Rakesh Nagarajan, Ph.D. - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Axonal degeneration, peripheral neuropathy, Myelination, Schwann cell metabolism

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cayetano RDA, Park JH, Kang S, Kim SH. Food waste treatment in an anaerobic dynamic membrane bioreactor (AnDMBR): Performance monitoring and microbial community analysis. Bioresource Technology. 280: 158-164. PMID 30771570 DOI: 10.1016/j.biortech.2019.02.025  0.4
2019 Moon SW, Choi JS, Lee SH, Jung KS, Jung JY, Kang YA, Park MS, Kim YS, Chang J, Kim SY. Thoracic skeletal muscle quantification: low muscle mass is related with worse prognosis in idiopathic pulmonary fibrosis patients. Respiratory Research. 20: 35. PMID 30767787 DOI: 10.1186/s12931-019-1001-6  0.36
2016 Roy S, LaFramboise WA, Nikiforov YE, Nikiforova MN, Routbort MJ, Pfeifer J, Nagarajan R, Carter AB, Pantanowitz L. Next-Generation Sequencing Informatics. Archives of Pathology & Laboratory Medicine. PMID 26901284 DOI: 10.5858/arpa.2015-0507-RA  0.48
2015 Olfson E, Cottrell CE, Davidson NO, Gurnett CA, Heusel JW, Stitziel NO, Chen LS, Hartz S, Nagarajan R, Saccone NL, Bierut LJ. Identification of Medically Actionable Secondary Findings in the 1000 Genomes. Plos One. 10: e0135193. PMID 26332594 DOI: 10.1371/journal.pone.0135193  0.48
2015 McIntosh LD, Sharma MK, Mulvihill D, Gupta S, Juehne A, George B, Khot SB, Kaushal A, Watson MA, Nagarajan R. caTissue suite to OpenSpecimen: Developing an extensible, open source, web-based biobanking management system. Journal of Biomedical Informatics. PMID 26325296 DOI: 10.1016/j.jbi.2015.08.020  0.48
2015 Gargis AS, Kalman L, Bick DP, da Silva C, Dimmock DP, Funke BH, Gowrisankar S, Hegde MR, Kulkarni S, Mason CE, Nagarajan R, Voelkerding KV, Worthey EA, Aziz N, Barnes J, et al. Good laboratory practice for clinical next-generation sequencing informatics pipelines. Nature Biotechnology. 33: 689-93. PMID 26154004 DOI: 10.1038/nbt.3237  0.48
2015 Hagemann IS, Devarakonda S, Lockwood CM, Spencer DH, Guebert K, Bredemeyer AJ, Al-Kateb H, Nguyen TT, Duncavage EJ, Cottrell CE, Kulkarni S, Nagarajan R, Seibert K, Baggstrom M, Waqar SN, et al. Clinical next-generation sequencing in patients with non-small cell lung cancer. Cancer. 121: 631-9. PMID 25345567 DOI: 10.1002/cncr.29089  0.48
2015 Aziz N, Zhao Q, Bry L, Driscoll DK, Funke B, Gibson JS, Grody WW, Hegde MR, Hoeltge GA, Leonard DG, Merker JD, Nagarajan R, Palicki LA, Robetorye RS, Schrijver I, et al. College of American Pathologists' laboratory standards for next-generation sequencing clinical tests. Archives of Pathology & Laboratory Medicine. 139: 481-93. PMID 25152313 DOI: 10.5858/arpa.2014-0250-CP  0.48
2014 Cottrell CE, Al-Kateb H, Bredemeyer AJ, Duncavage EJ, Spencer DH, Abel HJ, Lockwood CM, Hagemann IS, O'Guin SM, Burcea LC, Sawyer CS, Oschwald DM, Stratman JL, Sher DA, Johnson MR, ... ... Nagarajan R, et al. Validation of a next-generation sequencing assay for clinical molecular oncology. The Journal of Molecular Diagnostics : Jmd. 16: 89-105. PMID 24211365 DOI: 10.1016/j.jmoldx.2013.10.002  0.48
2014 Nagarajan R. Reporting Software Clinical Genomics. 231-239. DOI: 10.1016/B978-0-12-404748-8.00014-9  0.48
2013 Chang LW, Viader A, Varghese N, Payton JE, Milbrandt J, Nagarajan R. An integrated approach to characterize transcription factor and microRNA regulatory networks involved in Schwann cell response to peripheral nerve injury. Bmc Genomics. 14: 84. PMID 23387820 DOI: 10.1186/1471-2164-14-84  0.72
2012 Wartman LD, Welch JS, Uy GL, Klco JM, Lamprecht T, Varghese N, Nagarajan R, Ley TJ. Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice. Plos One. 7: e46529. PMID 23056333 DOI: 10.1371/journal.pone.0046529  0.72
2012 Hucthagowder V, Meyer R, Mullins C, Nagarajan R, DiPersio JF, Vij R, Tomasson MH, Kulkarni S. Resequencing analysis of the candidate tyrosine kinase and RAS pathway gene families in multiple myeloma. Cancer Genetics. 205: 474-8. PMID 22939401 DOI: 10.1016/j.cancergen.2012.06.007  0.72
2012 Welch JS, Ley TJ, Link DC, Miller CA, Larson DE, Koboldt DC, Wartman LD, Lamprecht TL, Liu F, Xia J, Kandoth C, Fulton RS, McLellan MD, Dooling DJ, Wallis JW, ... ... Nagarajan R, et al. The origin and evolution of mutations in acute myeloid leukemia. Cell. 150: 264-78. PMID 22817890 DOI: 10.1016/j.cell.2012.06.023  0.72
2012 Shimoyama M, Nigam R, McIntosh LS, Nagarajan R, Rice T, Rao DC, Dwinell MR. Three ontologies to define phenotype measurement data. Frontiers in Genetics. 3: 87. PMID 22654893 DOI: 10.3389/fgene.2012.00087  0.72
2012 Cottler LB, Nagarajan R. Real-time assessment of community health needs and concerns. Science Translational Medicine. 4: 119mr2. PMID 22301551 DOI: 10.1126/scitranslmed.3003367  0.72
2011 Viader A, Chang LW, Fahrner T, Nagarajan R, Milbrandt J. MicroRNAs modulate Schwann cell response to nerve injury by reinforcing transcriptional silencing of dedifferentiation-related genes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17358-69. PMID 22131398 DOI: 10.1523/JNEUROSCI.3931-11.2011  0.72
2011 Deshmukh H, Yu J, Shaik J, MacDonald TJ, Perry A, Payton JE, Gutmann DH, Watson MA, Nagarajan R. Identification of transcriptional regulatory networks specific to pilocytic astrocytoma. Bmc Medical Genomics. 4: 57. PMID 21745356 DOI: 10.1186/1755-8794-4-57  0.72
2011 Link DC, Schuettpelz LG, Shen D, Wang J, Walter MJ, Kulkarni S, Payton JE, Ivanovich J, Goodfellow PJ, Le Beau M, Koboldt DC, Dooling DJ, Fulton RS, Bender RH, Fulton LL, ... ... Nagarajan R, et al. Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML. Jama. 305: 1568-76. PMID 21505135 DOI: 10.1001/jama.2011.473  0.72
2011 Jones EA, Lopez-Anido C, Srinivasan R, Krueger C, Chang LW, Nagarajan R, Svaren J. Regulation of the PMP22 gene through an intronic enhancer. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4242-50. PMID 21411665 DOI: 10.1523/JNEUROSCI.5893-10.2011  0.72
2011 Yu J, Deshmukh H, Payton JE, Dunham C, Scheithauer BW, Tihan T, Prayson RA, Guha A, Bridge JA, Ferner RE, Lindberg GM, Gutmann RJ, Emnett RJ, Salavaggione L, Gutmann DH, ... Nagarajan R, et al. Array-based comparative genomic hybridization identifies CDK4 and FOXM1 alterations as independent predictors of survival in malignant peripheral nerve sheath tumor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 1924-34. PMID 21325289 DOI: 10.1158/1078-0432.CCR-10-1551  0.72
2011 Welch JS, Klco JM, Varghese N, Nagarajan R, Ley TJ. Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice. Blood. 117: 2460-8. PMID 21190992 DOI: 10.1182/blood-2010-08-300087  0.72
2010 Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch J, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, ... ... Nagarajan R, et al. DNMT3A mutations in acute myeloid leukemia. The New England Journal of Medicine. 363: 2424-33. PMID 21067377 DOI: 10.1056/NEJMoa1005143  0.72
2010 Jang SW, Srinivasan R, Jones EA, Sun G, Keles S, Krueger C, Chang LW, Nagarajan R, Svaren J. Locus-wide identification of Egr2/Krox20 regulatory targets in myelin genes. Journal of Neurochemistry. 115: 1409-20. PMID 21044070 DOI: 10.1111/j.1471-4159.2010.07045.x  0.72
2010 Fehniger TA, Wylie T, Germino E, Leong JW, Magrini VJ, Koul S, Keppel CR, Schneider SE, Koboldt DC, Sullivan RP, Heinz ME, Crosby SD, Nagarajan R, Ramsingh G, Link DC, et al. Next-generation sequencing identifies the natural killer cell microRNA transcriptome. Genome Research. 20: 1590-604. PMID 20935160 DOI: 10.1101/gr.107995.110  0.72
2010 Ramsingh G, Koboldt DC, Trissal M, Chiappinelli KB, Wylie T, Koul S, Chang LW, Nagarajan R, Fehniger TA, Goodfellow P, Magrini V, Wilson RK, Ding L, Ley TJ, Mardis ER, et al. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. Blood. 116: 5316-26. PMID 20876853 DOI: 10.1182/blood-2010-05-285395  0.72
2010 Wentz AE, d'Avignon DA, Weber ML, Cotter DG, Doherty JM, Kerns R, Nagarajan R, Reddy N, Sambandam N, Crawford PA. Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment. The Journal of Biological Chemistry. 285: 24447-56. PMID 20529848 DOI: 10.1074/jbc.M110.100651  0.72
2009 Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K, Koboldt DC, Fulton RS, Delehaunty KD, McGrath SD, Fulton LA, Locke DP, Magrini VJ, Abbott RM, Vickery TL, ... ... Nagarajan R, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. The New England Journal of Medicine. 361: 1058-66. PMID 19657110 DOI: 10.1056/NEJMoa0903840  0.48
2009 Walter MJ, Payton JE, Ries RE, Shannon WD, Deshmukh H, Zhao Y, Baty J, Heath S, Westervelt P, Watson MA, Tomasson MH, Nagarajan R, O'Gara BP, Bloomfield CD, Mrózek K, et al. Acquired copy number alterations in adult acute myeloid leukemia genomes. Proceedings of the National Academy of Sciences of the United States of America. 106: 12950-5. PMID 19651600 DOI: 10.1073/pnas.0903091106  0.72
2009 Bernstam EV, Hersh WR, Johnson SB, Chute CG, Nguyen H, Sim I, Nahm M, Weiner MG, Miller P, DiLaura RP, Overcash M, Lehmann HP, Eichmann D, Athey BD, Scheuermann RH, ... ... Nagarajan R, et al. Synergies and distinctions between computational disciplines in biomedical research: perspective from the Clinical andTranslational Science Award programs. Academic Medicine : Journal of the Association of American Medical Colleges. 84: 964-70. PMID 19550198 DOI: 10.1097/ACM.0b013e3181a8144d  0.48
2009 Payton JE, Grieselhuber NR, Chang LW, Murakami M, Geiss GK, Link DC, Nagarajan R, Watson MA, Ley TJ. High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples. The Journal of Clinical Investigation. 119: 1714-26. PMID 19451695 DOI: 10.1172/JCI38248  0.48
2009 Baloh RH, Strickland A, Ryu E, Le N, Fahrner T, Yang M, Nagarajan R, Milbrandt J. Congenital hypomyelinating neuropathy with lethal conduction failure in mice carrying the Egr2 I268N mutation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2312-21. PMID 19244508 DOI: 10.1523/JNEUROSCI.2168-08.2009  0.48
2009 Sim I, Chute CG, Lehmann H, Nagarajan R, Nahm M, Scheuermann RH. Keeping raw data in context. Science (New York, N.Y.). 323: 713. PMID 19197039 DOI: 10.1126/science.323.5915.713a  0.48
2008 Freimuth RR, Schauer MW, Lodha P, Govindrao P, Nagarajan R, Chute CG. caBIG compatibility review system: software to support the evaluation of applications using defined interoperability criteria. Amia ... Annual Symposium Proceedings / Amia Symposium. Amia Symposium. 197-201. PMID 18999296  0.48
2008 Gysbers M, Reichley R, Kilbridge PM, Noirot L, Nagarajan R, Dunagan WC, Bailey TC. Natural language processing to identify adverse drug events. Amia ... Annual Symposium Proceedings / Amia Symposium. Amia Symposium. 961. PMID 18999130  0.48
2008 Ley TJ, Mardis ER, Ding L, Fulton B, McLellan MD, Chen K, Dooling D, Dunford-Shore BH, McGrath S, Hickenbotham M, Cook L, Abbott R, Larson DE, Koboldt DC, Pohl C, ... ... Nagarajan R, et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature. 456: 66-72. PMID 18987736 DOI: 10.1038/nature07485  0.48
2008 Ryu EJ, Yang M, Gustin JA, Chang LW, Freimuth RR, Nagarajan R, Milbrandt J. Analysis of peripheral nerve expression profiles identifies a novel myelin glycoprotein, MP11. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7563-73. PMID 18650334 DOI: 10.1523/JNEUROSCI.1659-08.2008  0.48
2008 Deshmukh H, Yeh TH, Yu J, Sharma MK, Perry A, Leonard JR, Watson MA, Gutmann DH, Nagarajan R. High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas. Oncogene. 27: 4745-51. PMID 18408760 DOI: 10.1038/onc.2008.110  0.48
2008 Chang LW, Payton JE, Yuan W, Ley TJ, Nagarajan R, Stormo GD. Computational identification of the normal and perturbed genetic networks involved in myeloid differentiation and acute promyelocytic leukemia. Genome Biology. 9: R38. PMID 18291030 DOI: 10.1186/gb-2008-9-2-r38  0.48
2008 Tomasson MH, Xiang Z, Walgren R, Zhao Y, Kasai Y, Miner T, Ries RE, Lubman O, Fremont DH, McLellan MD, Payton JE, Westervelt P, DiPersio JF, Link DC, Walter MJ, ... ... Nagarajan R, et al. Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood. 111: 4797-808. PMID 18270328 DOI: 10.1182/blood-2007-09-113027  0.48
2008 Xiang Z, Zhao Y, Mitaksov V, Fremont DH, Kasai Y, Molitoris A, Ries RE, Miner TL, McLellan MD, DiPersio JF, Link DC, Payton JE, Graubert TA, Watson M, Shannon W, ... ... Nagarajan R, et al. Identification of somatic JAK1 mutations in patients with acute myeloid leukemia. Blood. 111: 4809-12. PMID 18160671 DOI: 10.1182/blood-2007-05-090308  0.48
2007 Jones EA, Jang SW, Mager GM, Chang LW, Srinivasan R, Gokey NG, Ward RM, Nagarajan R, Svaren J. Interactions of Sox10 and Egr2 in myelin gene regulation. Neuron Glia Biology. 3: 377-87. PMID 18634568 DOI: 10.1017/S1740925X08000173  0.48
2007 Ellis MJ, Dixon M, Dowsett M, Nagarajan R, Mardis E. A luminal breast cancer genome atlas: progress and barriers. The Journal of Steroid Biochemistry and Molecular Biology. 106: 125-9. PMID 17826627 DOI: 10.1016/j.jsbmb.2007.05.011  0.48
2007 Chang LW, Fontaine BR, Stormo GD, Nagarajan R. PAP: a comprehensive workbench for mammalian transcriptional regulatory sequence analysis. Nucleic Acids Research. 35: W238-44. PMID 17517777 DOI: 10.1093/nar/gkm308  0.48
2007 Link DC, Kunter G, Kasai Y, Zhao Y, Miner T, McLellan MD, Ries RE, Kapur D, Nagarajan R, Dale DC, Bolyard AA, Boxer LA, Welte K, Zeidler C, Donadieu J, et al. Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia. Blood. 110: 1648-55. PMID 17494858 DOI: 10.1182/blood-2007-03-081216  0.48
2007 Sharma MK, Mansur DB, Reifenberger G, Perry A, Leonard JR, Aldape KD, Albin MG, Emnett RJ, Loeser S, Watson MA, Nagarajan R, Gutmann DH. Distinct genetic signatures among pilocytic astrocytomas relate to their brain region origin. Cancer Research. 67: 890-900. PMID 17283119 DOI: 10.1158/0008-5472.CAN-06-0973  0.48
2006 Chang LW, Nagarajan R, Magee JA, Milbrandt J, Stormo GD. A systematic model to predict transcriptional regulatory mechanisms based on overrepresentation of transcription factor binding profiles. Genome Research. 16: 405-13. PMID 16449500 DOI: 10.1101/gr.4303406  0.48
2005 Le N, Nagarajan R, Wang JY, Svaren J, LaPash C, Araki T, Schmidt RE, Milbrandt J. Nab proteins are essential for peripheral nervous system myelination. Nature Neuroscience. 8: 932-40. PMID 16136673 DOI: 10.1038/nn1490  0.48
2005 Le N, Nagarajan R, Wang JY, Araki T, Schmidt RE, Milbrandt J. Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination. Proceedings of the National Academy of Sciences of the United States of America. 102: 2596-601. PMID 15695336 DOI: 10.1073/pnas.0407836102  0.48
2004 Walter MJ, Park JS, Lau SK, Li X, Lane AA, Nagarajan R, Shannon WD, Ley TJ. Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures. Molecular and Cellular Biology. 24: 10882-93. PMID 15572690 DOI: 10.1128/MCB.24.24.10882-10893.2004  0.48
2003 Young AP, Nagarajan R, Longmore GD. Mechanisms of transcriptional regulation by Rb-E2F segregate by biological pathway. Oncogene. 22: 7209-17. PMID 14562049 DOI: 10.1038/sj.onc.1206804  0.48
2002 Modur V, Nagarajan R, Evers BM, Milbrandt J. FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer. The Journal of Biological Chemistry. 277: 47928-37. PMID 12351634 DOI: 10.1074/jbc.M207509200  0.48
2002 Nagarajan R, Le N, Mahoney H, Araki T, Milbrandt J. Deciphering peripheral nerve myelination by using Schwann cell expression profiling. Proceedings of the National Academy of Sciences of the United States of America. 99: 8998-9003. PMID 12084938 DOI: 10.1073/pnas.132080999  0.48
2002 Gutmann DH, Hedrick NM, Li J, Nagarajan R, Perry A, Watson MA. Comparative gene expression profile analysis of neurofibromatosis 1-associated and sporadic pilocytic astrocytomas. Cancer Research. 62: 2085-91. PMID 11929829  0.48
2001 Araki T, Nagarajan R, Milbrandt J. Identification of genes induced in peripheral nerve after injury. Expression profiling and novel gene discovery. The Journal of Biological Chemistry. 276: 34131-41. PMID 11427537 DOI: 10.1074/jbc.M104271200  0.48
2001 Nagarajan R, Svaren J, Le N, Araki T, Watson M, Milbrandt J. EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression. Neuron. 30: 355-68. PMID 11394999 DOI: 10.1016/S0896-6273(01)00282-3  0.48
2000 Tourtellotte WG, Nagarajan R, Bartke A, Milbrandt J. Functional compensation by Egr4 in Egr1-dependent luteinizing hormone regulation and Leydig cell steroidogenesis. Molecular and Cellular Biology. 20: 5261-8. PMID 10866682 DOI: 10.1128/MCB.20.14.5261-5268.2000  0.48
1999 Tourtellotte WG, Nagarajan R, Auyeung A, Mueller C, Milbrandt J. Infertility associated with incomplete spermatogenic arrest and oligozoospermia in Egr4-deficient mice. Development (Cambridge, England). 126: 5061-71. PMID 10529423  0.48
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