Jeffrey M. Leiden - Publications

Affiliations: 
University of Chicago, Chicago, IL 

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2003 Pai SY, Truitt ML, Ting CN, Leiden JM, Glimcher LH, Ho IC. Critical roles for transcription factor GATA-3 in thymocyte development. Immunity. 19: 863-75. PMID 14670303 DOI: 10.1016/S1074-7613(03)00328-5  1
2003 Zhu W, Lepore JJ, Saba S, Joseph S, Link MS, Homoud MK, Estes NAM, Wang PJ, Leiden JM. Cardiac electrophysiologic abnormalities in the CREBA133 transgenic mouse model of idiopathic dilated cardiomyopathy Journal of Cardiovascular Electrophysiology. 14: 982-989. PMID 12950544 DOI: 10.1046/j.1540-8167.2003.02002.x  1
2003 Harding HP, Zhang Y, Zeng H, Novoa I, Lu PD, Calfon M, Sadri N, Yun C, Popko B, Paules R, Stojdl DF, Bell JC, Hettmann T, Leiden JM, Ron D. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Molecular Cell. 11: 619-33. PMID 12667446 DOI: 10.1016/S1097-2765(03)00105-9  1
2003 Hettmann T, Opferman JT, Leiden JM, Ashton-Rickardt PG. A critical role for NF-kappaB transcription factors in the development of CD8+ memory-phenotype T cells. Immunology Letters. 85: 297-300. PMID 12663146 DOI: 10.1016/S0165-2478(02)00260-2  1
2002 Eckhart AD, Fentzke RC, Lepore J, Lang R, Lin H, Lefkowitz RJ, Koch WJ, Leiden JM. Inhibition of betaARK1 restores impaired biochemical beta-adrenergic receptor responsiveness but does not rescue CREB(A133) induced cardiomyopathy. Journal of Molecular and Cellular Cardiology. 34: 669-77. PMID 12054854 DOI: 10.1006/jmcc.2002.2007  1
2001 Wolska BM, Vijayan K, Arteaga GM, Konhilas JP, Phillips RM, Kim R, Naya T, Leiden JM, Martin AF, de Tombe PP, Solaro RJ. Expression of slow skeletal troponin I in adult transgenic mouse heart muscle reduces the force decline observed during acidic conditions. The Journal of Physiology. 536: 863-70. PMID 11691878 DOI: 10.1111/j.1469-7793.2001.00863.x  1
2001 Buckley AF, Kuo CT, Leiden JM. Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway. Nature Immunology. 2: 698-704. PMID 11477405 DOI: 10.1038/90633  1
2001 Williams KL, Nanda I, Lyons GE, Kuo CT, Schmid M, Leiden JM, Kaplan MH, Taparowsky EJ. Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus. European Journal of Immunology. 31: 1620-7. PMID 11466704 DOI: 10.1002/1521-4141(200105)31:5<1620::AID-IMMU1620>3.0.CO;2-3  1
2001 Moawad J, Meyerson SL, Refai D, Skelly CL, Leiden JM, Schwartz LB. Adenoviral-mediated gene transfer in human and animal vein grafts using clinically relevant exposure times, pressures, and viral concentrations. Annals of Vascular Surgery. 15: 367-73. PMID 11414089 DOI: 10.1007/s100160010081  1
2001 Huggins GS, Bacani CJ, Boltax J, Aikawa R, Leiden JM. Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter. The Journal of Biological Chemistry. 276: 28029-36. PMID 11382775 DOI: 10.1074/jbc.M103577200  1
2001 Kentish JC, McCloskey DT, Layland J, Palmer S, Leiden JM, Martin AF, Solaro RJ. Phosphorylation of troponin I by protein kinase A accelerates relaxation and crossbridge cycle kinetics in mouse ventricular muscle. Circulation Research. 88: 1059-65. PMID 11375276  1
2001 Collins KA, Korcarz CE, Shroff SG, Bednarz JE, Fentzke RC, Lin H, Leiden JM, Lang RM. Accuracy of echocardiographic estimates of left ventricular mass in mice. American Journal of Physiology. Heart and Circulatory Physiology. 280: H1954-62. PMID 11299194  1
2001 Fentzke RC, Korcarz CE, Shroff SG, Lin H, Leiden JM, Lang RM. The left ventricular stress-velocity relation in transgenic mice expressing a dominant negative CREB transgene in the heart. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 14: 209-18. PMID 11241017 DOI: 10.1067/mje.2001.111473  1
2001 Kaji EH, Leiden JM. Gene and stem cell therapies. Jama. 285: 545-50. PMID 11176856  1
2000 Nakamura K, Ahmed M, Barr E, Leiden JM, Kang UJ. The localization and functional contribution of striatal aromatic L-amino acid decarboxylase to L-3,4-dihydroxyphenylalanine decarboxylation in rodent parkinsonian models. Cell Transplantation. 9: 567-76. PMID 11144954  1
2000 Hettmann T, Leiden JM. NF-kappa B is required for the positive selection of CD8+ thymocytes. Journal of Immunology (Baltimore, Md. : 1950). 165: 5004-10. PMID 11046028  1
2000 Tong Q, Dalgin G, Xu H, Ting CN, Leiden JM, Hotamisligil GS. Function of GATA transcription factors in preadipocyte-adipocyte transition. Science (New York, N.Y.). 290: 134-8. PMID 11021798 DOI: 10.1126/science.290.5489.134  1
2000 Marshall DJ, Palasis M, Lepore JJ, Leiden JM. Biocompatibility of cardiovascular gene delivery catheters with adenovirus vectors: an important determinant of the efficiency of cardiovascular gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 423-9. PMID 10933963 DOI: 10.1006/mthe.2000.0059  1
2000 Arteaga GM, Palmiter KA, Leiden JM, Solaro RJ. Attenuation of length dependence of calcium activation in myofilaments of transgenic mouse hearts expressing slow skeletal troponin I. The Journal of Physiology. 526: 541-9. PMID 10922006  1
2000 Spencer KT, Collins K, Korcarz C, Fentzke R, Lang RM, Leiden JM. Effects of exercise training on LV performance and mortality in a murine model of dilated cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 279: H210-5. PMID 10899058  1
2000 Svensson EC, Huggins GS, Lin H, Clendenin C, Jiang F, Tufts R, Dardik FB, Leiden JM. A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. Nature Genetics. 25: 353-6. PMID 10888889 DOI: 10.1038/77146  1
2000 Hettmann T, Barton K, Leiden JM. Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor. Developmental Biology. 222: 110-23. PMID 10885750 DOI: 10.1006/dbio.2000.9699  1
2000 Leiden JM. Human gene therapy: the good, the bad, and the ugly. Circulation Research. 86: 923-5. PMID 10807862  1
2000 Svensson EC, Huggins GS, Dardik FB, Polk CE, Leiden JM. A functionally conserved N-terminal domain of the friend of GATA-2 (FOG-2) protein represses GATA4-dependent transcription. The Journal of Biological Chemistry. 275: 20762-9. PMID 10801815 DOI: 10.1074/jbc.M001522200  1
2000 Morrisey EE, Musco S, Chen MY, Lu MM, Leiden JM, Parmacek MS. The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm. The Journal of Biological Chemistry. 275: 19949-54. PMID 10779506 DOI: 10.1074/jbc.M001331200  1
2000 Walunas TL, Wang B, Wang CR, Leiden JM. Cutting edge: the Ets1 transcription factor is required for the development of NK T cells in mice. Journal of Immunology (Baltimore, Md. : 1950). 164: 2857-60. PMID 10706669  1
1999 Schober SL, Kuo CT, Schluns KS, Lefrancois L, Leiden JM, Jameson SC. Expression of the transcription factor lung Krüppel-like factor is regulated by cytokines and correlates with survival of memory T cells in vitro and in vivo. Journal of Immunology (Baltimore, Md. : 1950). 163: 3662-7. PMID 10490960  1
1999 Macejak DG, Lin H, Webb S, Chase J, Jensen K, Jarvis TC, Leiden JM, Couture L. Adenovirus-mediated expression of a ribozyme to c-myb mRNA inhibits smooth muscle cell proliferation and neointima formation in vivo. Journal of Virology. 73: 7745-51. PMID 10438864  1
1999 Kuo CT, Leiden JM. Transcriptional regulation of T lymphocyte development and function. Annual Review of Immunology. 17: 149-87. PMID 10358756 DOI: 10.1146/annurev.immunol.17.1.149  1
1999 Schwartz LB, Moawad J, Svensson EC, Tufts RL, Meyerson SL, Baunoch D, Leiden JM. Adenoviral-mediated gene transfer of a constitutively active form of the retinoblastoma gene product attenuates neointimal thickening in experimental vein grafts. Journal of Vascular Surgery. 29: 874-81; discussion 8. PMID 10231639 DOI: 10.1016/S0741-5214(99)70215-6  1
1999 Fentzke RC, Buck SH, Patel JR, Lin H, Wolska BM, Stojanovic MO, Martin AF, Solaro RJ, Moss RL, Leiden JM. Impaired cardiomyocyte relaxation and diastolic function in transgenic mice expressing slow skeletal troponin I in the heart. The Journal of Physiology. 517: 143-57. PMID 10226156 DOI: 10.1111/j.1469-7793.1999.0143z.x  1
1999 Klinman DM, Conover J, Leiden JM, Rosenberg AS, Sechler JM. Safe and effective regulation of hematocrit by gene gun administration of an erythropoietin-encoding DNA plasmid. Human Gene Therapy. 10: 659-65. PMID 10094209 DOI: 10.1089/10430349950018733  1
1999 Leiden JM. Beating the odds: a cardiomyocyte cell line at last. The Journal of Clinical Investigation. 103: 591-2. PMID 10074473 DOI: 10.1172/JCI6471  1
1999 Mor-Avi V, Korcarz C, Fentzke RC, Lin H, Leiden JM, Lang RM. Quantitative evaluation of left ventricular function in a TransgenicMouse model of dilated cardiomyopathy with 2-dimensional contrast echocardiography. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 12: 209-14. PMID 10070185 DOI: 10.1016/S0894-7317(99)70137-9  1
1999 Svensson EC, Tufts RL, Polk CE, Leiden JM. Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 96: 956-61. PMID 9927675 DOI: 10.1073/pnas.96.3.956  1
1999 Svensson EC, Marshall DJ, Woodard K, Lin H, Jiang F, Chu L, Leiden JM. Efficient and stable transduction of cardiomyocytes after intramyocardial injection or intracoronary perfusion with recombinant adeno-associated virus vectors. Circulation. 99: 201-5. PMID 9892583  1
1999 Hettmann T, DiDonato J, Karin M, Leiden JM. An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis. The Journal of Experimental Medicine. 189: 145-58. PMID 9874571 DOI: 10.1084/jem.189.1.145  1
1998 Bassuk AG, Barton KP, Anandappa RT, Lu MM, Leiden JM. Expression pattern of the Ets-related transcription factor Elf-1. Molecular Medicine (Cambridge, Mass.). 4: 392-401. PMID 10780882  1
1998 Barton K, Muthusamy N, Fischer C, Ting CN, Walunas TL, Lanier LL, Leiden JM. The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity. 9: 555-63. PMID 9806641 DOI: 10.1016/S1074-7613(00)80638-X  1
1998 Muthusamy N, Leiden JM. A protein kinase C-, Ras-, and RSK2-dependent signal transduction pathway activates the cAMP-responsive element-binding protein transcription factor following T cell receptor engagement. The Journal of Biological Chemistry. 273: 22841-7. PMID 9712919 DOI: 10.1074/jbc.273.35.22841  1
1998 Marshall DJ, Leiden JM. Recent advances in skeletal-muscle-based gene therapy. Current Opinion in Genetics & Development. 8: 360-5. PMID 9691001 DOI: 10.1016/S0959-437X(98)80094-4  1
1998 Ma Y, Thornton S, Duwel LE, Boivin GP, Giannini EH, Leiden JM, Bluestone JA, Hirsch R. Inhibition of collagen-induced arthritis in mice by viral IL-10 gene transfer. Journal of Immunology (Baltimore, Md. : 1950). 161: 1516-24. PMID 9686619  1
1998 Lin H, Rathmell JC, Gray GS, Thompson CB, Leiden JM, Alegre ML. Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28. The Journal of Experimental Medicine. 188: 199-204. PMID 9653096 DOI: 10.1084/jem.188.1.199  1
1998 Fentzke RC, Korcarz CE, Lang RM, Lin H, Leiden JM. Dilated cardiomyopathy in transgenic mice expressing a dominant-negative CREB transcription factor in the heart. The Journal of Clinical Investigation. 101: 2415-26. PMID 9616213 DOI: 10.1172/JCI2950  1
1997 Fentzke RC, Korcarz CE, Shroff SG, Lin H, Sandelski J, Leiden JM, Lang RM. Evaluation of ventricular and arterial hemodynamics in anesthetized closed-chest mice. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 10: 915-25. PMID 9440069  1
1997 Kuo CT, Veselits ML, Leiden JM. LKLF and FasL expression: correctiona and clarification. Science (New York, N.Y.). 278: 788-9. PMID 9381186  1
1997 Kuo CT, Veselits ML, Barton KP, Lu MM, Clendenin C, Leiden JM. The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis. Genes & Development. 11: 2996-3006. PMID 9367982  1
1997 Leiden JM. The genetics of dilated cardiomyopathy--emerging clues to the puzzle. The New England Journal of Medicine. 337: 1080-1. PMID 9321539 DOI: 10.1056/NEJM199710093371511  1
1997 Kuo CT, Veselits ML, Leiden JM. LKLF: A transcriptional regulator of single-positive T cell quiescence and survival. Science (New York, N.Y.). 277: 1986-90. PMID 9302292 DOI: 10.1126/science.277.5334.1986  1
1997 Kim S, Lin H, Barr E, Chu L, Leiden JM, Parmacek MS. Transcriptional targeting of replication-defective adenovirus transgene expression to smooth muscle cells in vivo. The Journal of Clinical Investigation. 100: 1006-14. PMID 9276717 DOI: 10.1172/JCI119611  1
1997 Kuo CT, Morrisey EE, Anandappa R, Sigrist K, Lu MM, Parmacek MS, Soudais C, Leiden JM. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes & Development. 11: 1048-60. PMID 9136932  1
1997 Bassuk AG, Leiden JM. The role of Ets transcription factors in the development and function of the mammalian immune system. Advances in Immunology. 64: 65-104. PMID 9100980  1
1997 Bassuk AG, Anandappa RT, Leiden JM. Physical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cells. Journal of Virology. 71: 3563-73. PMID 9094628  1
1997 Morozov A, Shiyanov P, Barr E, Leiden JM, Raychaudhuri P. Accumulation of human papillomavirus type 16 E7 protein bypasses G1 arrest induced by serum deprivation and by the cell cycle inhibitor p21. Journal of Virology. 71: 3451-7. PMID 9094616  1
1997 Jordán J, Galindo MF, Prehn JH, Weichselbaum RR, Beckett M, Ghadge GD, Roos RP, Leiden JM, Miller RJ. p53 expression induces apoptosis in hippocampal pyramidal neuron cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1397-405. PMID 9006981  1
1997 Fentzke RC, Korcarz C, Sandelski J, Lin H, Leiden JM, Shroff SG, Lang RM. Arterial mechanical properties in closed-chest mice Journal of the American Society of Echocardiography. 10: 441.  1
1996 Chang MW, Leiden JM. Gene therapy for vascular proliferative disorders. Seminars in Interventional Cardiology : Siic. 1: 185-93. PMID 9552510  1
1996 Ting CN, Olson MC, Barton KP, Leiden JM. Transcription factor GATA-3 is required for development of the T-cell lineage. Nature. 384: 474-8. PMID 8945476 DOI: 10.1038/384474a0  1
1996 Leiden JM. Adenovirus-mediated gene transfer as an in vivo probe of lipoprotein metabolism. Circulation. 94: 2046-51. PMID 8901648  1
1996 Tripathy SK, Svensson EC, Black HB, Goldwasser E, Margalith M, Hobart PM, Leiden JM. Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector. Proceedings of the National Academy of Sciences of the United States of America. 93: 10876-80. PMID 8855275 DOI: 10.1073/pnas.93.20.10876  1
1996 Svensson EC, Tripathy SK, Leiden JM. Muscle-based gene therapy: realistic possibilities for the future. Molecular Medicine Today. 2: 166-72. PMID 8796879 DOI: 10.1016/1357-4310(96)88792-2  1
1996 Huynh Q, Butters CA, Leiden JM, Tobacman LS. Effects of cardiac thin filament Ca2+: statistical mechanical analysis of a troponin C site II mutant. Biophysical Journal. 70: 1447-55. PMID 8785301 DOI: 10.1016/S0006-3495(96)79704-7  1
1996 La Motte RN, Rubin MA, Barr E, Leiden JM, Bluestone JA, Mokyr MB. Therapeutic effectiveness of the immunity elicited by P815 tumor cells engineered to express the B7-2 costimulatory molecule. Cancer Immunology, Immunotherapy : Cii. 42: 161-9. PMID 8640844 DOI: 10.1007/s002620050266  1
1996 Tripathy SK, Black HB, Goldwasser E, Leiden JM. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nature Medicine. 2: 545-50. PMID 8616713  1
1996 Barton K, Muthusamy N, Chanyangam M, Fischer C, Clendenin C, Leiden JM. Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB. Nature. 379: 81-5. PMID 8538746 DOI: 10.1038/379081a0  1
1996 Lin H, Fentzke FT, Leiden JM. An experimental mouse model for cardiac ischemia and reperfusion study Faseb Journal. 10: A37.  1
1995 Soudais C, Bielinska M, Heikinheimo M, MacArthur CA, Narita N, Saffitz JE, Simon MC, Leiden JM, Wilson DB. Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro. Development (Cambridge, England). 121: 3877-88. PMID 8582296  1
1995 Ip HS, Wilson DB, Heikinheimo M, Leiden JM, Parmacek MS. The GATA-4 transcription factor transactivates the cardiac-specific troponin C promoter-enhancer in non-muscle cells. Advances in Experimental Medicine and Biology. 382: 117-24. PMID 8540389  1
1995 Chang MW, Ohno T, Gordon D, Lu MM, Nabel GJ, Nabel EG, Leiden JM. Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of the rat carotid artery. Molecular Medicine (Cambridge, Mass.). 1: 172-81. PMID 8529096  1
1995 John S, Reeves RB, Lin JX, Child R, Leiden JM, Thompson CB, Leonard WJ. Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins. Molecular and Cellular Biology. 15: 1786-96. PMID 7862168  1
1995 Chang MW, Barr E, Seltzer J, Jiang YQ, Nabel GJ, Nabel EG, Parmacek MS, Leiden JM. Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product. Science (New York, N.Y.). 267: 518-22. PMID 7824950  1
1995 McDonald KS, Field LJ, Parmacek MS, Soonpaa M, Leiden JM, Moss RL. Length dependence of Ca2+ sensitivity of tension in mouse cardiac myocytes expressing skeletal troponin C. The Journal of Physiology. 483: 131-9. PMID 7776227 DOI: 10.1113/jphysiol.1995.sp020573  1
1995 Chard PS, Jordán J, Marcuccilli CJ, Miller RJ, Leiden JM, Roos RP, Ghadge GD. Regulation of excitatory transmission at hippocampal synapses by calbindin D28k. Proceedings of the National Academy of Sciences of the United States of America. 92: 5144-8. PMID 7761464  1
1995 Leiden JM. Gene therapy--promise, pitfalls, and prognosis. The New England Journal of Medicine. 333: 871-3. PMID 7651480 DOI: 10.1056/NEJM199509283331310  1
1995 Bassuk AG, Leiden JM. A direct physical association between ETS and AP-1 transcription factors in normal human T cells. Immunity. 3: 223-37. PMID 7648395 DOI: 10.1016/1074-7613(95)90092-6  1
1995 Chang MW, Barr E, Lu MM, Barton K, Leiden JM. Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty. The Journal of Clinical Investigation. 96: 2260-8. PMID 7593612 DOI: 10.1172/JCI118281  1
1995 Muthusamy N, Barton K, Leiden JM. Defective activation and survival of T cells lacking the Ets-1 transcription factor. Nature. 377: 639-42. PMID 7566177 DOI: 10.1038/377639a0  1
1995 Ghadge GD, Roos RP, Kang UJ, Wollmann R, Fishman PS, Kalynych AM, Barr E, Leiden JM. CNS gene delivery by retrograde transport of recombinant replication-defective adenoviruses. Gene Therapy. 2: 132-7. PMID 7536617  1
1994 Barr E, Leiden JM. Somatic gene therapy for cardiovascular disease Recent advances. Trends in Cardiovascular Medicine. 4: 57-63. PMID 21244896 DOI: 10.1016/1050-1738(94)90010-8  1
1994 Wang CY, Bassuk AG, Boise LH, Thompson CB, Bravo R, Leiden JM. Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors. Molecular and Cellular Biology. 14: 1153-9. PMID 8289796  1
1994 Kenny JJ, Krebs FC, Hartle HT, Gartner AE, Chatton B, Leiden JM, Hoeffler JP, Weber PC, Wigdahl B. Identification of a second ATF/CREB-like element in the herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) promoter. Virology. 200: 220-35. PMID 8128624 DOI: 10.1006/viro.1994.1180  1
1994 Parmacek MS, Ip HS, Jung F, Shen T, Martin JF, Vora AJ, Olson EN, Leiden JM. A novel myogenic regulatory circuit controls slow/cardiac troponin C gene transcription in skeletal muscle. Molecular and Cellular Biology. 14: 1870-85. PMID 8114720  1
1994 Tripathy SK, Goldwasser E, Lu MM, Barr E, Leiden JM. Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus. Proceedings of the National Academy of Sciences of the United States of America. 91: 11557-61. PMID 7972101 DOI: 10.1073/pnas.91.24.11557  1
1994 Ip HS, Wilson DB, Heikinheimo M, Tang Z, Ting CN, Simon MC, Leiden JM, Parmacek MS. The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells. Molecular and Cellular Biology. 14: 7517-26. PMID 7935467  1
1994 Wurster AL, Siu G, Leiden JM, Hedrick SM. Elf-1 binds to a critical element in a second CD4 enhancer. Molecular and Cellular Biology. 14: 6452-63. PMID 7935370  1
1994 Leiden JM, Thompson CB. Transcriptional regulation of T-cell genes during T-cell development. Current Opinion in Immunology. 6: 231-7. PMID 7912079 DOI: 10.1016/0952-7915(94)90096-5  1
1994 Barr E, Carroll J, Kalynych AM, Tripathy SK, Kozarsky K, Wilson JM, Leiden JM. Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus. Gene Therapy. 1: 51-8. PMID 7584060  1
1994 Mao X, Miesfeldt S, Yang H, Leiden JM, Thompson CB. The FLI-1 and chimeric EWS-FLI-1 oncoproteins display similar DNA binding specificities. The Journal of Biological Chemistry. 269: 18216-22. PMID 7517940  1
1993 Wang CY, Petryniak B, Thompson CB, Kaelin WG, Leiden JM. Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein. Science (New York, N.Y.). 260: 1330-5. PMID 8493578  1
1993 Leiden JM. Transcriptional regulation of T cell receptor genes. Annual Review of Immunology. 11: 539-70. PMID 8476572 DOI: 10.1146/annurev.iy.11.040193.002543  1
1993 Boise LH, Petryniak B, Mao X, June CH, Wang CY, Lindsten T, Bravo R, Kovary K, Leiden JM, Thompson CB. The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB. Molecular and Cellular Biology. 13: 1911-9. PMID 8441422  1
1993 Metzger JM, Parmacek MS, Barr E, Pasyk K, Lin WI, Cochrane KL, Field LJ, Leiden JM. Skeletal troponin C reduces contractile sensitivity to acidosis in cardiac myocytes from transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 9036-40. PMID 8415650  1
1993 Miesfeldt S, Kim S, Hanson CA, Bohjanen PR, Leiden JM, Crist WM, Carroll AJ, Thompson CB. DNA fragments of altered electrophoretic mobility in leukemia samples can arise from double-strand DNA breaks at nuclease hypersensitive sites of active genes. Cancer Genetics and Cytogenetics. 68: 34-41. PMID 8330281 DOI: 10.1016/0165-4608(93)90071-S  1
1992 Wells RG, Lee WS, Kanai Y, Leiden JM, Hediger MA. The 4F2 antigen heavy chain induces uptake of neutral and dibasic amino acids in Xenopus oocytes. The Journal of Biological Chemistry. 267: 15285-8. PMID 1639774  1
1992 Gulati J, Leiden JM, Parmacek MS. Length-sensing function of troponin C and Starling's law of the heart [5] Circulation. 85: 1954-1955. PMID 1572054  1
1992 Parmacek MS, Vora AJ, Shen T, Barr E, Jung F, Leiden JM. Identification and characterization of a cardiac-specific transcriptional regulatory element in the slow/cardiac troponin C gene. Molecular and Cellular Biology. 12: 1967-76. PMID 1569934  1
1992 Wang CY, Petryniak B, Ho IC, Thompson CB, Leiden JM. Evolutionarily conserved Ets family members display distinct DNA binding specificities. The Journal of Experimental Medicine. 175: 1391-9. PMID 1569404  1
1992 Thompson CB, Wang CY, Ho IC, Bohjanen PR, Petryniak B, June CH, Miesfeldt S, Zhang L, Nabel GJ, Karpinski B, Leiden JM. cis-Acting Sequences Required for Inducible Interleukin-2 Enhancer Function Bind a Novel Ets-Related Protein, Elf-1 Molecular and Cellular Biology. 12: 1043-1053. PMID 1545787  1
1992 Karpinski BA, Morle GD, Huggenvik J, Uhler MD, Leiden JM. Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element. Proceedings of the National Academy of Sciences of the United States of America. 89: 4820-4. PMID 1534408  1
1992 Leiden JM. Transcriptional regulation during T-cell development: the alpha TCR gene as a molecular model. Immunology Today. 13: 22-30. PMID 1531412 DOI: 10.1016/0167-5699(92)90200-Q  1
1992 Leiden JM, Wang CY, Petryniak B, Markovitz DM, Nabel GJ, Thompson CB. A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells. Journal of Virology. 66: 5890-7. PMID 1527846  1
1992 Turka LA, Linsley PS, Lin H, Brady W, Leiden JM, Wei RQ, Gibson ML, Zheng XG, Myrdal S, Gordon D. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proceedings of the National Academy of Sciences of the United States of America. 89: 11102-5. PMID 1332070  1
1992 Barr E, Lin H, Parmacek MS, Leiden JM. Direct gene transfer into cardiac myocytes in vivo Methods. 4: 169-176. DOI: 10.1016/1046-2023(92)90049-E  1
1991 Leinwand LA, Leiden JM. Gene transfer into cardiac myocytes in vivo. Trends in Cardiovascular Medicine. 1: 271-6. PMID 21239293 DOI: 10.1016/1050-1738(91)90042-D  1
1991 Barr E, Leiden JM. Systemic delivery of recombinant proteins by genetically modified myoblasts. Science (New York, N.Y.). 254: 1507-9. PMID 1962212  1
1991 Parmacek MS, Leiden JM. Structure, function, and regulation of troponin C. Circulation. 84: 991-1003. PMID 1884474  1
1991 Ho IC, Vorhees P, Marin N, Oakley BK, Tsai SF, Orkin SH, Leiden JM. Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene. The Embo Journal. 10: 1187-92. PMID 1827068  1
1990 Parmacek MS, Bengur AR, Vora AJ, Leiden JM. The structure and regulation of expression of the murine fast skeletal troponin C gene. Identification of a developmentally regulated, muscle-specific transcriptional enhancer. The Journal of Biological Chemistry. 265: 15970-6. PMID 2394755  1
1990 Ho IC, Leiden JM. Regulation of the human T-cell receptor alpha gene enhancer: multiple ubiquitous and T-cell-specific nuclear proteins interact with four hypomethylated enhancer elements. Molecular and Cellular Biology. 10: 4720-7. PMID 2388624  1
1990 Ho IC, Bhat NK, Gottschalk LR, Lindsten T, Thompson CB, Papas TS, Leiden JM. Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancer. Science (New York, N.Y.). 250: 814-8. PMID 2237431  1
1990 Tjoelker LW, Carlson LM, Lee K, Lahti J, McCormack WT, Leiden JM, Chen CL, Cooper MD, Thompson CB. Evolutionary conservation of antigen recognition: the chicken T-cell receptor beta chain. Proceedings of the National Academy of Sciences of the United States of America. 87: 7856-60. PMID 2236002  1
1990 Ho IC, Leiden JM. The T alpha 2 nuclear protein binding site from the human T cell receptor alpha enhancer functions as both a T cell-specific transcriptional activator and repressor. The Journal of Experimental Medicine. 172: 1443-9. PMID 2230652  1
1990 Lin H, Parmacek MS, Morle G, Bolling S, Leiden JM. Expression of recombinant genes in myocardium in vivo after direct injection of DNA. Circulation. 82: 2217-21. PMID 2173647  1
1990 Gottschalk LR, Leiden JM. Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genes. Molecular and Cellular Biology. 10: 5486-95. PMID 2144610  1
1989 Parmacek MS, Karpinski BA, Gottesdiener KM, Thompson CB, Leiden JM. Structure, expression and regulation of the murine 4F2 heavy chain. Nucleic Acids Research. 17: 1915-31. PMID 2928113 DOI: 10.1093/nar/17.5.1915  1
1989 Leiden JM, Yang LH, Morle GD, June CH, Lindsten T, Thompson CB, Karpinski B. The 4F2 heavy chain gene: a molecular model of inducible gene expression in human T cells. Journal of Autoimmunity. 2: 67-79. PMID 2789062 DOI: 10.1016/0896-8411(89)90118-2  1
1989 Ho IC, Yang LH, Morle G, Leiden JM. A T-cell-specific transcriptional enhancer element 3' of C alpha in the human T-cell receptor alpha locus. Proceedings of the National Academy of Sciences of the United States of America. 86: 6714-8. PMID 2788889  1
1989 Karpinski BA, Yang LH, Cacheris P, Morle GD, Leiden JM. The first intron of the 4F2 heavy-chain gene contains a transcriptional enhancer element that binds multiple nuclear proteins. Molecular and Cellular Biology. 9: 2588-97. PMID 2761540  1
1989 Parmacek MS, Leiden JM. Structure and expression of the murine slow/cardiac troponin C gene. The Journal of Biological Chemistry. 264: 13217-25. PMID 2753913  1
1989 June CH, Jackson KM, Ledbetter JA, Leiden JM, Lindsten T, Thompson CB. Two distinct mechanisms of interleukin-2 gene expression in human T lymphocytes. Journal of Autoimmunity. 2: 55-65. PMID 2550020 DOI: 10.1016/0896-8411(89)90117-0  1
1989 Leiden JM, Karpinski BA, Gottschalk L, Kornbluth J. Susceptibility to natural killer cell-mediated cytolysis is independent of the level of target cell class I HLA expression. Journal of Immunology (Baltimore, Md. : 1950). 142: 2140-7. PMID 2493507  1
1989 Thompson CB, Lindsten T, Ledbetter JA, Kunkel SL, Young HA, Emerson SG, Leiden JM, June CH. CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines. Proceedings of the National Academy of Sciences of the United States of America. 86: 1333-7. PMID 2465550  1
1988 Leiden JM, Gottesdiener KM, Quertermous T, Coury L, Bray RA, Gottschalk L, Gebel H, Seidman JG, Strominger JL, Landay AL. T-cell receptor gene rearrangement and expression in human natural killer cells: natural killer activity is not dependent on the rearrangement and expression of T-cell receptor alpha, beta, or gamma genes. Immunogenetics. 27: 231-8. PMID 3346041 DOI: 10.1007/BF00376117  1
1988 Lindsten T, June CH, Thompson CB, Leiden JM. Regulation of 4F2 heavy-chain gene expression during normal human T-cell activation can be mediated by multiple distinct molecular mechanisms. Molecular and Cellular Biology. 8: 3820-6. PMID 3265471  1
1988 Gottesdiener KM, Karpinski BA, Lindsten T, Strominger JL, Jones NH, Thompson CB, Leiden JM. Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte activation. Molecular and Cellular Biology. 8: 3809-19. PMID 3265470  1
1987 Quackenbush E, Clabby M, Gottesdiener KM, Barbosa J, Jones NH, Strominger JL, Speck S, Leiden JM. Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth. Proceedings of the National Academy of Sciences of the United States of America. 84: 6526-30. PMID 3476959  1
1986 Leiden JM, Dialynas DP, Duby AD, Murre C, Seidman J, Strominger JL. Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment. Molecular and Cellular Biology. 6: 3207-14. PMID 3491297  1
1986 Leiden JM, Strominger JL. Generation of diversity of the beta chain of the human T-lymphocyte receptor for antigen. Proceedings of the National Academy of Sciences of the United States of America. 83: 4456-60. PMID 3487088  1
1986 Dialynas DP, Murre C, Quertermous T, Boss JM, Leiden JM, Seidman JG, Strominger JL. Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. Proceedings of the National Academy of Sciences of the United States of America. 83: 2619-23. PMID 3458221  1
1986 Leiden JM, Fraser JD, Strominger JL. The complete primary structure of the T-cell receptor genes from an alloreactive cytotoxic human T-lymphocyte clone. Immunogenetics. 24: 17-23. PMID 2426193 DOI: 10.1007/BF00372293  1
1980 Leiden JM, Frenkel N, Sabourin D, Davidson RL. Mapping of the herpes simplex virus DNA sequences present in herpes simplex virus type-1 thymidine kinase-transformed cells. Somatic Cell Genetics. 6: 789-98. PMID 6255619 DOI: 10.1007/BF01538977  1
1980 Leiden JM, Frenkel N, Rapp F. Identification of the herpes simplex virus DNA sequences present in six herpes simplex virus thymidine kinase-transformed mouse cell lines. Journal of Virology. 33: 272-85. PMID 6245232  1
1978 Leiden JM, Frenkel N, Polacek D, Rapp F. Mapping of the herpes simplex virus DNA sequences in three herpes simplex virus thymidine kinase-transformed cell lines. Iarc Scientific Publications. 473-88. PMID 221351  1
1976 Leiden JM, Buttyan R, Spear PG. Herpes simplex virus gene expression in transformed cells. I. Regulation of the viral thymidine kinase gene in transformed L cells by products of superinfecting virus. Journal of Virology. 20: 413-24. PMID 185425  1
1975 Spear PG, Leiden JM. Regulation of herpesvirus gene expression in biochemical transformed cells: investigations of virus-specified regulatory functions. Bibliotheca Haematologica. 53-8. PMID 183722  1
Show low-probability matches.