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Karyn McFadden, Ph.D. - Publications

Affiliations: 
Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
protein recognition, protein machine that controls HIV-1 cell entry into host cells
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Bastian AR, Ang CG, Kamanna K, Shaheen F, Huang YH, McFadden K, Duffy C, Bailey LD, Sundaram RV, Chaiken I. Targeting cell surface HIV-1 Env protein to suppress infectious virus formation. Virus Research. PMID 28390972 DOI: 10.1016/J.Virusres.2017.04.003  0.624
2013 Bastian AR, Contarino M, Bailey LD, Aneja R, Moreira DRM, Freedman K, McFadden K, Duffy C, Emileh A, Leslie G, Jacobson JM, Hoxie JA, Chaiken I. Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions Retrovirology. 10. PMID 24330857 DOI: 10.1186/1742-4690-10-153  0.698
2013 Contarino M, Bastian AR, Kalyana Sundaram RV, McFadden K, Duffy C, Gangupomu V, Baker M, Abrams C, Chaiken I. Chimeric Cyanovirin-MPER recombinantly engineered proteins cause cell-free virolysis of HIV-1. Antimicrobial Agents and Chemotherapy. 57: 4743-50. PMID 23856780 DOI: 10.1128/Aac.00309-13  0.661
2013 Kamanna K, Aneja R, Duffy C, Kubinski P, Rodrigo Moreira D, Bailey LD, McFadden K, Schön A, Holmes A, Tuzer F, Contarino M, Freire E, Chaiken IM. Non-natural peptide triazole antagonists of HIV-1 envelope gp120. Chemmedchem. 8: 322-8. PMID 23239505 DOI: 10.1002/Cmdc.201200422  0.679
2013 Tuzer F, Madani N, Kamanna K, Zentner I, LaLonde J, Holmes A, Upton E, Rajagopal S, McFadden K, Contarino M, Sodroski J, Chaiken I. HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism. Proteins. 81: 271-90. PMID 23011758 DOI: 10.1002/Prot.24184  0.746
2012 McFadden K, Fletcher P, Rossi F, Kantharaju, Umashankara M, Pirrone V, Rajagopal S, Gopi H, Krebs FC, Martin-Garcia J, Shattock RJ, Chaiken I. Antiviral breadth and combination potential of peptide triazole HIV-1 entry inhibitors. Antimicrobial Agents and Chemotherapy. 56: 1073-80. PMID 22083481 DOI: 10.1128/Aac.05555-11  0.744
2011 Ishino T, Economou NJ, McFadden K, Zaks-Zilberman M, Jost M, Baxter S, Contarino MR, Harrington AE, Loll PJ, Pasut G, Lievens S, Tavernier J, Chaiken I. A protein engineering approach differentiates the functional importance of carbohydrate moieties of interleukin-5 receptor α. Biochemistry. 50: 7546-56. PMID 21770429 DOI: 10.1021/Bi2009135  0.694
2011 Bastian AR, Kantharaju, McFadden K, Duffy C, Rajagopal S, Contarino MR, Papazoglou E, Chaiken I. Cell-free HIV-1 virucidal action by modified peptide triazole inhibitors of Env gp120. Chemmedchem. 6: 1335-9, 1318. PMID 21714095 DOI: 10.1002/Cmdc.201100177  0.736
2011 Gift SK, McFadden K, Zentner IJ, Rajagopal S, Zhang MY, Dimitrov DS, Chaiken IM. Monoclonal antibody m18 paratope leading to dual receptor antagonism of HIV-1 gp120. Biochemistry. 50: 2769-79. PMID 21417283 DOI: 10.1021/Bi101161J  0.75
2011 Gift SK, Zentner IJ, Schön A, McFadden K, Umashankara M, Rajagopal S, Contarino M, Duffy C, Courter JR, Zhang MY, Gershoni JM, Cocklin S, Dimitrov DS, Smith AB, Freire E, et al. Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18. Biochemistry. 50: 2756-68. PMID 21351734 DOI: 10.1021/Bi101160R  0.748
2011 Bastian AR, Kantharaju, McFadden K, Duffy C, Rajagopal S, Contarino MR, Papazoglou E, Chaiken I. Inside Cover: Cell‐Free HIV‐1 Virucidal Action by Modified Peptide Triazole Inhibitors of Env gp120 (ChemMedChem 8/2011) Chemmedchem. 6: 1318-1318. DOI: 10.1002/Cmdc.201190033  0.599
2010 Umashankara M, McFadden K, Zentner I, Schön A, Rajagopal S, Tuzer F, Kuriakose SA, Contarino M, Lalonde J, Freire E, Chaiken I. The active core in a triazole peptide dual-site antagonist of HIV-1 gp120 Chemmedchem. 5: 1871-1879. PMID 20677318 DOI: 10.1002/Cmdc.201000222  0.701
2009 Gopi H, Cocklin S, Pirrone V, McFadden K, Tuzer F, Zentner I, Ajith S, Baxter S, Jawanda N, Krebs FC, Chaiken IM. Introducing metallocene into a triazole peptide conjugate reduces its off-rate and enhances its affinity and antiviral potency for HIV-1 gp120. Journal of Molecular Recognition : Jmr. 22: 169-74. PMID 18498083 DOI: 10.1002/Jmr.892  0.795
2007 McFadden K, Cocklin S, Gopi H, Baxter S, Ajith S, Mahmood N, Shattock R, Chaiken I. A recombinant allosteric lectin antagonist of HIV-1 envelope gp120 interactions. Proteins. 67: 617-29. PMID 17348010 DOI: 10.1002/Prot.21295  0.778
2005 Colleluori DM, Tien D, Kang F, Pagliei T, Kuss R, McCormick T, Watson K, McFadden K, Chaiken I, Buckheit RW, Romano JW. Expression, purification, and characterization of recombinant cyanovirin-N for vaginal anti-HIV microbicide development. Protein Expression and Purification. 39: 229-36. PMID 15642474 DOI: 10.1016/J.Pep.2004.10.009  0.604
1998 Feng Y, Chung D, Garrard L, McEnroe G, Lim D, Scardina J, McFadden K, Guzzetta A, Lam A, Abraham J, Liu D, Endemann G. Peptides derived from the complementarity-determining regions of anti-Mac-1 antibodies block intercellular adhesion molecule-1 interaction with Mac-1. The Journal of Biological Chemistry. 273: 5625-30. PMID 9488691 DOI: 10.1074/Jbc.273.10.5625  0.305
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