Andrew Josef Ewald - Publications

Affiliations: 
2003 California Institute of Technology, Pasadena, CA 

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Padmanaban V, Grasset EM, Neumann NM, Fraser AK, Henriet E, Matsui W, Tran PT, Cheung KJ, Georgess D, Ewald AJ. Organotypic culture assays for murine and human primary and metastatic-site tumors. Nature Protocols. PMID 32690957 DOI: 10.1038/s41596-020-0335-3  0.44
2020 Hasnain Z, Fraser AK, Georgess D, Choi A, Macklin P, Bader JS, Peyton SR, Ewald AJ, Newton PK. OrgDyn: Feature and model based characterization of spatial and temporal organoid dynamics. Bioinformatics (Oxford, England). PMID 32091578 DOI: 10.1093/bioinformatics/btaa096  0.44
2019 Yang J, Duan X, Fraser AK, Choudhury MI, Ewald AJ, Li R, Sun SX. Microscale pressure measurements based on an immiscible fluid/fluid interface. Scientific Reports. 9: 20044. PMID 31882951 DOI: 10.1038/s41598-019-56573-x  0.44
2019 Hickey JW, Dong Y, Chung JW, Salathe SF, Pruitt HC, Li X, Chang C, Fraser AK, Bessell CA, Ewald AJ, Gerecht S, Mao HQ, Schneck JP. Engineering an Artificial T-Cell Stimulating Matrix for Immunotherapy. Advanced Materials (Deerfield Beach, Fla.). e1807359. PMID 30968468 DOI: 10.1002/adma.201807359  0.44
2016 Teo WW, Merino VF, Cho S, Korangath P, Liang X, Wu RC, Neumann NM, Ewald AJ, Sukumar S. HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24. Oncogene. PMID 27157614 DOI: 10.1038/onc.2016.95  0.36
2016 Huebner RJ, Neumann NM, Ewald AJ. Mammary epithelial tubes elongate through MAPK-dependent coordination of cell migration. Development (Cambridge, England). PMID 26839364 DOI: 10.1242/dev.127944  0.36
2016 Cheung KJ, Padmanaban V, Silvestri V, Schipper K, Cohen JD, Fairchild AN, Gorin MA, Verdone JE, Pienta KJ, Bader JS, Ewald AJ. Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831077 DOI: 10.1073/pnas.1508541113  0.36
2016 Ellison D, Mugler A, Brennan MD, Lee SH, Huebner RJ, Shamir ER, Woo LA, Kim J, Amar P, Nemenman I, Ewald AJ, Levchenko A. Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26792522 DOI: 10.1073/pnas.1516503113  0.36
2015 Ewald AJ. An Arresting Story about Basement Membrane Invasion. Developmental Cell. 35: 143-4. PMID 26506303 DOI: 10.1016/j.devcel.2015.10.009  0.36
2015 Kim M, Shewan A, Ewald AJ, Werb Z, Mostov KE. P114RhoGEF governs cell motility and lumen formation during tubulogenesis via ROCK-myosin II pathway. Journal of Cell Science. PMID 26483385 DOI: 10.1242/jcs.172361  0.36
2015 Nguyen-Ngoc KV, Shamir ER, Huebner RJ, Beck JN, Cheung KJ, Ewald AJ. 3D culture assays of murine mammary branching morphogenesis and epithelial invasion. Methods in Molecular Biology (Clifton, N.J.). 1189: 135-62. PMID 25245692 DOI: 10.1007/978-1-4939-1164-6_10  0.36
2015 Ewald AJ. Quantitative real-time analysis of collective cancer invasion and dissemination Proceedings of Spie - the International Society For Optical Engineering. 9496. DOI: 10.1117/12.2191515  0.36
2015 Shamir ER, Ewald AJ. Adhesion in mammary development: Novel roles for E-cadherin in individual and collective cell migration Current Topics in Developmental Biology. 112: 353-382. DOI: 10.1016/bs.ctdb.2014.12.001  0.36
2014 Chapiro J, Sur S, Savic LJ, Ganapathy-Kanniappan S, Reyes J, Duran R, Thiruganasambandam SC, Moats CR, Lin M, Luo W, Tran PT, Herman JM, Semenza GL, Ewald AJ, Vogelstein B, et al. Systemic delivery of microencapsulated 3-bromopyruvate for the therapy of pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 6406-17. PMID 25326230 DOI: 10.1158/1078-0432.CCR-14-1271  0.36
2014 Bryant DM, Roignot J, Datta A, Overeem AW, Kim M, Yu W, Peng X, Eastburn DJ, Ewald AJ, Werb Z, Mostov KE. A molecular switch for the orientation of epithelial cell polarization. Developmental Cell. 31: 171-87. PMID 25307480 DOI: 10.1016/j.devcel.2014.08.027  0.36
2014 Shamir ER, Ewald AJ. Three-dimensional organotypic culture: Experimental models of mammalian biology and disease Nature Reviews Molecular Cell Biology. 15: 647-664. PMID 25237826 DOI: 10.1038/nrm3873  0.36
2014 Ewald AJ, Egeblad M. Cancer: Sugar-coated cell signalling Nature. 511: 298-299. PMID 25030162 DOI: 10.1038/nature13506  0.36
2014 Huebner RJ, Ewald AJ. Cellular foundations of mammary tubulogenesis. Seminars in Cell & Developmental Biology. 31: 124-31. PMID 24747369 DOI: 10.1016/j.semcdb.2014.04.019  0.36
2014 Cheung KJ, Ewald AJ. Invasive leader cells: Metastatic oncotarget Oncotarget. 5: 1390-1391. PMID 24727787  0.36
2014 Shamir ER, Pappalardo E, Jorgens DM, Coutinho K, Tsai WT, Aziz K, Auer M, Tran PT, Bader JS, Ewald AJ. Twist1-induced dissemination preserves epithelial identity and requires E-cadherin. The Journal of Cell Biology. 204: 839-56. PMID 24590176 DOI: 10.1083/jcb.201306088  0.36
2014 Chen Q, Zhang N, Gray RS, Li H, Ewald AJ, Zahnow CA, Pan D. A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis. Genes & Development. 28: 432-7. PMID 24589775 DOI: 10.1101/gad.233676.113  0.36
2014 Huebner RJ, Lechler T, Ewald AJ. Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells. Development (Cambridge, England). 141: 1085-94. PMID 24550116 DOI: 10.1242/dev.103333  0.36
2014 Cheung KJ, Ewald AJ. Illuminating breast cancer invasion: Diverse roles for cell-cell interactions Current Opinion in Cell Biology. 30: 99-111. DOI: 10.1016/j.ceb.2014.07.003  0.36
2013 Cheung KJ, Gabrielson E, Werb Z, Ewald AJ. Collective invasion in breast cancer requires a conserved basal epithelial program. Cell. 155: 1639-51. PMID 24332913 DOI: 10.1016/j.cell.2013.11.029  0.36
2013 Beck JN, Singh A, Rothenberg AR, Elisseeff JH, Ewald AJ. The independent roles of mechanical, structural and adhesion characteristics of 3D hydrogels on the regulation of cancer invasion and dissemination. Biomaterials. 34: 9486-95. PMID 24044993 DOI: 10.1016/j.biomaterials.2013.08.077  0.36
2013 Ewald AJ. Isolation of mouse mammary organoids for long-term time-lapse imaging Cold Spring Harbor Protocols. 8: 130-133. PMID 23378653 DOI: 10.1101/pdb.prot072892  0.36
2013 Ewald AJ. Practical considerations for long-term time-lapse imaging of epithelial morphogenesis in three-dimensional organotypic cultures Cold Spring Harbor Protocols. 8: 100-117. PMID 23378652 DOI: 10.1101/pdb.top072884  0.36
2013 Nguyen-Ngoc KV, Ewald AJ. Mammary ductal elongation and myoepithelial migration are regulated by the composition of the extracellular matrix Journal of Microscopy. 251: 212-223. DOI: 10.1111/jmi.12017  0.36
2012 Nguyen-Ngoc KV, Cheung KJ, Brenot A, Shamir ER, Gray RS, Hines WC, Yaswen P, Werb Z, Ewald AJ. ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium. Proceedings of the National Academy of Sciences of the United States of America. 109: E2595-604. PMID 22923691 DOI: 10.1073/pnas.1212834109  0.36
2012 Nakasone ES, Askautrud HA, Kees T, Park JH, Plaks V, Ewald AJ, Fein M, Rasch MG, Tan YX, Qiu J, Park J, Sinha P, Bissell MJ, Frengen E, Werb Z, et al. Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. Cancer Cell. 21: 488-503. PMID 22516258 DOI: 10.1016/j.ccr.2012.02.017  0.36
2012 Ewald AJ, Huebner RJ, Palsdottir H, Lee JK, Perez MJ, Jorgens DM, Tauscher AN, Cheung KJ, Werb Z, Auer M. Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium. Journal of Cell Science. 125: 2638-54. PMID 22344263 DOI: 10.1242/jcs.096875  0.36
2011 Ewald AJ, Werb Z, Egeblad M. Dynamic, long-term in vivo imaging of tumor-stroma interactions in mouse models of breast cancer using spinning-disk confocal microscopy. Cold Spring Harbor Protocols. 2011: pdb.top97. PMID 21285277 DOI: 10.1101/pdb.top97  0.36
2011 Ewald AJ, Werb Z, Egeblad M. Monitoring of vital signs for long-term survival of mice under anesthesia. Cold Spring Harbor Protocols. 2011: pdb.prot5563. PMID 21285263 DOI: 10.1101/pdb.prot5563  0.36
2011 Ewald AJ, Werb Z, Egeblad M. Preparation of mice for long-term intravital imaging of the mammary gland. Cold Spring Harbor Protocols. 2011: pdb.prot5562. PMID 21285262 DOI: 10.1101/pdb.prot5562  0.36
2010 Gray RS, Cheung KJ, Ewald AJ. Cellular mechanisms regulating epithelial morphogenesis and cancer invasion Current Opinion in Cell Biology. 22: 640-650. PMID 20832275 DOI: 10.1016/j.ceb.2010.08.019  0.36
2010 Bhise NS, Gray RS, Sunshine JC, Htet S, Ewald AJ, Green JJ. The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures. Biomaterials. 31: 8088-96. PMID 20674001 DOI: 10.1016/j.biomaterials.2010.07.023  0.36
2010 Andrew DJ, Ewald AJ. Morphogenesis of epithelial tubes: Insights into tube formation, elongation, and elaboration. Developmental Biology. 341: 34-55. PMID 19778532 DOI: 10.1016/j.ydbio.2009.09.024  0.36
2008 Egeblad M, Ewald AJ, Askautrud HA, Truitt ML, Welm BE, Bainbridge E, Peeters G, Krummel MF, Werb Z. Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy. Disease Models & Mechanisms. 1: 155-67; discussion 1. PMID 19048079 DOI: 10.1242/dmm.000596  0.36
2008 Ewald AJ, Wallingford J. Vertebrate Gastrulation: Separation Is Sticky and Tense Current Biology. 18: R615-R617. PMID 18644340 DOI: 10.1016/j.cub.2008.06.016  0.36
2008 Lu P, Ewald AJ, Martin GR, Werb Z. Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis. Developmental Biology. 321: 77-87. PMID 18585375 DOI: 10.1016/j.ydbio.2008.06.005  0.36
2008 Ewald AJ, Brenot A, Duong M, Chan BS, Werb Z. Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Developmental Cell. 14: 570-81. PMID 18410732 DOI: 10.1016/j.devcel.2008.03.003  0.36
2008 Martín-Belmonte F, Yu W, Rodríguez-Fraticelli AE, Ewald AJ, Ewald A, Werb Z, Alonso MA, Mostov K. Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis. Current Biology : Cb. 18: 507-13. PMID 18394894 DOI: 10.1016/j.cub.2008.02.076  0.36
2008 Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, Ewald AJ, Pai SY, Ho IC, Werb Z. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell. 13: 141-52. PMID 18242514 DOI: 10.1016/j.ccr.2008.01.011  0.36
2008 Martín-Belmonte F, Yu W, Rodríguez-Fraticelli AE, Ewald AJ, Werb Z, Alonso MA, Mostov K. Cell-Polarity Dynamics Controls the Mechanism of Lumen Formation in Epithelial Morphogenesis (DOI:10.1016/j.cub.2008.02.076) Current Biology. 18: 1016. DOI: 10.1016/j.cub.2008.06.055  0.36
2007 Levin M, Ewald AJ, McMahon M, Werb Z, Mostov K. A model of intussusceptive angiogenesis. Novartis Foundation Symposium. 283: 37-42; discussion 42. PMID 18300412  0.36
2007 Fata JE, Mori H, Ewald AJ, Zhang H, Yao E, Werb Z, Bissell MJ. The MAPK(ERK-1,2) pathway integrates distinct and antagonistic signals from TGFalpha and FGF7 in morphogenesis of mouse mammary epithelium. Developmental Biology. 306: 193-207. PMID 17448457 DOI: 10.1016/j.ydbio.2007.03.013  0.36
2007 Yu W, Fang X, Ewald A, Wong K, Hunt CA, Werb Z, Matthay MA, Mostov K. Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis. Molecular Biology of the Cell. 18: 1693-700. PMID 17332496 DOI: 10.1091/mbc.E06-11-1052  0.36
2007 Page-McCaw A, Ewald AJ, Werb Z. Matrix metalloproteinases and the regulation of tissue remodelling. Nature Reviews. Molecular Cell Biology. 8: 221-33. PMID 17318226 DOI: 10.1038/nrm2125  0.36
2005 Tyszka JM, Ewald AJ, Wallingford JB, Fraser SE. New tools for visualization and analysis of morphogenesis in spherical embryos Developmental Dynamics. 234: 974-983. PMID 16193511 DOI: 10.1002/dvdy.20561  0.36
2005 Song S, Ewald AJ, Stallcup W, Werb Z, Bergers G. PDGFRβ+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival Nature Cell Biology. 7: 870-879. PMID 16113679 DOI: 10.1038/ncb1288  0.36
2004 Ewald AJ, Peyrot SM, Tyszka JM, Fraser SE, Wallingford JB. Regional requirements for Dishevelled signaling during Xenopus gastrulation: separable effects on blastopore closure, mesendoderm internalization and archenteron formation. Development (Cambridge, England). 131: 6195-209. PMID 15548584 DOI: 10.1242/dev.01542  0.36
2003 Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, Chan DC. Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. The Journal of Cell Biology. 160: 189-200. PMID 12527753 DOI: 10.1083/jcb.200211046  0.36
2002 Ewald AJ, McBride H, Reddington M, Fraser SE, Kerschmann R. Surface imaging microscopy, an automated method for visualizing whole embryo samples in three dimensions at high resolution. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 225: 369-75. PMID 12412023 DOI: 10.1002/dvdy.10169  0.36
2001 Wallingford JB, Ewald AJ, Harland RM, Fraser SE. Calcium signaling during convergent extension in Xenopus. Current Biology : Cb. 11: 652-61. PMID 11369228 DOI: 10.1016/S0960-9822(01)00201-9  0.36
1998 Strong RK, Bratt T, Cowland JB, Borregaard N, Wiberg FC, Ewald AJ. Expression, purification, crystallization and crystallographic characterization of dimeric and monomeric human neutrophil gelatinase associated lipocalin (NGAL) Acta Crystallographica Section D: Biological Crystallography. 54: 93-95. PMID 9761822 DOI: 10.1107/S0907444997010615  0.36
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