminoallylation. Journal of the American Chemical Society. 128: 74-5. PMID 16390128 DOI: 10.1021/Ja057020R  0.689
2006 Sieber JD, Morken JP. Sequential Pd-Catalyzed Asymmetric Allene Diboration/α-Aminoallylation Synfacts. 2006: 347-347. DOI: 10.1055/S-2006-934336  0.59
2004 Pelz NF, Woodward AR, Burks HE, Sieber JD, Morken JP. Palladium-catalyzed enantioselective diboration of prochiral allenes. Journal of the American Chemical Society. 126: 16328-9. PMID 15600327 DOI: 10.1021/Ja044167U  0.84
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