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Kenneth P. Mackie - Publications

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Cannabinoid receptors and signaling
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Year Citation  Score
2021 Tortoriello G, Beiersdorf J, Romani S, Williams G, Cameron GA, Mackie K, Williams MJ, Di Marzo V, Keimpema E, Doherty P, Harkany T. Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in . Cannabis and Cannabinoid Research. 6: 119-136. PMID 33912677 DOI: 10.1089/can.2020.0010  0.364
2021 Kolbe MR, Hohmann T, Hohmann U, Ghadban C, Mackie K, Zöller C, Prell J, Illert J, Strauss C, Dehghani F. THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner. Cancers. 13. PMID 33802282 DOI: 10.3390/cancers13051064  0.367
2021 Cottone E, Pomatto V, Rapelli S, Scandiffio R, Mackie K, Bovolin P. Cannabinoid Receptor Modulation of Neurogenesis: ST14A Striatal Neural Progenitor Cells as a Simplified In Vitro Model. Molecules (Basel, Switzerland). 26. PMID 33800024 DOI: 10.3390/molecules26051448  0.327
2021 Dvorakova M, Kubik-Zahorodna A, Straiker A, Sedlacek R, Hajkova A, Mackie K, Blahos J. SGIP1 is involved in regulation of emotionality, mood, and nociception and tunes in vivo signaling of Cannabinoid Receptor 1. British Journal of Pharmacology. PMID 33491188 DOI: 10.1111/bph.15383  0.805
2020 Lu HC, Mackie K. Review of the Endocannabinoid System. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 32980261 DOI: 10.1016/j.bpsc.2020.07.016  0.418
2020 Iyer V, Slivicki RA, Thomaz AC, Crystal JD, Mackie K, Hohmann AG. The cannabinoid CB receptor agonist LY2828360 synergizes with morphine to suppress neuropathic nociception and attenuates morphine reward and physical dependence. European Journal of Pharmacology. 886: 173544. PMID 32896549 DOI: 10.1016/J.Ejphar.2020.173544  0.314
2020 Martinez LR, Black KC, Webb BT, Bell A, Baygani SK, Mier TJ, Dominguez L, Mackie K, Kalinovsky A. Components of Endocannabinoid Signaling System are Expressed in the Perinatal Mouse Cerebellum and Required for its Normal Development. Eneuro. PMID 32179579 DOI: 10.1523/ENEURO.0471-19.2020  0.356
2020 Farkas E, Varga E, Kovács B, Szilvásy-Szabó A, Cote-Vélez A, Péterfi Z, Matziari M, Tóth M, Zelena D, Mezriczky Z, Kádár A, Kővári D, Watanabe M, Kano M, Mackie K, et al. A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System. Iscience. 23: 100921. PMID 32143135 DOI: 10.1016/J.Isci.2020.100921  0.344
2020 Marcus DJ, Bedse G, Gaulden AD, Ryan JD, Kondev V, Winters ND, Rosas-Vidal LE, Altemus M, Mackie K, Lee FS, Delpire E, Patel S. Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening. Neuron. PMID 31948734 DOI: 10.1016/J.Neuron.2019.12.024  0.317
2019 Zuccarini G, D’Atri I, Cottone E, Mackie K, Shainer I, Gothilf Y, Provero P, Bovolin P, Merlo GR. Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos. International Journal of Molecular Sciences. 21: 168. PMID 31881740 DOI: 10.3390/Ijms21010168  0.403
2019 Henderson-Redmond AN, Nealon CM, Davis BJ, Yuill MB, Sepulveda DE, Blanton H, Piscura MK, Zee ML, Haskins CP, Marcus DJ, Mackie K, Guindon J, Morgan DJ. c-Jun N terminal kinase signaling pathways mediate cannabinoid tolerance in an agonist-specific manner. Neuropharmacology. 107847. PMID 31758947 DOI: 10.1016/j.neuropharm.2019.107847  0.512
2019 Garai S, Kulkarni PM, Schaffer PC, Leo L, Brandt AL, Zagzoog A, Black T, Lin X, Hurst DP, Janero DR, Abood ME, Zimmowitch A, Straiker A, Pertwee RG, Kelly M, ... ... Mackie K, et al. Application of Fluorine- And Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of CB1 Receptor Positive Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31756109 DOI: 10.1021/Acs.Jmedchem.9B01142  0.798
2019 Cinquina V, Calvigioni D, Farlik M, Halbritter F, Fife-Gernedl V, Shirran SL, Fuszard MA, Botting CH, Poullet P, Piscitelli F, Máté Z, Szabó G, Yanagawa Y, Kasper S, Di Marzo V, ... Mackie K, et al. Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy. Molecular Psychiatry. PMID 31735910 DOI: 10.1038/S41380-019-0580-4  0.367
2019 Jacobs IR, Xu C, Hermes DJ, League AF, Xu C, Nath B, Jiang W, Niphakis MJ, Cravatt BF, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Inhibitory Control Deficits Associated with Upregulation of CBR in the HIV-1 Tat Transgenic Mouse Model of Hand. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 31372820 DOI: 10.1007/S11481-019-09867-W  0.318
2019 Pickel VM, Bourie F, Chan J, Mackie K, Lane D, Wang G. Chronic adolescent exposure to ∆9-tetrahydrocannabinol decreases NMDA current and extrasynaptic plasmalemmal density of NMDA GluN1 subunits in the prelimbic cortex of adult male mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31323660 DOI: 10.1038/s41386-019-0466-9  0.386
2019 Wang ZJ, Hu SS, Bradshaw HB, Sun L, Mackie K, Straiker A, Heinbockel T. Cannabinoid Receptor-Mediated Modulation of Inhibitory Inputs to Mitral Cells in the Main Olfactory Bulb. Journal of Neurophysiology. PMID 31215302 DOI: 10.1152/Jn.00100.2018  0.813
2019 Leishman E, Mackie K, Bradshaw HB. Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype. Frontiers in Molecular Neuroscience. 12: 142. PMID 31213981 DOI: 10.3389/fnmol.2019.00142  0.304
2019 Urquhart MA, Ross JA, Reyes BAS, Nitikman M, Thomas SA, Mackie K, Van Bockstaele EJ. Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex. Neurobiology of Stress. 10: 100164. PMID 31193575 DOI: 10.1016/j.ynstr.2019.100164  0.319
2019 Smoker MP, Mackie K, Lapish CC, Boehm SL. Self-administration of edible Δ-tetrahydrocannabinol and associated behavioral effects in mice. Drug and Alcohol Dependence. 199: 106-115. PMID 31029878 DOI: 10.1016/J.Drugalcdep.2019.02.020  0.303
2019 Fitzgerald ML, Mackie K, Pickel VM. Ultrastructural localization of cannabinoid-1 (CB1) and mGluR5 receptors in the prefrontal cortex and amygdala. The Journal of Comparative Neurology. PMID 31008528 DOI: 10.1002/Cne.24704  0.4
2019 Murataeva N, Daily L, Taylor X, Dhopeshwarkar A, Hu SS, Miller S, McHugh D, Oehler O, Li S, Bonanno JA, Mackie K, Straiker A. Evidence for a GPR18 Role in Chemotaxis, Proliferation, and the Course of Wound Closure in the Cornea. Cornea. PMID 30969262 DOI: 10.1097/Ico.0000000000001934  0.794
2019 Grabiec U, Hohmann T, Ghadban C, Rothgänger C, Wong D, Antonietti A, Groth T, Mackie K, Dehghani F. Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures. International Journal of Molecular Sciences. 20. PMID 30871175 DOI: 10.3390/ijms20061266  0.48
2019 Korchynska S, Lutz MI, Borók E, Pammer J, Cinquina V, Fedirko N, Irving AJ, Mackie K, Harkany T, Keimpema E. GPR55 controls functional differentiation of self-renewing epithelial progenitors for salivation. Jci Insight. 4. PMID 30830860 DOI: 10.1172/Jci.Insight.122947  0.358
2019 Hawken ER, Normandeau CP, Gardner Gregory J, Cécyre B, Bouchard JF, Mackie K, Dumont ÉC. A novel GPR55-mediated satiety signal in the oval Bed Nucleus of the Stria Terminalis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30647449 DOI: 10.1038/S41386-018-0309-0  0.342
2019 Mackie K, Ford C, Stella N. Decision letter: Cocaine-induced endocannabinoid signaling mediated by sigma-1 receptors and extracellular vesicle secretion Elife. DOI: 10.7554/Elife.47209.021  0.373
2019 Abood M, Alexander SP, Barth F, Bonner TI, Bradshaw H, Cabral G, Casellas P, Cravatt BF, Devane WA, Di Marzo V, Elphick MR, Felder CC, Greasley P, Herkenham M, Howlett AC, ... ... Mackie K, et al. Cannabinoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f13/2019.4  0.38
2018 Leishman E, Murphy MN, Murphy MI, Mackie K, Bradshaw HB. Broad and Region-Specific Impacts of the Synthetic Cannabinoid CP 55,940 in Adolescent and Adult Female Mouse Brains. Frontiers in Molecular Neuroscience. 11: 436. PMID 30542263 DOI: 10.3389/fnmol.2018.00436  0.32
2018 Li AL, Lin X, Dhopeshwarkar AS, Thomaz AC, Carey LM, Liu Y, Nikas SP, Makriyannis A, Mackie K, Hohmann AG. The cannabinoid CB2 agonist AM1710 differentially suppresses distinct pathological pain states and attenuates morphine tolerance and withdrawal. Molecular Pharmacology. PMID 30504240 DOI: 10.1124/Mol.118.113233  0.396
2018 Chen YH, Lee HJ, Lee MT, Wu YT, Lee YH, Hwang LL, Hung MS, Zimmer A, Mackie K, Chiou LC. Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray. Proceedings of the National Academy of Sciences of the United States of America. PMID 30348772 DOI: 10.1073/pnas.1807991115  0.372
2018 Bara A, Manduca A, Bernabeu A, Borsoi M, Serviado M, Lassalle O, Murphy MN, Wager-Miller J, Mackie K, Pelissier-Alicot AL, Trezza V, Manzoni OJ. Sex-dependent effects of in utero cannabinoid exposure on cortical function. Elife. 7. PMID 30201092 DOI: 10.7554/Elife.36234  0.335
2018 Liu Y, Ji L, Eno M, Kudalkar S, Li A, Schimpgen M, Benchama O, Morales P, Xu S, Hurst DP, Wu S, Mohammad KA, Wood JT, Zvonok N, Papahatjis D, ... ... Mackie K, et al. (R)-N-(1-Methyl-2-hydroxyethyl)-13-(S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. Journal of Medicinal Chemistry. PMID 30196704 DOI: 10.1021/Acs.Jmedchem.8B00611  0.314
2018 Hermes DJ, Xu C, Poklis JL, Niphakis MJ, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS. Neuropharmacology. PMID 30114402 DOI: 10.1016/J.Neuropharm.2018.08.013  0.443
2018 Mulpuri Y, Marty VN, Munier JJ, Mackie K, Schmidt BL, Seltzman HH, Spigelman I. Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation. Neuropharmacology. PMID 29981335 DOI: 10.1016/J.Neuropharm.2018.07.002  0.348
2018 Migliaccio M, Ricci G, Suglia A, Manfrevola F, Mackie K, Fasano S, Pierantoni R, Chioccarelli T, Cobellis G. Analysis of Endocannabinoid System in Rat Testis During the First Spermatogenetic Wave. Frontiers in Endocrinology. 9: 269. PMID 29896156 DOI: 10.3389/Fendo.2018.00269  0.439
2018 Miller S, Kulkarni S, Ciesielski A, Nikas SP, Mackie K, Makriyannis A, Straiker A. Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure. Pharmaceuticals (Basel, Switzerland). 11. PMID 29786643 DOI: 10.3390/Ph11020050  0.813
2018 Straiker A, Dvorakova M, Zimmowitch A, Mackie KP. Cannabidiol inhibits endocannabinoid signaling in autaptic hippocampal neurons. Molecular Pharmacology. PMID 29669714 DOI: 10.1124/mol.118.111864  0.833
2018 Leishman E, Murphy M, Mackie K, Bradshaw HB. Δ9-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult. Biochimica Et Biophysica Acta. 1863: 479-492. PMID 29408467 DOI: 10.1016/j.bbalip.2018.02.001  0.302
2017 Shonesy BC, Parrish WP, Haddad HK, Stephenson JR, Báldi R, Bluett RJ, Marks CR, Centanni SW, Folkes OM, Spiess K, Augustin SM, Mackie K, Lovinger DM, Winder DG, Patel S, et al. Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior. Biological Psychiatry. PMID 29458998 DOI: 10.1016/J.Biopsych.2017.11.036  0.535
2017 Sumida H, Lu E, Chen H, Yang Q, Mackie K, Cyster JG. GPR55 regulates intraepithelial lymphocyte migration dynamics and susceptibility to intestinal damage. Science Immunology. 2. PMID 29222090 DOI: 10.1126/Sciimmunol.Aao1135  0.394
2017 Sepers MD, Smith-Dijak A, LeDue J, Kolodziejczyk K, Mackie K, Raymond LA. Endocannabinoid-specific impairment in synaptic plasticity in striatum of Huntington's disease mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29192125 DOI: 10.1523/JNEUROSCI.1739-17.2017  0.361
2017 Lin X, Dhopeshwarkar AS, Huibregtse M, Mackie K, Hohmann AG. The slowly signaling G protein-biased CB2 cannabinoid receptor agonist LY2828360 suppresses neuropathic pain with sustained efficacy and attenuates morphine tolerance and dependence. Molecular Pharmacology. PMID 29192123 DOI: 10.1124/Mol.117.109355  0.319
2017 Westphal M, Schafroth MA, Sarott R, Imhof M, Bold C, Leippe P, Dhopeshwarkar A, Grandner J, Katritch V, Mackie K, Trauner D, Carreira EM, Frank JA. Synthesis of Photoswitchable Δ(9)-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling. Journal of the American Chemical Society. PMID 29161035 DOI: 10.1021/Jacs.7B06456  0.466
2017 Mitjavila J, Yin D, Kulkarni PM, Zanato C, Thakur GA, Ross R, Greig I, Mackie K, Straiker A. Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons. Pharmacological Research. PMID 29158048 DOI: 10.1016/j.phrs.2017.11.019  0.823
2017 Jourdan T, Park JK, Varga ZV, Pálóczi J, Coffey NJ, Rosenberg AZ, Godlewski G, Cinar R, Mackie K, Pacher P, Kunos G. Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy. Diabetes, Obesity & Metabolism. PMID 29106063 DOI: 10.1111/Dom.13150  0.344
2017 Slivicki RA, Xu Z, Kulkarni PM, Pertwee RG, Mackie K, Thakur GA, Hohmann AG. Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence. Biological Psychiatry. PMID 28823711 DOI: 10.1016/J.Biopsych.2017.06.032  0.402
2017 Xu C, Hermes DJ, Nwanguma B, Jacobs IR, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska B, Fitting S. Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein. Molecular and Cellular Neurosciences. PMID 28733129 DOI: 10.1016/J.Mcn.2017.07.003  0.383
2017 Ruehle S, Wager-Miller J, Straiker A, Farnsworth J, Murphy MN, Loch S, Monory K, Mackie K, Lutz B. Discovery and characterization of two novel CB1 receptor splice variants with modified N-termini in mouse. Journal of Neurochemistry. PMID 28608535 DOI: 10.1111/jnc.14099  0.825
2017 Miller S, Hu SS, Leishman E, Morgan D, Wager-Miller J, Mackie K, Bradshaw HB, Straiker A. A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner. Investigative Ophthalmology & Visual Science. 58: 2930-2938. PMID 28593245 DOI: 10.1167/iovs.16-21330  0.793
2017 Li AL, Carey LM, Mackie K, Hohmann AG. The cannabinoid CB2 agonist GW405833 suppresses inflammatory and neuropathic pain through a CB1 mechanism that is independent of CB2 receptors in mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 28592614 DOI: 10.1124/Jpet.117.241901  0.382
2017 Khurana L, Mackie K, Piomelli D, Kendall DA. Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology. PMID 28527758 DOI: 10.1016/J.Neuropharm.2017.05.018  0.609
2017 Zhong H, Tong L, Gu N, Gao F, Lu Y, Xie RG, Liu J, Li X, Bergeron R, Pomeranz LE, Mackie K, Wang F, Luo CX, Ren Y, Wu SX, et al. Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice. The Journal of Clinical Investigation. PMID 28463228 DOI: 10.1172/JCI91038  0.377
2017 Carey LM, Gutierrez T, Deng L, Lee WH, Mackie K, Hohmann AG. Inflammatory and Neuropathic Nociception is Preserved in GPR55 Knockout Mice. Scientific Reports. 7: 944. PMID 28428628 DOI: 10.1038/s41598-017-01062-2  0.318
2017 Marcus DJ, Henderson-Redmond AN, Gonek M, Zee ML, Farnsworth JC, Amin RA, Andrews MJ, Davis BJ, Mackie K, Morgan DJ. Mice expressing a "hyper-sensitive" form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption. Plos One. 12: e0174826. PMID 28426670 DOI: 10.1371/journal.pone.0174826  0.442
2017 Cinar R, Gochuico BR, Iyer MR, Jourdan T, Yokoyama T, Park JK, Coffey NJ, Pri-Chen H, Szanda G, Liu Z, Mackie K, Gahl WA, Kunos G. Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis. Jci Insight. 2. PMID 28422760 DOI: 10.1172/jci.insight.92281  0.318
2016 Sousa-Valente J, Varga A, Torres Perez JV, Jenes A, Wahba J, Mackie K, Cravatt B, Ueda N, Tsuboi K, Santha P, Jancso G, Tailor H, Avelino A, Nagy I. Inflammation of peripheral tissues and injury to peripheral nerves induce diferring effects in the expression of the calcium-sensitive anandamide-synthesising enzyme and related molecules in rat primary sensory neurons. The Journal of Comparative Neurology. PMID 27997038 DOI: 10.1002/Cne.24154  0.469
2016 Dhopeshwarkar A, Murataeva N, Makriyannis A, Straiker A, Mackie KP. Two Janus cannabinoids that are both CB2 agonists and CB1 antagonists. The Journal of Pharmacology and Experimental Therapeutics. PMID 27927913 DOI: 10.1124/Jpet.116.236539  0.833
2016 Fung S, Xu C, Hamel E, Wager-Miller JB, Woodruff G, Miller A, Sanford C, Mackie K, Stella N. Novel indole-based compounds that differentiate alkylindole-sensitive receptors from cannabinoid receptors and microtubules: Characterization of their activity on glioma cell migration. Pharmacological Research. PMID 27832960 DOI: 10.1016/j.phrs.2016.10.025  0.482
2016 Chen J, Varga A, Selvarajah S, Jenes A, Dienes B, Sousa-Valente J, Kulik A, Veress G, Brain SD, Baker D, Urban L, Mackie K, Nagy I. Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk. Scientific Reports. 6: 33307. PMID 27653550 DOI: 10.1038/Srep33307  0.503
2016 Wang W, Trieu BH, Palmer LC, Jia Y, Pham DT, Jung KM, Karsten CA, Merrill CB, Mackie K, Gall CM, Piomelli D, Lynch G. A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation. Eneuro. 3. PMID 27517090 DOI: 10.1523/ENEURO.0160-16.2016  0.513
2016 Marcus DJ, Zee ML, Davis BJ, Haskins CP, Andrews MJ, Amin R, Henderson-Redmond AN, Mackie K, Czyzyk TA, Morgan DJ. Mice Expressing a "Hyper-Sensitive" Form of the Cannabinoid Receptor 1 (CB1) Are Neither Obese Nor Diabetic. Plos One. 11: e0160462. PMID 27501235 DOI: 10.1371/Journal.Pone.0160462  0.746
2016 Tung LW, Lu GL, Lee YH, Yu L, Lee HJ, Leishman E, Bradshaw H, Hwang LL, Hung MS, Mackie K, Zimmer A, Chiou LC. Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons. Nature Communications. 7: 12199. PMID 27448020 DOI: 10.1038/ncomms12199  0.382
2016 Wager-Miller J, Mackie K. Quantitation of Plasma Membrane (G Protein-Coupled) Receptor Trafficking in Cultured Cells Methods of Molecular Biology. 1412: 255-266. PMID 27245911 DOI: 10.1007/978-1-4939-3539-0_26  0.442
2016 Wager-Miller J, Mackie K. Western Blotting of the Endocannabinoid System Methods of Molecular Biology. 1412: 247-254. PMID 27245910 DOI: 10.1007/978-1-4939-3539-0_25  0.399
2016 Pinheiro BS, Lemos C, Neutzling-Kaufmann F, Marques JM, da Silva-Santos CS, Carvalho E, Mackie K, Rodrigues RJ, Cunha RA, Köfalvi A. Hierarchical glucocorticoid-endocannabinoid interplay regulates the activation of the nucleus accumbens by insulin. Brain Research Bulletin. PMID 27208730 DOI: 10.1016/j.brainresbull.2016.05.009  0.311
2016 Dhopeshwarkar A, Mackie K. Functional Selectivity of CB2 Cannabinoid Receptor Ligands at a Canonical and Noncanonical Pathway. Journal of Pharmacology and Experimental Therapeutics. 358: 342-351. PMID 27194477 DOI: 10.1124/Jpet.116.232561  0.418
2016 Carey LM, Slivicki RA, Leishman E, Cornett B, Mackie K, Bradshaw H, Hohmann AG. A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase. Molecular Pain. 12. PMID 27178246 DOI: 10.1177/1744806916649192  0.382
2016 Murataeva N, Dhopeshwarkar A, Yin D, Mitjavila J, Bradshaw H, Straiker A, Mackie K. WHERE's MY ENTOURAGE? THE CURIOUS CASE OF 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol. Pharmacological Research. PMID 27117667 DOI: 10.1016/J.Phrs.2016.04.015  0.817
2016 Leishman E, Cornett B, Spork K, Straiker A, Mackie K, Bradshaw HB. Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain. Pharmacological Research. PMID 27109320 DOI: 10.1016/j.phrs.2016.04.020  0.765
2016 Delgado-Peraza F, Ahn K, Nogueras-Ortiz C, Mungrue I, Mackie KP, Kendall DA, Yudowski G. Mechanisms of biased beta-arrestin mediated signaling downstream from the cannabinoid 1 receptor. Molecular Pharmacology. PMID 27009233 DOI: 10.1124/Mol.115.103176  0.327
2016 Wang Y, Gu N, Duan T, Kesner P, Blaskovits F, Liu J, Lu Y, Tong L, Gao F, Harris C, Mackie K, Li J, Tan Q, Hill MN, Yuan Z, et al. Monoacylglycerol lipase inhibitors produce pro- or antidepressant responses via hippocampal CA1 GABAergic synapses. Molecular Psychiatry. PMID 27001616 DOI: 10.1038/Mp.2016.22  0.348
2016 Xu C, Hermes DJ, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 26993829 DOI: 10.1007/S11481-016-9664-Y  0.34
2016 Lee HJ, Chang LY, Ho YC, Teng SF, Hwang LL, Mackie K, Chiou LC. Stress induces analgesia via orexin 1 receptor-initiated endocannabinoid/CB1 signaling in the mouse periaqueductal gray. Neuropharmacology. PMID 26907809 DOI: 10.1016/j.neuropharm.2016.02.018  0.472
2015 Lu HC, Mackie K. An Introduction to the Endogenous Cannabinoid System. Biological Psychiatry. PMID 26698193 DOI: 10.1016/j.biopsych.2015.07.028  0.51
2015 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Björklund P, Mackie K, Di Marzo V, Hökfelt TG, Dobrzyn A, Harkany T. Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proceedings of the National Academy of Sciences of the United States of America. PMID 26494286 DOI: 10.1073/Pnas.1519040112  0.347
2015 Hu SS, Mackie K. Distribution of the Endocannabinoid System in the Central Nervous System. Handbook of Experimental Pharmacology. 231: 59-93. PMID 26408158 DOI: 10.1007/978-3-319-20825-1_3  0.583
2015 Straiker A, Mitjavila J, Yin D, Gibson A, Mackie K. Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model. Pharmacological Research. 99: 370-6. PMID 26211948 DOI: 10.1016/j.phrs.2015.07.017  0.815
2015 Reyes BA, Heldt NA, Mackie K, Van Bockstaele EJ. Ultrastructural evidence for synaptic contacts between cortical noradrenergic afferents and endocannabinoid-synthesizing post-synaptic neurons. Neuroscience. 303: 323-37. PMID 26162236 DOI: 10.1016/j.neuroscience.2015.07.009  0.395
2015 Marcus DJ, Zee M, Hughes A, Yuill MB, Hohmann AG, Mackie K, Guindon J, Morgan DJ. Tolerance to the antinociceptive effects of chronic morphine requires c-Jun N-terminal kinase. Molecular Pain. 11: 34. PMID 26065412 DOI: 10.1186/s12990-015-0031-4  0.461
2015 Murataeva N, Li S, Oehler O, Miller S, Dhopeshwarkar A, Hu SS, Bonanno JA, Bradshaw H, Mackie K, McHugh D, Straiker A. Cannabinoid-induced chemotaxis in bovine corneal epithelial cells. Investigative Ophthalmology & Visual Science. 56: 3304-13. PMID 26024113 DOI: 10.1167/Iovs.14-15675  0.811
2015 Janero DR, Yaddanapudi S, Zvonok N, Subramanian KV, Shukla VG, Stahl E, Zhou L, Hurst D, Wager-Miller J, Bohn LM, Reggio PH, Mackie K, Makriyannis A. Molecular-Interaction and Signaling Profiles of AM3677, a Novel Covalent Agonist Selective for the Cannabinoid 1 Receptor. Acs Chemical Neuroscience. PMID 25978068 DOI: 10.1021/Acschemneuro.5B00090  0.462
2015 Deng L, Cornett BL, Mackie K, Hohmann AG. CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain. Molecular Pharmacology. 88: 64-74. PMID 25904556 DOI: 10.1124/mol.115.098483  0.417
2015 Bashashati M, Nasser Y, Keenan CM, Ho W, Piscitelli F, Nalli M, Mackie K, Storr MA, Di Marzo V, Sharkey KA. Inhibiting endocannabinoid biosynthesis: a novel approach to the treatment of constipation. British Journal of Pharmacology. 172: 3099-111. PMID 25684407 DOI: 10.1111/Bph.13114  0.506
2015 Smith TH, Blume LC, Straiker A, Cox JO, David BG, McVoy JR, Sayers KW, Poklis JL, Abdullah RA, Egertová M, Chen CK, Mackie K, Elphick MR, Howlett AC, Selley DE. Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation. Molecular Pharmacology. 87: 747-65. PMID 25657338 DOI: 10.1124/Mol.114.096495  0.823
2015 Mukhopadhyay B, Schuebel K, Mukhopadhyay P, Cinar R, Godlewski G, Xiong K, Mackie K, Lizak M, Yuan Q, Goldman D, Kunos G. Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms. Hepatology (Baltimore, Md.). 61: 1615-26. PMID 25580584 DOI: 10.1002/Hep.27686  0.318
2015 Keenan CM, Storr MA, Thakur GA, Wood JT, Wager-Miller J, Straiker A, Eno MR, Nikas SP, Bashashati M, Hu H, Mackie K, Makriyannis A, Sharkey KA. AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner. British Journal of Pharmacology. 172: 2406-18. PMID 25572435 DOI: 10.1111/Bph.13069  0.796
2015 Deng L, Guindon J, Cornett BL, Makriyannis A, Mackie K, Hohmann AG. Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal. Biological Psychiatry. 77: 475-87. PMID 24853387 DOI: 10.1016/j.biopsych.2014.04.009  0.502
2015 Straiker A, Mitjavila J, Yin D, Gibson A, Mackie K. Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model Pharmacological Research. 99: 370-376. DOI: 10.1016/j.phrs.2015.07.017  0.749
2014 Maccarrone M, Guzmán M, Mackie K, Doherty P, Harkany T. Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. Nature Reviews. Neuroscience. 15: 786-801. PMID 25409697 DOI: 10.1038/Nrn3846  0.361
2014 Melis M, Sagheddu C, De Felice M, Casti A, Madeddu C, Spiga S, Muntoni AL, Mackie K, Marsicano G, Colombo G, Castelli MP, Pistis M. Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12716-24. PMID 25232109 DOI: 10.1523/Jneurosci.1844-14.2014  0.32
2014 Cathel AM, Reyes BA, Wang Q, Palma J, Mackie K, Van Bockstaele EJ, Kirby LG. Cannabinoid modulation of alpha2 adrenergic receptor function in rodent medial prefrontal cortex. The European Journal of Neuroscience. 40: 3202-14. PMID 25131562 DOI: 10.1111/ejn.12690  0.422
2014 Dhopeshwarkar A, Mackie K. CB2cannabinoid receptors as a therapeutic target-what does the future hold? Molecular Pharmacology. 86: 430-437. PMID 25106425 DOI: 10.1124/Mol.114.094649  0.481
2014 Flores-Otero J, Ahn KH, Delgado-Peraza F, Mackie K, Kendall DA, Yudowski GA. Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1. Nature Communications. 5: 4589. PMID 25081814 DOI: 10.1038/Ncomms5589  0.447
2014 Wu CS, Morgan D, Jew CP, Haskins C, Andrews MJ, Leishman E, Spencer CM, Czyzyk T, Bradshaw H, Mackie K, Lu HC. Long-term consequences of perinatal fatty acid amino hydrolase inhibition. British Journal of Pharmacology. 171: 1420-34. PMID 24730060 DOI: 10.1111/Bph.12500  0.722
2014 Morgan DJ, Davis BJ, Kearn CS, Marcus D, Cook AJ, Wager-Miller J, Straiker A, Myoga MH, Karduck J, Leishman E, Sim-Selley LJ, Czyzyk TA, Bradshaw HB, Selley DE, Mackie K. Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5152-63. PMID 24719095 DOI: 10.1523/Jneurosci.3445-12.2014  0.816
2014 Ramikie TS, Nyilas R, Bluett RJ, Gamble-George JC, Hartley ND, Mackie K, Watanabe M, Katona I, Patel S. Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses. Neuron. 81: 1111-25. PMID 24607231 DOI: 10.1016/J.Neuron.2014.01.012  0.352
2014 Hernández-Castellanos JM, Vivas O, Garduño J, De la Cruz L, Arenas I, Elías-Viñas D, Mackie K, García DE. Gβ₂ mimics activation kinetic slowing of CaV2.2 channels by noradrenaline in rat sympathetic neurons. Biochemical and Biophysical Research Communications. 445: 250-4. PMID 24513289 DOI: 10.1016/j.bbrc.2014.01.192  0.74
2014 Lovelace JW, Vieira PA, Corches A, Mackie K, Korzus E. Impaired fear memory specificity associated with deficient endocannabinoid-dependent long-term plasticity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1685-93. PMID 24457285 DOI: 10.1038/Npp.2014.15  0.342
2014 Murataeva N, Straiker A, Mackie K. Parsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNS. British Journal of Pharmacology. 171: 1379-91. PMID 24102242 DOI: 10.1111/Bph.12411  0.78
2014 Bashashati M, Ho W, Mackie K, Hollenberg MD, Sharkey KA. Sa2055 Alpha/Beta Hydrolase Domain 6 (ABHD6), A Novel Endocannabinoid Hydrolytic Enzyme, Regulates Contractility in the Mouse Intestine Gastroenterology. 146: S-365. DOI: 10.1016/S0016-5085(14)61322-6  0.461
2013 Cluny NL, Baraboi ED, Mackie K, Burdyga G, Richard D, Dockray GJ, Sharkey KA. High fat diet and body weight have different effects on cannabinoid CB(1) receptor expression in rat nodose ganglia. Autonomic Neuroscience : Basic & Clinical. 179: 122-30. PMID 24145047 DOI: 10.1016/J.Autneu.2013.09.015  0.456
2013 Petrov RR, Knight L, Chen SR, Wager-Miller J, McDaniel SW, Diaz F, Barth F, Pan HL, Mackie K, Cavasotto CN, Diaz P. Mastering tricyclic ring systems for desirable functional cannabinoid activity. European Journal of Medicinal Chemistry. 69: 881-907. PMID 24125850 DOI: 10.1016/j.ejmech.2013.09.038  0.439
2013 Malenczyk K, Jazurek M, Keimpema E, Silvestri C, Janikiewicz J, Mackie K, Di Marzo V, Redowicz MJ, Harkany T, Dobrzyn A. CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. The Journal of Biological Chemistry. 288: 32685-99. PMID 24089517 DOI: 10.1074/Jbc.M113.478354  0.363
2013 Garzón M, Duffy AM, Chan J, Lynch MK, Mackie K, Pickel VM. Dopamine D₂ and acetylcholine α7 nicotinic receptors have subcellular distributions favoring mediation of convergent signaling in the mouse ventral tegmental area. Neuroscience. 252: 126-43. PMID 23954803 DOI: 10.1016/J.Neuroscience.2013.08.008  0.449
2013 Jain T, Wager-Miller J, Mackie K, Straiker A. Diacylglycerol lipaseα (DAGLα) and DAGLβ cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. Molecular Pharmacology. 84: 296-302. PMID 23748223 DOI: 10.1124/mol.113.085217  0.813
2013 Cristino L, Busetto G, Imperatore R, Ferrandino I, Palomba L, Silvestri C, Petrosino S, Orlando P, Bentivoglio M, Mackie K, Di Marzo V. Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: E2229-38. PMID 23630288 DOI: 10.1073/Pnas.1219485110  0.392
2013 Li K, Fichna J, Schicho R, Saur D, Bashashati M, Mackie K, Li Y, Zimmer A, Göke B, Sharkey KA, Storr M. A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. Neuropharmacology. 71: 255-63. PMID 23603203 DOI: 10.1016/J.Neuropharm.2013.03.029  0.631
2013 Straiker A, Min KT, Mackie K. Fmr1 deletion enhances and ultimately desensitizes CB(1) signaling in autaptic hippocampal neurons. Neurobiology of Disease. 56: 1-5. PMID 23578490 DOI: 10.1016/J.Nbd.2013.04.002  0.811
2013 Wu CS, Chen H, Sun H, Zhu J, Jew CP, Wager-Miller J, Straiker A, Spencer C, Bradshaw H, Mackie K, Lu HC. GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination. Plos One. 8: e60314. PMID 23565223 DOI: 10.1371/journal.pone.0060314  0.767
2013 Cottone E, Pomatto V, Cerri F, Campantico E, Mackie K, Delpero M, Guastalla A, Dati C, Bovolin P, Franzoni MF. Cannabinoid receptors are widely expressed in goldfish: Molecular cloning of a CB2-like receptor and evaluation of CB1 and CB2 mRNA expression profiles in different organs Fish Physiology and Biochemistry. 39: 1287-1296. PMID 23504102 DOI: 10.1007/s10695-013-9783-9  0.472
2013 Shonesy BC, Wang X, Rose KL, Ramikie TS, Cavener VS, Rentz T, Baucum AJ, Jalan-Sakrikar N, Mackie K, Winder DG, Patel S, Colbran RJ. CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling. Nature Neuroscience. 16: 456-63. PMID 23502535 DOI: 10.1038/Nn.3353  0.385
2013 Fitzgerald ML, Mackie K, Pickel VM. The impact of adolescent social isolation on dopamine D2 and cannabinoid CB1 receptors in the adult rat prefrontal cortex. Neuroscience. 235: 40-50. PMID 23333674 DOI: 10.1016/J.Neuroscience.2013.01.021  0.364
2013 Keimpema E, Tortoriello G, Alpár A, Capsoni S, Arisi I, Calvigioni D, Hu SS, Cattaneo A, Doherty P, Mackie K, Harkany T. Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 1935-40. PMID 23319656 DOI: 10.1073/Pnas.1212563110  0.617
2013 Horne EA, Coy J, Swinney K, Fung S, Cherry AE, Marrs WR, Naydenov AV, Lin YH, Sun X, Keene CD, Grouzmann E, Muchowski P, Bates GP, Mackie K, Stella N. Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models. The European Journal of Neuroscience. 37: 429-40. PMID 23167744 DOI: 10.1111/Ejn.12045  0.443
2013 Veress G, Meszar Z, Muszil D, Avelino A, Matesz K, Mackie K, Nagy I. Characterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons. Brain Structure & Function. 218: 733-50. PMID 22618437 DOI: 10.1007/s00429-012-0425-2  0.476
2012 Péterfi Z, Urbán GM, Papp OI, Németh B, Monyer H, Szabó G, Erdélyi F, Mackie K, Freund TF, Hájos N, Katona I. Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14448-63. PMID 23055515 DOI: 10.1523/Jneurosci.1676-12.2012  0.418
2012 Hu H, Ho W, Mackie K, Pittman QJ, Sharkey KA. Brain CB₁ receptor expression following lipopolysaccharide-induced inflammation. Neuroscience. 227: 211-22. PMID 23041513 DOI: 10.1016/J.Neuroscience.2012.09.067  0.541
2012 Jung KM, Sepers M, Henstridge CM, Lassalle O, Neuhofer D, Martin H, Ginger M, Frick A, DiPatrizio NV, Mackie K, Katona I, Piomelli D, Manzoni OJ. Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nature Communications. 3: 1080. PMID 23011134 DOI: 10.1038/Ncomms2045  0.548
2012 Murataeva N, Mackie K, Straiker A. The CB2-preferring agonist JWH015 also potently and efficaciously activates CB1 in autaptic hippocampal neurons. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 66: 437-42. PMID 22921769 DOI: 10.1016/J.Phrs.2012.08.002  0.839
2012 Pickel VM, Shobin ET, Lane DA, Mackie K. Cannabinoid-1 receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting N-acylphosphatidylethanolamine-hydrolyzing phospholipase D terminals. Neuroscience. 227: 10-21. PMID 22863674 DOI: 10.1016/j.neuroscience.2012.07.050  0.326
2012 Gregg LC, Jung KM, Spradley JM, Nyilas R, Suplita RL, Zimmer A, Watanabe M, Mackie K, Katona I, Piomelli D, Hohmann AG. Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9457-68. PMID 22787031 DOI: 10.1523/Jneurosci.0013-12.2012  0.576
2012 Ferreira SG, Teixeira FM, Garção P, Agostinho P, Ledent C, Cortes L, MacKie K, Köfalvi A. Presynaptic CB1 cannabinoid receptors control frontocortical serotonin and glutamate release - Species differences Neurochemistry International. 61: 219-226. PMID 22609378 DOI: 10.1016/j.neuint.2012.05.009  0.331
2012 Fitzgerald ML, Chan J, Mackie K, Lupica CR, Pickel VM. Altered dendritic distribution of dopamine D2 receptors and reduction in mitochondrial number in parvalbumin-containing interneurons in the medial prefrontal cortex of cannabinoid-1 (CB1) receptor knockout mice. The Journal of Comparative Neurology. 520: 4013-31. PMID 22592925 DOI: 10.1002/Cne.23141  0.419
2012 Atwood BK, Straiker A, Mackie K. CBâ‚‚ cannabinoid receptors inhibit synaptic transmission when expressed in cultured autaptic neurons. Neuropharmacology. 63: 514-23. PMID 22579668 DOI: 10.1016/J.Neuropharm.2012.04.024  0.817
2012 Hegyi Z, Holló K, Kis G, Mackie K, Antal M. Differential distribution of diacylglycerol lipase-alpha and N-acylphosphatidylethanolamine-specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats. Glia. 60: 1316-29. PMID 22573306 DOI: 10.1002/glia.22351  0.335
2012 Pacher P, Mackie K. Interplay of cannabinoid 2 (CB2) receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration Journal of Molecular Medicine. 90: 347-351. PMID 22371074 DOI: 10.1007/s00109-012-0884-1  0.409
2012 Rajesh M, Bátkai S, Kechrid M, Mukhopadhyay P, Lee WS, Horváth B, Holovac E, Cinar R, Liaudet L, Mackie K, Haskó G, Pacher P. Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy. Diabetes. 61: 716-27. PMID 22315315 DOI: 10.2337/db11-0477  0.412
2012 Hons IM, Storr MA, Mackie K, Lutz B, Pittman QJ, Mawe GM, Sharkey KA. Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 24: e113-24. PMID 22235973 DOI: 10.1111/J.1365-2982.2011.01860.X  0.6
2012 Keimpema E, Straiker A, Mackie K, Harkany T, Hjerling-Leffler J. Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells. The Journal of Physiology. 590: 703-14. PMID 22219340 DOI: 10.1113/Jphysiol.2011.224386  0.755
2012 Atwood BK, Straiker A, Mackie K. CBâ‚‚: therapeutic target-in-waiting. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 38: 16-20. PMID 22197668 DOI: 10.1016/J.Pnpbp.2011.12.001  0.808
2012 Lane DA, Chan J, Fitzgerald ML, Kearn CS, Mackie K, Pickel VM. Quinpirole elicits differential in vivo changes in the pre- and postsynaptic distributions of dopamine D₂ receptors in mouse striatum: relation to cannabinoid-1 (CB₁) receptor targeting. Psychopharmacology. 221: 101-13. PMID 22160162 DOI: 10.1007/S00213-011-2553-4  0.366
2012 Atwood BK, Wager-Miller J, Haskins C, Straiker A, Mackie K. Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands. Molecular Pharmacology. 81: 250-63. PMID 22064678 DOI: 10.1124/Mol.111.074013  0.844
2012 Straiker A, Wager-Miller J, Hutchens J, Mackie K. Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones. British Journal of Pharmacology. 165: 2660-71. PMID 22014238 DOI: 10.1111/j.1476-5381.2011.01744.x  0.835
2012 Straiker A, Wager-Miller J, Mackie K. The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones. British Journal of Pharmacology. 165: 2652-9. PMID 22014214 DOI: 10.1111/j.1476-5381.2011.01743.x  0.834
2012 López-Gallardo M, López-Rodríguez AB, Llorente-Berzal Á, Rotllant D, Mackie K, Armario A, Nadal R, Viveros MP. Maternal deprivation and adolescent cannabinoid exposure impact hippocampal astrocytes, CB1 receptors and brain-derived neurotrophic factor in a sexually dimorphic fashion. Neuroscience. 204: 90-103. PMID 22001306 DOI: 10.1016/J.Neuroscience.2011.09.063  0.329
2012 Bashashati M, Storr MA, Nikas SP, Wood JT, Godlewski G, Liu J, Ho W, Keenan CM, Zhang H, Alapafuja SO, Cravatt BF, Lutz B, Mackie K, Kunos G, Patel KD, et al. Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice. British Journal of Pharmacology. 165: 1556-71. PMID 21883147 DOI: 10.1111/J.1476-5381.2011.01644.X  0.571
2012 Morgan DJ, Muller CH, Murataeva NA, Davis BJ, Mackie K. Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity. British Journal of Pharmacology. 165: 2575-83. PMID 21615727 DOI: 10.1111/J.1476-5381.2011.01506.X  0.777
2011 Ho YC, Lee HJ, Tung LW, Liao YY, Fu SY, Teng SF, Liao HT, Mackie K, Chiou LC. Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14600-10. PMID 21994376 DOI: 10.1523/Jneurosci.2671-11.2011  0.445
2011 Duffy AM, Fitzgerald ML, Chan J, Robinson DC, Milner TA, Mackie K, Pickel VM. Acetylcholine α7 nicotinic and dopamine D2 receptors are targeted to many of the same postsynaptic dendrites and astrocytes in the rodent prefrontal cortex. Synapse (New York, N.Y.). 65: 1350-67. PMID 21858872 DOI: 10.1002/Syn.20977  0.33
2011 Hill MN, McLaughlin RJ, Pan B, Fitzgerald ML, Roberts CJ, Lee TT, Karatsoreos IN, Mackie K, Viau V, Pickel VM, McEwen BS, Liu QS, Gorzalka BB, Hillard CJ. Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10506-15. PMID 21775596 DOI: 10.1523/Jneurosci.0496-11.2011  0.461
2011 Keimpema E, Mackie K, Harkany T. Molecular model of cannabis sensitivity in developing neuronal circuits. Trends in Pharmacological Sciences. 32: 551-61. PMID 21757242 DOI: 10.1016/J.Tips.2011.05.004  0.476
2011 Schicho R, Bashashati M, Bawa M, McHugh D, Saur D, Hu HM, Zimmer A, Lutz B, Mackie K, Bradshaw HB, McCafferty DM, Sharkey KA, Storr M. The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. Inflammatory Bowel Diseases. 17: 1651-64. PMID 21744421 DOI: 10.1002/Ibd.21538  0.556
2011 Straiker A, Wager-Miller J, Hu SS, Blankman JL, Cravatt BF, Mackie K. COX-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation. British Journal of Pharmacology. 164: 1672-83. PMID 21564090 DOI: 10.1111/J.1476-5381.2011.01486.X  0.794
2011 Hemmings HC, Mackie K. The rivers of Lethe and Mnemosyne converge: propofol and memory consolidation. Anesthesiology. 114: 1277-9. PMID 21532461 DOI: 10.1097/ALN.0b013e31821c647d  0.468
2011 Mulder J, Zilberter M, Pasquaré SJ, Alpár A, Schulte G, Ferreira SG, Köfalvi A, Martín-Moreno AM, Keimpema E, Tanila H, Watanabe M, Mackie K, Hortobágyi T, de Ceballos ML, Harkany T. Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. Brain : a Journal of Neurology. 134: 1041-60. PMID 21459826 DOI: 10.1093/Brain/Awr046  0.418
2011 Atwood BK, Lee D, Straiker A, Widlanski TS, Mackie K. CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists. European Journal of Pharmacology. 659: 139-45. PMID 21333643 DOI: 10.1016/J.Ejphar.2011.01.066  0.837
2011 Atwood BK, Lopez J, Wager-Miller J, Mackie K, Straiker A. Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis. Bmc Genomics. 12: 14. PMID 21214938 DOI: 10.1186/1471-2164-12-14  0.8
2011 Carey MR, Myoga MH, McDaniels KR, Marsicano G, Lutz B, Mackie K, Regehr WG. Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses. Journal of Neurophysiology. 105: 958-63. PMID 21084685 DOI: 10.1152/Jn.00980.2010  0.333
2011 Ludányi A, Hu SS, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. Neuroscience. 174: 50-63. PMID 21035522 DOI: 10.1016/J.Neuroscience.2010.10.062  0.524
2011 Halleskog C, Mulder J, Dahlström J, Mackie K, Hortobágyi T, Tanila H, Kumar Puli L, Färber K, Harkany T, Schulte G. WNT signaling in activated microglia is proinflammatory. Glia. 59: 119-31. PMID 20967887 DOI: 10.1002/Glia.21081  0.363
2011 Atwood B, MacKie K. Reply by authors to letter from Ashton British Journal of Pharmacology. 163: 1114. DOI: 10.1111/J.1476-5381.2010.01140.X  0.722
2011 Ludányi A, Hu SSJ, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. Corrigendum to "Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus". [Neuroscience 174 (2011) 50-63]. Neuroscience. 186: 220. DOI: 10.1016/J.Neuroscience.2011.04.072  0.433
2010 Pertwee RG, Howlett AC, Abood ME, Alexander SP, Di Marzo V, Elphick MR, Greasley PJ, Hansen HS, Kunos G, Mackie K, Mechoulam R, Ross RA. International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CBâ‚‚. Pharmacological Reviews. 62: 588-631. PMID 21079038 DOI: 10.1124/Pr.110.003004  0.496
2010 Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC. Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. The European Journal of Neuroscience. 32: 693-706. PMID 21050275 DOI: 10.1111/j.1460-9568.2010.07337.x  0.348
2010 Dmitrieva N, Nagabukuro H, Resuehr D, Zhang G, McAllister SL, McGinty KA, Mackie K, Berkley KJ. Endocannabinoid involvement in endometriosis. Pain. 151: 703-10. PMID 20833475 DOI: 10.1016/J.Pain.2010.08.037  0.331
2010 Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, ... ... Mackie K, et al. The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nature Neuroscience. 13: 951-7. PMID 20657592 DOI: 10.1038/Nn.2601  0.646
2010 Hu SS, Arnold A, Hutchens JM, Radicke J, Cravatt BF, Wager-Miller J, Mackie K, Straiker A. Architecture of cannabinoid signaling in mouse retina. The Journal of Comparative Neurology. 518: 3848-66. PMID 20653038 DOI: 10.1002/Cne.22429  0.819
2010 Maglóczky Z, Tóth K, Karlócai R, Nagy S, Eross L, Czirják S, Vajda J, Rásonyi G, Kelemen A, Juhos V, Halász P, Mackie K, Freund TF. Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans. Epilepsia. 51: 115-20. PMID 20618415 DOI: 10.1111/J.1528-1167.2010.02624.X  0.46
2010 Rajesh M, Mukhopadhyay P, Haskó G, Liaudet L, Mackie K, Pacher P. Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells British Journal of Pharmacology. 160: 688-700. PMID 20590572 DOI: 10.1111/J.1476-5381.2010.00712.X  0.413
2010 Mukhopadhyay P, Pan H, Rajesh M, Bátkai S, Patel V, Harvey-White J, Mukhopadhyay B, Haskó G, Gao B, Mackie K, Pacher P. CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. British Journal of Pharmacology. 160: 657-68. PMID 20590569 DOI: 10.1111/j.1476-5381.2010.00769.x  0.401
2010 Atwood BK, Mackie K. CB2: a cannabinoid receptor with an identity crisis. British Journal of Pharmacology. 160: 467-79. PMID 20590558 DOI: 10.1111/J.1476-5381.2010.00729.X  0.734
2010 Massa F, Mancini G, Schmidt H, Steindel F, Mackie K, Angioni C, Oliet SH, Geisslinger G, Lutz B. Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6273-81. PMID 20445053 DOI: 10.1523/JNEUROSCI.2648-09.2010  0.457
2010 Mukhopadhyay B, Liu J, Osei-Hyiaman D, Godlewski G, Mukhopadhyay P, Wang L, Jeong WI, Gao B, Duester G, Mackie K, Kojima S, Kunos G. Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-γ Journal of Biological Chemistry. 285: 19002-19011. PMID 20410309 DOI: 10.1074/jbc.M109.068460  0.363
2010 Storr MA, Bashashati M, Hirota C, Vemuri VK, Keenan CM, Duncan M, Lutz B, Mackie K, Makriyannis A, Macnaughton WK, Sharkey KA. Differential effects of CB(1) neutral antagonists and inverse agonists on gastrointestinal motility in mice. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22: 787-96, e223. PMID 20180825 DOI: 10.1111/J.1365-2982.2010.01478.X  0.609
2010 Atwood BK, Huffman J, Straiker A, Mackie K. JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist. British Journal of Pharmacology. 160: 585-93. PMID 20100276 DOI: 10.1111/J.1476-5381.2009.00582.X  0.854
2010 Walsh S, Mnich K, Mackie K, Gorman AM, Finn DP, Dowd E. Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat. Brain Research Bulletin. 81: 543-8. PMID 20097273 DOI: 10.1016/j.brainresbull.2010.01.009  0.412
2010 Carvalho AF, Mackie K, Van Bockstaele EJ. Cannabinoid modulation of limbic forebrain noradrenergic circuitry. The European Journal of Neuroscience. 31: 286-301. PMID 20074224 DOI: 10.1111/j.1460-9568.2009.07054.x  0.406
2010 Trimpin S, Herath TN, Inutan ED, Wager-Miller J, Kowalski P, Claude E, Walker JM, Mackie K. Automated solvent-free matrix deposition for tissue imaging by mass spectrometry. Analytical Chemistry. 82: 359-67. PMID 19968249 DOI: 10.1021/Ac902065U  0.313
2010 Mukhopadhyay P, Rajesh M, Bátkai S, Patel V, Kashiwaya Y, Liaudet L, Evgenov OV, Mackie K, Haskó G, Pacher P. CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. Cardiovascular Research. 85: 773-84. PMID 19942623 DOI: 10.1093/cvr/cvp369  0.367
2010 Lipina C, Stretton C, Hastings S, Hundal JS, Mackie K, Irving AJ, Hundal HS. Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells. Diabetes. 59: 375-85. PMID 19933999 DOI: 10.2337/db09-0979  0.386
2010 Scavone JL, Mackie K, Van Bockstaele EJ. Characterization of cannabinoid-1 receptors in the locus coeruleus: relationship with mu-opioid receptors. Brain Research. 1312: 18-31. PMID 19931229 DOI: 10.1016/j.brainres.2009.11.023  0.373
2010 Roche M, Johnston P, Mhuircheartaigh ON, Olango WM, Mackie K, Finn DP. Effects of intra-basolateral amygdala administration of rimonabant on nociceptive behaviour and neuronal activity in the presence or absence of contextual fear. European Journal of Pain (London, England). 14: 487-95. PMID 19786358 DOI: 10.1016/j.ejpain.2009.08.009  0.368
2009 Yao B, Mackie K. Endocannabinoid receptor pharmacology. Current Topics in Behavioral Neurosciences. 1: 37-63. PMID 21104379 DOI: 10.1007/978-3-540-88955-7_2  0.509
2009 Whyte LS, Ryberg E, Sims NA, Ridge SA, Mackie K, Greasley PJ, Ross RA, Rogers MJ. The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 16511-6. PMID 19805329 DOI: 10.1073/pnas.0902743106  0.339
2009 Straiker A, Hu SS, Long JZ, Arnold A, Wager-Miller J, Cravatt BF, Mackie K. Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons. Molecular Pharmacology. 76: 1220-7. PMID 19767452 DOI: 10.1124/Mol.109.059030  0.819
2009 Mackie K, Katona I. Get stoned in GABAergic synapses. Nature Neuroscience. 12: 1081-3. PMID 19710646 DOI: 10.1038/Nn0909-1081  0.325
2009 Straiker A, Mackie K. Cannabinoid signaling in inhibitory autaptic hippocampal neurons. Neuroscience. 163: 190-201. PMID 19501632 DOI: 10.1016/j.neuroscience.2009.06.004  0.8
2009 Kellogg R, Mackie K, Straiker A. Cannabinoid CB1 receptor-dependent long-term depression in autaptic excitatory neurons. Journal of Neurophysiology. 102: 1160-71. PMID 19494194 DOI: 10.1152/jn.00266.2009  0.821
2009 Cottone E, Guastalla A, Pomatto V, Campantico E, Palermo F, Magni AMP, Mackie K, Franzoni MF. Interplay of the Endocannabinoid System with Neuropeptide Y and Corticotropin-releasing Factor in the Goldfish Forebrain Annals of the New York Academy of Sciences. 1163: 372-375. PMID 19456363 DOI: 10.1111/J.1749-6632.2009.04432.X  0.324
2009 Nyilas R, Gregg LC, Mackie K, Watanabe M, Zimmer A, Hohmann AG, Katona I. Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia. The European Journal of Neuroscience. 29: 1964-78. PMID 19453631 DOI: 10.1111/J.1460-9568.2009.06751.X  0.385
2009 Trabucco E, Acone G, Marenna A, Pierantoni R, Cacciola G, Chioccarelli T, Mackie K, Fasano S, Colacurci N, Meccariello R, Cobellis G, Cobellis L. Endocannabinoid system in first trimester placenta: low FAAH and high CB1 expression characterize spontaneous miscarriage. Placenta. 30: 516-522. PMID 19419760 DOI: 10.1016/J.Placenta.2009.03.015  0.341
2009 Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/Nchembio0309-131  0.549
2009 Acone G, Trabucco E, Colacurci N, Cobellis L, Mackie K, Meccariello R, Cacciola G, Chioccarelli T, Fasano S, Pierantoni R, Cobellis G. Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. Placenta. 30: 203-205. PMID 19097644 DOI: 10.1016/J.Placenta.2008.11.018  0.397
2009 Whyte L, Ryberg E, Sims NA, Ridge S, Mackie K, Greasley P, Ross RA, Rogers MJ. GPR55: A novel cannabinoid receptor involved in the regulation of osteoclast function and bone mass Bone. 44. DOI: 10.1016/J.Bone.2009.01.305  0.367
2008 Harkany T, Mackie K, Doherty P. Wiring and firing neuronal networks: endocannabinoids take center stage. Current Opinion in Neurobiology. 18: 338-45. PMID 18801434 DOI: 10.1016/J.Conb.2008.08.007  0.406
2008 Cacciola G, Chioccarelli T, Mackie K, Meccariello R, Ledent C, Fasano S, Pierantoni R, Cobellis G. Expression of Type-1 Cannabinoid Receptor During Rat Postnatal Testicular Development: Possible Involvement in Adult Leydig Cell Differentiation Biology of Reproduction. 79: 758-765. PMID 18614700 DOI: 10.1095/Biolreprod.108.070128  0.41
2008 Mulder J, Aguado T, Keimpema E, Barabás K, Ballester Rosado CJ, Nguyen L, Monory K, Marsicano G, Di Marzo V, Hurd YL, Guillemot F, Mackie K, Lutz B, Guzmán M, Lu HC, et al. Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proceedings of the National Academy of Sciences of the United States of America. 105: 8760-5. PMID 18562289 DOI: 10.1073/Pnas.0803545105  0.316
2008 Suárez J, Bermúdez-Silva FJ, Mackie K, Ledent C, Zimmer A, Cravatt BF, de Fonseca FR. Immunohistochemical description of the endogenous cannabinoid system in the rat cerebellum and functionally related nuclei. The Journal of Comparative Neurology. 509: 400-21. PMID 18521853 DOI: 10.1002/Cne.21774  0.396
2008 Moussaieff A, Rimmerman N, Bregman T, Straiker A, Felder CC, Shoham S, Kashman Y, Huang SM, Lee H, Shohami E, Mackie K, Caterina MJ, Walker JM, Fride E, Mechoulam R. Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3024-34. PMID 18492727 DOI: 10.1096/Fj.07-101865  0.785
2008 Duncan M, Mouihate A, Mackie K, Keenan CM, Buckley NE, Davison JS, Patel KD, Pittman QJ, Sharkey KA. Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G78-G87. PMID 18483180 DOI: 10.1152/Ajpgi.90285.2008  0.629
2008 Mackie K. Cannabinoid Receptors: Where They are and What They do Journal of Neuroendocrinology. 20: 10-14. PMID 18426493 DOI: 10.1111/J.1365-2826.2008.01671.X  0.459
2008 Cinar R, Freund TF, Katona I, Mackie K, Szucs M. Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes. Neurochemistry International. 52: 1402-9. PMID 18407377 DOI: 10.1016/J.Neuint.2008.02.005  0.454
2008 Cottone E, Guastalla A, Mackie K, Franzoni MF. Endocannabinoids affect the reproductive functions in teleosts and amphibians. Molecular and Cellular Endocrinology. 286. PMID 18343023 DOI: 10.1016/J.Mce.2008.01.025  0.502
2008 Mackie K. Signaling via CNS cannabinoid receptors. Molecular and Cellular Endocrinology. 286. PMID 18336996 DOI: 10.1016/J.Mce.2008.01.022  0.529
2008 Daigle TL, Kwok ML, Mackie K. Regulation of CB1 cannabinoid receptor internalization by a promiscuous phosphorylation-dependent mechanism. Journal of Neurochemistry. 106: 70-82. PMID 18331587 DOI: 10.1111/j.1471-4159.2008.05336.x  0.738
2008 Lauckner JE, Jensen JB, Chen HY, Lu HC, Hille B, Mackie K. GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proceedings of the National Academy of Sciences of the United States of America. 105: 2699-704. PMID 18263732 DOI: 10.1073/Pnas.0711278105  0.836
2008 Nyilas R, Dudok B, Urbán GM, Mackie K, Watanabe M, Cravatt BF, Freund TF, Katona I. Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1058-63. PMID 18234884 DOI: 10.1523/Jneurosci.5102-07.2008  0.4
2008 Malone DT, Kearn CS, Chongue L, Mackie K, Taylor DA. Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in rats. Neuroscience. 152: 265-72. PMID 18082330 DOI: 10.1016/j.neuroscience.2007.10.043  0.375
2008 Rajesh M, Mukhopadhyay P, Haskó G, Huffman JW, Mackie K, Pacher P. CB2 cannabinoid receptor agonists attenuate TNF-α-induced human vascular smooth muscle cell proliferation and migration British Journal of Pharmacology. 153: 347-357. PMID 17994109 DOI: 10.1038/Sj.Bjp.0707569  0.414
2008 Rimmerman N, Hughes HV, Bradshaw HB, Pazos MX, Mackie K, Prieto AL, Walker JM. Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line. British Journal of Pharmacology. 153: 380-9. PMID 17965731 DOI: 10.1038/Sj.Bjp.0707561  0.447
2008 Daigle TL, Kearn CS, Mackie K. Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling. Neuropharmacology. 54: 36-44. PMID 17681354 DOI: 10.1016/j.neuropharm.2007.06.005  0.786
2008 Mátyás F, Urbán GM, Watanabe M, Mackie K, Zimmer A, Freund TF, Katona I. Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area. Neuropharmacology. 54: 95-107. PMID 17655884 DOI: 10.1016/J.Neuropharm.2007.05.028  0.372
2008 Nesto RW, Mackie K. Endocannabinoid system and its implications for obesity and cardiometabolic risk European Heart Journal. 10. DOI: 10.1093/Eurheartj/Sum052  0.303
2008 Mackie K, Ross RA. CB 2 cannabinoid receptors: New vistas British Journal of Pharmacology. 153: 177-178. DOI: 10.1038/sj.bjp.0707617  0.477
2007 Cachope R, Mackie K, Triller A, O'Brien J, Pereda AE. Potentiation of electrical and chemical synaptic transmission mediated by endocannabinoids. Neuron. 56: 1034-47. PMID 18093525 DOI: 10.1016/J.Neuron.2007.11.014  0.359
2007 Mackie K. From active ingredients to the discovery of the targets: the cannabinoid receptors. Chemistry & Biodiversity. 4: 1693-1706. PMID 17712815 DOI: 10.1002/Cbdv.200790148  0.433
2007 Rajesh M, Mukhopadhyay P, Batkai S, Hasko G, Liaudet L, Huffman JW, Csiszar A, Ungvari ZI, Mackie K, Chatterjee S, Pacher P. CB2-receptor stimulation attenuates TNF-α-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion American Journal of Physiology-Heart and Circulatory Physiology. 293. PMID 17660390 DOI: 10.1152/Ajpheart.00688.2007  0.409
2007 Jung KM, Astarita G, Zhu C, Wallace M, Mackie K, Piomelli D. A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization. Molecular Pharmacology. 72: 612-21. PMID 17584991 DOI: 10.1124/Mol.107.037796  0.532
2007 Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin CE, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, et al. Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nature Neuroscience. 10: 870-9. PMID 17558404 DOI: 10.1038/Nn1916  0.446
2007 Berghuis P, Rajnicek AM, Morozov YM, Ross RA, Mulder J, Urbán GM, Monory K, Marsicano G, Matteoli M, Canty A, Irving AJ, Katona I, Yanagawa Y, Rakic P, Lutz B, ... Mackie K, et al. Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science (New York, N.Y.). 316: 1212-6. PMID 17525344 DOI: 10.1126/Science.1137406  0.381
2007 Castelli MP, Piras AP, Melis T, Succu S, Sanna F, Melis MR, Collu S, Ennas MG, Diaz G, Mackie K, Argiolas A. Cannabinoid CB1 receptors in the paraventricular nucleus and central control of penile erection: immunocytochemistry, autoradiography and behavioral studies. Neuroscience. 147: 197-206. PMID 17507169 DOI: 10.1016/j.neuroscience.2007.02.062  0.476
2007 Tappe-Theodor A, Agarwal N, Katona I, Rubino T, Martini L, Swiercz J, Mackie K, Monyer H, Parolaro D, Whistler J, Kuner T, Kuner R. A molecular basis of analgesic tolerance to cannabinoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4165-77. PMID 17428994 DOI: 10.1523/Jneurosci.5648-06.2007  0.477
2007 Mitrirattanakul S, López-Valdés HE, Liang J, Matsuka Y, Mackie K, Faull KF, Spigelman I. Bidirectional alterations of hippocampal cannabinoid 1 receptors and their endogenous ligands in a rat model of alcohol withdrawal and dependence. Alcoholism, Clinical and Experimental Research. 31: 855-67. PMID 17386072 DOI: 10.1111/J.1530-0277.2007.00366.X  0.342
2007 Harkany T, Guzmán M, Galve-Roperh I, Berghuis P, Devi LA, Mackie K. The emerging functions of endocannabinoid signaling during CNS development. Trends in Pharmacological Sciences. 28: 83-92. PMID 17222464 DOI: 10.1016/J.Tips.2006.12.004  0.347
2007 Duarte JM, Nogueira C, Mackie K, Oliveira CR, Cunha RA, Köfalvi A. Increase of cannabinoid CB1 receptor density in the hippocampus of streptozotocin-induced diabetic rats. Experimental Neurology. 204: 479-84. PMID 17222407 DOI: 10.1016/j.expneurol.2006.11.013  0.35
2007 Deshmukh S, Onozuka K, Bender KJ, Bender VA, Lutz B, Mackie K, Feldman DE. Postnatal development of cannabinoid receptor type 1 expression in rodent somatosensory cortex. Neuroscience. 145: 279-87. PMID 17210229 DOI: 10.1016/J.Neuroscience.2006.11.033  0.44
2007 Chen K, Neu A, Howard AL, Földy C, Echegoyen J, Hilgenberg L, Smith M, Mackie K, Soltesz I. Prevention of plasticity of endocannabinoid signaling inhibits persistent limbic hyperexcitability caused by developmental seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 46-58. PMID 17202471 DOI: 10.1523/Jneurosci.3966-06.2007  0.366
2007 Fu J, Astarita G, Gaetani S, Kim J, Cravatt BF, Mackie K, Piomelli D. Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine. The Journal of Biological Chemistry. 282: 1518-28. PMID 17121838 DOI: 10.1074/Jbc.M607809200  0.511
2007 Oropeza VC, Mackie K, Van Bockstaele EJ. Cannabinoid receptors are localized to noradrenergic axon terminals in the rat frontal cortex. Brain Research. 1127: 36-44. PMID 17113043 DOI: 10.1016/j.brainres.2006.09.110  0.384
2007 Straiker A, Mackie K. Metabotropic suppression of excitation in murine autaptic hippocampal neurons. The Journal of Physiology. 578: 773-85. PMID 17110416 DOI: 10.1113/jphysiol.2006.117499  0.837
2006 Cenni G, Blandina P, Mackie K, Nosi D, Formigli L, Giannoni P, Ballini C, Corte LD, Mannaioni PF, Passani MB. Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain. European Journal of Neuroscience. 24: 1633-1644. PMID 17004927 DOI: 10.1111/J.1460-9568.2006.05046.X  0.352
2006 Monory K, Massa F, Egertová M, Eder M, Blaudzun H, Westenbroek R, Kelsch W, Jacob W, Marsch R, Ekker M, Long J, Rubenstein JL, Goebbels S, Nave KA, During M, ... ... Mackie K, et al. The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron. 51: 455-66. PMID 16908411 DOI: 10.1016/J.Neuron.2006.07.006  0.399
2006 Mitrirattanakul S, Ramakul N, Guerrero AV, Matsuka Y, Ono T, Iwase H, Mackie K, Faull KF, Spigelman I. Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain. Pain. 126: 102-14. PMID 16844297 DOI: 10.1016/J.Pain.2006.06.016  0.357
2006 Mackie K, Stella N. Cannabinoid receptors and endocannabinoids: evidence for new players. The Aaps Journal. 8: E298-306. PMID 16796380 DOI: 10.1208/aapsj080234  0.53
2006 Straiker A, Mackie K. Cannabinoids, electrophysiology, and retrograde messengers: challenges for the next 5 years. The Aaps Journal. 8: E272-6. PMID 16796377 DOI: 10.1208/aapsj080231  0.818
2006 Katona I, Urbán GM, Wallace M, Ledent C, Jung KM, Piomelli D, Mackie K, Freund TF. Molecular composition of the endocannabinoid system at glutamatergic synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5628-37. PMID 16723519 DOI: 10.1523/Jneurosci.0309-06.2006  0.533
2006 Cobellis G, Cacciola G, Scarpa D, Meccariello R, Chianese R, Franzoni MF, Mackie K, Pierantoni R, Fasano S. Endocannabinoid System in Frog and Rodent Testis: Type-1 Cannabinoid Receptor and Fatty Acid Amide Hydrolase Activity in Male Germ Cells Biology of Reproduction. 75: 82-89. PMID 16611862 DOI: 10.1095/Biolreprod.106.051730  0.414
2006 Mackie K. Mechanisms of CB1 receptor signaling: endocannabinoid modulation of synaptic strength. International Journal of Obesity. 30. PMID 16570100 DOI: 10.1038/Sj.Ijo.0803273  0.521
2006 Pickel VM, Chan J, Kearn CS, Mackie K. Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbens. The Journal of Comparative Neurology. 495: 299-313. PMID 16440297 DOI: 10.1002/cne.20881  0.446
2006 Mackie K. Cannabinoid receptors as therapeutic targets. Annual Review of Pharmacology and Toxicology. 46: 101-122. PMID 16402900 DOI: 10.1146/Annurev.Pharmtox.46.120604.141254  0.466
2006 Mátyás F, Yanovsky Y, Mackie K, Kelsch W, Misgeld U, Freund TF. Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia. Neuroscience. 137: 337-61. PMID 16289348 DOI: 10.1016/J.Neuroscience.2005.09.005  0.467
2005 Mackie K. Distribution of cannabinoid receptors in the central and peripheral nervous system. Handbook of Experimental Pharmacology. 168: 299-325. PMID 16596779 DOI: 10.1007/3-540-26573-2_10  0.505
2005 Lauckner JE, Hille B, Mackie K. The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins. Proceedings of the National Academy of Sciences of the United States of America. 102: 19144-9. PMID 16365309 DOI: 10.1073/pnas.0509588102  0.807
2005 Berghuis P, Dobszay MB, Wang X, Spano S, Ledda F, Sousa KM, Schulte G, Ernfors P, Mackie K, Paratcha G, Hurd YL, Harkany T. Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 19115-20. PMID 16357196 DOI: 10.1073/Pnas.0509494102  0.478
2005 Nyíri G, Cserép C, Szabadits E, Mackie K, Freund TF. CB1 cannabinoid receptors are enriched in the perisynaptic annulus and on preterminal segments of hippocampal GABAergic axons. Neuroscience. 136: 811-22. PMID 16344153 DOI: 10.1016/j.neuroscience.2005.01.026  0.475
2005 Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, Stella N, Makriyannis A, Piomelli D, Davison JS, Marnett LJ, Di Marzo V, Pittman QJ, Patel KD, Sharkey KA. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science (New York, N.Y.). 310: 329-32. PMID 16224028 DOI: 10.1126/Science.1115740  0.73
2005 Straiker A, Mackie K. Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones. The Journal of Physiology. 569: 501-17. PMID 16179366 DOI: 10.1113/jphysiol.2005.091918  0.813
2005 Osei-Hyiaman D, Depetrillo M, Harvey-White J, Bannon AW, Cravatt BF, Kuhar MJ, Mackie K, Palkovits M, Kunos G. Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. Neuroendocrinology. 81: 273-82. PMID 16131814 DOI: 10.1159/000087925  0.34
2005 Horowitz LF, Hirdes W, Suh BC, Hilgemann DW, Mackie K, Hille B. Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. The Journal of General Physiology. 126: 243-62. PMID 16129772 DOI: 10.1085/Jgp.200509309  0.723
2005 Harkany T, Dobszay MB, Cayetanot F, Härtig W, Siegemund T, Aujard F, Mackie K. Redistribution of CB1 cannabinoid receptors during evolution of cholinergic basal forebrain territories and their cortical projection areas: a comparison between the gray mouse lemur (Microcebus murinus, primates) and rat. Neuroscience. 135: 595-609. PMID 16129564 DOI: 10.1016/J.Neuroscience.2005.06.043  0.479
2005 Jung KM, Mangieri R, Stapleton C, Kim J, Fegley D, Wallace M, Mackie K, Piomelli D. Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. Molecular Pharmacology. 68: 1196-202. PMID 16051747 DOI: 10.1124/Mol.105.013961  0.629
2005 Bodor AL, Katona I, Nyíri G, Mackie K, Ledent C, Hájos N, Freund TF. Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6845-56. PMID 16033894 DOI: 10.1523/Jneurosci.0442-05.2005  0.335
2005 Mackie K. Cannabinoid receptor homo- and heterodimerization. Life Sciences. 77: 1667-1673. PMID 15978631 DOI: 10.1016/J.Lfs.2005.05.011  0.461
2005 Nyíri G, Szabadits E, Cserép C, Mackie K, Shigemoto R, Freund TF. GABAB and CB1 cannabinoid receptor expression identifies two types of septal cholinergic neurons. The European Journal of Neuroscience. 21: 3034-42. PMID 15978014 DOI: 10.1111/j.1460-9568.2005.04146.x  0.323
2005 Osei-Hyiaman D, DePetrillo M, Pacher P, Liu J, Radaeva S, Bátkai S, Harvey-White J, Mackie K, Offertáler L, Wang L, Kunos G. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. The Journal of Clinical Investigation. 115: 1298-305. PMID 15864349 DOI: 10.1172/JCI23057  0.348
2005 Cottone E, Forno S, Campantico E, Guastalla A, Viltono L, Mackie K, Franzoni MF. Expression and distribution of CB1 cannabinoid receptors in the central nervous system of the African cichlid fish Pelvicachromis pulcher. The Journal of Comparative Neurology. 485: 293-303. PMID 15803507 DOI: 10.1002/Cne.20502  0.427
2005 Köfalvi A, Rodrigues RJ, Ledent C, Mackie K, Vizi ES, Cunha RA, Sperlágh B. Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: a combined immunochemical and pharmacological analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2874-84. PMID 15772347 DOI: 10.1523/Jneurosci.4232-04.2005  0.415
2005 Benito C, Kim WK, Kim WK, Chavarría I, Hillard CJ, Mackie K, Tolón RM, Williams K, Williams K, Romero J. A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2530-6. PMID 15758162 DOI: 10.1523/JNEUROSCI.3923-04.2005  0.367
2005 Kearn CS, Blake-Palmer K, Daniel E, Mackie K, Glass M. Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk? Molecular Pharmacology. 67: 1697-704. PMID 15710746 DOI: 10.1124/mol.104.006882  0.491
2004 Bátkai S, Pacher P, Osei-Hyiaman D, Radaeva S, Liu J, Harvey-White J, Offertáler L, Mackie K, Rudd MA, Bukoski RD, Kunos G. Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation. 110: 1996-2002. PMID 15451779 DOI: 10.1161/01.Cir.0000143230.23252.D2  0.333
2004 Hirasawa M, Schwab Y, Natah S, Hillard CJ, Mackie K, Sharkey KA, Pittman QJ. Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain. The Journal of Physiology. 559: 611-24. PMID 15254151 DOI: 10.1113/Jphysiol.2004.066159  0.631
2004 Pickel VM, Chan J, Kash TL, Rodríguez JJ, MacKie K. Compartment-specific localization of cannabinoid 1 (CB1) and mu-opioid receptors in rat nucleus accumbens. Neuroscience. 127: 101-12. PMID 15219673 DOI: 10.1016/j.neuroscience.2004.05.015  0.45
2004 Suh BC, Horowitz LF, Hirdes W, Mackie K, Hille B. Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq. The Journal of General Physiology. 123: 663-83. PMID 15173220 DOI: 10.1085/jgp.200409029  0.727
2004 Harkany T, Holmgren C, Härtig W, Qureshi T, Chaudhry FA, Storm-Mathisen J, Dobszay MB, Berghuis P, Schulte G, Sousa KM, Fremeau RT, Edwards RH, Mackie K, Ernfors P, Zilberter Y. Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4978-88. PMID 15163690 DOI: 10.1523/Jneurosci.4884-03.2004  0.361
2004 Luk T, Jin W, Zvonok A, Lu D, Lin XZ, Chavkin C, Makriyannis A, Mackie K. Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist. British Journal of Pharmacology. 142: 495-500. PMID 15148260 DOI: 10.1038/Sj.Bjp.0705792  0.464
2004 MacNaughton WK, Van Sickle MD, Keenan CM, Cushing K, Mackie K, Sharkey KA. Distribution and function of the cannabinoid-1 receptor in the modulation of ion transport in the guinea pig ileum: relationship to capsaicin-sensitive nerves. American Journal of Physiology. Gastrointestinal and Liver Physiology. 286: G863-71. PMID 14701723 DOI: 10.1152/Ajpgi.00482.2003  0.643
2003 Harkany T, Härtig W, Berghuis P, Dobszay MB, Zilberter Y, Edwards RH, Mackie K, Ernfors P. Complementary distribution of type 1 cannabinoid receptors and vesicular glutamate transporter 3 in basal forebrain suggests input-specific retrograde signalling by cholinergic neurons. The European Journal of Neuroscience. 18: 1979-92. PMID 14622230 DOI: 10.1046/J.1460-9568.2003.02898.X  0.471
2003 Chen K, Ratzliff A, Hilgenberg L, Gulyás A, Freund TF, Smith M, Dinh TP, Piomelli D, Mackie K, Soltesz I. Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures. Neuron. 39: 599-611. PMID 12925275 DOI: 10.1016/S0896-6273(03)00499-9  0.513
2003 McLaughlin JP, Xu M, Mackie K, Chavkin C. Phosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalization. The Journal of Biological Chemistry. 278: 34631-40. PMID 12815037 DOI: 10.1074/Jbc.M304022200  0.474
2003 Van Sickle MD, Oland LD, Mackie K, Davison JS, Sharkey KA. Delta9-tetrahydrocannabinol selectively acts on CB1 receptors in specific regions of dorsal vagal complex to inhibit emesis in ferrets. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G566-76. PMID 12791597 DOI: 10.1152/Ajpgi.00113.2003  0.608
2003 Walter L, Franklin A, Witting A, Wade C, Xie Y, Kunos G, Mackie K, Stella N. Nonpsychotropic cannabinoid receptors regulate microglial cell migration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1398-405. PMID 12598628  0.351
2003 Walter L, Franklin A, Witting A, Wade C, Xie Y, Kunos G, Mackie K, Stella N. Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration The Journal of Neuroscience. 23: 1398-1405. DOI: 10.1523/Jneurosci.23-04-01398.2003  0.458
2003 Macnaughton WK, Cushing K, Van Sickle MD, Keenan CM, Mackie K, Sharkey KA. Cannabinoid CB1 receptor distribution and function in neurally mediated chloride secretion in the guinea pig ileum Gastroenterology. 124: A342. DOI: 10.1016/S0016-5085(03)81726-2  0.594
2002 Wager-Miller J, Westenbroek R, Mackie K. Dimerization of G protein-coupled receptors: CB1 cannabinoid receptors as an example. Chemistry and Physics of Lipids. 121: 83-89. PMID 12505693 DOI: 10.1016/S0009-3084(02)00151-2  0.403
2002 Roche JP, Westenbroek R, Sorom AJ, Hille B, Mackie K, Shapiro MS. Antibodies and a cysteine-modifying reagent show correspondence of M current in neurons to KCNQ2 and KCNQ3 K+ channels. British Journal of Pharmacology. 137: 1173-86. PMID 12466226 DOI: 10.1038/sj.bjp.0704989  0.665
2002 Coutts AA, Irving AJ, Mackie K, Pertwee RG, Anavi-Goffer S. Localisation of cannabinoid CB(1) receptor immunoreactivity in the guinea pig and rat myenteric plexus. The Journal of Comparative Neurology. 448: 410-22. PMID 12115703 DOI: 10.1002/Cne.10270  0.53
2002 Brown SM, Wager-Miller J, Mackie K. Cloning and molecular characterization of the rat CB2 cannabinoid receptor. Biochimica Et Biophysica Acta. 1576: 255-264. PMID 12084572 DOI: 10.1016/S0167-4781(02)00341-X  0.434
2002 Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacological Reviews. 54: 161-202. PMID 12037135 DOI: 10.1124/Pr.54.2.161  0.536
2002 Cesa R, Guastalla A, Cottone E, Mackie K, Beltramo M, Franzoni MF. Relationships between CB1 cannabinoid receptors and pituitary endocrine cells in Xenopus laevis: an immunohistochemical study. General and Comparative Endocrinology. 125: 17-24. PMID 11825030 DOI: 10.1006/Gcen.2001.7720  0.428
2002 Salio C, Fischer J, Franzoni MF, Mackie K, Kaneko T, Conrath M. CB1-cannabinoid and mu-opioid receptor co-localization on postsynaptic target in the rat dorsal horn. Neuroreport. 12: 3689-92. PMID 11726775 DOI: 10.1097/00001756-200112040-00017  0.384
2002 Hsieh C, Brown S, Derleth C, Mackie K. Internalization and Recycling of the CB1 Cannabinoid Receptor Journal of Neurochemistry. 73: 493-501. PMID 10428044 DOI: 10.1046/J.1471-4159.1999.0730493.X  0.489
2002 Diana MA, Levenes C, Mackie K, Marty A. Short-Term Retrograde Inhibition of GABAergic Synaptic Currents in Rat Purkinje Cells Is Mediated by Endogenous Cannabinoids The Journal of Neuroscience. 22: 200-208. DOI: 10.1523/Jneurosci.22-01-00200.2002  0.389
2001 Cesa R, Mackie K, Beltramo M, Franzoni MF. Cannabinoid receptor CB1-like and glutamic acid decarboxylase-like immunoreactivities in the brain of Xenopus laevis Cell and Tissue Research. 306: 391-398. PMID 11735039 DOI: 10.1007/S004410100461  0.38
2001 Katona I, Rancz EA, Acsady L, Ledent C, Mackie K, Hajos N, Freund TF. Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9506-18. PMID 11717385 DOI: 10.1523/Jneurosci.21-23-09506.2001  0.511
2001 Van Sickle MD, Oland LD, Ho W, Hillard CJ, Mackie K, Davison JS, Sharkey KA. Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret. Gastroenterology. 121: 767-74. PMID 11606489 DOI: 10.1053/Gast.2001.28466  0.607
2001 Rodriguez JJ, Mackie K, Pickel VM. Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 823-33. PMID 11157068 DOI: 10.1523/Jneurosci.21-03-00823.2001  0.392
2001 Coutts AA, Anavi-Goffer S, Ross RA, MacEwan DJ, Mackie K, Pertwee RG, Irving AJ. Agonist-induced internalization and trafficking of cannabinoid CB1 receptors in hippocampal neurons. The Journal of Neuroscience. 21: 2425-2433. DOI: 10.1523/Jneurosci.21-07-02425.2001  0.521
2001 Rodrı́guez JJ, Mackie K, Pickel VM. Ultrastructural Localization of the CB1 Cannabinoid Receptor in μ-Opioid Receptor Patches of the Rat Caudate Putamen Nucleus The Journal of Neuroscience. 21: 823-833. DOI: 10.1523/JNEUROSCI.21-03-00823.2001  0.311
2001 Van Sickle MD, Oland LD, Mackie K, Davison JS, Sharkey KA. Distribution of the cannabinoid 1 receptor in the brainstem and gut: A novel neuroregulatory system in emesis Gastroenterology. 120: A197. DOI: 10.1016/S0016-5085(08)80976-6  0.314
2000 Calignano A, Kátona I, Désarnaud F, Giuffrida A, La Rana G, Mackie K, Freund TF, Piomelli D. Bidirectional control of airway responsiveness by endogenous cannabinoids. Nature. 408: 96-101. PMID 11081515 DOI: 10.1038/35040576  0.525
2000 Katona I, Sperlágh B, Maglóczky Z, Sántha E, Köfalvi A, Czirják S, Mackie K, Vizi ES, Freund TF. GABAergic interneurons are the targets of cannabinoid actions in the human hippocampus. Neuroscience. 100: 797-804. PMID 11036213 DOI: 10.1016/S0306-4522(00)00286-4  0.475
2000 Hájos N, Katona I, Naiem SS, MacKie K, Ledent C, Mody I, Freund TF. Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations. The European Journal of Neuroscience. 12: 3239-49. PMID 10998107 DOI: 10.1046/J.1460-9568.2000.00217.X  0.487
2000 Irving AJ, Coutts AA, Harvey J, Rae MG, Mackie K, Bewick GS, Pertwee RG. Functional expression of cell surface cannabinoid CB(1) receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons. Neuroscience. 98: 253-62. PMID 10854756 DOI: 10.1016/S0306-4522(00)00120-2  0.501
2000 Hernández M, Berrendero F, Suárez I, García-Gil L, Cebeira M, Mackie K, Ramos JA, Fernández-Ruiz J. Cannabinoid CB(1) receptors colocalize with tyrosine hydroxylase in cultured fetal mesencephalic neurons and their activation increases the levels of this enzyme. Brain Research. 857: 56-65. PMID 10700552 DOI: 10.1016/S0006-8993(99)02322-7  0.494
2000 Shapiro MS, Roche JP, Kaftan EJ, Cruzblanca H, Mackie K, Hille B. Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 1710-21. PMID 10684873 DOI: 10.1523/Jneurosci.20-05-01710.2000  0.688
2000 Sañudo-Peña MC, Tsou K, Romero J, Mackie K, Walker JM. Role of the superior colliculus in the motor effects of cannabinoids and dopamine. Brain Research. 853: 207-14. PMID 10640618 DOI: 10.1016/S0006-8993(99)02291-X  0.464
1999 Lu XR, Ong WY, Mackie K. A light and electron microscopic study of the CB1 cannabinoid receptor in monkey basal forebrain Journal of Neurocytology. 28: 1045-1051. PMID 11054904 DOI: 10.1023/A:1007052507911  0.422
1999 Straiker A, Stella N, Piomelli D, Mackie K, Karten HJ, Maguire G. Cannabinoid CB1 receptors and ligands in vertebrate retina: localization and function of an endogenous signaling system. Proceedings of the National Academy of Sciences of the United States of America. 96: 14565-70. PMID 10588745 DOI: 10.1073/Pnas.96.25.14565  0.814
1999 Ong WY, Mackie K. A light and electron microscopic study of the CB1 cannabinoid receptor in the primate spinal cord. Journal of Neurocytology. 28: 39-45. PMID 10573606 DOI: 10.1023/A:1007011700677  0.42
1999 Tsou K, Mackie K, Sañudo-Peña MC, Walker JM. Cannabinoid CB1 receptors are localized primarily on cholecystokinin-containing GABAergic interneurons in the rat hippocampal formation. Neuroscience. 93: 969-75. PMID 10473261 DOI: 10.1016/S0306-4522(99)00086-X  0.531
1999 Roche JP, Bounds S, Brown S, Mackie K. A mutation in the second transmembrane region of the CB1 receptor selectively disrupts G protein signaling and prevents receptor internalization Molecular Pharmacology. 56: 611-618. PMID 10462549 DOI: 10.1124/Mol.56.3.611  0.478
1999 Ong WY, Mackie K. A light and electron microscopic study of the CB1 cannabinoid receptor in primate brain. Neuroscience. 92: 1177-1191. PMID 10426477 DOI: 10.1016/S0306-4522(99)00025-1  0.487
1999 Mackie K, Walker JM. Kang tsou (1932-1999) Trends in Neurosciences. 22: 331. PMID 10407414 DOI: 10.1016/S0166-2236(99)01450-2  0.436
1999 Katona I, Sperlágh B, Sík A, Käfalvi A, Vizi ES, Mackie K, Freund TF. Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4544-58. PMID 10341254 DOI: 10.1523/Jneurosci.19-11-04544.1999  0.427
1999 Jin W, Brown S, Roche JP, Hsieh C, Celver JP, Kovoor A, Chavkin C, Mackie K. Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3773-80. PMID 10234009 DOI: 10.1523/Jneurosci.19-10-03773.1999  0.471
1998 García DE, Li B, García-Ferreiro RE, Hernández-Ochoa EO, Yan K, Gautam N, Catterall WA, Mackie K, Hille B. G-protein beta-subunit specificity in the fast membrane-delimited inhibition of Ca2+ channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9163-70. PMID 9801356  0.714
1998 Garcia DE, Brown S, Hille B, Mackie K. Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2834-41. PMID 9526000 DOI: 10.1523/Jneurosci.18-08-02834.1998  0.766
1998 Tsou K, Brown S, Sañudo-Peña MC, Mackie K, Walker JM. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience. 83: 393-411. PMID 9460749 DOI: 10.1016/S0306-4522(97)00436-3  0.492
1998 Felder CC, Joyce KE, Briley EM, Glass M, Mackie KP, Fahey KJ, Cullinan GJ, Hunden DC, Johnson DW, Chaney MO, Koppel GA, Brownstein M. LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation. The Journal of Pharmacology and Experimental Therapeutics. 284: 291-7. PMID 9435190  0.421
1998 Garcı́a DE, Li B, Garcı́a-Ferreiro RE, Hernández-Ochoa EO, Yan K, Gautam N, Catterall WA, Mackie K, Hille B. G-Protein β-Subunit Specificity in the Fast Membrane-Delimited Inhibition of Ca2+ Channels The Journal of Neuroscience. 18: 9163-9170. DOI: 10.1523/Jneurosci.18-22-09163.1998  0.673
1997 Twitchell W, Brown S, Mackie K. Cannabinoids Inhibit N- and P/Q-Type Calcium Channels in Cultured Rat Hippocampal Neurons Journal of Neurophysiology. 78: 43-50. PMID 9242259 DOI: 10.1152/Jn.1997.78.1.43  0.308
1996 Herlitze S, Garcia DE, Mackie K, Hille B, Scheuer T, Catterall WA. Modulation of Ca2+ channels by G-protein beta gamma subunits. Nature. 380: 258-62. PMID 8637576 DOI: 10.1038/380258a0  0.728
1996 Herlitze S, Garcia DE, Mackie K, Hille B, Scheuer T, Catterall WA. Erratum: Modulation of Ca2+ channels by G-protein βγ subunits Nature. 381: 172-172. DOI: 10.1038/381172D0  0.678
1995 Mackie K, Lai Y, Westenbroek R, Mitchell R. Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor The Journal of Neuroscience. 15: 6552-6561. DOI: 10.1523/Jneurosci.15-10-06552.1995  0.414
1993 Felder CC, Briley EM, Axelrod J, Simpson JT, Mackie K, Devane WA. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 90: 7656-60. PMID 8395053 DOI: 10.1073/Pnas.90.16.7656  0.487
1992 Mackie K, Hille B. Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 3825-9. PMID 1315042 DOI: 10.1073/Pnas.89.9.3825  0.713
1991 Mackie K, Hille B. CANNABINOIDS INHIBIT A HIGH-THRESHHOLD CALCIUM CURRENT Anesthesiology. 75: A585-A585. DOI: 10.1097/00000542-199109001-00584  0.605
1989 Mackie KP, Nairn AC, Hampel G, Lam G, Jaffe EA. Thrombin and histamine stimulate the phosphorylation of elongation factor 2 in human umbilical vein endothelial cells. The Journal of Biological Chemistry. 264: 1748-53. PMID 2536373  0.42
1989 Mackie K, Sorkin B, Nairn A, Greengard P, Edelman G, Cunningham B. Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM The Journal of Neuroscience. 9: 1883-1896. DOI: 10.1523/Jneurosci.09-06-01883.1989  0.537
1986 Mackie K, Lai Y, Nairn AC, Greengard P, Pitt BR, Lazo JS. Protein phosphorylation in cultured endothelial cells. Journal of Cellular Physiology. 128: 367-74. PMID 3745280 DOI: 10.1002/jcp.1041280304  0.552
Low-probability matches (unlikely to be authored by this person)
2006 Guastalla A, Aramu S, Donna D, Cottone E, Campantico E, Mackie K, Wray S, Franzoni MF. A possible crosstalk between endocannabinoids and GnRH neurons: An immunohistochemical study in the amphibian brain Frontiers in Neuroendocrinology. 27: 31. DOI: 10.1016/J.Yfrne.2006.03.063  0.299
2020 Ao Z, Cai H, Havert DJ, Wu Z, Gong Z, Beggs JM, Mackie K, Guo F. One-stop Microfluidic Assembly of Human Brain Organoids to Model Prenatal Cannabis Exposure. Analytical Chemistry. PMID 32070103 DOI: 10.1021/acs.analchem.0c00205  0.296
2007 Mackie K. Understanding cannabinoid psychoactivity with mouse genetic models. Plos Biology. 5. PMID 17927451 DOI: 10.1371/Journal.Pbio.0050280  0.294
2009 Trimpin S, Herath TN, Inutan ED, Cernat SA, Miller JB, Mackie K, Walker JM. Field-free transmission geometry atmospheric pressure matrix-assisted laser desorption/ionization for rapid analysis of unadulterated tissue samples. Rapid Communications in Mass Spectrometry : Rcm. 23: 3023-7. PMID 19685478 DOI: 10.1002/Rcm.4213  0.293
2006 Tam J, Ofek O, Fride E, Ledent C, Gabet Y, M̈uller R, Zimmer A, Mackie K, Mechoulam R, Shohami E, Bab I. Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling Molecular Pharmacology. 70: 786-792. PMID 16772520 DOI: 10.1124/Mol.106.026435  0.293
2009 Patel S, Kingsley PJ, Mackie K, Marnett LJ, Winder DG. Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2699-709. PMID 19675536 DOI: 10.1038/Npp.2009.101  0.29
2017 Bluett RJ, Báldi R, Haymer A, Gaulden AD, Hartley ND, Parrish WP, Baechle J, Marcus DJ, Mardam-Bey R, Shonesy BC, Uddin MJ, Marnett LJ, Mackie K, Colbran RJ, Winder DG, et al. Endocannabinoid signalling modulates susceptibility to traumatic stress exposure. Nature Communications. 8: 14782. PMID 28348378 DOI: 10.1038/Ncomms14782  0.288
2015 Lovelace JW, Corches A, Vieira PA, Hiroto AS, Mackie K, Korzus E. An animal model of female adolescent cannabinoid exposure elicits a long-lasting deficit in presynaptic long-term plasticity. Neuropharmacology. 99: 242-255. PMID 25979486 DOI: 10.1016/J.Neuropharm.2015.04.034  0.287
2010 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T. Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13992-4007. PMID 20962221 DOI: 10.1523/Jneurosci.2126-10.2010  0.286
2009 Sun X, Wang H, Okabe M, Mackie K, Kingsley PJ, Marnett LJ, Cravatt BF, Dey SK. Genetic loss of Faah compromises male fertility in mice. Biology of Reproduction. 80: 235-42. PMID 18987328 DOI: 10.1095/Biolreprod.108.072736  0.281
2016 Leishman E, Mackie K, Luquet S, Bradshaw HB. Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain. Biochimica Et Biophysica Acta. 1861: 491-500. PMID 26956082 DOI: 10.1016/j.bbalip.2016.03.003  0.278
2020 Morozov YM, Mackie K, Rakic P. Cannabinoid Type 1 Receptor is Undetectable in Rodent and Primate Cerebral Neural Stem Cells but Participates in Radial Neuronal Migration. International Journal of Molecular Sciences. 21. PMID 33212822 DOI: 10.3390/ijms21228657  0.276
2015 Ballinger MD, Saito A, Abazyan B, Taniguchi Y, Huang CH, Ito K, Zhu X, Segal H, Jaaro-Peled H, Sawa A, Mackie K, Pletnikov MV, Kamiya A. Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory. Neurobiology of Disease. PMID 26093170 DOI: 10.1016/J.Nbd.2015.06.006  0.273
2020 László ZI, Lele Z, Zöldi M, Miczán V, Mógor F, Simon GM, Mackie K, Kacskovics I, Cravatt BF, Katona I. ABHD4-dependent developmental anoikis safeguards the embryonic brain. Nature Communications. 11: 4363. PMID 32868797 DOI: 10.1038/S41467-020-18175-4  0.273
2020 Burgdorf CE, Jing D, Yang R, Huang C, Hill MN, Mackie K, Milner TA, Pickel VM, Lee FS, Rajadhyaksha AM. Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice. Science Advances. 6: eaay1502. PMID 32095523 DOI: 10.1126/Sciadv.Aay1502  0.27
2002 Diana MA, Levenes C, Mackie K, Marty A. Short-term retrograde inhibition of GABAergic synaptic currents in rat Purkinje cells is mediated by endogenous cannabinoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 200-8. PMID 11756503  0.268
2020 Moussa-Tooks AB, Larson ER, Gimeno AF, Leishman E, Bartolomeo LA, Bradshaw HB, Green JT, O'Donnell BF, Mackie K, Hetrick WP. Long-Term Aberrations To Cerebellar Endocannabinoids Induced By Early-Life Stress. Scientific Reports. 10: 7236. PMID 32350298 DOI: 10.1038/S41598-020-64075-4  0.261
2015 Cherif H, Argaw A, Cécyre B, Bouchard A, Gagnon J, Javadi P, Desgent S, Mackie K, Bouchard JF. Role of GPR55 during Axon Growth and Target Innervation. Eneuro. 2. PMID 26730399 DOI: 10.1523/ENEURO.0011-15.2015  0.261
2019 Scheyer AF, Borsoi M, Wager-Miller J, Pelissier-Alicot AL, Murphy MN, Mackie K, Manzoni OJJ. Cannabinoid Exposure via Lactation in Rats Disrupts Perinatal Programming of the Gamma-Aminobutyric Acid Trajectory and Select Early-Life Behaviors. Biological Psychiatry. PMID 31653479 DOI: 10.1016/j.biopsych.2019.08.023  0.256
2018 Kasten CR, Zhang Y, Mackie K, Boehm SL. Short-Term Genetic Selection for Adolescent Locomotor Sensitivity to Delta9-Tetrahydrocannabinol (THC). Behavior Genetics. PMID 29550900 DOI: 10.1007/S10519-018-9894-2  0.253
2021 Hermes DJ, Yadav-Samudrala BJ, Xu C, Paniccia JE, Meeker RB, Armstrong ML, Reisdorph N, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Lysle DT, Fitting S. GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration. Experimental Neurology. 113699. PMID 33736974 DOI: 10.1016/j.expneurol.2021.113699  0.242
2013 Chen DH, Naydenov A, Blankman JL, Mefford HC, Davis M, Sul Y, Barloon AS, Bonkowski E, Wolff J, Matsushita M, Smith C, Cravatt BF, Mackie K, Raskind WH, Stella N, et al. Two novel mutations in ABHD12: expansion of the mutation spectrum in PHARC and assessment of their functional effects. Human Mutation. 34: 1672-8. PMID 24027063 DOI: 10.1002/Humu.22437  0.238
2006 Schuchmann S, Schmitz D, Rivera C, Vanhatalo S, Salmen B, Mackie K, Sipilä ST, Voipio J, Kaila K. Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis. Nature Medicine. 12: 817-23. PMID 16819552 DOI: 10.1038/Nm1422  0.237
2019 Moussa-Tooks A, Green J, Mackie K, Gimeno A, Larson E, Bradshaw H, Leishman E, O'Donnell B, Hetrick W. S196. Cerebellar Endocannabinoid Down-Regulation Accompanies Early Life Stress Induced Facilitation of Eyeblink Conditioning Biological Psychiatry. 85: S373. DOI: 10.1016/J.Biopsych.2019.03.947  0.235
2010 Alexander SP, Mackie K, Ross RA. Themed issue: cannabinoids. British Journal of Pharmacology. 160: 421-2. PMID 20590554 DOI: 10.1111/j.1476-5381.2010.00831.x  0.234
2018 Bara A, Manduca A, Bernabeu A, Borsoi M, Serviado M, Lassalle O, Murphy M, Wager-Miller J, Mackie K, Pelissier-Alicot A, Trezza V, Manzoni OJ. Author response: Sex-dependent effects of in utero cannabinoid exposure on cortical function Elife. DOI: 10.7554/Elife.36234.025  0.233
2016 Marshall DD, Inutan ED, Wang B, Liu CW, Thawoos S, Wager-Miller J, Mackie K, Trimpin S. A broad-based study on hyphenating new ionization technologies with MS/MS for PTM's and tissue characterization. Proteomics. PMID 27093917 DOI: 10.1002/Pmic.201500530  0.23
2020 Wager-Miller J, Green MM, Shafique H, Mackie K. Collection of Frozen Rodent Brain Regions for Downstream Analyses. Journal of Visualized Experiments. PMID 32391813 DOI: 10.3791/60474  0.228
1990 Mackie K, Lam AM, Slee TA, Butler SH, Jacobson L. Influence Of Intravenous Lidocaine On Brainstem And Somatosensory Evoked Potentials Anesthesia & Analgesia. 70. DOI: 10.1213/00000539-199002001-00253  0.224
1986 Mackie K, DePasquale M, Cserr HF. Increased permeability of a glial blood-brain barrier during acute hyperosmotic stress. American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 251. PMID 3789200 DOI: 10.1152/Ajpregu.1986.251.6.R1186  0.221
2014 Imperial L, Vithanarachchi SM, Wager-Miller J, Mackie K, Allen MJ, Trimpin S. A Novel Soft Ionization Process and Applications in Imaging Mass Spectrometry Biophysical Journal. 106: 1a. DOI: 10.1016/J.Bpj.2013.11.033  0.22
1991 Mackie K, Lam A. Epinephrine-containing test dose during beta-blockade. Journal of Clinical Monitoring and Computing. 7: 213-216. PMID 1679842 DOI: 10.1007/Bf01619262  0.219
2011 Inutan ED, Richards AL, Wager-Miller J, Mackie K, McEwen CN, Trimpin S. Laserspray ionization, a new method for protein analysis directly from tissue at atmospheric pressure with ultrahigh mass resolution and electron transfer dissociation Molecular and Cellular Proteomics. 10. PMID 20855542 DOI: 10.1074/Mcp.M110.000760  0.217
2016 Devereaux ZJ, Reynolds CA, Foley CD, Fischer JL, DeLeeuw JL, Wager-Miller J, Narayan SB, Mackie K, Trimpin S. Matrix-Assisted Ionization (MAI) on a Portable Mass Spectrometer: Analysis Directly from Biological and Synthetic Materials. Analytical Chemistry. PMID 26938428 DOI: 10.1021/Acs.Analchem.6B00304  0.217
2012 Richards AL, Lietz CB, Wager-Miller J, Mackie K, Trimpin S. Localization and imaging of gangliosides in mouse brain tissue sections by laserspray ionization inlet Journal of Lipid Research. 53: 1390-1398. PMID 22262808 DOI: 10.1194/Jlr.D019711  0.217
1983 Cserr HF, Bradbury MW, Mackie K, Moody EJ. Control of extracellular ions in skate brain during osmotic disturbances. The American Journal of Physiology. 245: R853-9. PMID 6660332 DOI: 10.1152/Ajpregu.1983.245.6.R853  0.214
2013 Inutan ED, Wager-Miller J, Narayan SB, Mackie K, Trimpin S. The potential for clinical applications using a new ionization method combined with ion mobility spectrometry-mass spectrometry International Journal For Ion Mobility Spectrometry. 16: 145-159. DOI: 10.1007/S12127-013-0131-7  0.213
2014 Lutomski CA, El-Baba TJ, Inutan ED, Manly CD, Wager-Miller J, Mackie K, Trimpin S. Transmission geometry laserspray ionization vacuum using an atmospheric pressure inlet. Analytical Chemistry. 86: 6208-13. PMID 24896880 DOI: 10.1021/Ac501788P  0.212
2015 Wang B, Dearring CL, Wager-Miller J, Mackie K, Trimpin S. Drug detection and quantification directly from tissue using novel ionization methods for mass spectrometry. European Journal of Mass Spectrometry (Chichester, England). 21: 201-10. PMID 26307700 DOI: 10.1255/Ejms.1338  0.211
2011 Richards AL, Lietz CB, Wager-Miller JB, Mackie K, Trimpin S. Imaging mass spectrometry in transmission geometry Rapid Communications in Mass Spectrometry. 25: 815-820. PMID 21337644 DOI: 10.1002/Rcm.4927  0.21
2020 Trimpin S, Marshall DD, Karki S, Madarshahian S, Hoang K, Meher AK, Pophristic M, Richards AL, Lietz CB, Fischer JL, Elia EA, Wang B, Pagnotti VS, Lutomski CA, El-Baba TJ, ... ... Mackie K, et al. An Overview of Biological Applications and Fundamentals of New Inlet and Vacuum Ionization Technologies. Rapid Communications in Mass Spectrometry : Rcm. e8829. PMID 32402102 DOI: 10.1002/Rcm.8829  0.21
2012 Inutan ED, Wager-Miller J, MacKie K, Trimpin S. Laserspray ionization imaging of multiply charged ions using a commercial vacuum MALDI ion source Analytical Chemistry. 84: 9079-9084. PMID 23009673 DOI: 10.1021/Ac301665H  0.202
2003 Mackie K. Understanding Marijuana: A New Look at the Scientific Evidence Nature Medicine. 9: 255-255. DOI: 10.1038/Nm0303-255  0.198
2021 Ao Z, Cai H, Wu Z, Song S, Karahan H, Kim B, Lu HC, Kim J, Mackie K, Guo F. Tubular human brain organoids to model microglia-mediated neuroinflammation. Lab On a Chip. PMID 34021557 DOI: 10.1039/d1lc00030f  0.197
1990 Mackie K, Pavlin EG. Recurrent paralysis following piperacillin administration. Anesthesiology. 72: 561-562. PMID 1968729 DOI: 10.1097/00000542-199003000-00028  0.195
2014 O'Donnell BF, Mackie K. The mismatch negativity: a translational probe of auditory processing in cannabis users. Biological Psychiatry. 75: 428-9. PMID 24560430 DOI: 10.1016/j.biopsych.2014.01.015  0.185
2020 Zavala CA, Thomaz AC, Iyer V, Mackie K, Hohmann AG. Cannabinoid CB Receptor Activation Attenuates Fentanyl-Induced Respiratory Depression. Cannabis and Cannabinoid Research. PMID 33998863 DOI: 10.1089/can.2020.0059  0.185
2018 Leishman E, Manchanda M, Thelen R, Miller S, Mackie K, Bradshaw HB. Cannabidiol's Upregulation of -acyl Ethanolamines in the Central Nervous System Requires -acyl Phosphatidyl Ethanolamine-Specific Phospholipase D. Cannabis and Cannabinoid Research. 3: 228-241. PMID 30515459 DOI: 10.1089/can.2018.0031  0.18
1997 Baguley WA, Hay WT, Mackie KP, Cheney FW, Cullen BF. Cardiac dysrhythmias associated with the intravenous administration of ondansetron and metoclopramide. Anesthesia and Analgesia. 84: 1380-1. PMID 9174325 DOI: 10.1097/00000539-199706000-00038  0.177
2020 Wiese BM, Liktor-Busa E, Levine A, Couture SA, Nikas SP, Ji L, Liu Y, Mackie K, Makriyannis A, Largent-Milnes TM, Vanderah TW. Cannabinoid-2 Agonism with AM2301 Mitigates Morphine-Induced Respiratory Depression. Cannabis and Cannabinoid Research. PMID 33998869 DOI: 10.1089/can.2020.0076  0.175
2015 Reyes BAS, Heldt NA, Mackie K, Van Bockstaele EJ. Ultrastructural evidence for synaptic contacts between cortical noradrenergic afferents and endocannabinoid-synthesizing post-synaptic neurons Neuroscience. 303: 323-337. DOI: 10.1016/j.neuroscience.2015.07.009  0.167
2021 Schnakenberg Martin AM, Kim DJ, Newman SD, Cheng H, Hetrick WP, Mackie K, O'Donnell BF. Altered cerebellar-cortical resting-state functional connectivity in cannabis users. Journal of Psychopharmacology (Oxford, England). 2698811211019291. PMID 34034553 DOI: 10.1177/02698811211019291  0.161
2021 Ao Z, Cai H, Wu Z, Ott J, Wang H, Mackie K, Guo F. Controllable fusion of human brain organoids using acoustofluidics. Lab On a Chip. PMID 33514983 DOI: 10.1039/d0lc01141j  0.159
2023 Zarrow JE, Alli-Oluwafuyi AM, Youwakim CM, Kim K, Jenkins AN, Suero IC, Jones MR, Mashhadi Z, Mackie KP, Waterson AG, Doran AC, Sulikowski GA, Davies SS. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. Biorxiv : the Preprint Server For Biology. PMID 36747693 DOI: 10.1101/2023.01.25.525554  0.149
2020 Lee MT, Chen YH, Mackie K, Chiou LC. Median nerve stimulation as a non-pharmacological approach to bypass analgesic tolerance to morphine: a proof-of-concept study in mice. The Journal of Pain : Official Journal of the American Pain Society. PMID 33069869 DOI: 10.1016/j.jpain.2020.09.003  0.148
2013 Mackie K. Endocannabinoid-mediated synaptic plasticity Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders. 11-24. DOI: 10.1007/978-1-4614-7940-6_2  0.14
2019 Moussa-Tooks A, Mackie K, Green J, Bartolomeo L, Gimeno A, Larson E, Bradshaw H, Leishman E, O’Donnell B, Hetrick W. 3004 Effects of Early Life Stress on Adult Behavioral and Neural Outcomes in Rats Journal of Clinical and Translational Science. 3: 9-10. DOI: 10.1017/cts.2019.26  0.137
2010 Massa F, Mancini G, Schmidt H, Steindel F, Mackie K, Angioni C, Oliet SHR, Geisslinger G, Lutz B. Alterations in the hippocampal endocannabinoid system in diet-induced obese mice (Journal of Neuroscience (2010) (6273-6281)) Journal of Neuroscience. 30.  0.088
2020 Chen HT, Mackie K. Adolescent Δ-Tetrahydrocannabinol Exposure Selectively Impairs Working Memory but Not Several Other mPFC-Mediated Behaviors. Frontiers in Psychiatry. 11: 576214. PMID 33262712 DOI: 10.3389/fpsyt.2020.576214  0.086
2017 Murphy M, Mills S, Winstone J, Leishman E, Wager-Miller J, Bradshaw H, Mackie K. Chronic Adolescent Δ(9)-Tetrahydrocannabinol Treatment of Male Mice Leads to Long-Term Cognitive and Behavioral Dysfunction, Which Are Prevented by Concurrent Cannabidiol Treatment. Cannabis and Cannabinoid Research. 2: 235-246. PMID 29098186 DOI: 10.1089/can.2017.0034  0.078
2021 Cai H, Ao Z, Wu Z, Song S, Mackie K, Guo F. Intelligent acoustofluidics enabled mini-bioreactors for human brain organoids. Lab On a Chip. PMID 33955446 DOI: 10.1039/d1lc00145k  0.068
2014 Lutomski CA, El-Baba TJ, Inutan ED, Manly CD, Wager-Miller J, Mackie K, Trimpin S. Transmission geometry laserspray ionization vacuum using an atmospheric pressure inlet Analytical Chemistry. 86: 6208-6213. DOI: 10.1021/ac501788p  0.022
2009 Mackie KP. Accelerated high water corrosion Concrete Repair, Rehabilitation and Retrofitting Ii - Proceedings of the 2nd International Conference On Concrete Repair, Rehabilitation and Retrofitting, Iccrrr. 257-258.  0.01
2000 Mackie KP. The practice of drydocking ships Dock and Harbour Authority. 81: 7-13.  0.01
2000 Mackie KP. The practice of dry docking ships Dock and Harbour Authority. 80: 98.  0.01
1995 Mackie KP. The Viskor System for the painting of marine structures Corrosion & Coatings South Africa. 22: 4-10.  0.01
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